Evaluation of comfort gloves made of semipermeable and textile materials in patients with hand dermatoses: Results of a controlled multicenter intervention study (ProTection II).

BACKGROUND: Comfort gloves are used in the management of hand dermatoses. OBJECTIVES: To compare the acceptance and tolerability of comfort gloves made of different materials in patients with hand dermatoses and their effects on skin lesions. METHODS: In a prospective multicenter study, 284 patients with hand dermatoses were invited to wear either a cotton glove (COT) or a semipermeable Sympatex glove underneath a cotton glove (SYM/COT) for two subsequent phases of 19 consecutive nights each. A total of 88 controls were asked not to wear any comfort gloves overnight. The severity of skin lesions over time was examined. Questionnaires were used to assess health-related quality of life (HRQoL) and acceptance and tolerability of the gloves. RESULTS: The hand dermatoses improved in all groups. No substantial intergroup differences regarding severity and HRQoL were observed. SYM/COT received better ratings regarding climate conditions and tactility while COT showed superiority in fit, wearing comfort, and practicality. CONCLUSIONS: We confirmed that SYM/COT and COT are well tolerated and accepted suggesting that SYM/COT is a good alternative for COT as comfort gloves in patients with hand dermatoses. Individual requirements, needs, and preferences may direct the material choice.

Impact of different concentration iodinated contrast media on pain and comfort in abdominal computed tomography.

OBJECTIVES: To investigate whether high concentration iodinated contrast media (CM), compared with low concentration CM, could reduce pain and discomfort levels in patients who had level II and III venous conditions. METHODS: This prospective, single-center study enrolled patients who had level II and III venous conditions and underwent abdominal contrast-enhanced CT scan between July 2021 and February 2022. The venous condition to establish peripheral venous access for CM injection was graded using the Intravenous Access Scoring system, of which level II and III indicated poor venous condition and difficult venous access. Patients received iomeprol 400 in high concentration group and ioversol 320 in low group at an identical iodine delivery rate of 1.12 gI/s. The primary outcomes were pain and comfort levels. The secondary outcomes included adverse events and image quality. Patients rated pain intensity via Numerical Rating Scale and comfort level via Visual Analogue Scale with higher scores indicating higher levels of pain and discomfort. Quantitative and qualitative image assessment were compared between two groups. Continuous variables were compared using Student's t test or Mann-Whitney U test. Categorical variables were compared using χ2 test, χ2 test for trend or Fisher's exact test. RESULTS: A total of 206 patients (mean age, 60.13 ± 12.14 years; 81 males) were included with 99 in the high concentration group and 107 in the low concentration group. The high group had significantly lower pain scores (median 1 [IQR: 0-2] vs 2 (IQR 2-4), p < 0.001) and comfort scores (1 [IQR: 0-3] vs 3 [IQR: 2-5], p < 0.001) than the low group. Incidence of CM extravasation did not significantly differ (1.0 % vs 4.5 %, p = 0.214). No hypersensitivity reaction was observed. Qualitative assessment showed higher clarity scores of intrahepatic hepatic artery and portal vein in the high group. Quantitative assessment results were comparable between two groups. CONCLUSION: High concentration iodinated CM could lower pain intensity and improve comfort levels without comprising image quality of CT scan. High concentration CM is a preferable choice in patients with poor venous conditions during contrast-enhanced CT scan.

Factors Associated With the Initiation of Comfort-Focused Nutrition Care Orders for Long-Term Care Residents at End of Life.

