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J Pediatr ; 173: 245-249.e4, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27079964

ABSTRACT

UNLABELLED: Biomarkers may be helpful in prediction of outcomes of infants with congenital diaphragmatic hernia. The predictive value of high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide was investigated in 128 infants with congenital diaphragmatic hernia. After correction for multiple testing, those biomarkers did not predict severe pulmonary hypertension, death, need of extracorporeal membrane oxygenation, or bronchopulmonary dysplasia. TRIAL REGISTRATION: Netherlands Trial Registry: 1310.


Subject(s)
Hernias, Diaphragmatic, Congenital/mortality , Natriuretic Peptide, Brain/blood , Troponin T/blood , Biomarkers/blood , Bronchopulmonary Dysplasia/epidemiology , Extracorporeal Membrane Oxygenation/statistics & numerical data , Female , Hernias, Diaphragmatic, Congenital/surgery , Humans , Hypertension, Pulmonary/epidemiology , Infant, Newborn , Male , Netherlands/epidemiology , Prognosis , Prospective Studies , Severity of Illness Index
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