A topological Hund nodal line antiferromagnet.

The interplay of topology, magnetism, and correlations gives rise to intriguing phases of matter. In this study, through state-of-the-art angle-resolved photoemission spectroscopy, density functional theory, and dynamical mean-field theory calculations, we visualize a fourfold degenerate Dirac nodal line at the boundary of the bulk Brillouin zone in the antiferromagnet YMn2Ge2. We further demonstrate that this gapless, antiferromagnetic Dirac nodal line is enforced by the combination of magnetism, space-time inversion symmetry, and nonsymmorphic lattice symmetry. The corresponding drumhead surface states traverse the whole surface Brillouin zone. YMn2Ge2 thus serves as a platform to exhibit the interplay of multiple degenerate nodal physics and antiferromagnetism. Interestingly, the magnetic nodal line displays a d-orbital dependent renormalization along its trajectory in momentum space, thereby manifesting Hund's coupling. Our findings offer insights into the effect of electronic correlations on magnetic Dirac nodal lines, leading to an antiferromagnetic Hund nodal line.

Tunable optical matrix convolution of 20-Gbit/s QPSK 2-D data with a kernel using optical wave mixing.

Compared to its electronic counterpart, optically performed matrix convolution can accommodate phase-encoded data at high rates while avoiding optical-to-electronic-to-optical (OEO) conversions. We experimentally demonstrate a reconfigurable matrix convolution of quadrature phase-shift keying (QPSK)-encoded input data. The two-dimensional (2-D) input data is serialized, and its time-shifted replicas are generated. This 2-D data is convolved with a 1-D kernel with coefficients, which are applied by adjusting the relative phase and amplitude of the kernel pumps. Time-shifted data replicas (TSDRs) and kernel pumps are coherently mixed using nonlinear wave mixing in a periodically poled lithium niobate (PPLN) waveguide. To show the tunability and reconfigurability of this approach, we vary the kernel coefficients, kernel sizes (e.g., 2 × 1 or 3 × 1), and input data rates (e.g., 6-20 Gbit/s). The convolution results are verified to be error-free under an applied: (a) 2 × 1 kernel, resulting in a 16-quadrature amplitude modulation (QAM) output with an error vector magnitude (EVM) of ∼5.1-8.5%; and (b) 3 × 1 kernel, resulting in a 64-QAM output with an EVM of ∼4.9-5.5%.

Demonstration of an 8-Gbit/s quadrature-phase-shift-keying coherent underwater wireless optical communication link using coherent heterodyne detection under scattering conditions.

In this paper, we experimentally demonstrate an 8-Gbit/s quadrature-phase-shift-keying (QPSK) coherent underwater wireless optical communication (UWOC) link under scattering conditions at 532 nm. At the transmitter, we generate the 532-nm QPSK signal using second-harmonic generation (SHG), where the 1064-nm signal modulated with four phase levels of an 8-phase-shift-keying (8-PSK) format is phase doubled to produce the 532-nm QPSK signal. To enhance the receiver sensitivity, we utilize a local oscillator (LO) at the receiver from an independent laser source. The received QPSK data beam is mixed with the independent LO for coherent heterodyne detection. Results show that the bit error rates (BERs) of the received QPSK signal can reach below the 7% forward error correction (FEC) limit under turbid water with attenuation lengths (γL) up to 7.4 and 6.1 for 2- and 8-Gbit/s QPSK, respectively. The corresponding receiver sensitivities are -34.0 and -28.4 dBm for 2- and 8-Gbit/s QPSK, respectively.

Turbulence mitigation of four mode-division-multiplexed QPSK channels in a pilot-assisted self-coherent free-space optical link using a photodetector array and DSP-based channel demultiplexing.

In this Letter, we demonstrate turbulence mitigation of four mode-division-multiplexing (MDM) quadrature-phase-shift-keying (QPSK) channels in a pilot-assisted self-coherent free-space optical (FSO) link using a photodetector (PD) array and digital signal processing (DSP)-based channel demultiplexing. A Gaussian pilot beam is co-transmitted with four 1-Gbaud QPSK channels carried by four orbital angular momentum (OAM) modes. The pilot beam experiences similar turbulence-induced wavefront distortion to the data beams. At the receiver, the turbulence distortion is mitigated by its conjugate during the pilot-data mixing in a PD array. Subsequently, we demultiplex the four channels by applying in DSP a fixed matrix on the signals. Results show that our approach has <3-dB turbulence-induced power penalty at a 7% forward error correction (FEC) limit under a turbulence strength of 2w0/r0 = ∼4.4. The same turbulence can cause >18-dB penalties for a local oscillator (LO)-based coherent MDM system.

