ABSTRACT
BACKGROUND: This study aimed to investigate the choroidal vascularity index (CVI) in patients with computer vision syndrome (CVS) combined with accommodative lead. METHODS: This retrospective case-control study enrolled patients diagnosed with CVS and accommodative lead at University-Town Hospital of Chongqing Medical University between July 2022 and May 2023. The control group included individuals without any ocular diseases. Ophthalmic assessments included basic visual acuity, refraction, ocular biometric parameters, and CVI. RESULTS: A total of 85 participants were included in the study, with 45 in the CVS group and 40 in the control group. The central corneal thickness of CVS group was found to be significantly thinner compared to the control group in both the right eye (532.40±30.93 vs. 545.78±19.99 µm, P = 0.019) and left eye (533.96±29.57 vs. 547.56±20.39, P = 0.014). In comparison to the control group, the CVS group exhibited lower CVI in the superior (0.40±0.08 vs. 0.43±0.09, P = 0.001), temporal (0.40±0.08 vs. 0.44±0.10, P < 0.001), inferior (0.41±0.08 vs. 0.46±0.08, P < 0.001), and nasal (0.41±0.08 vs. 0.44±0.08, P = 0.001) quadrants. Similar differences were observed in all four quadrants within the 1-3 mm radius, and in the temporal (P = 0.004) and inferior (P = 0.002) quadrants within the 1-6 mm and 3-6 mm radii (all P < 0.05). CONCLUSION: Compared to individuals without ocular issues, patients with CVS and accommodative lead were found to have thinner corneal central thickness and lower CVI.