BACKGROUND: Comfort-focused nutrition orders are recommended to manage eating changes among long-term care (LTC) residents nearing the end of life, though little is known about their current use. This investigation aims to describe current practices and identify resident-level and time-dependent factors associated with comfort-focused nutrition orders in this context. METHODS: Data were retrospectively extracted from resident charts of decedents (≥65 years at death, admitted ≥6 months) in 18 LTC homes from two sampling frames across southern Ontario, Canada. Observations occurred at 6 months (baseline), 3 months, 1 month and 2 weeks prior to death. Extracted data included functional measures (e.g. cognitive performance, health instability) at baseline, formalised restorative and comfort-focused nutrition care interventions at each timepoint and eating changes reported in the progress notes in 2 weeks following each timepoint. Logistic regression and time-varying logistic regression models determined resident-level (e.g. functional characteristics) and time-dependent factors (e.g. eating changes) associated with receiving a comfort-focused nutrition order. RESULTS: Less than one-third (30.5%; n = 50) of 164 participants (61.0% female; mean age = 88.3 ± 7.5 years) received a comfort-focused nutrition order, whereas most (99%) received at least one restorative nutrition intervention to support oral food intake. Discontinuation of nutrition interventions was rare (8.5%). Comfort orders were more likely with health instability (OR [95% CI] = 4.35 [1.49, 13.76]), within 2 weeks of death (OR = 5.50 [1.70, 17.11]), when an end-of-life conversation had occurred since the previous timepoint (OR = 5.66 [2.83, 11.33]), with discontinued nutrition interventions (OR = 6.31 [1.75, 22.72]), with co-occurrence of other care plan modifications (OR = 1.48 [1.10, 1.98]) and with a greater number of eating changes (OR = 1.19 [1.02, 1.38]), especially dysphagia (OR = 2.59 [1.09, 6.17]), at the preceding timepoint. CONCLUSIONS: Comfort-focused nutrition orders were initiated for less than one-third of decedents and most often in the end stages of life, possibly representing missed opportunities to support the quality of life for this vulnerable population. An increase in eating changes, including new dysphagia, may signal a need for proactive end-of-life conversations involving comfort nutrition care options. IMPLICATIONS FOR PRACTICE: Early and open conversations with residents and family about potential eating changes and comfort-focused nutrition care options should be encouraged and planned for among geriatric nursing teams working in LTC. These conversations may be beneficial even as early as resident admission to the home.

Modeling passenger comfort in turboprop aircraft using objective measures.

BACKGROUND: A quantitative comfort model will aid in evaluating comfort levels of various target groups before the actual flight of an airplane. However, constructing the model is always a challenge due to the complexity of the phenomenon. OBJECTIVES: In this paper, we present quantitative comfort models to predict the (dis)comfort of passengers flying with turboprops based on objective measures. METHODS: Ninety-seven participants took part in two experiments conducted during real flights, during which forty of them had environmental and personal factors recorded using (self-developed) measurement tools. The collected data were analyzed to model the relations between objective measures and subjective feelings. RESULTS: Two preliminary models based on gradient boosting regression were developed. The models were able to predict the changes in comfort and discomfort of individual passengers with an accuracy of 0.12±0.01 and 0.21±0.01 regarding normalized comfort and discomfort scores, respectively. Additionally, contributions of different factors were highlighted. CONCLUSION: The outcomes of the models show that we took a step forward in modeling the human comfort experience using objective measurements. Anthropometry (including age), seat positions, time duration, and row (noise) emerged as leading factors influencing the feeling of (dis)comfort in turboprop planes.

Neural correlates of distress and comfort in individuals with avoidant, anxious and secure attachment style: an fMRI study.

Despite a growing literature, experiments directly related to attachment are still needed. We explored brain processes involved in two aspects of attachment, distress and comfort. Seventy-eight healthy adult males with different attachment styles (secure, avoidant, and anxious) viewed distress, comfort, complicity-joy and neutral images (picture database BAPS-Adult) in an fMRI block design. ROIs from the modules described in the functional Neuro-Anatomical Model of Attachment (Long et al. 2020) were studied. Secure participants used more co- and self-regulation strategies and exhibited a higher activation of the reward network in distress and comfort viewing, than insecure participants. Avoidant participants showed the lower brain activations. Their approach and reward modules were the least activated in distress and comfort. Anxious participants presented both higher activations of the approach and aversion modules during complicity-joy. In addition, comfort and complicity-joy were processed differently according to attachment styles and should be differentiated among positive stimuli to disentangle attachment processes.

Anticipation (second-order motor planning) is stored in memory - processing of grasp postures in a priming paradigm.