Adaptive-optics-based turbulence mitigation in a 400 Gbit/s free-space optical link by multiplexing Laguerre-Gaussian modes varying both radial and azimuthal spatial indices: publisher's note.

This publisher's note contains a correction to Opt. Lett.48, 6452 (2023)10.1364/OL.506270.

Adaptive-optics-based turbulence mitigation in a 400†Git/s free-space optical link by multiplexing Laguerre-Gaussian modes varying both radial and azimuthal spatial indices.

In general, atmospheric turbulence can degrade the performance of free-space optical (FSO) communication systems by coupling light from one spatial mode to other modes. In this Letter, we experimentally demonstrate a 400 Gbit/s quadrature-phase-shift-keyed (QPSK) FSO mode-division-multiplexing (MDM) coherent communication link through emulated turbulence using four Laguerre Gaussian (LG) modes with different radial and azimuthal indices (L G 10, L G 11, L G -10, and L G -11). To mitigate turbulence-induced channel cross talk and power loss, we implement an adaptive optics (AO) system at the receiver end. A Gaussian beam at a slightly different wavelength is co-propagated with the data beams as the probe beam. We use a wavefront sensor (WFS) to measure the wavefront distortion of this probe beam, and this information is used to tune a spatial light modulator (SLM) to adaptively correct the four distorted data-beam wavefronts. Using this adaptive-optics approach, the power loss and cross talk are reduced by ∼10 and ∼18 dB, respectively.

Space-time wave packets with reduced divergence and tunable group velocity generated in free space after multi-mode fiber propagation.

Previously, space-time wave packets (STWPs) have been generated in free space with reduced diffraction and a tunable group velocity by combining multiple frequency comb lines each carrying a single Bessel mode with a unique wave number. It might be potentially desirable to propagate the STWP through fiber for reconfigurable positioning. However, fiber mode coupling might degrade the output STWP and distort its propagation characteristics. In this Letter, we experimentally demonstrate STWP generation and propagation over 1-m graded-index multi-mode fiber. Fiber mode coupling is mitigated by pre-distortion according to the inverse matrix of the fiber mode coupling matrix. Measurement of the STWP at the fiber output shows that its group velocity can vary from 1.0042c to 0.9967c by tuning the wave number of the Bessel mode on each frequency. The measured time-averaged intensity profiles show that the beam radius remains similar after 150-mm free-space propagation after exiting the fiber.

Demonstration of optically-assisted reconfigurable average of two 20-Gbaud 4-phase-encoded data channels using nonlinear wave mixing.

Networks can play a key role in high-speed and reconfigurable arithmetic computing. However, two performance bottlenecks may arise when: (i) relying solely on electronics to handle computation for multiple data channels at high data rates, and (ii) the data streams input to a processing node (PN) are transmitted as phase-encoded signals over an optical network. We experimentally demonstrate the operation of optically-assisted reconfigurable average of two 4-phase-encoded data channels at 10- and 20-Gbaud rates. Our input signals are two streams of 2-bit numbers representing a binary floating-point format, and the operation results in 7-phase-encoded output signals represented by 3-bit numbers. The average operation is achieved in three stages: (1) phase encoding and division-using an optical modulator to encode the data streams; (2) summation-using a highly nonlinear fiber (HNLF); and (3) multicast-using a periodically poled lithium niobate (PPLN) waveguide to multicast back the result into the original signal wavelengths. The experimental results validate the concept, and the measured penalties indicate that: (i) the error vector magnitudes (EVMs) of optical signals increase at each stage and reach ∼18-21% for the final multicast results, and (ii) compared to the inputs, the optical signal-to-noise ratio (OSNR) penalty of output is ∼6.7 dB for the 10-Gbaud rate and ∼6.9 dB for the 20-Gbaud rate at a bit error rate (BER) of 3.8e-3.

