ABSTRACT
The paper analyzes data on how physical exercise as a standard test of cosmonaut's performance, affects the renal function and urine protein profile. The investication involved 10 normal human subjects. Following exercise, rate of renal excretion of proteins increased. The occurrence of 4 proteins out of 9 in urine did not alter and of 2 (alpha-methylacyl coenzyme A racemase and cubilin) increased; occurrence of 3 proteins (kallikrein-1, osteopontin and vitamin K-dependent protein Z) decreased. Out of 24 proteins with molecular weights higher than albumin, 7 were detected in urine after exercise more frequently, 6 with same frequency as before the test and none less frequently which demonstrates lowered selectivity of the glomerular barrier during exercise.
