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OBJECTIVE: To explore the history and evolution of the William P. Didusch Museum. METHODS: We reviewed the literature and personal accounts regarding the founding of the museum and changes to the museum over its history. RESULTS: William P. Didusch was a world-renowned medical artist and was the staff artist for the Brady Urological Institute under Hugh Hampton Young. The William P. Didusch Museum was founded in 1971 and comprised the collection of Didusch's drawings and instruments, which were housed at the American Urological Association (AUA) headquarters. In 1972, Didusch became the museum's first curator. At the time of Didusch's death, the AUA purchased a new building and began extensive renovations. In 1987, Dr. William W. Scott, the museum's third curator, cataloged the items housed in the museum before it was reopened in 1989. Dr. Rainer Engel took over as curator in 1993 and supervised renovations to the exhibit area. In 2003, the museum moved to the new AUA Headquarters in Linthicum, Maryland, and the central exhibit on the history of the cystoscope was finalized. Under Dr. Ronald Rabinowitz as Historian, the museum history committee and leadership were restructured and included a website with a virtual museum tour, links to history exhibits, and a newsletter. CONCLUSION: The William P. Didusch Center for Urologic History continues to evolve in pursuit of its mission to document, preserve, and present the history of urology and to educate and engage the medical community and the public.
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INTRODUCTION: Pediatric urology is a subspecialty of urology that emerged from a culture in which children with urological disorders were cared for by general urologists and general pediatric surgeons. The development of pediatric urology as a subspecialty was years in the making, highlighted by individuals who recognized that children with urological conditions were not just "small adults," but required special experience and training. Subspecialization was initiated by persistent visionaries who recognized the need for a trained cadre of experts to provide better care for children. It took the coordinated effort of all subgroups and leaderships in pediatric urology to push these efforts over the goal line. The focus of this review is to highlight certain individuals who played major roles in this vision and to document the efforts of many to coordinate the pathways to sub-specialization. METHODS: The careers of Meredith F. Campbell and Frank B. Bicknell were researched to identify their rationale and roles in developing pediatric urology as a distinct medical specialty in the United States. In addition, the minutes of the meetings of the Pediatric Urology Advisory Council (PUAC) with the American Board of Urology (ABU) were reviewed. The origins of the Society for Pediatric Urology (SPU) and the American Academy of Pediatrics Section of Urology (AAP-SOU) were researched. The contributions of each to the certification of pediatric urology as a distinct subspecialty was delineated. RESULTS: Campbell was Chair of Urology at the New York University (NYU) School of Medicine and wrote prolifically about pediatric urology. He published one of the first practical textbooks in pediatric urology, almost completely self-written, in 1937. Bicknell, a general urologist in Michigan on the faculty at Wayne State University School of Medicine, led the initiative to create the Society for Pediatric Urology (SPU) that first met at the 1951 annual American Urological Association (AUA) meeting in Chicago and included nine attendees. Subsequently, John Lattimer (College of Physicians and Surgeons at Columbia University) organized a well-attended meeting of urologists interested in pediatrics at the 1964 annual AAP meeting in New York City. This led to the formation of the AAP Section on Urology. Integral to the justification for the development of a subspecialty was evidence of a published corpus of content. In addition to published textbooks devoted exclusively to pediatric urology, this was further fulfilled by the AAP Section on Urology Pediatric Supplement to the Journal of Urology, first published in 1986, and later with the Journal of Pediatric Urology in 2005. The SPU and the AAP Section on Urology came together to form the Pediatric Urology Advisory Council (PUAC) in 2000, which worked with the ABU to create subspecialty certification in pediatric urology with an independent exam, first administered in 2008 to 176 applicants. CONCLUSION: The metaphor "We have stood on the shoulders of giants" is apt for pediatric urology: Meredith Campbell, Frank Bicknell, David Innes Williams (Hospital for Sick Children, London), and J. Herbert Johnston (Alder Hay Hospital, Liverpool) come to mind among the first generation of pediatric urology pioneers, and others among their colleagues also had significant impact. Clearly this is a story of persistence and attention to detail on the part of those giants and those who followed. Pediatric urology became a distinct discipline after the SPU and AAP-SOU came together to create a robust cohort of pediatric urologists who through education and negotiation were able to help the ABU and the American Board of Medical Specialties (ABMS) recognize that subspecialization would lead to better care for children with urologic disorders. This benchmark set a high bar for future subspecialization in urology and other fields.
