ABSTRACT
A content of a biliary ways microflora and its correlation with clinical form and severity of inflammatory-destructive processes in hepatopancreatobiliary zone were studied up. The investigation objective was the optimization of a treatment--diagnostic tactics for the complications and remote recurrences rate reduction in a complicated biliary calculous disease. There was established, that a standard bacteriological investigation do not give a possibility to estimate some causes of a biliary ducts affection, a chlamidial infection in particular. So on, for the individual antibacterial therapy choosing a more detailed and modern examination of patients is needed.
Subject(s)
Antibodies, Bacterial/blood , Chlamydia Infections/diagnosis , Chlamydia/isolation & purification , Cholecystitis/diagnosis , Hepatitis/diagnosis , Pancreatitis/diagnosis , Pelvic Inflammatory Disease/diagnosis , Peritonitis/diagnosis , Adult , Anti-Bacterial Agents/therapeutic use , Biliary Tract/microbiology , Biliary Tract/pathology , Biliary Tract Surgical Procedures , Chlamydia/growth & development , Chlamydia/pathogenicity , Chlamydia Infections/drug therapy , Chlamydia Infections/microbiology , Chlamydia Infections/surgery , Cholecystitis/drug therapy , Cholecystitis/microbiology , Cholecystitis/surgery , Diagnosis, Differential , Female , Hepatitis/drug therapy , Hepatitis/microbiology , Hepatitis/surgery , Humans , Immunoglobulin G/blood , Immunoglobulin M/blood , Liver/microbiology , Liver/pathology , Male , Middle Aged , Pancreas/microbiology , Pancreas/pathology , Pancreas/surgery , Pancreatitis/drug therapy , Pancreatitis/microbiology , Pancreatitis/surgery , Pelvic Inflammatory Disease/drug therapy , Pelvic Inflammatory Disease/microbiology , Pelvic Inflammatory Disease/surgery , Peritonitis/drug therapy , Peritonitis/microbiology , Peritonitis/surgery , Severity of Illness IndexABSTRACT
Expression of alpha-receptors of estrogen (RE) in accordance to immunohistochemical (IHC) labeling in gastroduodenal mucosa cells was studied up in patients, suffering the ulcer disease and without it. In 4 patients (group I) a gastroduodenal mucosa affection was revealed, they were operated on for hemorrhage from gastroduodenal ulcers; in 3 patients (group II) gastroduodenal mucosa affection was not observed; in 4 patients (group III, control), a mammary gland cancer was diagnosed, a positive reaction on alpha-RE was noted. In groups I and II the biopsies were studied, obtained from pylorus and gastric fundus, as well as from duodenal ampula, and in a group III--obtained from the tumor. In a control group a positive labeling of nuclei was revealed in biopsies. In patients of groups I and II the alpha-RE expression by cellular nuclei was not revealed, but, the lots of positive IHC labeling of cytoplasm in glandular and stromal mucosal cells of the investigated gut were noted. Positive IHC labeling of cytoplasm for alpha-RE witnesses about sensitivity to them in norma and pathological processes. But, a trustworthy difference of alpha-RE expression by cellular nuclei was not noted. For confirmation or denial of this hypothesis further clinical and IHC investigations are needed.
