Neoplasia de ducto nasolacrimal em uma cadela / Nasolacrimal duct neoplasm in a bitch

Background: Nasolacrimal duct tumors are divided into primary and secondary, with primary tumors being rare in all species. Secondary involvement of the lacrimal sac and duct can occur from any skin lesion involving the eyelid and/or conjunctiva and from any neoplastic process involving the paranasal sinuses. Lacrimal sac metastatic lesions may originate from any distant site and include carcinomas or melanomas, with squamous cell carcinoma being the most common type. The objectives of the present report were to describe a case of squamous cell carcinoma in the nasolacrimal duct and to emphasize the importance of a good ophthalmic evaluation. Case: A 16-year-old spayed bitch white poodle was presented to the veterinary clinic. The owner complained that the animal had epiphora and mucoid secretion in the right eye, eyelid hyperemia in both eyes, and sporadic sneezing with blood. On ophthalmic examination, the animal was initially diagnosed with nasolacrimal duct obstruction and right eye (OD) blepharitis and OU uveitis. Fourteen days after the first evaluation, the nasolacrimal duct region increased, with the presence of bloody secretion. Biomicroscopy showed nodules inside the lacrimal duct, in the punctum region. The animal was sedated to obtain a fragment of the nodule for histopathological analysis, and a subsequent oral cavity evaluation identified a nodule in the transition region between the 4th premolar and 1st molar, which was sent for cytology. Cytology of the medial corner region of the RE showed epithelial and mesenchymal cells with malignancy characteristics, and the biopsy was suggestive of malignant epithelial neoplasia (carcinoma). A surgical procedure for nodule resection was ruled out because bone involvement was extensive, and chemotherapy was selected. The patient died 2 months after the 1st consultation. The diagnosis was confirmed through necropsy via immunohistochemical tests, demonstrating squamous cell carcinoma (SCC) both in the mouth and the nasal and ocular sinuses. Discussion: The most common conditions affecting the nasolacrimal drainage system in dogs are those causing obstructions. These may be congenital, arising from a developmental defect of micropunctum or agenesis of the punctum, they may be acquired, arising from infection and inflammation. SCC is a malignant neoplasm originating in the stratified squamous epithelium. The predisposing factors in cats and dogs include lack of adnexal pigmentation and, possibly, chronic irritation of the ocular surface. A light coat is considered a relevant factor, especially in regions with little hair coverage. In addition to a mass lesion, other clinical signs of eyelid or ocular surface tumors may include epiphora, conjunctival vascular injection, mucopurulent ocular discharge, 3rd eyelid protrusion, conjunctival/corneal roughness or ulceration, and corneal neovascularization or pigmentation. Clinical presentations are nonspecific. Neoplasms, whether nasal and/or in the maxillary sinus, can invade the nasolacrimal duct and spread to the nasal cavity, and neoplasms in the nasal cavity can invade the nasolacrimal duct. Ophthalmic evaluation along with good inspection of the oral cavity is a useful tool in the diagnosis of eye neoplasms that may have effects on the oral cavity or vice versa due to the strong association between them. Early diagnosis is crucial for the clinical or surgical management of each case of ophthalmic neoplasia and for therapeutic success.

Mielolipoma de adrenal funcional em um cão / Functional adrenal myelolipoma in a dog

Background: Myelolipomas are benign tumors composed of a mixture of fat and hematopoietic tissue similar to the bone marrow. They are rare tumors in humans and dogs, and occur generally in the spleen, liver, spinal canal and in the adrenal glands. When they develop in the adrenal glands they feature non-secretory and endocrinologically inactive characteristics, usually without clinical signs or other dysfunctions. Thus, they are often an incidental finding during necropsy. This paper aims to describe a case of functional adrenal gland myelolipoma and spleen myelolipoma in a female dog with clinical signs and laboratory tests compatible with hyperadrenocorticism.Case: A 12 year-old female dog, undefined breed, was treated at the Hospital Unit for Companion Animals of the Pontifical Catholic University of Paraná (PUCPR), São José dos Pinhais, Paraná, Brazil, with polyuria, polydipsia, polyphagia, cutaneous hypotonia and central obesity. Blood tests showed hypercholesterolemia and increased alkaline phosphatase; urinalysis identified isostenuria with proteinuria; and ultrasound and MRI of the abdomen indicated right adrenomegaly, with heterogeneous characteristics, without invasion of attached blood vessels and splenic nodules. The low dose dexamethasone suppression test was performed which confirmed hyperadrenocorticism. The animal was submitted to adrenalectomy and splenectomy, and tissue specimens were obtained for histopathological examination, which revealed mature adipocytes and hematopoietic elements in different phases of maturation, compatible with adrenal and spleen myelolipoma. After surgical treatment, there was a progressive improvement of the clinical manifestations and laboratory abnormalities of hypercortisolemia, without recurrence during one year.[...]