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Pediatrics , Urology , Urology/history , Pediatrics/history , United States , History, 20th Century , Humans , Societies, Medical/history , History, 21st CenturyABSTRACT
Introduction: We examined the history of the Endourological Society through the lens of its fellowship programs in the United States (U.S.). Methods: A review of the list of fellowship programs published annually in the Journal of Endourology from 1987 to 2015 allowed us to track the growth in fellowship programs over time. We reviewed the Endourological Society fellowship database and the websites for each of the fellowship programs for the names of graduates from each program. A survey was sent to each fellowship program director with a list of their graduates asking them to verify the names and to identify those graduates who had pursued a career in academic urology, and whether they had served as fellowship program director, residency program director or department chairperson. Seventeen of the 52 U.S. program directors (33%) responded to the survey. For those programs that did not respond to the survey each graduate's name was searched via Google, LinkedIn, and/or Doximity to determine if they had pursued a career in academic urology and served in a leadership position. Results: The number of U.S. Endourological Society fellowships has increased from 11 in 1987 to 52 in 2021. Five hundred and seventy-seven fellows have graduated from an Endourological Society Fellowship in the United States from 1987 to 2021. Two hundred and fifty fellows have pursued a career in academic urology (43.3%), 46 have served as fellowship program director (8.0%), 9 as residency program director (1.6%), and 13 have served as department chairperson (2.3%). Conclusions: The progress of the Endourological Society can be directly tied to the historical growth of its fellowship programs and the pursuit of an academic career by many of its graduates leading them to become the current and future educational leaders in the field.
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Fellowships and Scholarships , Internship and Residency , United States , Humans , Surveys and Questionnaires , Education, Medical, GraduateABSTRACT
OBJECTIVE: To explore and document the life and urologic contributions of Dr. Frank B. Bicknell. METHODS: We researched the life of Dr. Bicknell via his publications, archived documents from the Didusch Museum and through the description of his life and accomplishments by his colleagues including John K. Lattimer and Frank Hinman Jr. RESULTS: Frank B. Bicknell (1907-1999) attended the University of Michigan (1925-1928) and Universityof Michigan Medical School (1928-1932) prior to his internship and urology residency at the Receiving Hospital, Detroit, Michigan (1932-1936). He served in the Merchant Marine in the 1930s, sailing around the world. He was a major in World War II and served as Professor of Urology at Wayne State University. In 1951 Dr. Bicknell got together a small group of eight urologists interested in pediatric urology during the AUA Annual Meeting. Drs. Campbell, Barber, Johnson, Mertz, Hinman Jr., Spence and Lattimer all met in Dr. Bicknell's Chicago hotel room and would form The Society for Pediatric Urology. At the time, Dr. Bicknell's brother-in-law had just become president of the American Academy of Pediatrics (AAP). Dr. John Lattimer with the help of Dr. Bicknell's brother-in-law was able to get a room at the AAP meeting which he filled with 2500 people, thought to be the largest collection of urologists in one room at the time. The success of the session led the AAP to develop a Section of Urology and impressed upon the AUA the magnitude of interest in pediatric urology. This allowed pediatric urologists to secure an exclusive session on the day before the main AUA meeting which has persisted since that time.Dr. Bicknell founded the History Forum in 1966 and chaired this very popular event during its first decade. The forum now occupies an entire afternoon during the AUA annual meeting, with papers presented on historic urologic topics. The highlight of this assembly is the annual lecture on the history of medicine. In 2000, this oration was renamed the Frank Bicknell History of Urology Oration to honor the founder of the History Forum. CONCLUSION: Dr. Frank Bicknell was an early leader in pediatric urology and urologic history who helped found The Society of Pediatric Urology and the AUA History Forum.