The end-state comfort effect (ESC) describes the tendency to grasp an object with an initial uncomfortable grasp posture in order to achieve a comfortable end posture. The ESC is an example for anticipative processes in manual action. ESC planning is investigated in many studies where this effect is measured in the context of motor observation and motion capture. However, there is little evidence if the anticipative link between different action states, especially between initial grasp postures and comfortable end postures, is represented in memory. The aim of the present study was to investigate whether the perception of a grasp posture holding a bar leads to the activation of action-related representations of grasping actions. For this purpose, a priming paradigm was used in which prime images were shown depicting either a comfortable (overhand grip) or uncomfortable (underhand grip) grasp posture holding a two-colored bar. The subsequently shown target images represented either a comfortable (thumb-up) or uncomfortable (thumb-down) final grasp posture of this grasping action. Due to the different grasp postures in the prime and target, prime-target pairs represented different types of action sequences. Furthermore, physically possible, and physically impossible actions were presented. Participants were asked to react to the top color of the bar shown in the target-picture, whereby the shown grasp posture was irrelevant for this decision. Results showed that reaction times did not differ after presentation of an overhand grip to target pictures showing comfortable or uncomfortable final grasp postures. In contrast, after presentation of an underhand grip in the prime, reactions to target pictures with final comfortable grasp postures were faster compared to target pictures with uncomfortable grasp postures. The effect was only found for the physically possible action. The findings suggest that the perception of the underhand grip leads to cognitive pre-activation of a final action state. The present study suggests that the association between an initial uncomfortable underhand grip and its action effect, in form of a final action state that is consistent with the ESC, is represented in memory. Such motor representation might be important for the anticipation and control of goal-directed grasping.

Energy consumption and thermal comfort of rock-cut and modern buildings.

Energy consumption in the building sector justifies the necessity of knowing the thermal comfort perception of vernacular and modern architectural types, based on which a correct recognition was reached for the design of buildings suitable for the climatic conditions of each region. It should be determined that the different types of modern and traditional architecture are in the comfort level in harsh hot climate conditions and how much energy they consume to reach the comfort level. Despite consideration of energy consumption and thermal comfort in different buildings in Iran, there is no clear framework for evaluating these two parameters in different buildings and comparing them. This research aims to compare the indoor thermal comfort levels of vernacular architectural buildings and modern buildings in Iran's semi-hot and dry climate at the peak of summer heat and determine their energy consumption to reach the comfort level. This study has been accomplished by collecting field data, examining the indoor predicted mean vote (PMV) index of the buildings, and comparing them. It was found that rock-cut architecture buildings are in better thermal comfort conditions without energy consumption due to the use of groundmass temperature and low heat exchanges between the indoors and outdoors because of the thermal phase of the materials and the thickness of its layers. The indoor PMV average of rock-cut buildings in summer is -0.61; in modern buildings, it is 0.77, while these two building complexes are in the same climate and close. Also, the energy consumption to reach the comfort level in rock-cut buildings is zero, while modern buildings consume an average of 7.7 kW of electricity daily. The research results will lead to recognizing and modeling the climate design of vernacular architecture, which can be used in today's architecture to reduce energy consumption.

Influence of Human Activity on Radon Concentration, Indoor Air Quality, and Thermal Comfort in Small Office Spaces.

This article focuses on the influence of occupants on the concentration of contaminants (radon Rn-222 and CO2) as well as the thermal comfort parameters. A series of sensors were placed to measure the concentration of the contaminants, temperature, and relative humidity in the test room at the Institute of Nuclear Physics PAN in Krakow (IFJ PAN), Poland. The test room is an office that is typical of the offices used in the facility. The occupants that used the space kept a detailed diary of their entry, exit, and number of people entering. The results showed that the accumulation of contaminants in such spaces may be severe and risks the health and safety of occupants. The accumulation of CO2 was extremely noticeable and did not diminish to the background level between the re-entry of the occupants to the office. The same was consistent for the radon concentration. The study shows how ventilation methods and small changes in occupant work strategy may influence the contaminant concentration within a test zone.

Effects of Preoperative Oral Carbohydrates on Recovery After Laparoscopic Cholecystectomy: A Meta-analysis of Randomized Controlled Trials.

PURPOSE: The objective of this meta-analysis was to evaluate the efficacy of administering preoperative oral carbohydrates (CHO) compared to a control treatment in improving postoperative recovery outcomes for patients undergoing laparoscopic cholecystectomy (LC). DESIGN: A meta-analysis of randomized controlled trials. METHODS: Through systematic searches in PubMed, Embase, and the Cochrane Library, randomized controlled trials focusing on preoperative oral carbohydrates for patients undergoing LC were collected. Data analysis was conducted using the Revman 5.3 software. FINDINGS: The meta-analysis incorporated 19 randomized studies, with a total of 1,568 participants. Meta-analysis results indicated that patients receiving CHO reported notably lower postoperative pain compared to those fasting (P = .006) or on placebo (P = .003). Furthermore, a significant reduction in preoperative hunger was observed in the CHO group compared to the controls (P = .002). A notable difference was also identified in the postoperative Homeostasis Model Assessment-IR changes between the CHO and control groups (P = .02). No significant variations were observed in thirst, postoperative nausea and vomiting, insulin level alterations, glucose level changes, duration of hospital stay, or recovery quality. CONCLUSIONS: Preoperative oral carbohydrates may alleviate hunger and pain, and attenuate postoperative insulin resistance more effectively than either overnight fasting or placebo in patients undergoing LC.

