Developing a web-based LGBT cultural competency training for oncologists: The COLORS training.

OBJECTIVE: Despite substantial LGBT cancer health disparities, there are no LGBT cultural competency trainings tailored for oncologists. Here we describe the systematic development of a web-based, oncology-focused LGBT cultural competency training. METHODS: A literature review regarding LGBT cancer outcomes and competency training was conducted to identify potential training content. An expert panel meeting, including LGBT cancer survivors, cultural competency experts, oncologists, a web designer, and an instructional designer, was held to solidify the training content focus. Following the panel, the training was developed in collaboration with an instructional designer, a web designer, and LGBT community members. RESULTS: The training modules include: 1) LGBT Basics; 2) Inclusive Environments; 3) Initiating Oncology Care with LGBT Patients; and 4) Issues in Cancer Survivorship among LGBT Patients. Module content is interactive, and models effective communication. CONCLUSION: The process of collaboration with a diverse group of stakeholders and three cancer centers in Florida has resulted in a practical and efficient web-based resource for LGBT cultural competency training for oncologists. PRACTICE IMPLICATIONS: Feedback from stakeholders indicates that training in this area is needed and will be well-received by oncologists. We are currently conducting an evaluation of this training among oncologists and LGBT community members.

Characterization and Therapeutic Uses of Exosomes: A New Potential Tool in Orthopedics.

In recent years, regenerative medicine has directed its interests onto the use of stem cells to heal human tissues. One specific class of cells that has been used in this field of research is mesenchymal stem cells (MSCs). Because of difficulties with the usage of whole stem cells, researchers have turned to an alternative, the secretome of the MSCs. In recent years, research has explored numerous aspects of the MSC secretome, especially the most promising aspect, exosomes. This review explores a variety of interests in exosomes including the classification and molecular composition of exosomes, mechanisms for exosome isolation, and the various biological functions of exosomes. As more is discovered about the exosomes, their different diagnostic and therapeutic uses in the medical field have also been explored. A new field attempting to exploit the exosomes in clinical practice is orthopedics. Although a significant deal of research has been carried out, even more is being discovered to allow utilization of the exosomes in clinical practice.