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Mil Med ; 184(Suppl 1): 318-321, 2019 03 01.
Article in English | MEDLINE | ID: mdl-30901407

ABSTRACT

Vital signs are included in the determination of shock secondary to hemorrhage; however, more granular predictors are needed. We hypothesized that fast Fourier transformation (FFT) would have a greater percent change after hemorrhage than heart rate (HR) or systolic blood pressure (SBP). Using a porcine model, nine 17 kg pigs were hemorrhaged 10% of their calculated blood volume. Peripheral venous pressure waveforms, HR and SBP were collected at baseline and after 10% blood loss. FFT was performed on the peripheral venous pressure waveforms and the peak between 1 and 3 hertz (f1) corresponded to HR. To normalize values for comparison, percent change was calculated for f1, SBP, and HR. The mean percent change for f1 was an 18.8% decrease; SBP was a 3.31% decrease; and HR was a 0.95% increase. Using analysis of variance, FFT at f1 demonstrates a statistically significant greater change than HR or SBP after loss of 10% of circulating blood volume (p = 0.0023). Further work is needed to determine if this could be used in field triage to guide resuscitation.


Subject(s)
Hemorrhage/physiopathology , Venous Pressure/physiology , Vital Signs/physiology , Animals , Blood Pressure/physiology , Disease Models, Animal , Heart Rate/physiology , Hemodynamics , Hemorrhage/diagnosis , ROC Curve , Swine
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