Assessing the multidimensional comfort of earplugs in virtual industrial noise environments.

Earplugs' comfort is primarily evaluated through cost-effective laboratory evaluations, yet these evaluations often inadequately capture the multidimensional comfort aspects due to design limitations that do not replicate real-world conditions. This paper introduces a novel laboratory method for comprehensive assessment of the multidimensional comfort aspects of earplugs, combining questionnaire-based evaluations and objective perceptual tests within virtual industrial sound environments replicating in-situ noise exposure. Objective perceptual results confirm that the sound environment affect participants' ability to detect alarms in a noisy environment and comprehend speech-in-noise while wearing earplugs. Subjective questionnaire results reveal that the earplugs family has an effect on the primary attributes of the acoustical, physical and functional comfort's dimension. Participants reported the physical dimension as the most important factor they take into account when evaluating earplugs' comfort. The functional dimension was considered the second most important factor by the participants, followed by the psychological dimension, and the acoustical dimension.

The effect on back pain, anxiety, and comfort levels of an elevated supine position and back support applied to patients undergoing coronary angiography: A randomized controlled experimental study.

OBJECTIVES: To determine the effect of elevated supine position with back support on back pain, anxiety and comfort in patients undergoing coronary angiography. METHODS: This randomized-controlled, experimental study was conducted in the Coronary Intensive Care Unit between September 2021 and January 2022, with an intervention group of 51 patients and a control group of 53 patients. Data were collected using a patient information form, a visual analog scale, the anxiety state inventory and the immobilization comfort questionnaire. Following angiography, the intervention group received pillow support to the back and the bedhead was elevated to 30 degrees. Routine nursing care was applied to the control group. In both groups, the severity of back pain was measured at 0, 2, and 4 hours, and anxiety and comfort at 0 and 4 hours. RESULTS: The pain severity at 2 and 4 hours after the procedure was determined to be significantly lower in the intervention group than in the control group (p<0.001, p<0.001). At 4 hours, the anxiety levels were similar in both groups (p<0.05), and the comfort level was higher in the intervention group (p<0.001). The mean pain value was 6.003 points lower and the comfort level was 20.499 points higher in the intervention group than in the control group. CONCLUSION: The elevated supine position with back support was seen to reduce back pain, increase comfort, and did not change anxiety levels.Clinical Trials No: NCT05546216.

Implications of sedation during the use of noninvasive ventilation in children with acute respiratory failure (SEDANIV Study).

BACKGROUND: The objective of this study was to analyze the effects of sedation administration on clinical parameters, comfort status, intubation requirements, and the pediatric intensive care unit (PICU) length of stay (LOS) in children with acute respiratory failure (ARF) receiving noninvasive ventilation (NIV). METHODS: Thirteen PICUs in Spain participated in a prospective, multicenter, observational trial from January to December 2021. Children with ARF under the age of five who were receiving NIV were included. Clinical information and comfort levels were documented at the time of NIV initiation, as well as at 3, 6, 12, 24, and 48 h. The COMFORT-behavior (COMFORT-B) scale was used to assess the patients' level of comfort. NIV failure was considered to be a requirement for endotracheal intubation. RESULTS: A total of 457 patients were included, with a median age of 3.3 months (IQR 1.3-16.1). Two hundred and thirteen children (46.6%) received sedation (sedation group); these patients had a higher heart rate, higher COMFORT-B score, and lower SpO2/FiO2 ratio than did those who did not receive sedation (non-sedation group). A significantly greater improvement in the COMFORT-B score at 3, 6, 12, and 24 h, heart rate at 6 and 12 h, and SpO2/FiO2 ratio at 6 h was observed in the sedation group. Overall, the NIV success rate was 95.6%-intubation was required in 6.1% of the sedation group and in 2.9% of the other group (p = 0.092). Multivariate analysis revealed that the PRISM III score at NIV initiation (OR 1.408; 95% CI 1.230-1.611) and respiratory rate at 3 h (OR 1.043; 95% CI 1.009-1.079) were found to be independent predictors of NIV failure. The PICU LOS was correlated with weight, PRISM III score, respiratory rate at 12 h, SpO2 at 3 h, FiO2 at 12 h, NIV failure and NIV duration. Sedation use was not found to be independently related to NIV failure or to the PICU LOS. CONCLUSIONS: Sedation use may be useful in children with ARF treated with NIV, as it seems to improve clinical parameters and comfort status but may not increase the NIV failure rate or PICU LOS, even though sedated children were more severe at technique initiation in the present sample.