Atmospheric turbulence strength distribution along a propagation path probed by longitudinally structured optical beams.

Atmospheric turbulence can cause critical problems in many applications. To effectively avoid or mitigate turbulence, knowledge of turbulence strength at various distances could be of immense value. Due to light-matter interaction, optical beams can probe longitudinal turbulence changes. Unfortunately, previous approaches tended to be limited to relatively short distances or large transceivers. Here, we explore turbulence probing utilizing multiple sequentially transmitted longitudinally structured beams. Each beam is composed of Bessel-Gaussian ([Formula: see text]) modes with different [Formula: see text] values such that a distance-varying beam width is produced, which results in a distance- and turbulence-dependent modal coupling to [Formula: see text] orders. Our simulation shows that this approach has relatively uniform and low errors (<0.3 dB) over a 10-km path with up to 30-dB turbulence-structure-constant variation. We experimentally demonstrate this approach for two emulated turbulence regions (~15-dB variation) with <0.8-dB errors. Compared to previous techniques, our approach can potentially probe longer distances or require smaller transceivers.

Experimental demonstration of an optics-based 4-PSK half-adder using nonlinear wave mixing.

We experimentally demonstrate an optics-based half-adder of two 4-phase-shift-keying (4-PSK) data channels using nonlinear wave mixing. The optics-based half-adder has two 4-ary phase-encoded inputs (i.e., SA and SB) and two phase-encoded outputs (i.e., Sum and Carry). The input quaternary base numbers {0,1,2,3} are represented by 4-PSK signals A and B with four phase levels. Along with the original signals A and B, the phase-conjugate signal copies A* and B*and phase-doubled signal copies A2 and B2 are also generated to form two signal groups SA(A, A*, A2) and SB(B, B*, B2). All of the above signals in the same signal group are (a) prepared in the electrical domain with a frequency spacing of Δf and (b) generated optically in the same IQ modulator. When combined with a pump laser, group SA mixes with group SB in a periodically poled lithium niobate nonlinear (PPLN) device. At the output of the PPLN device, both the Sum (A2B2) and the Carry (AB + A*B*) are simultaneously generated with four phase levels and two phase levels, respectively. In our experiment, the symbol rates can be varied between 5 Gbaud and 10 Gbaud. The experimental results show that (i) the measured conversion efficiency of two 5-Gbaud outputs is approximately -24 dB for Sum and approximately -20 dB for Carry, and (ii) the measured optical signal-to-noise ratio (OSNR) penalty of the 10-Gbaud Sum and Carry channels is <10 dB and <5 dB, compared with that of the 5-Gbaud channels at the BER of 3.8 × 10-3.

Automatic turbulence mitigation for coherent free-space optical links using crystal-based phase conjugation and fiber-coupled data modulation.

There are various performance advantages when using temporal phase-based data encoding and coherent detection with a local oscillator (LO) in free-space optical (FSO) links. However, atmospheric turbulence can cause power coupling from the Gaussian mode of the data beam to higher-order modes, resulting in significantly degraded mixing efficiency between the data beam and a Gaussian LO. Photorefractive crystal-based self-pumped phase conjugation has been previously demonstrated to "automatically" mitigate turbulence with limited-rate free-space-coupled data modulation (e.g., <1 Mbit/s). Here, we demonstrate automatic turbulence mitigation in a 2-Gbit/s quadrature-phase-shift-keying (QPSK) coherent FSO link using degenerate four-wave-mixing (DFWM)-based phase conjugation and fiber-coupled data modulation. Specifically, we counter-propagate a Gaussian probe from the receiver (Rx) to the transmitter (Tx) through turbulence. At the Tx, we generate a Gaussian beam carrying QPSK data by a fiber-coupled phase modulator. Subsequently, we create a phase conjugate data beam through a photorefractive crystal-based DFWM involving the Gaussian data beam, the turbulence-distorted probe, and a spatially filtered Gaussian copy of the probe beam. Finally, the phase conjugate beam is transmitted back to the Rx for turbulence mitigation. Compared to a coherent FSO link without mitigation, our approach shows up to ∼14-dB higher LO-data mixing efficiency and achieves error vector magnitude (EVM) performance of <16% under various turbulence realizations.