Mielolipoma de adrenal funcional em um cão / Functional adrenal myelolipoma in a dog

Background: Myelolipomas are benign tumors composed of a mixture of fat and hematopoietic tissue similar to the bone marrow. They are rare tumors in humans and dogs, and occur generally in the spleen, liver, spinal canal and in the adrenal glands. When they develop in the adrenal glands they feature non-secretory and endocrinologically inactive characteristics, usually without clinical signs or other dysfunctions. Thus, they are often an incidental finding during necropsy. This paper aims to describe a case of functional adrenal gland myelolipoma and spleen myelolipoma in a female dog with clinical signs and laboratory tests compatible with hyperadrenocorticism.Case: A 12 year-old female dog, undefined breed, was treated at the Hospital Unit for Companion Animals of the Pontifical Catholic University of Paraná (PUCPR), São José dos Pinhais, Paraná, Brazil, with polyuria, polydipsia, polyphagia, cutaneous hypotonia and central obesity. Blood tests showed hypercholesterolemia and increased alkaline phosphatase; urinalysis identified isostenuria with proteinuria; and ultrasound and MRI of the abdomen indicated right adrenomegaly, with heterogeneous characteristics, without invasion of attached blood vessels and splenic nodules. The low dose dexamethasone suppression test was performed which confirmed hyperadrenocorticism. The animal was submitted to adrenalectomy and splenectomy, and tissue specimens were obtained for histopathological examination, which revealed mature adipocytes and hematopoietic elements in different phases of maturation, compatible with adrenal and spleen myelolipoma. After surgical treatment, there was a progressive improvement of the clinical manifestations and laboratory abnormalities of hypercortisolemia, without recurrence during one year.[...](AU)

Immediate postoperative evaluation of enteric anastomosis after the use of meloxicam in rats

PURPOSE: To compare ileal anastomoses in the immediate postoperative healing period after meloxicam use. METHODS: Forty two male Wistar rats were randomly divided into two groups of 21, COX and control group. To COX meloxicam in combination with morphine was given in 3 days period. Control group received only morphine during the same period. Each group was divided into three sub-groups of 7, which were euthanized at 5, 10, and 21 days postoperatively. Comparison was based in histological evaluation of collagen type I and III using sirius red, immunohistochemical through vascular endothelial growth factor and matrix metalloproteinase-9. RESULTS: Healing process in scheduled periods did not show significant differences (p>0.05) between the COX and control groups during any of the periods. CONCLUSION: The use of meloxicam in the postoperative period following ileal anastomosis did not affect healing.

Immediate postoperative evaluation of enteric anastomosis after the use of meloxicam in rats

ABSTRACT PURPOSE : To compare ileal anastomoses in the immediate postoperative healing period after meloxicam use. METHODS: Forty two male Wistar rats were randomly divided into two groups of 21, COX and control group. To COX meloxicam in combination with morphine was given in 3 days period. Control group received only morphine during the same period. Each group was divided into three sub-groups of 7, which were euthanized at 5, 10, and 21 days postoperatively. Comparison was based in histological evaluation of collagen type I and III using sirius red, immunohistochemical through vascular endothelial growth factor and matrix metalloproteinase-9. RESULTS: Healing process in scheduled periods did not show significant differences (p>0.05) between the COX and control groups during any of the periods. CONCLUSION: The use of meloxicam in the postoperative period following ileal anastomosis did not affect healing.

Immediate postoperative evaluation of enteric anastomosis after the use of meloxicam in rats

PURPOSE :To compare ileal anastomoses in the immediate postoperative healing period after meloxicam use.METHODS:Forty two male Wistar rats were randomly divided into two groups of 21, COX and control group. To COX meloxicam in combination with morphine was given in 3 days period. Control group received only morphine during the same period. Each group was divided into three sub-groups of 7, which were euthanized at 5, 10, and 21 days postoperatively. Comparison was based in histological evaluation of collagen type I and III using sirius red, immunohistochemical through vascular endothelial growth factor and matrix metalloproteinase-9.RESULTS:Healing process in scheduled periods did not show significant differences (p>0.05) between the COX and control groups during any of the periods.CONCLUSION:The use of meloxicam in the postoperative period following ileal anastomosis did not affect healing.(AU)

Responsible pet ownership perception in elementary schools after an educational program in Southern Brazil / Percepção dos alunos de ensino fundamental sobre guarda responsável de animais após um programa de educação no sul do Brasil

The impact of responsible ownership programs with the goal of promoting public health remains to be fully established in Brazil. This study aimed to evaluate the responsible pet ownership perception of public elementary school students and teachers after a four-year outreach educational program in the city of Pinhais, Southern Brazil. Questionnaires were distributed for self-answer by fourth-grade students and teachers of all city public elementary schools. A total of 1,022/1,332 students (76.7%) referred participated in the program. No significant differences were observed between participating and non-participating groups regarding the concepts of responsible ownership (p = 0.88), zoonoses (p = 0.09) and animal welfare (p = 0.94). However, the frequency of correct answers on responsible ownership and zoonoses concepts was significantly higher (p 0.01) among student groups who participated 1 or 2 times (779/830; 93.8% and 506/813; 62.2%, respectively) in relation to the groups that participated > 2 times (144/165; 87.3% and 64/151; 42.4%, respectively). It was also significantly higher (p 0.01) between 10 years group (991/1058, 93.7%) compared to group >10 years (158/180; 87.8%) in the first concept. Although most teachers approved the continuing program (128/137; 93.4%), they reported low rates on training participation (41/137; 29.9%) and use of available teaching materials (78/137; 26.9%). The study has shown that perception of responsible pet ownership in outreach education programs may be more easily absorbed by children under ten years of age and up to two participations(AU)