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Pediatrics , Urology , Humans , Male , History, 20th Century , Hospitals , Michigan , United States , Urologists , Urology/history , World War II , Congresses as Topic/history , Pediatrics/history , Societies, Medical/historyABSTRACT
INTRODUCTION: Philipp Bozzini, a German army surgeon, in 1807 invented the Lichtleiter, the predecessor of the modern cystoscope. By the mid-1800s, several new instruments were created including one, a variation on Bozzini's instrument by Antoine Desormeaux in Paris. The William P. Didusch Museum of Urologic History acquired the Wales endoscope, a rare and unique cystoscope that was invented around the same time in the United States. METHODS: We researched the life of Philip Wales and the description of his cystoscope as well as Horatio Kern, the instrument maker that produced Wales' instrument. We examined the Wales cystoscope acquired by the William P. Didusch Museum. RESULTS: Philip Skinner Wales (1837-1906) was a surgeon who entered the United States Navy in 1856 and served throughout the Civil War. He organized and held charge of the Naval Hospital at New Orleans during the operations of Admiral Farragut's fleet in the Mississippi River. He was one of the first surgeons to attend President Garfield when he was shot. He was Surgeon General of the Navy (1879-1884) and founded the Museum of Naval Hygiene in Washington D.C. which later, combined with the naval laboratory and Department of Instruction, became the prototype of the Naval Medical School. In 1868 he published a series of papers in the Philadelphia Medical and Surgical Reporter on "Instrumental Diagnosis," with a paper entitled "Description of a New Endoscope." The instrument contained a metal shaft with an acute beak and used an ophthalmologic mirror to reflect light down the channel. The surgeon peered through the center hole to look into the bladder. Wales used his instrument multiple times in his private practice. Wales writes that the advantages of his cystoscope were that it was simple to produce and cheap compared to Desormeaux's endoscope. Furthermore it was light, weighing approximately 2 pounds. The main drawbacks of Wales' cystoscope were the inadequate illumination, as the light source was external and projected from the outside through a narrow channel into the bladder, and that without an optical system the image appeared relatively small. Horatio Kern, a well-known instrument maker in Philadelphia, that also supplied surgical sets and instruments for the U.S. Army during the Civil War, produced Wales' cystoscope. While he was Chief of the Bureau of Medicine, a subordinate embezzled Navy funds and Dr, Wales was court-martialed. Though he was eventually exonerated, he lived the rest of his life in disgrace in France. CONCLUSION: The Wales endoscope is unique in that it had an American inventor, was simple in design and cheap to produce. It is an important historical artifact and is one of the earliest and rarest cystoscopes developed.
Subject(s)
Cystoscopes , Military Personnel , United States , Humans , Wales , Endoscopes , Military Personnel/history , FranceSubject(s)
Infection Control/history , Masks/history , Respiratory Tract Infections/history , Europe , History, 15th Century , History, 16th Century , History, 17th Century , History, 18th Century , History, 19th Century , History, 20th Century , History, 21st Century , History, Medieval , Humans , Pandemics/history , Plague/history , Respiratory Tract Infections/prevention & control , United StatesABSTRACT
INTRODUCTION: The development of renal stones in space would not only impact the health of an astronaut but could critically affect the success of the mission. MATERIALS AND METHODS: We reviewed the medical literature, texts and multimedia sources regarding the careers of Dr. Abraham Cockett and Dr. Peggy Whitson and their contributions to the study of urolithiasis in space, as well as the studies in between both of their careers that helped to further characterize the risks of stone formation in space. RESULTS: Dr. Abraham T. K. Cockett (1928-2011) was Professor and Chair of the Department of Urology at the University of Rochester and served as AUA President (1994-1995). In 1962, Dr. Cockett was one of the first to raise a concern regarding astronauts potentially forming renal stones in space and suggested multiple prophylactic measures to prevent stone formation. Many of the early studies in this field used immobilized patients as a surrogate to a micro-gravity environment to mimic the bone demineralization that could occur in space in order to measure changes in urinary parameters. Dr. Peggy A. Whitson (1960-), is a biochemistry researcher and former NASA astronaut. She carried out multiple studies examining renal stone risk during short term space shuttle flights and later during long-duration Shuttle-Mir missions. CONCLUSION: From the early vision of Dr. Cockett to the astronaut studies of Dr. Whitson, we have a better understanding of the risks of urolithiasis in space, resulting in preventive measures for urolithiasis in future long duration space exploration.
