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1.
J Coll Physicians Surg Pak ; 34(4): 390-393, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38576278

ABSTRACT

OBJECTIVE: To evaluate the efficacy of dexamethasone as a final intracanal rinse in relieving postoperative pain of teeth with symptomatic irreversible pulpitis. STUDY DESIGN: Randomised controlled trial. Place and Duration of the Study: Department of Operative Dentistry, PIMS, Islamabad, Pakistan, from June 2019 to December 2020. METHODOLOGY: Sixty patients aged 18- 50 years diagnosed with symptomatic irreversible pulpitis were selected according to the inclusion criterion. After obtaining informed consent, root canal therapy (RCT) was initiated under rubber dam. Pulpectomy was done followed by canal preparation. The lottery method was utilised for the division of patients. Group A (experimental) received dexamethasone (4mg/ml in 5ml syringe) as a final rinse, while Group B (control group) recalled after 1 week and asked whether their pain had relieved or not as a yes/no question. After data collection teeth were obturated and permanent restoration was placed. Data were analysed using Chi-square test. RESULTS: The efficacy of dexamethasone as a final intracanal rinse was greater than saline 86.67% and 20.0%, respectively (p < 0.05) in relieving postoperative pain in teeth with symptomatic irreversible pulpitis. CONCLUSION: Dexamethasone was proved to be more efficacious than saline in alleviating postoperative pain when used as a final intracanal rinse after canal instrumentation. KEY WORDS: Irreversible pulpitis, Dexamethasone, Postoperative pain, Pulpectomy.


Subject(s)
Pulpitis , Humans , Dexamethasone/therapeutic use , Pain, Postoperative/drug therapy , Pulpitis/surgery , Root Canal Preparation , Root Canal Therapy/methods , Adolescent , Young Adult , Adult , Middle Aged
2.
Int J Biol Macromol ; 2020 May 07.
Article in English | MEDLINE | ID: mdl-32389650

ABSTRACT

In the present study, a potential Guar gum/activated carbon nanocomposite as an adsorbent was synthesized and utilized for the sequestration of toxic congo red dye from synthetic wastewater. The nanocomposite was characterized using different techniques such as SEM, EDX, TEM, FTIR and XRD. Various physico-chemical parameters such as influence of contact time, pH, adsorbent dose, temperature and initial dye concentration were investigated to optimize conditions for maximum adsorption of congo red. Equilibrium data fitted well with Langmuir isotherm model having maximum adsorption capacity of 831.82 mgg-1 at 313 K. The kinetic studies demonstrated that the adsorption followed a pseudo-second order kinetic model. The thermodynamic study showed that the adsorption of congo red onto nanocomposite was spontaneous, exothermic with decreased in randomness at solid/liquid interface. The regeneration study indicated that the nanocomposite could be reused successfully upto five consecutive cycles. Therefore, the present material can be effectively and efficiently urilized for the removal of congo red dye from aqueous solution as well as industrial wastewater.

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