[Influence of Postoperative Diet Type and Regimen on Hospital Comfort
and Rehabilitation of Lung Cancer Patients].

BACKGROUND: A reasonable and standardized dietary plan and procedure can help patients recovering quickly from lung cancer surgery. The aim of this study is to optimize the diet plan and procedure mainly based on medium chain triglyceride (MCT) diet and explore its clinical advantages for postoperative lung cancer patients. METHODS: From October 2023 to December 2023, a total of 156 patients were collected, who underwent lung cancer surgery in Lung Cancer Center, West China Hospital of Sichuan University. The patients were randomized into MCT group (76 cases) and routine diet (RD) group (80 cases). Clinical symptoms, biochemical index, postoperative hospitalization time and cost, dietary satisfaction and hospitalization comfort between the two groups were analyzed. RESULTS: The mean anus exhausting time in MCT group [24.00 (9.75, 36.97) h] was significantly shorter than that in RD group [28.50 (24.00, 48.00) h] (P<0.001). And the incidence of dizziness (18.42%), nausea and vomiting (6.58%) in MCT group were remarkably lower than those in RD group (51.25%, 31.25%) (P<0.001). Hospitalization comfort score in MCT group [(16.74±1.70)] was significantly higher than that in RD group [(14.83±2.34)] (P=0.016). Meanwhile, the average hospitalization cost in MCT group [(39,701.82±8105.47)¥] showed an obvious decrease compared with RD group [(44,511.79±9593.19)¥] (P=0.007). CONCLUSIONS: Optimizing the dietary plan and procedure mainly based on MCT diet for postoperative lung cancer patients can help the recovery of gastrointestinal function and improve hospitalization comfort, which promoted overall postoperative rehabilitation of patients with lung cancer surgery.

Relationships Between Success Factors in Daily Disposable Multifocal Contact Lenses.

Purpose: To explore links between subjective comfort and vision in habitual multifocal soft contact lens (MFCL) wearers when refit with daily disposable MFCLs, to determine which factors are relevant for success with MFCLs and evaluate consistency between MFCLs of different designs. Patients and Methods: This work examined subjective measures in a randomised, participant masked, bilateral wear crossover study at five optometry practices. Fifty-eight habitual MFCL wearers wore stenfilcon A multifocal (stenA-MF; CooperVision Inc) and delefilcon A multifocal (delA-MF; Alcon) for two-weeks. Subjective ratings included satisfaction with comfort and vision and agreement questions. Results: Agreement with "I would like to wear this MFCL in the future" was taken to indicate success with each MFCL; agreement was significantly higher with stenA-MF. There was strong correlation between agreement responses for "I would like to wear this MFCL in the future" and "MFCL met my needs for vision" with both lenses (p<0.01). However, it was only with stenA-MF, which had higher agreement responses to both statements (p<0.05), that responses to these two statements correlated with satisfaction with end-of-day (EOD) comfort (p<0.01). These differences in correlations between the two lenses are seemingly driven by greater satisfaction with stenA-MF for near and intermediate vision (p<0.05). Conclusion: Subjective vision and comfort were only correlated when vision met the needs of most participants. Meeting participants' needs for vision correlated strongly with wanting to wear a MFCL. Results indicate that meeting vision needs is more important than meeting comfort needs when influencing whether presbyopic patients continue wearing MFCLs.

Research on ride comfort optimization of the vehicle considering the subframe.