O impacto de programas de guarda responsável que objetivam promover a saúde pública precisa ser plenamente estabelecido no Brasil. Este estudo objetivou avaliar a percepção sobre guarda responsável de animais de estudantes do ensino fundamental e professores após um programa com quatro anos de duração na cidade de Pinhais. Questionários foram distribuídos para alunos da quarta série e professores de todas as escolas públicas de ensino fundamental da cidade. No total, 1022/1332 estudantes (76,7%) participaram do programa. Não houve diferença significativa entre os grupos que participaram e não participaram, em relação aos conceitos de guarda responsável (p = 0,88), zoonoses (p = 0,09) e bem-estar animal (p = 0,94). Entretanto, a frequência de acertos dos conceitos de guarda responsável e zoonoses foi significativamente maior (p 0,01) entre os estudantes do grupo que participou 1 ou 2 vezes (779/830; 93,8% e 506/813; 62,2%, respectivamente) com relação ao grupo que participou > 2 vezes (144/165; 87,3% e 64/151; 42,4%, respectivamente). E também foi significativamente maior (p 0,01) entre o grupo 10 anos (991/1058; 93.7%) com relação ao grupo > 10 anos (158/180; 87,8%) no primeiro conceito. Apesar da maioria dos professores aprovarem a continuidade do programa (128/137; 93,4%), eles reportaram baixas taxas de participação no treinamento (41/137; 29,9%) e utilização dos materiais didáticos disponíveis (78/137; 26,9%). O estudo mostrou que a percepção sobre guarda responsável de animais em programas de educação continuada pode ser mais facilmente absorvida por crianças de até 10 anos de idade e com até duas participações(AU)

Responsible pet ownership perception in elementary schools after an educational program in Southern Brazil / Percepção dos alunos de ensino fundamental sobre guarda responsável de animais após um programa de educação no sul do Brasil

The impact of responsible ownership programs with the goal of promoting public health remains to be fully established in Brazil. This study aimed to evaluate the responsible pet ownership perception of public elementary school students and teachers after a four-year outreach educational program in the city of Pinhais, Southern Brazil. Questionnaires were distributed for self-answer by fourth-grade students and teachers of all city public elementary schools. A total of 1,022/1,332 students (76.7%) referred participated in the program. No significant differences were observed between participating and non-participating groups regarding the concepts of responsible ownership (p = 0.88), zoonoses (p = 0.09) and animal welfare (p = 0.94). However, the frequency of correct answers on responsible ownership and zoonoses concepts was significantly higher (p 0.01) among student groups who participated 1 or 2 times (779/830; 93.8% and 506/813; 62.2%, respectively) in relation to the groups that participated > 2 times (144/165; 87.3% and 64/151; 42.4%, respectively). It was also significantly higher (p 0.01) between 10 years group (991/1058, 93.7%) compared to group >10 years (158/180; 87.8%) in the first concept. Although most teachers approved the continuing program (128/137; 93.4%), they reported low rates on training participation (41/137; 29.9%) and use of available teaching materials (78/137; 26.9%). The study has shown that perception of responsible pet ownership in outreach education programs may be more easily absorbed by children under ten years of age and up to two participations...

O impacto de programas de guarda responsável que objetivam promover a saúde pública precisa ser plenamente estabelecido no Brasil. Este estudo objetivou avaliar a percepção sobre guarda responsável de animais de estudantes do ensino fundamental e professores após um programa com quatro anos de duração na cidade de Pinhais. Questionários foram distribuídos para alunos da quarta série e professores de todas as escolas públicas de ensino fundamental da cidade. No total, 1022/1332 estudantes (76,7%) participaram do programa. Não houve diferença significativa entre os grupos que participaram e não participaram, em relação aos conceitos de guarda responsável (p = 0,88), zoonoses (p = 0,09) e bem-estar animal (p = 0,94). Entretanto, a frequência de acertos dos conceitos de guarda responsável e zoonoses foi significativamente maior (p 0,01) entre os estudantes do grupo que participou 1 ou 2 vezes (779/830; 93,8% e 506/813; 62,2%, respectivamente) com relação ao grupo que participou > 2 vezes (144/165; 87,3% e 64/151; 42,4%, respectivamente). E também foi significativamente maior (p 0,01) entre o grupo 10 anos (991/1058; 93.7%) com relação ao grupo > 10 anos (158/180; 87,8%) no primeiro conceito. Apesar da maioria dos professores aprovarem a continuidade do programa (128/137; 93,4%), eles reportaram baixas taxas de participação no treinamento (41/137; 29,9%) e utilização dos materiais didáticos disponíveis (78/137; 26,9%). O estudo mostrou que a percepção sobre guarda responsável de animais em programas de educação continuada pode ser mais facilmente absorvida por crianças de até 10 anos de idade e com até duas participações...

