Analysis of the Volumetric Asymmetry of the Mandibular Condyles Using CBCT.

OBJECTIVES: The aim of this study was to analyse volumetric asymmetries between the right and left condyles in relation to age, gender, and dental status. MATERIALS AND METHODS: A retrospective analysis of 150 cone beam computed tomography (CBCT) scans was conducted. A single investigator performed the volumetric analysis of the CBCT scans using Vesalius 3D software. The volumetric data were analysed in relation to the gender, age, and dental status. RESULTS: The mean right condylar volume was significantly higher (P < .01) than the left condylar volume. Right and left condylar volumes were significantly higher (P < .01) in male study participants when compared to female study participants. There was no significant difference (P = .47) in the volumetric asymmetry between the male and female study participants. The volumetric asymmetry was significantly higher (P < .01) in the older age groups when compared to the younger age groups. The volumetric asymmetry was significantly higher (P < .01) in the partially and completely edentulous patients when compared to the dentate study participants. The condylar volume on the side having a partially edentulous area was significantly lower than the condylar volume of the contralateral dentate side (P < .001). CONCLUSIONS: The volumetric asymmetry between the right and left condyle significantly increases with age and edentulousness. The result of the study encourages the clinicians to perform volumetric evaluation of the condyles in cases of radiographically evident condylar asymmetries to obtain a more accurate diagnosis.

Knowledge, attitude and practice of dental house surgeons and undergraduate students towards radiation safety and protection: A questionnaire based survey.

OBJECTIVE: Ionizing radiation is hazardous to living tissues due to their effects on somatic cells and genetic material. Since dental radiography is used widely for diagnosis, treatment planning and patient education, it is important for dentists to understand the problems associated with the use of radiation and the methods of preventing them. The present study was designed to assess and compare the knowledge, attitude and practice of dental house surgeons and undergraduate students towards radiation safety and protection. MATERIALS AND METHODS: A cross sectional questionnaire based survey was conducted among 153 dental house surgeons and undergraduate students attending a dental teaching hospital. RESULTS: On comparison of the house surgeons with undergraduate students, the present study found that the knowledge, attitude and practice of house surgeons were better than the undergraduate students regarding AERB guidelines, ALARA principles, position distance rule, personal monitoring devices, thickness of lead barrier and use of lead protection. Both the groups had similar high knowledge regarding the harmful effects of X-rays. However undergraduate students had better knowledge regarding radiation hazard symbol and made better use of personal monitoring devices. A greater number of house surgeons were found to have had formal training in radiation protection while undergraduate students were more willing to undergo further training. CONCLUSION: Dental students must be educated regarding radiation safety and protection before they commense work as independent practitioners for the protection of their patients, the environment and themselves.

Evaluation of salivary tumour necrosis factor-alpha in patients with recurrent aphthous stomatitis.

PURPOSE: Present study was undertaken to evaluate and compare the salivary levels of tumour necrosis factor alpha (TNF-α) in subjects with RAS, traumatic ulcers (TUs) in the oral mucosa and in healthy controls. MATERIALS AND METHODS: Present study involved 90 participants of which 30 subjects were diagnosed with RAS, 30 subjects with TUs and 30 healthy controls grouped as group 1, group 2 and group 3 respectively. Unstimulated saliva was collected from the subjects through 'Spit Technique' and the estimation of TNF-α was done by enzyme linked immunosorbent assay. The data collected was statistically analysed. RESULTS: Salivary level of TNF-α was significantly higher in RAS patients than in patients with TUs and healthy controls. Difference between the Salivary TNF-α level in our study groups were statistically significant (p<0.001). CONCLUSION: Present study suggests that saliva is a convenient and ideal medium for the detection of TNF-α. Statistically significant difference in the level of salivary TNF-α between the RAS and TUs subjects as well as controls suggests the significant contribution of TNF-α in pathogenesis of RAS.

Status of thiocyanate levels in the serum and saliva of non-smokers, ex-smokers and smokers.

BACKGROUND: Use of tobacco is often implicated in the development of oral diseases. Questionable accuracy of the traditional questionnaires to assess cigarette exposure necessitates the use of biomarkers like thiocyanate which provide a definitive quantitative measure. OBJECTIVE: To assess the rise in the level of thiocyanate for measurement of smoking behaviour in adults. MATERIALS AND METHODS: Serum and salivary thiocyanate levels were estimated in 20 non-smokers, 20 ex-smokers and 40 smokers. Smokers were divided into two groups based on the presence or absence of oral mucosal lesions. RESULTS: The mean serum and salivary thiocyanate levels were increased significantly in smokers when compared to non-smokers and ex-smokers. The levels were not significantly different between ex-smokers and non-smokers and between smokers with tobacco related oral mucosal lesions and those without. Statistically significant correlation was seen between the serum and salivary levels of thiocyanate. CONCLUSION: This study highlights the high level of thiocyanate in the serum and saliva of smokers when compared to non-smokers and ex-smokers. Significant increase in thiocyanate level was also seen in saliva. Hence it can be stated that saliva can be used as a reliable, non-invasive tool to assess smoking behaviour in the population and its changes over time.

Status of Serum and Salivary Levels of Superoxide Dismutase in Type 2 Diabetes Mellitus with Oral Manifestations: A Case Control Study.

BACKGROUND: Type 2 Diabetes Mellitus is a very well known metabolic disorder that has reached epidemic proportions worldwide. Evidence suggests that oxidative stress increases in Diabetes Mellitus because of the excessive production of reactive oxygen species and an impaired antioxidant defence mechanism. This study estimated, compared and correlated the serum and salivary Superoxide dismutase levels in healthy subjects and subjects with Type 2 Diabetes Mellitus having oral manifestations. MATERIALS AND METHODS: In this study, serum and salivary Superoxide dismutase levels were estimated in 45 healthy subjects and 45 patients with Type 2 Diabetes Mellitus with oral manifestations. RESULTS: The mean serum and salivary Superoxide dismutase levels were significantly decreased in subjects with Type 2 Diabetes Mellitus with oral manifestations compared to the healthy subjects. Positive correlation in both healthy and diabetics was observed between serum and salivary samples. CONCLUSION: This study highlights that the abnormally high levels of oxidative stress in diabetics coupled with simultaneous decline in antioxidant defence mechanism results in complications in Diabetes mellitus. Thus exploring saliva for antioxidant markers that accurately reflect the redox status of the body is worthwhile.