Generation of OAM-carrying space-time wave packets with time-dependent beam radii using a coherent combination of multiple LG modes on multiple frequencies.

Space-time (ST) wave packets, in which spatial and temporal characteristics are coupled, have gained attention due to their unique propagation characteristics, such as propagation invariance and tunable group velocity in addition to their potential ability to carry orbital angular momentum (OAM). Through experiment and simulation, we explore the generation of OAM-carrying ST wave packets, with the unique property of a time-dependent beam radius at various ranges of propagation distances. To achieve this, we synthesize multiple frequency comb lines, each assigned to a coherent combination of multiple Laguerre-Gaussian (LGℓ,p) modes with the same azimuthal index but different radial indices. The time-dependent interference among the spatial modes at the different frequencies leads to the generation of the desired OAM-carrying ST wave packet with dynamically varying radii. The simulation results indicate that the dynamic range of beam radius oscillations increases with the number of modes and frequency lines. The simulated ST wave packet for OAM of orders +1 or +3 has an OAM purity of >95%. In addition, we experimentally generate and measure the OAM-carrying ST wave packets with time-dependent beam radii. In the experiment, several lines of a Kerr frequency comb are spatially modulated with the superposition of multiple LG modes and combined to generate such an ST wave packet. In the experiment, ST wave packets for OAM of orders +1 or +3 have an OAM purity of >64%. In simulation and experiment, OAM purity decreases and beam radius becomes larger over the propagation.

High-capacity free-space optical communications using wavelength- and mode-division-multiplexing in the mid-infrared region.

Due to its absorption properties in atmosphere, the mid-infrared (mid-IR) region has gained interest for its potential to provide high data capacity in free-space optical (FSO) communications. Here, we experimentally demonstrate wavelength-division-multiplexing (WDM) and mode-division-multiplexing (MDM) in a ~0.5 m mid-IR FSO link. We multiplex three ~3.4 µm wavelengths (3.396 µm, 3.397 µm, and 3.398 µm) on a single polarization, with each wavelength carrying two orbital-angular-momentum (OAM) beams. As each beam carries 50-Gbit/s quadrature-phase-shift-keying data, a total capacity of 300 Gbit/s is achieved. The WDM channels are generated and detected in the near-IR (C-band). They are converted to mid-IR and converted back to C-band through the difference frequency generation nonlinear processes. We estimate that the system penalties at a bit error rate near the forward error correction threshold include the following: (i) the wavelength conversions induce ~2 dB optical signal-to-noise ratio (OSNR) penalty, (ii) WDM induces ~1 dB OSNR penalty, and (iii) MDM induces ~0.5 dB OSNR penalty. These results show the potential of using multiplexing to achieve a ~30X increase in data capacity for a mid-IR FSO link.

Multi-dimensional data transmission using inverse-designed silicon photonics and microcombs.

The use of optical interconnects has burgeoned as a promising technology that can address the limits of data transfer for future high-performance silicon chips. Recent pushes to enhance optical communication have focused on developing wavelength-division multiplexing technology, and new dimensions of data transfer will be paramount to fulfill the ever-growing need for speed. Here we demonstrate an integrated multi-dimensional communication scheme that combines wavelength- and mode- multiplexing on a silicon photonic circuit. Using foundry-compatible photonic inverse design and spectrally flattened microcombs, we demonstrate a 1.12-Tb/s natively error-free data transmission throughout a silicon nanophotonic waveguide. Furthermore, we implement inverse-designed surface-normal couplers to enable multimode optical transmission between separate silicon chips throughout a multimode-matched fibre. All the inverse-designed devices comply with the process design rules for standard silicon photonic foundries. Our approach is inherently scalable to a multiplicative enhancement over the state of the art silicon photonic transmitters.

Synthesis of near-diffraction-free orbital-angular-momentum space-time wave packets having a controllable group velocity using a frequency comb.

