ABSTRACT
HLA-B*15:689, HLA-B*35:603 and HLA-B*49:01:25, three novel HLA class I alleles detected by next-generation sequencing.
Subject(s)
Alleles , Exons , High-Throughput Nucleotide Sequencing , Histocompatibility Testing , Humans , HLA-B35 Antigen/genetics , HLA-B15 Antigen/genetics , HLA-B15 Antigen/immunology , HLA-B Antigens/genetics , Sequence Analysis, DNA , Codon , Base Sequence , HLA-B39 Antigen/genetics , HLA-B39 Antigen/immunology , Tissue DonorsABSTRACT
Two novel HLA-DQB1 alleles, HLA-DQB1*05:01:50 and HLA-DQB1*06:486, characterised in bone marrow volunteers.
Subject(s)
Alleles , Exons , HLA-DQ beta-Chains , High-Throughput Nucleotide Sequencing , Humans , HLA-DQ beta-Chains/genetics , Histocompatibility Testing/methods , Base Sequence , Sequence Analysis, DNA/methods , Codon , Bone MarrowABSTRACT
Eight novel HLA class I alleles detected by next-generation sequencing.
Subject(s)
Alleles , High-Throughput Nucleotide Sequencing , Histocompatibility Antigens Class I , Histocompatibility Testing , Humans , High-Throughput Nucleotide Sequencing/methods , Histocompatibility Antigens Class I/genetics , Histocompatibility Antigens Class I/immunology , Histocompatibility Testing/methods , Exons/genetics , Sequence Analysis, DNA/methodsABSTRACT
Identification of two novel HLA alleles in Russian bone marrow donors.
Subject(s)
Alleles , Tissue Donors , Humans , Russia , HLA-A2 Antigen/genetics , HLA-A2 Antigen/immunology , Bone Marrow Transplantation , HLA-B40 Antigen/genetics , HLA-B40 Antigen/immunology , Exons , Histocompatibility Testing , Bone Marrow , Sequence Analysis, DNAABSTRACT
Five novel HLA-C alleles detected by next-generation sequencing: HLA-C*02:02:73, -C*03:04:106, -C*06:382, -C*07:1114Q and -C*12:408.
Subject(s)
Alleles , HLA-C Antigens , High-Throughput Nucleotide Sequencing , Histocompatibility Testing , Humans , High-Throughput Nucleotide Sequencing/methods , HLA-C Antigens/genetics , Histocompatibility Testing/methods , Exons , Sequence Analysis, DNA/methodsABSTRACT
HLA-A*01:454 and HLA-A*31:229, two novel HLA-A alleles detected during routine typing by next-generation sequencing.
Subject(s)
Alleles , Exons , HLA-A Antigens , High-Throughput Nucleotide Sequencing , Histocompatibility Testing , Humans , HLA-A Antigens/genetics , Sequence Analysis, DNA/methods , HLA-A1 Antigen/genetics , Base SequenceABSTRACT
Two novel HLA-DRB1 alleles were detected using next generation sequencing.
Subject(s)
Alleles , HLA-DRB1 Chains , High-Throughput Nucleotide Sequencing , Histocompatibility Testing , Humans , HLA-DRB1 Chains/genetics , Exons , Sequence Analysis, DNA/methods , Base SequenceABSTRACT
We identified two novel HLA-DQB1 alleles by NGS, HLA-DQB1*03:519 and HLA-DQB1*06:01:35.
Subject(s)
High-Throughput Nucleotide Sequencing , Humans , Alleles , HLA-DQ beta-Chains/geneticsABSTRACT
Identification of the novel HLA-A*02:1148 and HLA-B*44:386 alleles by next-generation sequencing.
Subject(s)
HLA-A Antigens , High-Throughput Nucleotide Sequencing , Humans , Alleles , HLA-B Antigens/geneticsABSTRACT
A novel HLA-C*07 allele, now officially designated HLA-C*07:02:150, was identified by next-generation sequencing.
Subject(s)
Genes, MHC Class I , HLA-C Antigens , Humans , HLA-C Antigens/genetics , Alleles , High-Throughput Nucleotide SequencingABSTRACT
Novel HLA-B*55:01:31, HLA-C*07:1113 alleles and confirmatory HLA-C*12:392 allele were detected during the HLA typing process.
Subject(s)
Genes, MHC Class I , HLA-C Antigens , Humans , Alleles , HLA-C Antigens/genetics , HLA-B Antigens/genetics , Histocompatibility TestingABSTRACT
A novel HLA-B*35 allele, officially designated HLA-B*35:594, was identified by next-generation sequencing.
Subject(s)
Alleles , Exons , High-Throughput Nucleotide Sequencing , Histocompatibility Testing , Humans , HLA-B35 Antigen/genetics , Sequence Analysis, DNA , Base Sequence , Codon , HLA-B Antigens/genetics , Tissue DonorsABSTRACT
We identified two novel HLA alleles by NGS, HLA-B*51:395 and HLA-DQB1*06:478.
Subject(s)
HLA-B Antigens , High-Throughput Nucleotide Sequencing , Humans , Alleles , HLA-DQ beta-Chains/genetics , HLA-B Antigens/geneticsABSTRACT
HLA-B*35:592 differs from HLA-B*35:03:01:01 by one nucleotide substitution in exon 4.
Subject(s)
Genes, MHC Class I , Nucleotides , Humans , Alleles , Base Sequence , Russia , Sequence Analysis, DNAABSTRACT
Characterization of the novel HLA-C*07:1093 allele in a Russian female bone marrow donor.
Subject(s)
HLA-C Antigens , Nucleotides , Humans , Female , HLA-C Antigens/genetics , Alleles , Histocompatibility Testing , Exons/genetics , Tissue DonorsABSTRACT
We identified two novel HLA class II alleles by next-generation sequencing, HLA-DRB1*12:107 and HLA-DQB1*06:476.
Subject(s)
High-Throughput Nucleotide Sequencing , Humans , HLA-DRB1 Chains/genetics , Gene Frequency , Alleles , Haplotypes , HLA-DQ beta-Chains/geneticsABSTRACT
Eighteen HLA allele sequences were confirmed and extended: 3 HLA-A, 6 HLA-B, 3 HLA-C, 2 HLA-DRB1, and 4 HLA-DQB1 alleles.
Subject(s)
Bone Marrow , HLA-A Antigens , Humans , Alleles , Gene Frequency , HLA-A Antigens/genetics , Haplotypes , HLA-DQ beta-Chains/genetics , HLA-B Antigens/genetics , HLA-DRB1 Chains/genetics , Registries , RussiaABSTRACT
Characterization of the novel HLA-C*07:1083 allele in a Russian bone marrow donor.
Subject(s)
Genes, MHC Class I , HLA-C Antigens , Humans , HLA-C Antigens/genetics , Base Sequence , Alleles , RussiaABSTRACT
The new HLA-DRB1*11:320, HLA-DRB1*15:218, HLA-DQB1*05:324 alleles characterized in bone marrow donors.
Subject(s)
HLA-DRB1 Chains , Humans , HLA-DRB1 Chains/genetics , Gene Frequency , Alleles , Haplotypes , HLA-DQ beta-Chains/geneticsABSTRACT
HLA-B*13:181 differs from HLA-B*13:02:01:01 by one nucleotide substitution in codon 72 in exon 2.