Transplante de glândulas salivares labiais no tratamento de olho seco em cães pela autoenxertia / Labial salivary glands transplantation in the treatment of dry eye in dogs by autograft

OBJETIVO: Avaliar os efeitos clínicos da secreção das glândulas salivares labiais como alternativa de lubrificação ocular para alívio do olho seco, em casos moderados, severos e refratários ao tratamento clínico, através da técnica de transposição de glândulas salivares labiais para o fórnice conjuntival pela autoenxertia. MÉTODOS: Foram selecionados 17 cães os quais apresentavam olho seco autoimune sem reposta satisfatória ao tratamento clínico. O teste lacrimal de Schirmer e o tempo de ruptura do filme lacrimal foram realizados no pré-operatório para avaliar a quantidade e a qualidade da lágrima produzida. Os pacientes foram submetidos aos exames oftálmicos completos no pré-operatório, a cada 15 dias por dois meses e a cada 30 dias por mais dois meses, totalizando seis retornos pós-operatórios. No pré-operatório e em todos os pós-operatórios fotografias digitais foram tiradas para o arquivo fotográfico. Utilizou-se o programa photoshop para avaliação e marcação dos neovasos corneanos em todos os retornos. RESULTADOS: Houve redução em todos os casos da secreção mucopurulenta, hiperemia conjuntival e blefarospasmo, bem como estabilização de lesões pré-existentes e redução importante do número de neovasos corneanos. A transposição resultou na melhora do tempo de ruptura do filme lacrimal, porém sem alterações significativas no teste de Schirmer. CONCLUSÃO: O transplante das glândulas salivares labiais para o fórnice conjuntival é um procedimento de fácil execução, rápido, eficaz, acessível a qualquer cirurgião veterinário oftalmologista e de grande valia para casos moderados e severos de ceratoconjuntivite seca não responsivos às medicações existentes.

OBJECTIVE: To evaluate the clinical effects of lips salivary gland secretion as ocular lubricant for dry eye relief in mild cases, severe and refractory to medical treatment, through the transposition technique of salivary glands autograft to the conjunctival fornix. METHODS: Seventeen dogs exhibiting autoimmune dry eye with no satisfactory response to clinical treatment were selected. Lacrimal Schirmer Test and Tear Film break-up time (BUT) preoperative tests were performed to estimate the quantity and the quality of produced tear. Animals were submitted to complete ophthalmic exams routine preoperative, each 15 days for two months and then each 30 days for more two months after surgery, totalizing six returns. Photos were taken before and after surgical procedure for photo archive. Photoshop software was utilized for corneal neovascular evaluation. RESULTS: Mucopurulent secretion, conjunctival hyperemia and blepharospasm diminished in all cases, as well as occurred stabilization of pre existent damages with important reduction of corneal neovascularization. The transposition resulted on break-up time tests improvement but no significant changes on Schirmer tests. CONCLUSION: This technique is simple, quick and effective, accessible to any veterinary ophthalmologist surgeon and is of great value for moderate and severe cases of dry keratoconjunctivitis not responsive to medications.

Síndrome paraneoplásica na medicina e na medicina veterinária– revisão / Paraneoplastic syndrome in medicine and veterinary medicine

Esta revisão tem como objetivo salientar os sistemas acometidos por síndromes paraneoplásicas e descreveras principais alterações associadas ao câncer. Para isso foram utilizadas fontes bibliográficas, livrose artigos de oncologia, nos quais se verificam informações comparativas entre o homem e a espécie canina,baseando-se apenas em síndromes paraneoplásicas verdadeiras. Com isso conclui-se que devidoao elevado custo dos exames complementares de triagem diagnóstica, a dificuldade diagnóstica paraneoplásicae o desconhecimento das alterações paraneoplásicas, pouco se sabe sobre esta síndrome e suaincidência, ocorrendo um falso negativo na casuística Hospitalar Veterinária. Logo, este assunto deve sercada vez mais estudado, a fim de esclarecer seus vieses.

This revision has as objective points out the systems attacked by paraneoplastic syndrome and to describethe main alterations associated to the cancer. For that bibliographical sources, books and articles ofoncology were used, us which comparative information are verified between the man and the canine species,just basing on true paraneoplastic syndromes. With that it is ended that due to the high cost of thecomplemental exams of selection diagnostic, the difficulty paraneoplastic diagnostic and the ignoranceof the paraneoplastic alterations, little it is known about this syndrome and her incidence, happening afalse negative in the casuistry Veterinary Hospitalar. Therefore, this subject should be studied more andmore, in order to explain their inclinations.

Síndrome paraneoplásica na medicina e na medicina veterináriarevisão / Paraneoplastic syndrome in medicine and veterinary medicine

Esta revisão tem como objetivo salientar os sistemas acometidos por síndromes paraneoplásicas e descreveras principais alterações associadas ao câncer. Para isso foram utilizadas fontes bibliográficas, livrose artigos de oncologia, nos quais se verificam informações comparativas entre o homem e a espécie canina,baseando-se apenas em síndromes paraneoplásicas verdadeiras. Com isso conclui-se que devidoao elevado custo dos exames complementares de triagem diagnóstica, a dificuldade diagnóstica paraneoplásicae o desconhecimento das alterações paraneoplásicas, pouco se sabe sobre esta síndrome e suaincidência, ocorrendo um falso negativo na casuística Hospitalar Veterinária. Logo, este assunto deve sercada vez mais estudado, a fim de esclarecer seus vieses.(AU)

This revision has as objective points out the systems attacked by paraneoplastic syndrome and to describethe main alterations associated to the cancer. For that bibliographical sources, books and articles ofoncology were used, us which comparative information are verified between the man and the canine species,just basing on true paraneoplastic syndromes. With that it is ended that due to the high cost of thecomplemental exams of selection diagnostic, the difficulty paraneoplastic diagnostic and the ignoranceof the paraneoplastic alterations, little it is known about this syndrome and her incidence, happening afalse negative in the casuistry Veterinary Hospitalar. Therefore, this subject should be studied more andmore, in order to explain their inclinations.(AU)

Effects of 3 topical plant extracts on wound healing in beef cattle.

