Subject(s)
Drug Resistance, Neoplasm/physiology , Janus Kinase 2/genetics , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy , Myeloproliferative Disorders/diagnosis , Piperazines/therapeutic use , Pyrimidines/therapeutic use , Thrombocytosis/chemically induced , Aged, 80 and over , Amino Acid Substitution/physiology , Antineoplastic Agents/therapeutic use , Benzamides , Drug Resistance, Neoplasm/genetics , Female , Humans , Imatinib Mesylate , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/complications , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics , Male , Middle Aged , Myeloproliferative Disorders/complications , Myeloproliferative Disorders/genetics , Phenylalanine/genetics , Thrombocytosis/genetics , Valine/geneticsABSTRACT
We report one case of unilateral ovarian Sertoli-Leydig tumor with intermediate grade and heterologous element, in a young woman with clinical and biological typical presentation. We discuss 2D and 3D ultrasonographic and doppler features.
Subject(s)
Ovarian Neoplasms/diagnostic imaging , Sertoli-Leydig Cell Tumor/diagnostic imaging , Ultrasonography, Doppler/methods , Adult , Female , Humans , Imaging, Three-Dimensional , Ovarian Neoplasms/pathology , Sertoli-Leydig Cell Tumor/pathologyABSTRACT
BACKGROUND: The solitary fibrous tumor (SFT) is a spindle-cell tumor that very rarely involves the orbit. We report a new case that we compare to reports in the literature. CASE: A 72-year-old woman presented a conjunctival inflammation of the right eye developing over 5 months with progressive proptosis. Magnetic resonance imaging revealed an extraconal and homogeneous mass, which showed hypointensity on T1-weighted images and hyperintensity on T2-weighted images, without specificity. Histological examination of the lesion removed by anterior orbitotomy confirmed the diagnosis of the SFT of the orbit. The patient was doing well without recurrence after 9 months. DISCUSSION: The diagnosis of SFT is histological. It is a mesenchymal tumor. Immunohistochemically, the tumor cells are strongly positive for CD34 and vimentin. CONCLUSION: The SFT of the orbit is a very rare and generally benign tumor. It must be immunohistochemically differentiated from other spindle-cell tumors of the orbit. The treatment is a complete surgical excision, and long-term follow-up is necessary because recurrence may appear long after treatment.