Novel forms of light beams carrying orbital angular momentum (OAM) have recently gained interest, especially due to some of their intriguing propagation features. Here, we experimentally demonstrate the generation of near-diffraction-free two-dimensional (2D) space-time (ST) OAM wave packets (ℓ = +1, +2, or +3) with variable group velocities in free space by coherently combining multiple frequency comb lines, each carrying a unique Bessel mode. Introducing a controllable specific correlation between temporal frequencies and spatial frequencies of these Bessel modes, we experimentally generate and detect near-diffraction-free OAM wave packets with high mode purities (>86%). Moreover, the group velocity can be controlled from 0.9933c to 1.0069c (c is the speed of light in vacuum). These ST OAM wave packets might find applications in imaging, nonlinear optics, and optical communications. In addition, our approach might also provide some insights for generating other interesting ST beams.

Utilizing multiplexing of structured THz beams carrying orbital-angular-momentum for high-capacity communications.

Structured electromagnetic (EM) waves have been explored in various frequency regimes to enhance the capacity of communication systems by multiplexing multiple co-propagating beams with mutually orthogonal spatial modal structures (i.e., mode-division multiplexing). Such structured EM waves include beams carrying orbital angular momentum (OAM). An area of increased recent interest is the use of terahertz (THz) beams for free-space communications, which tends to have: (a) larger bandwidth and lower beam divergence than millimeter-waves, and (b) lower interaction with matter conditions than optical waves. Here, we explore the multiplexing of THz OAM beams for high-capacity communications. Specifically, we experimentally demonstrate communication systems with two multiplexed THz OAM beams at a carrier frequency of 0.3 THz. We achieve a 60-Gbit/s quadrature-phase-shift-keying (QPSK) and a 24-Gbit/s 16 quadrature amplitude modulation (16-QAM) data transmission with bit-error rates below 3.8 × 10-3. In addition, to show the compatibility of different multiplexing approaches (e.g., polarization-, frequency-, and mode-division multiplexing), we demonstrate an 80-Gbit/s QPSK THz communication link by multiplexing 8 data channels at 2 polarizations, 2 frequencies, and 2 OAM modes.

Receiver aperture and multipath effects on power loss and modal crosstalk in a THz wireless link using orbital-angular-momentum multiplexing.

The channel capacity of terahertz (THz) wireless communications can be increased by multiplexing multiple orthogonal data-carrying orbital-angular-momentum (OAM) beams. In THz links using OAM multiplexing (e.g., Laguerre-Gaussian [Formula: see text] beams with p = 0), the system performance might degrade due to limited receiver aperture size and multipath effects. A limited-size aperture can truncate the received beam profile along the radial direction. In addition, due to beam divergence, part of the beam might interact with reflectors in the environment, causing the signal to reflect and interfere at the receiver with the directly propagating part of the beam; this is known as the multipath effect. In this paper, we simulate and analyze the impact of both effects on the equality of the THz OAM link by considering a full two-dimensional (2-D) LG modal set. The simulation results show (i) a limited-size receiver aperture can induce power loss and modal power coupling mainly to LG modes with the same ℓ but p > 0 for directly propagated OAM beams; (ii) the multipath effect can induce modal power coupling across multiple 2-D LG modes, which leads to inter-channel coupling among the different channels in an OAM multiplexed link; (iii) the interference between the reflected and direct beams can induce intra-channel coupling between the received signals from the reflected and direct beams; and (iv) beams with a higher OAM order (e.g., from ± 1 to ± 5) or a lower carrier frequency (e.g., from 0.1 to 1 THz) experience larger intra- and inter-channel coupling. The intra- and inter-channel coupling in an OAM-multiplexed THz link can degrade the signal-to-noise ratio (SNR) and induce SNR penalty when compared to a single-channel system.

Demonstration of turbulence mitigation in a 200-Gbit/s orbital-angular-momentum multiplexed free-space optical link using simple power measurements for determining the modal crosstalk matrix.

