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1.
Leg Med (Tokyo) ; 15(5): 256-9, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23602209

ABSTRACT

We present a case of a ruptured abdominal aortic aneurysm (AAA) with ambiguous accessory findings on post-mortem computed-tomography (PMCT), post-mortem magnetic resonance (PMMR) imaging, and PMCT-angiography (PMCTA) suggestive of thoracic aortic dissection. The diagnosis of ruptured AAA was confirmed by autopsy; however, there was no aortic dissection. The imaging findings that mimicked the presence of aortic dissection might have been an atypical presentation of post-mortem clotting or sedimentation. This case is an ideal example to illustrate benefits, limitations, and challenges of post-mortem cross-sectional imaging. It serves as a reminder that both, training as well as correlation of imaging findings with autopsy are fundamental to improve our understanding of radiologic findings on post-mortem cross-sectional imaging.


Subject(s)
Aorta, Thoracic/pathology , Aortic Aneurysm, Abdominal/pathology , Aortic Aneurysm, Thoracic/pathology , Aortic Dissection/pathology , Diagnostic Imaging/methods , Forensic Pathology/methods , Plaque, Atherosclerotic/diagnostic imaging , Aged , Aortic Dissection/diagnostic imaging , Angiography , Aorta, Thoracic/diagnostic imaging , Aortic Aneurysm, Abdominal/diagnostic imaging , Aortic Aneurysm, Thoracic/diagnostic imaging , Aortic Rupture/diagnostic imaging , Aortic Rupture/pathology , Autopsy , Diagnosis, Differential , Humans , Magnetic Resonance Imaging , Male , Plaque, Atherosclerotic/pathology , Tomography, X-Ray Computed
2.
Leg Med (Tokyo) ; 11(5): 229-33, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19520596

ABSTRACT

A 52-year-old man was found dead in his bed. He had financial and psychosocial problems like separation from his wife and children or unemployment due to alcoholism. Under treatment of disulfiram he was presently abstinent from alcohol. As he had suffered from epileptic seizures and dizziness, he received valproic acid and the vasodilator naftidrofuryl, respectively. Autopsy showed no morphologic cause of death. Chemical analysis of blood revealed concentrations for valproic acid and disulfiram in the therapeutic and above the therapeutic range but far below the lethal level, respectively. No ethanol was found. However, the very high concentration of 7500 microg/L naftidrofuryl in whole blood was considered as cause of death, and the most probable manner of death seemed to be suicide. To our knowledge, this is the first reported case of a fatal poisoning with naftidrofuryl.


Subject(s)
Nafronyl/poisoning , Suicide , Vasodilator Agents/poisoning , Alcohol Deterrents/blood , Anti-Inflammatory Agents, Non-Steroidal/analysis , Anticonvulsants/blood , Disulfiram/blood , Forensic Toxicology , Gas Chromatography-Mass Spectrometry , Gastrointestinal Contents/chemistry , Humans , Male , Mefenamic Acid/analysis , Middle Aged , Nafronyl/analysis , Valproic Acid/blood , Vasodilator Agents/analysis
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