Eleven heifers of the Purunã cattle breed were used to evaluate wound healing by second intention. An experimental wound excision model in bovines was created by means of a skin punch of diameter 2cm. The animals were topically treated for 17 days with a saline control or decoctions of Schinus terebinthifolius Raddi (Aroeira mansa), Tabebuia avellanedae Lorentz ex Griseb (Ipê Roxo), and Casearia sylvestris Sw.(Guaçatonga) mixed with carboxymethyl cellulose. Centripetal retraction, clinical, and histological aspects of the wounds were observed until complete healing. Decoctions of T. avellanedae and S. terebinthifolius, but not C. sylvestris, had a beneficial effect on wound healing by second intention.

Nasal septum resection due congenital thickness in foals / Ressecção de septo nasal devido ao espessamento congênito em potros

Nasal obstructions caused by nasal septal diseases are uncommon in horses and the main causes are malformations, mucosal lesions, neoplasias and trauma. The aim of this case report is to describe two cases of nasal obstruction in foals. Clinical signs were progressive with reduction of air flow bilaterally, intense respiratory noise and dyspnea. Endoscopy evaluation was not performed because, in both cases, it was not possible to introduce the probe into the nasal cavity due to bilateral stenosis. Radiographic exam confirmed nasal septum thickness. Both animals were submitted to septum resection surgery. In order to promote a better respiratory condition, tracheotomy was performed in both foals prior the surgery. The surgical technique applied was modified from DOYLE technique described previously (2005). Briefly, nasal bone trephine role was initially done in order to do osteotomy of its caudal portion. For osteotomy a modified osteotomy was used. The dorsal and ventral limits of the nasal bone were removed with a obstetric wire protected by metalical guide. After surgical recovery, in both cases, the clinical exam showed that the air flow was normal and without noise, allowing the foals to breathe normally. Tracheotomy healed by second intention. After eight months both foals breathed comfortably and they were suitable for physical activity. Histopathology evaluation did not

Obstruções nasais causadas por doenças do septo nasal são incomuns em cavalos e as principais causas são: malformações, lesões nas mucosas, neoplasias e trauma. O objetivo deste relato é descrever dois casos de obstrução nasal congênita em potros. Os sinais clínicos demonstravam redução progressiva do fluxo de ar bilateral, ruído respiratório e dispnéia intensa. Não foi possível realizar avaliação endoscópica pois em ambos os casos, não foi possível introduzir o equipamento na cavidade nasal devido à estenose bilateral. O exame radiográfico confirmou o aumento na espessura do septo nasal. Os animais foram submetidos à cirurgia de ressecção de septo. Para promover uma melhor condição respiratória a traqueostomia foi realizada nos dois potros antes da cirurgia. A técnica cirúrgica utilizada foi modificado da técnica descrita anteriormente DOYLE (2005). Inicialmente foi realizada a trepanação do osso nasal para osteotomia da porção caudal do septo, com auxilio de osteótomo modificado, sendo os limites dorsais e ventrais do septo removidos com uso de fio serra protegido por guias metálicos. Após a recuperação cirúrgica, nos dois casos, o exame clínico mostrou que o fluxo de ar estava normal e sem ruídos permitindo aos potros respirar normalmente. A traqueostomia cicatrizou por segunda intenção. Após oito meses os dois animais respiravam confortavelmente, estando aptos à atividade f

Dosagem de proteína C reativa em cadelas compiometra associada à SRIS/Sepse antes e apósadministração de Firocoxib (Previcox®) / Determination of C-reactive protein in bitches with SIRS/Sepsisassociated to pyometra before and after Firocoxib (Previcox®) treatment

A piometra é uma afecção de grande importância na clínica médica e cirúrgica de animais de companhia,podendo ocasionar graves efeitos deletérios, sobre tudo quando associada à Síndrome daResposta Inflamatória Sistêmica (SRIS). A proteína C reativa (PCR)é uma proteína de fase aguda,que aumenta em condições de danos teciduais, podendo ser útil na avaliação de pacientes em SRIS;em caso de resposta terapêutica favorável, seus valores diminuem de forma contínua. O uso de antiinflamatóriosesteroidais e não-esteroidais (AINE) tem sido pesquisado como ferramenta terapêuticana atenuação dos efeitos gerados pela SRIS. O AINE firocoxib apresenta mecanismo de ação baseadona inibição da cicloxigenase-2, não havendo estudos relacionando seu uso em cães sépticos. Essa pesquisaverificou a eficácia do firocoxib (Previcox®) na evolução da SRIS de 16 cadelas com piometrapor meio da dosagem de PCR e outros parâmetros laboratoriais. Os valores da PCR foram significativamentemenores nos animais submetidos ao tratamento com o firocoxib, sugerindo que o uso deanti-inflamatórios pode ser importante auxiliar na estabilização da paciente com piometra e no controleda resposta inflamatória sistêmica.