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Kidney Calculi/history , Space Flight/history , History, 20th Century , History, 21st Century , Humans , Kidney Calculi/etiology , Kidney Calculi/prevention & controlSubject(s)
Physicians, Women/history , Urology/history , History, 20th Century , Humans , Physician's Role , United States , Urology/educationABSTRACT
Animal models are useful in the study of many human diseases. Our current understanding of the biological, physiological, and biochemical aspects of hyperoxaluria and calcium oxalate urolithiasis has been greatly informed by studies using animals. Recently, limitations in the extrapolation to humans of research results derived from laboratory rodents have been identified. The use in biomedical research of a variety of organisms, including large animals, is increasingly encouraged. The purpose of this article is to review the use of pigs in biomedical and stone research, to provide a rationale for using pigs in metabolic stone research, and to describe our 8-year experience in developing a porcine platform for studying hyperoxaluria and calcium oxalate urolithiasis. In this article, we share and review some of the highlights of our findings. We also report results from a recent feeding swine study that demonstrated oxalate-induced renal nephropathy. Finally, we offer ideas for future directions in urolithiasis research using swine.
Subject(s)
Calcium Oxalate , Kidney Calculi/etiology , Animals , Biomedical Research , Disease Models, Animal , Humans , Kidney Calculi/chemistry , SwineABSTRACT
INTRODUCTION: Serendipity, innovative physicians, evolving techniques for renal access, and improvements in equipment and radiology led to the evolution of percutaneous nephrolithotomy (PCNL). METHODS: We searched urology texts and the literature for sources pertaining to the history and development of PCNL. RESULTS: In 1941, Rupel and Brown performed the first nephroscopy when a rigid cystoscope was passed into the kidney following open surgery. Willard Goodwin, in 1955, while trying to perform a renal arteriogram, placed a needle into the collecting system of a hydronephrotic kidney and performed the first antegrade nephrostogram. He left a tube to drain the kidney, thereby placing the first nephrostomy tube. By 1976, Fernström and Johansson were the first to describe a technique for extracting renal calculi through a percutaneous nephrostomy under radiological control. In 1978, Arthur Smith, would describe the first antegrade stent placement when he introduced a Gibbons stent through a percutaneous nephrostomy in a patient with a reimplanted ureter. Dr. Smith would coin the term "endourology" to describe closed, controlled manipulation of the genitourinary tract. His collaboration with Kurt Amplatz, an interventional radiologist and medical inventor, would lead to numerous innovations that would further advance PCNL. In the 1980s the process of renal access and tract dilation was improved upon and the use of a rigid cystoscope was replaced by offset nephroscopes with a large straight working channel. Radiographic innovations, including improvements in fluoroscopy would further aid in renal access. The development of various lithotripsy devices and the introduction of the holmium laser improved the efficiency of stone fragmentation and clearance. The increased clinical experience and utilization of PCNL would lead to the characterization of stone-free rates and complications for the procedure. CONCLUSION: Serendipity, innovations in renal access, optics, radiology, and improvements in lithotripsy all contributed to the modern day PCNL.
