Assessing Engagement of Adolescents and Young Adults (AYA) in HIV Research: A Multi-method Analysis of a Crowdsourcing Open Call and Typology of AYA Engagement in Sub-Saharan Africa.

Engagement of adolescents and young adults (AYA) in HIV research is increasing in many settings. We organized a crowdsourcing open call to solicit examples of how AYA have been engaged in HIV research in Africa and to develop an engagement typology. We formed a steering committee, promoted the open call, organized judging and recognized finalists. We used a multi-methods approach to identify emerging themes and measure engagement. We received 95 entries from individuals in 15 countries; 74 met the eligibility criteria. More than three-quarters of entries were from AYA (55/74, 74%). Four themes characterized AYA engagement: (1) AYA were co-creators in the HIV research process. (2) AYA were involved in community-level capacity building. (3) AYA were co-leaders in minor risk research. (4) AYA used digital methods to enhance engagement. Our open call identified diverse methods of AYA engagement, which can enhance strategies used to reach AYA in African HIV studies.

Top 50 most cited articles in revision total hip arthroplasty research.

Background: Bibliometric analysis is a useful tool for measuring the scholarly impact of a topic. To date, there is no such review analyzing the characteristics and trends of publications focused on revision total hip arthroplasty (rTHA). The purpose of this study is to use bibliometric analysis to comprehensively analyze the 50 most cited articles in rTHA research. Methods: This is a cross-sectional study that used the ISI Web of Knowledge database to identify articles published before September 2021. Articles were sorted in descending order by number of citations and those with a focus of rTHA were identified. Of these, the top 50 most cited articles were carried forward for evaluation. Results: The 2000s (50%) and the 1990s (32%) had the greatest volume of contribution. 9 of the top 10 most cited articles were published in the 2000s. The highest impact article had 4702 citations. The level of evidence (LOE) published with the greatest frequency was LOE II (40%) followed by LOE III and LOE IV both recording 24%. The Journal of Bone and Joint Surgery-American Volume had the greatest productivity (46%) followed by The Journal of Bone and Joint Surgery-British Volume (18%). The United States was the country with the highest number of contributions to this list with 56% followed by England (12%), and Sweden and Canada both with 8%. Conclusion: The most impactful articles focusing on rTHA research were comprehensively and objectively analyzed. The most common article type was clinical outcomes (46%) followed by natural history/epidemiology (24%) and surgical technique (16%). While this topic is highly studied with significant level of evidence to support the studies, there is a lack of influential research regarding imaging and clinical guidelines. This analysis can be used by researchers to develop further discussions and build research questions.

Paraneoplastic Dermatomyositis.

Dermatomyositis and its association with malignancy is well known. Though many tumors like breast, ovary, lung carcinomas are reported to be associated with it, cervical carcinoma is a very rare one. Tumors in these patients are usually unmasked by abnormal findings in the medical history and physical examination. Here we report case of a postmenopausal female who presented with subacute onset of weakness of all four limbs. Treatment of the underlying tumor relieved the symptoms of dermatomyositis in our patient.

Intestinal infestation with Fasciolopsis buski leading to acute kidney injury.

Fasciolopsis buski is the largest intestinal fluke infecting human beings. This trematode is endemic in certain parts of the country. Migration poses the risk of spread of the worm to other parts of the country. We report fasciolopsis buski in a migrant from Bihar working in Coimbatore, Tamil Nadu. Acute kidney injury following intestinal obstruction occurred in this case which was never described before.