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au:"Oliveira de Santis, Jessica" (1)

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Cerebellar Neoplasms (1)

Medulloblastoma (1)

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Actions speak louder than ORFs: A non-canonical microprotein promotes medulloblastoma oncogenesis.

Delaidelli, Alberto; Oliveira de Santis, Jessica; Sorensen, Poul H.

Mol Cell ; 84(2): 188-190, 2024 Jan 18.

Article in English | MEDLINE | ID: mdl-38242097

ABSTRACT

In this issue of Molecular Cell, Hofman et al.1 identify the translation of a non-canonical upstream open reading frame of the ASNSD1 gene into a microprotein that supports medulloblastoma growth.

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Cerebellar Neoplasms , Medulloblastoma , Humans , Medulloblastoma/genetics , Open Reading Frames , Micropeptides , Carcinogenesis/genetics , Cell Transformation, Neoplastic/genetics , Cerebellar Neoplasms/genetics , Protein Biosynthesis

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