ABSTRACT
Introduction: Genital tuberculosis (GT) is an infection that can affect the female reproductive system, including the uterus, cervix, and ovaries. Objective: To perform a scientometric exploration to analyze the spatiotemporal trend, evolution, and emerging patterns of scholarly output on GT and female infertility. Methods: An observational, descriptive, retrospective study employing a scientometric methodology was carried out. Metadata from scholarly articles spanning the years 1990-2022 were extracted from the Web of Science. The metadata from the chosen articles, totaling 172 manuscripts, were exported on May 17, 2023, in plain text format, which will allow the analysis and integration of the data in the software used. Results: We found at 111 sources and found 172 documents on tuberculosis and female infertility. We observed an average annual growth rate of 7.46 %, and the average age of the documents was 10.4 years. The dual overlay map showed the distribution of scientific publications on tuberculosis and female infertility. Journals on the left side of the map are cited mainly in the journals on the right. We found that Clinical Infectious Diseases and Lancet journals condensed patterns and trends in 1995, while the Indian Journal of Tuberculosis did so in 1996. Dheda K., Joubert JJ., and Wang Y. were the authors who had India, Iran, and China as their main affiliation, respectively, and they mainly published their studies in the "American Journal of Respiratory and Critical Care Medicine" and "Tropical Doctor," among others. Conclusions: This bibliometric study examined different sources and found an average annual growth rate of 7.46 %. Each article received an average of 16.48 citations. Different collaborative networks between countries were observed. In addition, there was a steady growth in published research in the field of tuberculosis and female infertility.
ABSTRACT
Antecedentes: La tuberculosis genital y la endometritis tuberculosa es una forma de tuberculosis que continúa siendo frecuente en los países en desarrollo y habitualmente es secundaria a un foco primario pulmonar. Puede cursar de forma asintomática, o bien, producir síntomas como infertilidad primaria o secundaria, alteraciones menstruales o dolor pélvico crónico, entre otros. Caso clínico: Se presenta el caso de una paciente de 47 años en estudio por ginecología y urología por dolor pélvico crónico y sintomatología urinaria inespecífica de aproximadamente 6 meses de evolución. La ecografía transvaginal muestra contenido intracavitario escaso sugerente de piometra e imágenes trabeculares compatibles con sinequias uterinas. Mediante aspirado endometrial se extrae pus y muestra endometrial que se remite para estudio anatomopatológico. Tras el informe anatomopatológico que diagnostica inflamación crónica granulomatosa necrotizante, se solicita estudio por PCR y cultivo para micobacteriumm tuberculosis, siendo ambos positivos para el microorganismo. De este modo, se diagnosticó como endometritis tuberculosa sin existir afectación de otros órganos tras el estudio completo. Se realizó tratamiento con etambutol hidrocloruro, isoniacida, pirazinamida y rifampicina durante 2 meses y pirazinamida e isonicida durante 7 meses adicionales. Al final del tratamiento, la paciente mostraba clara mejoría de los síntomas y a la ecografía desaparición de la colección intracavitaria uterina.
Background: Genital tuberculosis and endometritis tuberculosa is a form of tuberculosis which remains prevalent in developing countries and is usually secondary to a pulmonary primary focus. It may be asymptomatic, or may produce symptoms such as primary or secondary infertility, menstrual disorders or chronic pelvic pain, among others. Clinical case: We present the case of a patient of 47-year who was studied by ginecology and urology for chronic pelvic pain and unspecific urinary symptoms since about 6 months. In transvaginal ultrasound pyometra and trabecular images compatible with uterine synechiae were observed. Endometrial samples were obtaining and sent for histopathologic examination which was informed of chronic necrotizing granulomatous inflammation. We asked for PCR and culture for tuberculosis micobacteriumm, both being positive for the microorganism. Thus, she was diagnosed of endometritis tuberculosa without involvement of other organs after complete study. She performed a treatment with ethambutol hydrochloride, isoniazid, rifampicin and pyrazinamide for 2 months and pyrazinamide and isoniazid for 7 months. At the end of treatment, the patient showed clear improvement of symptoms and disappearance of uterine intracavitary collection in the ultrasonographic study.
Subject(s)
Humans , Female , Middle Aged , Endometritis/diagnosis , Endometritis/drug therapy , Tuberculosis, Female Genital/diagnosis , Tuberculosis, Female Genital/drug therapy , Ethambutol/therapeutic use , Isoniazid/therapeutic use , Rifampin/therapeutic useABSTRACT
Se describe el caso clínico de un paciente de 31 años de edad (bisexual y exrecluso), con antecedentes de hipertensión arterial, atendido de forma ambulatoria en la consulta de Urología del Hospital Clinicoquirúrgico Universitario "Dr. Ambrosio Grillo Portuondo" de Santiago de Cuba, por presentar cuadros repetidos de orquiepididimitis, sin experimentar la mejoría deseada, a pesar del tratamiento con antibióticos. Al examen físico se detectó un tumor en la cabeza del epidídimo, de modo que se realizó la resección quirúrgica de este. El resultado del estudio anatomopatológico informó que se trataba de una epididimitis granulomatosa de causa tuberculosa. Teniendo en cuenta los antecedentes patológicos personales antes descritos, así como la valoración del colectivo de neumólogos se concluyó el caso como una tuberculosis extrapulmonar genital, para lo cual se indicó el tratamiento específico.
The case report of a 31-year-old patient (a bisexual and ex convict man) is described, with a history of hypertension, who was attended in the outpatient Urology service of "Dr. Ambrosio Grillo Portuondo" Clinical Surgical University Hospital from Santiago de Cuba, for presenting repeated clinical patterns of orchiepididimitis, without experiencing the expected improvement, in spite of the treatment with antibiotics. With the physical exam a tumor was detected in the head of the epididymis, so its surgical resection was carried out. The result of the pathological study confirmed that it was a granulomatous epididymitis of tuberculous cause. Keeping in mind the personal pathological history described, as well as the evaluation of the pneumologists, the case was concluded as an extrapulmonary genital tuberculosis, for which the specific treatment was indicated.
ABSTRACT
The authors report one case of genital tuberculosis in a 3, 5 years old pure breed Nelore cow. This animal was acquired with 45 days of gestation. The retal palpation showed a volumosus uterus, of hard consistency and thick wall. The necropsy showed the uterus to have a caseosus nodule, with calcification. Mycobacterium bovis was isolated.
Os autores relatam um caso de tuberculose genital em uma vaca Nelore, pura de origem, com 3,5 anos de idade. O animal em questão foi adquirido como gestante de 45 dias e por época do provável parto constatou-se, por palpação retal, um útero volumoso, de consistência dura e parede espessa. À necropsia verificou-se que o conteúdo uterino era um nódulo caseoso, com calcificação, que as culturas revelaram a presença de Mycobacterium bovis.
ABSTRACT
The authors report one case of genital tuberculosis in a 3, 5 years old pure breed Nelore cow. This animal was acquired with 45 days of gestation. The retal palpation showed a volumosus uterus, of hard consistency and thick wall. The necropsy showed the uterus to have a caseosus nodule, with calcification. Mycobacterium bovis was isolated.
Os autores relatam um caso de tuberculose genital em uma vaca Nelore, pura de origem, com 3,5 anos de idade. O animal em questão foi adquirido como gestante de 45 dias e por época do provável parto constatou-se, por palpação retal, um útero volumoso, de consistência dura e parede espessa. À necropsia verificou-se que o conteúdo uterino era um nódulo caseoso, com calcificação, que as culturas revelaram a presença de Mycobacterium bovis.