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Endoscopy/history , Kidney Calculi/surgery , Kidney/surgery , Lithotripsy/history , Nephrostomy, Percutaneous/history , Urology/history , Endoscopy/instrumentation , History, 20th Century , Humans , Kidney Calculi/diagnosis , Kidney Diseases/diagnosis , Kidney Diseases/surgery , Lithotripsy/instrumentation , Lithotripsy, Laser/history , Lithotripsy, Laser/instrumentation , Nephrostomy, Percutaneous/instrumentationSubject(s)
Forensic Ballistics/history , History , Urology/history , History, 20th Century , History, 21st Century , MichiganABSTRACT
BACKGROUND AND OBJECTIVES: To evaluate the effect of operative time on the risk of symptomatic venous thromboembolic events (VTEs) in patients undergoing robot-assisted radical prostatectomy (RARP). METHODS: We reviewed the records of all patients at our institution who underwent RARP by a single surgeon from January 2007 until April 2011. Clinical and pathologic information and VTE incidence were recorded for each patient and analyzed by use of logistic regression to evaluate for association with VTE risk. All patients had mechanical prophylaxis, and beginning in February 2008, a single dose of unfractionated heparin, 5000 U, was administered before surgery. RESULTS: A total of 549 consecutive patients were identified, with a median follow-up period of 8 months. During the initial 30 days postoperatively, 10 patients (1.8%) had a VTE (deep venous thrombosis in 7 and pulmonary embolism in 3). The median operative time was 177 minutes (range, 121-360 minutes). An increase in operative time of 30 or 60 minutes was associated with 1.6 and 2.8 times increased VTE risks. A 5-point increase in body mass index and need for blood transfusion were also associated with increased risk of VTEs (odds ratios of 2.0 and 11.8, respectively). Heparin prophylaxis was not associated with a significant VTE risk reduction but also was not associated with a significant increase in estimated blood loss (P = .23) or transfusion rate (P = .37). CONCLUSION: A prolonged operative time increases the risk of symptomatic VTEs after RARP. Future studies are needed to evaluate the best VTE prophylactic approach in patients at risk.
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Postoperative Complications/epidemiology , Prostatectomy/adverse effects , Pulmonary Embolism/etiology , Robotics , Venous Thrombosis/etiology , Adult , Aged , Female , Humans , Incidence , Male , Middle Aged , Odds Ratio , Operative Time , Prostatectomy/methods , Pulmonary Embolism/epidemiology , Time Factors , United States/epidemiology , Venous Thrombosis/epidemiologyABSTRACT
OBJECTIVES: Given the high recurrence rate of cystine urolithiasis, understanding of the radiographic stone characteristics is important in following cystine stone formers over their lifetime. However, due to their infrequent incidence, in vivo radiographic properties of cystine stones have not been well characterized. The purpose of our study is to characterize the in vivo radiographic properties of cystine urolithiasis. METHODS: Patients with a cystine stone analysis and noncontrast computed tomography (NCCT) were extracted from our stone clinic database. Stone attenuation in Hounsfield units (HU) was measured for each stone and plain abdominal films (kidney, ureter, and bladder radiograph [KUB]) within 30 days of the NCCT prior to any intervention were reviewed by a blinded radiologist to assess whether urolithiasis could be visualized. RESULTS: Twenty patients met our study inclusion criteria. When plotted by attenuation, two distinct groups of stone attenuation were noted for cystine stone formers (p<0.001). The largest group (n=16) had an attenuation of <550 HU (424±106 HU), while a distinct second group (n=4) was >850 HU (972±134 HU). Sixteen patients had a KUB, with 88% of the stones being visualized by a blinded radiologist. Stone size and attenuation were not significantly different between visualized and nonvisualized stones via KUB, however, the body mass index was significantly higher in the nonvisualized group (34.4 vs 26.9 kg/m(2), p=0.03). CONCLUSIONS: Cystine stones were visualized by KUB, which has implications in post-treatment follow-up imaging. Though most cystine stones had an attenuation of <550 HU, a second distinct group of cystine stones were noted to have a high attenuation of >850 HU. HU measurements alone are not sufficient to differentiate cystine stones from other stone compositions.