When the vehicle is in motion, the elastic deformation of the flexible subframe significantly influences ride comfort. Therefore, it is crucial to investigate the impact of flexible subframes on vehicle ride comfort. In order to enhance the reliability and optimization efficiency of our research, this paper incorporates the concept of elastic deformation in the flexible subframe into the investigation of vehicle ride comfort, and proposes a multi-objective optimization approach to enhance the overall vehicle ride comfort. The vibration mathematical model elucidates how flexible subframes affect vehicle ride comfort and establishes a rigid-flexible coupling model for a specific vehicle with a flexible subframe to analyze the impact of its elastic deformation on vehicle ride comfort through simulation experiments. Subsequently, a radial basis function approximation model is established, and the multi-objective particle swarm optimization and non-dominated sorting genetic algorithm II algorithms are employed to conduct multi-objective optimization of the stiffness of the subframe bushing with the aim of enhancing vehicle ride comfort. The findings indicate that the flexible subframe has a significant impact on vehicle ride comfort. Specifically, on bump roads, peak values of vertical and longitudinal seat accelerations decrease while lateral seat acceleration increases. On random roads, peak values of longitudinal and lateral seat accelerations increase while vertical acceleration decreases. Furthermore, the stiffness of the subframe bushing optimized by the non-dominated sorting genetic algorithm II algorithm further enhances vehicle ride comfort and aligns more closely with the optimization requirements in this study.

Numerical computation of heat transfer, moisture transport and thermal comfort through walls of buildings made of concrete material in the city of Douala, Cameroon: An ab initio investigation.

The buildings of the city of Douala in Cameroon have been experiencing degradation for several decades due to the climate characterized by high humidity and oppressive heat. As a result, large grayish or black stains can be observed on these buildings. We sometimes witness the subsidence of the slab of the balconies, the cracking of the walls and the collapse of the buildings worn by the humidity. These damages are generally caused by infiltration and capillary rise. In addition, it has been demonstrated that people living in damp buildings are at risk of illnesses such as asthma and lung infections. Therefore, the novelty of this work is threefold: (i) it proposes for the very first time a numerical study of the transport of humidity and heat through the porous walls of buildings constructed with concrete material, the main construction material in the city of Douala; (ii) It was determined what level of indoor thermal comfort was appropriate for sleeping inside a real three-dimensional G+1 complex residential building constructed with concrete blocks; and (iii) Using the geographical coordinates, and time data, the sun radiation's direction of incidence was assessed throughout the simulation. The computation was performed using Comsol Multiphysics 6.0 software. The distributions of temperature, relative humidity as well as moisture level were presented at various periods. It appears from the results that face to this high humidity, the concrete material retains a large quantity of water for a considerable periods of time, which weakens the steel reinforcement of concrete which is corroded by rust. The computation of thermal comfort in the 3D building showed that the various rooms of the building were not comfortable during the night since temperature inside the building increased progressively due to diffusion of heat. In addition, the numerical solutions indicated that the energy stored within the walls diffused from the external walls to the internal walls during the night. It was also demonstrated that the walls of the building were warmer than the windows, doors and the roof at the computational times, which simply revealed a greater storage capacity of heat in the concrete blocks material. The findings highlighted that the temperature decreased rapidly in a thickness of 0.06 m of the concrete block during the nine days and this decrease was attenuated in the second part of the thickness of the concrete block (0.14 m).

Cancer Doesn't Know the Day of the Week: Temporal Trends in Day of Death.

Studies support the existence of psychosomatic phenomena that enable critically ill patients to postpone death until a specific event. We assessed for this effect in cancer by examining variability in deaths at the month and weekend levels using the National Center for Health Statistics database. We found that deaths from cancer were not uniformly distributed temporally. There was a relative 3.3% difference death rate between the peak on Saturday and nadir on Monday, and relative 10.2% difference in rate of death between the peak of deaths in January and nadir in February. The "weekend effect" could be present in 1 in 200 cancer deaths and the "holiday effect" in 1 in 100 cancer deaths. Temporal variation may reflect a small portion of patients are able to "hold on" for a limited amount of time. This uneven distribution of cancer deaths highlights the importance of improving communication and facilitating end-of-life discussions.

Evaluation of Prenatal Comfort, Sleep, and Quality of Life in Pregnant Women with Cholestasis: A Cross-Sectional Study.