Pyometra is a disease of great importance in medicine and surgery of companion animals and cancause serious deleterious effects, especially when associated with systemic inflammatory responsesyndrome (SIRS). C-reactive protein (CRP) is an acute phase protein that increases in conditions oftissue damage and may be useful in evaluating patients with SIRS, in case of favorable therapeuticresponse, their values decrease continuously. The use of anti-inflammatory and non-steroidal drugs(NSAIDs) has been investigated as a therapeutic tool in mitigating the effects generated by SIRS. TheNSAID provides firocoxib mechanism of action based on the inhibition of cyclooxygenase-2, there areno studies linking its use in septic dogs. This research verified the effectiveness of firocoxib (Previcox®) in the evolution of SIRS, 16 bitches with pyometra by dosage PCR and other laboratory parameters.The values of CRP were significantly lower in animals subjected to treatment with firocoxib, suggestingthat the use of anti-inflammatory drugs may be important to assist in stabilizing the patient with pyometra and control of systemic inflammatory response.

Dosagem de proteína C reativa em cadelas compiometra associada à SRIS/Sepse antes e apósadministração de Firocoxib (Previcox®) / Determination of C-reactive protein in bitches with SIRS/Sepsisassociated to pyometra before and after Firocoxib (Previcox®) treatment

A piometra é uma afecção de grande importância na clínica médica e cirúrgica de animais de companhia,podendo ocasionar graves efeitos deletérios, sobre tudo quando associada à Síndrome daResposta Inflamatória Sistêmica (SRIS). A proteína C reativa (PCR)é uma proteína de fase aguda,que aumenta em condições de danos teciduais, podendo ser útil na avaliação de pacientes em SRIS;em caso de resposta terapêutica favorável, seus valores diminuem de forma contínua. O uso de antiinflamatóriosesteroidais e não-esteroidais (AINE) tem sido pesquisado como ferramenta terapêuticana atenuação dos efeitos gerados pela SRIS. O AINE firocoxib apresenta mecanismo de ação baseadona inibição da cicloxigenase-2, não havendo estudos relacionando seu uso em cães sépticos. Essa pesquisaverificou a eficácia do firocoxib (Previcox®) na evolução da SRIS de 16 cadelas com piometrapor meio da dosagem de PCR e outros parâmetros laboratoriais. Os valores da PCR foram significativamentemenores nos animais submetidos ao tratamento com o firocoxib, sugerindo que o uso deanti-inflamatórios pode ser importante auxiliar na estabilização da paciente com piometra e no controleda resposta inflamatória sistêmica.(AU)

Pyometra is a disease of great importance in medicine and surgery of companion animals and cancause serious deleterious effects, especially when associated with systemic inflammatory responsesyndrome (SIRS). C-reactive protein (CRP) is an acute phase protein that increases in conditions oftissue damage and may be useful in evaluating patients with SIRS, in case of favorable therapeuticresponse, their values decrease continuously. The use of anti-inflammatory and non-steroidal drugs(NSAIDs) has been investigated as a therapeutic tool in mitigating the effects generated by SIRS. TheNSAID provides firocoxib mechanism of action based on the inhibition of cyclooxygenase-2, there areno studies linking its use in septic dogs. This research verified the effectiveness of firocoxib (Previcox®) in the evolution of SIRS, 16 bitches with pyometra by dosage PCR and other laboratory parameters.The values of CRP were significantly lower in animals subjected to treatment with firocoxib, suggestingthat the use of anti-inflammatory drugs may be important to assist in stabilizing the patient with pyometra and control of systemic inflammatory response.(AU)

Revisão de literatura: Sequestro corneano felino / Literature Review: Feline Corneal Sequestrum

O seqüestro corneano é descrito na literatura desde 1964, sendo considerada uma afecção corneanaúnica de gatos, principalmente braquicefálicos. Relatos recentes descreveram este problema em cavaloe cão. Caracteriza-se, clinicamente, por uma placa marrom a preta, ovalada, de posição central ouparacentral na córnea e que provoca, dentre outros sinais, blefaroespasmo, fotofobia, epífora e hiperemiaconjuntival. Não há predisposição sexual e etária. A etiologia ainda não está definida, sendo aagressão crônica à córnea, infecção pelo herpesvirus felino tipo 1 (FHV-1) e anormalidades do filmelacrimal algumas das hipóteses. O tratamento baseia-se no grau de desconforto ocular, podendo serconservativo ou cirúrgico, mas este último ainda tem sido a melhor opção. Este trabalho tem por objetivofazer uma breve revisão de literatura sobre o seqüestro corneano felino, ressaltando seus sinaisclínicos, possíveis etiologias e tratamento

The corneal sequestration is described in the literature since 1964, and it is considered a corneal diseaseunique of cats, especially the brachycephalic breeds. Recent reports have described this problemin horse and dog. It is clinically characterized by a brown to black - oval shaped crust which positioncan be in the central or paracentral area of the cornea and causes, among other signs, blepharospasm,photophobia, epiphora and conjunctival hyperemia. There is no sexual or age predisposition. Theetiology is not defined yet, and the chronical aggression to cornea, feline herpesvirus type 1 (FHV-1)infection and abnormalities of the tear film are some of the hypotheses. The treatment is based onthe ocular discomfort degree and may be conservative or surgical, but this last one is still the bestoption. This paper aims to make a brief literature review of feline corneal sequestration, emphasizingits clinical features, possible etiologies and treatment