Subject(s)
Cystine , Kidney Calculi/diagnostic imaging , Ureteral Calculi/diagnostic imaging , Urinary Bladder Calculi/diagnostic imaging , Adult , Aged , Female , Humans , Kidney Calculi/chemistry , Male , Middle Aged , Tomography, X-Ray Computed/methods , Ureteral Calculi/chemistry , Urinary Bladder Calculi/chemistry , Young AdultABSTRACT
PURPOSE: We aimed to determine the current practice patterns at academic institutions in the use of ablative technologies for the management of small renal masses. PATIENTS AND METHODS: Mail surveys were sent to 124 academic institutions in the United States. The survey consisted of 12 questions pertaining to institutional demographic information, the use of ablation technology for small renal masses, the role of the urologist in ablation, and biopsy preferences prior to treatment. RESULTS: The overall response rate was 52% (64/124). Ablation was offered by all of the academic centers that responded to the survey and included 73% percutaneous cryoablation, 52% percutaneous radiofrequency ablation, 83% laparoscopic cryoablation, and 20% laparoscopic radiofrequency ablation. Eighty-eight percent of institutions performed one to five total ablation procedures each month. Urologists alone performed 13% of ablation procedures, radiologists performed 45% of ablation procedures, and a combined approach (urologist and radiologist present) was used in 43% of the institutions. When questioned about their role during percutaneous ablation, we found that urologists were present at the time of ablation in 59% of institutions, in 32% of institutions urologists placed the needles for ablation, and in 98% of institutions urologists were responsible for the postoperative care of the patient. Eighty-nine percent of academic institutions performed a biopsy of the renal mass with 67% performing a core biopsy, 5% performing a fine-needle aspiration (FNA), and 28% performing both a core biopsy and FNA. Nineteen percent of institutions performed a renal mass biopsy prior to the day of the procedure so that the pathology was known prior to ablation. CONCLUSIONS: Ablative technologies are well utilized for the treatment of small renal masses at current academic institutions with urologists directly involved in the ablation procedure in only half of the institutions. While preablation biopsy is common, pathology is rarely known prior to ablation.
Subject(s)
Academic Medical Centers/statistics & numerical data , Academies and Institutes/statistics & numerical data , Catheter Ablation/methods , Kidney Neoplasms/epidemiology , Kidney Neoplasms/surgery , Practice Patterns, Physicians'/statistics & numerical data , Health Care Surveys/statistics & numerical data , Humans , United States/epidemiologyABSTRACT
BACKGROUND AND PURPOSE: Surgical management of a renal neoplasm in a solitary kidney is a balance between oncologic control and preservation of renal function. We analyzed patients with a renal mass in a solitary kidney undergoing nephron-sparing procedures to determine perioperative, oncologic, and renal functional outcomes. PATIENTS AND METHODS: A multicenter study was performed from 12 institutions. All patients with a functional or anatomic solitary kidney who underwent nephron-sparing surgery for one or more renal masses were included. Tumor size, complications, and recurrence rates were recorded. Renal function was assessed with serum creatinine level and estimated glomerular filtration rate. RESULTS: Ninety-eight patients underwent 105 ablations, and 100 patients underwent partial nephrectomy (PN). Preoperative estimated glomerular filtration rate (eGFR) was similar between the groups. Tumors managed with PN were significantly larger than those managed with ablation (P<0.001). Ablations were associated with a lower overall complication rate (9.5% vs 24%, P=0.01) and higher local recurrence rate (6.7% vs 3%, P=0.04). Eighty-four patients had a preoperative eGFR ≥60 mL/min/1.73 m(2). Among these patients, 19 (23%) fell below this threshold after 3 months and 15 (18%) at 12 months. Postoperatively, there was no significant difference in eGFR between the groups. CONCLUSIONS: Extirpation and ablation are both reasonable options for treatment. Ablation is more minimally invasive, albeit with higher recurrence rates compared with PN. Postoperative renal function is similar in both groups and is not affected by surgical approach.