BACKGROUND: Associated with adverse pregnancy outcomes, intrahepatic cholestasis of pregnancy is the most prevalent liver disease that women typically experience during pregnancy. This study aimed to evaluate prenatal comfort, sleep, and quality of life in pregnant women with cholestasis. METHODS: This cross-sectional study was implemented between November 2022 and June 2023 at Mardin Training and Research Hospital with 150 pregnant women who received a diagnosis of pregnancy-induced intrahepatic cholestasis and agreed to participate. The following tools were utilized to collect data: A personal information form exploring socio-demographic and obstetric characteristics of participants, the Prenatal Comfort Scale (PCS), the Pittsburgh Sleep Quality Index (PSQI), and the World Health Organization Quality of Life-Brief Form (WHOQOL-BREF). RESULTS: The mean age of participants was 27.79 ± 6.33 years. The mean PCS and PSQI scores were 61.20 ± 5.84 and 9.52 ± 3.02, respectively. The mean scores of "physical health, psychological health, social relationships, and environmental health" sub-dimensions in WHOQOL-BREF were 10.63 ± 2.18, 10.48 ± 2.10, 11.31 ± 3.28, and 11.27 ± 2.10, respectively. A significant difference was found for PSQI regarding hospitalization status and change in sleep quality variables (p = 0.025 and p = 0.035, respectively). CONCLUSIONS: Cholestasis of pregnancy creates problems such as pruritus, body image changes, hospitalization, and poor sleep quality in women. This study showed that pregnant women with cholestasis had low levels of sleep quality and quality of life, implying that cholestasis affects their sleep quality, prenatal comfort levels, and quality of life in general. In addition, it is seen that women with this problem do not want to fall pregnant again.

Thermal Energy Storage in Concrete by Encapsulation of a Nano-Additivated Phase Change Material in Lightweight Aggregates.

This work discusses the applicability of lightweight aggregate-encapsulated n-octadecane with 1.0 wt.% of Cu nanoparticles, for enhanced thermal comfort in buildings by providing thermal energy storage functionality to no-fines concrete. A straightforward two-step procedure (impregnation and occlusion) for the encapsulation of the nano-additivated phase change material in lightweight aggregates is presented. Encapsulation efficiencies of 30-40% are achieved. Phase change behavior is consistent across cycles. Cu nanoparticles provide nucleation points for phase change and increase the rate of progression of phase change fronts due to the enhancement in the effective thermal conductivity of n-octadecane. The effective thermal conductivity of the composites remains like that of regular lightweight aggregates and can still fulfil thermal insulation requirements. The thermal response of no-fines concrete blocks prepared with these new aggregates is also studied. Under artificial sunlight, with a standard 1000 W·m-2 irradiance and AM1.5G filter, concrete samples with the epoxy-coated aggregate-encapsulated n-octadecane-based dispersion of Cu nanoparticles (with a phase change material content below 8% of the total concrete mass) can effectively maintain a significant 5 °C difference between irradiated and non-irradiated sides of the block for ca. 30 min.

Exploring perceptions of inpatient hospital attire in children with cancer.

BACKGROUND: Attire bolsters identity, self-expression, and comfort. Hospital gowns are known to be distressing in adults. Attitudes of children with cancer toward hospital attire remain uninvestigated and may be a modifiable factor in overall well-being. METHODS: A 39-item mixed methods survey evaluated perceptions of patient attire in children with cancer. Children aged 7-18 years were recruited at an academic medical center. Data analysis included simple statistics and thematic analysis. RESULTS: Forty children with cancer receiving oncologic care participated. Participants' mean age was 12.4 (SD = 3.0, range = 7-17) years, and 25 (62%) were male. Quantitative data revealed 81% of participants preferred their own attire when admitted to the hospital, feeling more comfortable in such when well (91%) or sick (75%). They did not feel like they "must" wear a gown when admitted (60%) and did not want to be asked about preferred inpatient attire (63%). Thematic analysis revealed that children had strong negative views of gowns and preferred to wear their own attire in the hospital, which provided physical and emotional comfort. Children worried wearing their own clothing could impede their care. CONCLUSION: Children with cancer prefer wearing their own clothes in the hospital for physical and emotional comfort. They are willing to wear gowns for ease of care; however, they do not want to arbitrate when they need to make that choice. Providers may ease distress by considering a child's own clothes as default hospital attire with instructions for when a gown is necessary for good clinical care.