Revisão de literatura: Sequestro corneano felino / Literature Review: Feline Corneal Sequestrum

O seqüestro corneano é descrito na literatura desde 1964, sendo considerada uma afecção corneanaúnica de gatos, principalmente braquicefálicos. Relatos recentes descreveram este problema em cavaloe cão. Caracteriza-se, clinicamente, por uma placa marrom a preta, ovalada, de posição central ouparacentral na córnea e que provoca, dentre outros sinais, blefaroespasmo, fotofobia, epífora e hiperemiaconjuntival. Não há predisposição sexual e etária. A etiologia ainda não está definida, sendo aagressão crônica à córnea, infecção pelo herpesvirus felino tipo 1 (FHV-1) e anormalidades do filmelacrimal algumas das hipóteses. O tratamento baseia-se no grau de desconforto ocular, podendo serconservativo ou cirúrgico, mas este último ainda tem sido a melhor opção. Este trabalho tem por objetivofazer uma breve revisão de literatura sobre o seqüestro corneano felino, ressaltando seus sinaisclínicos, possíveis etiologias e tratamento(AU)

The corneal sequestration is described in the literature since 1964, and it is considered a corneal diseaseunique of cats, especially the brachycephalic breeds. Recent reports have described this problemin horse and dog. It is clinically characterized by a brown to black - oval shaped crust which positioncan be in the central or paracentral area of the cornea and causes, among other signs, blepharospasm,photophobia, epiphora and conjunctival hyperemia. There is no sexual or age predisposition. Theetiology is not defined yet, and the chronical aggression to cornea, feline herpesvirus type 1 (FHV-1)infection and abnormalities of the tear film are some of the hypotheses. The treatment is based onthe ocular discomfort degree and may be conservative or surgical, but this last one is still the bestoption. This paper aims to make a brief literature review of feline corneal sequestration, emphasizingits clinical features, possible etiologies and treatment(AU)

Veterinário mirim: ferramenta na educaçãoem saúde e promoção de cultura sobreguarda responsável e bem-estar animal / “Junior veterinary”: A tool on young students education in health promoting and responsible custody and animal welfare in the County of Pinhais/PR

Este trabalho teve como objetivo promover uma mudança cultural da população sobre guarda responsável e bem-estar animal, não omitindo o controle de zoonoses. Foram reali-zadas atividades sócio-educativas voltadas às crianças da rede fundamental de ensino como alternativa para atingir o objetivo proposto. O projeto de extensão “Controle de Zoonoses em Curitiba e Região Metropolitana” em parceria com o Centro de Controle de Zoonoses (CCZ) do município de Pinhais/PR, por meio do concurso “Veterinário Mirim”, realizou palestras, em 22 escolas públicas do município, no período de agosto a setembro de 2007. As palestras tratavam sobre zoonoses, bem-estar animal e guarda responsável e foram ministradas pelos acadêmicos do projeto aos alunos de 1a a 4a séries. Após isso, foi solicitado aos alunos que produzissem um desenho ou uma redação, ambos sobre os temas em questão, e os melhores trabalhos foram premiados com uma visita ao CCZ de Pinhais ou ao Hospital Veterinário da Universidade Federal do Paraná. Foi aplicado um questionário com perguntas sobre os temas abordados na palestra. Do total de 736 crianças, 601 (81,7%) relataram possuir animais em casa, sendo que 583 (96,2%) possuíam cães e gatos totalizando 1.406 animais. 389 (52,9%), afirmaram que seus animais têm acesso a rua e 267 (36,3%) assinalaram que seus animais já morderam alguém. O conceito de guarda responsável foi assinalado corretamente por 718 (97,6%) alunos. Conclui-se que a inclusão do “Veterinário Mirim” como política pública permitiu a incorporação da educação em guarda responsável nas escolas, transformando-as em promotoras de educação em saúde pública(AU)

This study aimed to promote a cultural change of the population regarding the subjects of responsible custody of animals and animal welfare, not omitting the control of zoonoses. Socio-educational activities were carried out aimed at children of the basic education as an alternative to achieve the proposed objective. The extension project “Control of Zoonoses in Curitiba and Surroundings” in partnership with the Zoonoses Control Center (CCZ) of Pinhais/ PR, through the competition “Junior Veterinary”, held lectures on 22 public schools on the county, in the period from August to September 2007. The lectures dealt on zoonoses, animal welfare and responsible custody and were administered by academics of the project to students from 1st to 4th grades. After that, students were asked to produce a drawing or writing, both on the issues concerned, and the best works were awarded with a visit to the CCZ of Pinhais or the Veterinary Hospital of the Federal University of Paraná. A questionnaire on the subject of the lectures was applied. Of the total of 736 children, 601 (81.7%) reported having animals at home, totaling 1.406 animals. 389 (52.9%), said that their animals have access to the street and 267 (36.3%) reported that their animals have bitten someone. The concept of responsible custody was correctly answered by 718 (97.6%) students. It can be concluded that the inclusion of “Junior Veterinary” as public policy has allowed the incorporation of education in responsible custody of animals on the schools, transforming them in forwarders of education in public health(AU)