We experimentally demonstrate turbulence mitigation in a 200-Gbit/s quadrature phase-shift keying (QPSK) orbital-angular-momentum (OAM) mode-multiplexed system using simple power measurements for determining the modal coupling matrix. To probe and mitigate turbulence, we perform the following: (i) sequentially transmit multiple probe beams at 1550-nm wavelength each with a different combination of Laguerre-Gaussian (LG) modes; (ii) detect the power coupling of each probe beam to LG0,0 for determining the complex modal coupling matrix; (iii) calculate the conjugate phase of turbulence-induced spatial phase distortion; (iv) apply this conjugate phase to a spatial light modulator (SLM) at the receiver to mitigate the turbulence distortion for the 1552-nm mode-multiplexed data-carrying beams. The probe wavelength is close enough to the data wavelength such that it experiences similar turbulence, but is far enough away such that the probe beams do not affect the data beams and can all operate simultaneously. Our experimental results show that with our turbulence mitigation approach the following occur: (a) the inter-channel crosstalk is reduced by ∼25 and ∼21 dB for OAM +1 and -2 channels, respectively; (b) the optical signal-to-noise ratio (OSNR) penalty is <1 dB for both OAM channels for a bit error rate (BER) at the 7% forward error correction (FEC) limit, compared with the no turbulence case.

The Regulatory Role of SNORD35A in Pancreatic Cancer Involves the HGF/C-Met Pathway.

Background: Pancreatic adenocarcinoma (PAAD) is a type of malignant tumors in the digestive tract. It is extremely aggressive. However, the molecular mechanism of the occurrence and development of pancreatic cancer has not yet been elucidated. New evidence shows that the dysregulation of small nucleolar RNAs (SnoRNAs) plays an important role in tumorigenesis and has a certain connection with tumor stem cells. In this study, we screened differentially expressed SnoRNAs in pancreatic cancer, further explored whether the HGF/C-Met pathway is involved in the regulation of SNORD35A in pancreatic cancer stem cells. Materials and Methods: AffymetrixmiRNA 4.0 and QRT-PCR was used for differential screening of SnoRNA. CCK8, wound healing assay and TransWell chamber were used to detect cell proliferation, migration and invasion. QRT-PCR was used to detect the changes of epithelial - mesenchymal Transition (EMT) related genes of tumors. We detected the expression levels of HGF/C-Met pathway and its related proteins by Western blotting. Result: We found that SNORD35A is significantly overexpressed in pancreatic cancer. After disturbing the expression of SNORD35A, the epithelial markers increased and the mesenchymal markers decreased during the EMT process. At the same time, down-regulation of SNORD35A inhibited the proliferation, migration and invasion of pancreatic cancer stem cells in cellular level. In nude mouse transplanted tumor models, low expression of SNORD35A reduced tumor growth volume and attenuated its pathological features. Finally, we found that silencing SNORD35A reduced the expression levels of C-Met and its phosphorylated proteins. Conclusion: These results suggest that the regulation of SNORD35A on proliferation, migration, invasion and EMT of pancreatic cancer stem cells involves HGF/C-Met signaling pathway. SNORD35A has carcinogenic effects in pancreatic cancer and may become a prognostic biomarker and therapeutic target for pancreatic cancer patients.

Dendritic Cell Vaccine Loaded with MG-7 Antigen Induces Cytotoxic T Lymphocyte Responses against Gastric Cancer.

Dendritic cells (DCs) are antigen-presenting cells that can activate T cells and initiate a primary immune response. Personalized DC vaccines have demonstrated a modest antitumor potential in some clinical pilot studies. However, those vaccines are difficult to manufacture and have a limited antitumor response. In this study, a lentiviral vector-programmed DC vaccine with high antitumor responses is developed. By transfecting with a lentiviral vector, the DC vaccine is loaded with MG-7 antigen (MG-7Ag). Three representative gastric cancer cell lines, such as KATO-3, MKN45, and SNU16, are used to estimate the in vitro cytotoxic effect of the MG-7Ag DC vaccine. Furthermore, we examine the in vivo antitumor efficacy of specific cytotoxic T lymphocytes (CTLs) induced by the MG-7Ag DC vaccine in patient-derived xenograft (PDX) mice models. The current data demonstrate that the MG-7Ag DC vaccine induced a potent CTL activity. Those CTLs have a significant cytotoxic effect on both KATO-3 and MKN45 with high level of MG-7 expression. In addition, MG-7Ag DC vaccine-mediated CTLs significantly inhibit the growth of tumor xenografts in nude mice. The MG-7Ag DC vaccine activate the cytotoxic effect of lymphocytes and can be employed as a vaccine in gastric cancer immunotherapy.