ABSTRACT
Background: Venous leg ulcers severely affect patients' quality of life due to its high morbidity and recurrent nature. Currently, compression therapy is the first-line treatment for venous leg ulcers. Aim: This study sought to evaluate the efficacy of the Mobiderm® technology developed by Thuasne in a prospective case series of venous leg ulcers. Methods: Nine patients (N = 9) with venous leg ulcers were enrolled into this case series. Mobiderm® bandage was applied on to the affected limbs of the patients in the multi-component bandages system. The bandages were changed as frequent as the patients had their wound dressing for their standard treatment in a 12-week duration. Wound size and calf circumference were measured at week 0 and week 12. Paired sample t-test was used to compare the mean values of wound size and calf circumference pre- and post-treatment. Results: Reductions in wound size and calf circumference were observed in all nine patients (100%). Five patients were evaluable at week 12. The wound sizes significantly reduced by 27.2% to 53.2% (p = 0.02), and the calf circumferences significantly reduced by 3.2% to 26.0% (p = 0.02) after 12 weeks (N = 5). Safety was unremarkable, with no occurrence of treatment-emergent-related adverse event. Conclusion: Mobiderm® bandage was reported to be effective in promoting wound healing and reducing swelling, suggesting it to be integrated in the compression therapy for the management of venous leg ulcers.
Subject(s)
Plastic Surgery Procedures , Varicose Ulcer , Humans , Varicose Ulcer/therapy , Quality of Life , Bandages , Wound HealingABSTRACT
@#Retention phase is fundamental in orthodontic treatment. Around 70% of patients are subjected to relapse postorthodontic treatment. The risk of relapse can be minimized by prescribing a retainer suitable to a patient’s pre-treatment clinical condition and based on retention characteristics of retainers. When removable retainers are prescribed, responsibility of maintaining tooth stability lies on patients. Recent idea has been proposed that removable retainer should be worn indefinitely in order to maintain the treatment result. Therefore, the understanding of retention characteristics of removable retainers is important for promoting patient compliance and satisfaction. This article focuses on reviewing the use of removable retainers in relation to preferences among clinicians, patient acceptability, effectiveness, compliance, as well as retention regimes. An electronic search was conducted in the PubMed/MEDLINE, ScienceDirect and Scopus database. The search was performed up to June 2020 using a variety of keywords including orthodontic retainers, Hawley, vacuum formed and retention. Among the 248 publications that were initially searched, total of 56 publications were finally included. Twenty-seven were observational (6 prospective; 16 cross-sectional, 4 retrospective, and 1 case series), fourteen experimental, fourteen review articles, and one opinion piece. Although quite a number of reviews on removable retainers were available, several significant papers have been published recently. Furthermore, a guideline on retention regime is warranted.