Veterinário mirim: ferramenta na educaçãoem saúde e promoção de cultura sobreguarda responsável e bem-estar animal / “Junior veterinary”: A tool on young students education in health promoting and responsible custody and animal welfare in the County of Pinhais/PR

Este trabalho teve como objetivo promover uma mudança cultural da população sobre guarda responsável e bem-estar animal, não omitindo o controle de zoonoses. Foram reali-zadas atividades sócio-educativas voltadas às crianças da rede fundamental de ensino como alternativa para atingir o objetivo proposto. O projeto de extensão “Controle de Zoonoses em Curitiba e Região Metropolitana” em parceria com o Centro de Controle de Zoonoses (CCZ) do município de Pinhais/PR, por meio do concurso “Veterinário Mirim”, realizou palestras, em 22 escolas públicas do município, no período de agosto a setembro de 2007. As palestras tratavam sobre zoonoses, bem-estar animal e guarda responsável e foram ministradas pelos acadêmicos do projeto aos alunos de 1a a 4a séries. Após isso, foi solicitado aos alunos que produzissem um desenho ou uma redação, ambos sobre os temas em questão, e os melhores trabalhos foram premiados com uma visita ao CCZ de Pinhais ou ao Hospital Veterinário da Universidade Federal do Paraná. Foi aplicado um questionário com perguntas sobre os temas abordados na palestra. Do total de 736 crianças, 601 (81,7%) relataram possuir animais em casa, sendo que 583 (96,2%) possuíam cães e gatos totalizando 1.406 animais. 389 (52,9%), afirmaram que seus animais têm acesso a rua e 267 (36,3%) assinalaram que seus animais já morderam alguém. O conceito de guarda responsável foi assinalado corretamente por 718 (97,6%) alunos. Conclui-se que a inclusão do “Veterinário Mirim” como política pública permitiu a incorporação da educação em guarda responsável nas escolas, transformando-as em promotoras de educação em saúde pública

This study aimed to promote a cultural change of the population regarding the subjects of responsible custody of animals and animal welfare, not omitting the control of zoonoses. Socio-educational activities were carried out aimed at children of the basic education as an alternative to achieve the proposed objective. The extension project “Control of Zoonoses in Curitiba and Surroundings” in partnership with the Zoonoses Control Center (CCZ) of Pinhais/ PR, through the competition “Junior Veterinary”, held lectures on 22 public schools on the county, in the period from August to September 2007. The lectures dealt on zoonoses, animal welfare and responsible custody and were administered by academics of the project to students from 1st to 4th grades. After that, students were asked to produce a drawing or writing, both on the issues concerned, and the best works were awarded with a visit to the CCZ of Pinhais or the Veterinary Hospital of the Federal University of Paraná. A questionnaire on the subject of the lectures was applied. Of the total of 736 children, 601 (81.7%) reported having animals at home, totaling 1.406 animals. 389 (52.9%), said that their animals have access to the street and 267 (36.3%) reported that their animals have bitten someone. The concept of responsible custody was correctly answered by 718 (97.6%) students. It can be concluded that the inclusion of “Junior Veterinary” as public policy has allowed the incorporation of education in responsible custody of animals on the schools, transforming them in forwarders of education in public health

Estudo comparativo entre ropivacaína e lidocaína no bloqueio peribulbar em cães / Comparative ropivacaine and lidocaine study concerning canine peribulbar block

Baseado no crescimento das cirurgias intra-oculares e no avanço das técnicas de anestesia balanceadas, novos anestésicos locias devem ser explorados em medicina veterinária. A ropivacaína é um anestésico local tipo aminoamida, com longa duração, mínimos efeitos colaterais e baixa toxicidade. O objetivo deste estudo foi avaliar a eficácia desse agente nos bloqueios peribulbares em cães, comparativamente à lidocaína 2%. Foram relaizados 15 bloqueios peribulbares com ropivacaína 1% e comparados com lidocaína 2 % sem vasoconstritor. Foram avaliados a sensibilidade da córnea, a cinética do bulbo ocular, o diâmetro pupilar, o reflexo fotomotor, a pressão intra-ocular e a produção lacrimal. A ropivacaína apresentou um início d eação mais lento, mantendo um período anestésico de maior duração que o produzido pela lidocaína sem vasoconstritor. É bastante eficiente para manter bloqueio anestésico, sendo uma alternativa para a realização de bloqueios anestésicos na ofalmologia

Due to the intense growth intraocular surgeries in pets and the recent advances regarding balanced anesthesia and analgesia techniques, the use of new local anesthetics should be investigated in veterinary medicine. Ropivacaine is a new long lasting aminoamide local anesthetic, with minimum collateral effects and low toxicity. The objective of this study was to compare the anesthetica effectiveness of this new agent with lidocaine, when used in ophthalmic peribulbar blocks in dogs. 15 peribulbar blocks had bee performed with ropivacaine and lidocaine, in wich corneal analgesia, ocular akinesia, production of mydriasis, maintenance of the intraocular pressure and lacrimal production. Ropivacaine produced a longer period of anesthesia of satisfactory quality for the surgeon and for the anesthetist, being now considered a new alternative for the execution of ophthalmic blocks