ABSTRACT
PURPOSE: To describe a patient with mesenchymal chondrosarcoma of the orbit, review clinical and imaging findings, and refine the differential diagnosis from other tumors of the orbit. METHODS: Interventional case report and literature review. RESULTS: A 21-year-old woman with a 6-month history of progressive proptosis presented with left-sided visual loss of recent onset. CT revealed a clearly outlined heterogeneous mass with calcified foci, whereas MRI showed an isointense signal to gray matter on T1- and T2-weighted images. The patient was diagnosed with mesenchymal chondrosarcoma of the orbit only after orbitotomy and subsequent histopathologic study. After surgery, she received adjuvant therapy with irradiation of the orbit. CONCLUSIONS: Mesenchymal chondrosarcoma is a rare malignant tumor of the orbit capable of mimicking several other lesions. Early diagnosis requires a high level of suspicion, particularly with regard to internally calcified lesions. The treatment of choice is complete surgical resection, or, when the tumor is not resectable or residual mass is present after surgery, chemotherapy and radiotherapy. Prognosis for patients with orbital mesenchymal chondrosarcoma is tentative at best, in part because of the rarity of the lesion.
Subject(s)
Chondrosarcoma, Mesenchymal/diagnosis , Orbital Neoplasms/diagnosis , Adult , Chondrosarcoma, Mesenchymal/radiotherapy , Chondrosarcoma, Mesenchymal/surgery , Diagnosis, Differential , Female , Follow-Up Studies , Humans , Magnetic Resonance Imaging , Ophthalmologic Surgical Procedures/methods , Orbital Neoplasms/radiotherapy , Orbital Neoplasms/surgery , Radiotherapy, Adjuvant , Tomography, X-Ray ComputedABSTRACT
Presentamos tres casos de pacientes en los cuales se diagnosticaron tumores mesenquimales de diferente tipo, dos de ellos benignos y uno maligno. Las manifestaciones clínicas en cada caso fueron variables y el manejo en todos fue quirúrgico. Se revisa la literatura
Subject(s)
Female , Male , Adult , Middle Aged , Chondrosarcoma, Mesenchymal , Gastrointestinal Neoplasms , Chondrosarcoma, Mesenchymal/diagnosis , Chondrosarcoma, Mesenchymal/surgery , Gastrointestinal Neoplasms/diagnosis , Gastrointestinal Neoplasms/surgeryABSTRACT
Os autores relatam o caso de um paciente, portador de condrosarcoma mesenquial localizado na fossa posterior, que se estendia através do foramem magno até a segunda vértebra cervical. O condrosarcoma mesenquimal é um tumor raro que se origina de células multipotenciais do mesênquima embrionário. Este paciente foi submetido a ressecçäo microcirúrgica, com a remoçäo aparentemente total da neoplasia e reversäo temporária do quadro neurológico