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1.
Orphanet J Rare Dis ; 19(1): 253, 2024 Jul 04.
Article in English | MEDLINE | ID: mdl-38965635

ABSTRACT

INTRODUCTION: Eating, drinking and swallowing difficulties are commonly reported morbidities for individuals born with OA/TOF. This study aimed to determine the nature and prevalence of eating, drinking and oro-pharyngeal swallowing difficulties reported in this population. METHOD: A systematic review and meta-proportional analysis were conducted (PROSPERO: CRD42020207263). MEDLINE, EMBASE, CINAHL, Pubmed, Scopus, Web of Science databases and grey literature were searched. Quantitative and qualitative data were extracted relating to swallow impairment, use of mealtime adaptations and eating and drinking-related quality of life. Quantitative data were summarised using narrative and meta-proportional analysis methods. Qualitative data were synthesised using a meta-aggregation approach. Where quantitative and qualitative data described the same phenomenon, a convergent segregated approach was used to synthesise data. RESULTS: Sixty-five studies were included. Six oro-pharyngeal swallow characteristics were identified, and pooled prevalence calculated: aspiration (24%), laryngeal penetration (6%), oral stage dysfunction (11%), pharyngeal residue (13%), nasal regurgitation (7%), delayed swallow initiation (31%). Four patient-reported eating/drinking difficulties were identified, and pooled prevalence calculated: difficulty swallowing solids (45%), difficulty swallowing liquids (6%), odynophagia (30%), coughing when eating (38%). Three patient-reported mealtime adaptations were identified, and pooled prevalence calculated: need for water when eating (49%), eating slowly (37%), modifying textures (28%). Mixed methods synthesis of psychosocial impacts identified 34% of parents experienced mealtime anxiety and 25% report challenging mealtime behaviours reflected in five qualitative themes: fear and trauma associated with eating and drinking, isolation and a lack of support, being aware and grateful, support to cope and loss. CONCLUSIONS: Eating and drinking difficulties are common in adults and children with repaired OA/TOF. Oro-pharyngeal swallowing difficulties may be more prevalent than previously reported. Eating, drinking and swallowing difficulties can impact on psychological well-being and quality of life, for the individual and parents/family members. Long-term, multi-disciplinary follow-up is warranted.


Subject(s)
Deglutition Disorders , Esophageal Atresia , Humans , Deglutition Disorders/etiology , Esophageal Atresia/surgery , Tracheoesophageal Fistula/surgery , Quality of Life , Eating/physiology , Drinking/physiology
2.
Nutrients ; 16(13)2024 Jun 25.
Article in English | MEDLINE | ID: mdl-38999760

ABSTRACT

Toddlerhood (aged 13~36 months) is a period of dietary transition, with water intake being significantly influenced by parental feeding patterns, cultural traditions, and the availability of beverages and food. Nevertheless, given the lack of applicable data, it is challenging to guide and evaluate the water intake of toddlers in China. In this study, our objectives were to assess the daily total water intake (TWI), evaluate the consumption patterns of various beverages and food sources contributing to the TWI, determine the conformity of participants to the adequate intake (AI) recommendation of water released by the Chinese Nutrition Society, and analyze the various contributors to the daily total energy intake (TEI). The data for the assessment of water and dietary intake were obtained from the cross-sectional dietary intake survey of infants and young children (DSIYC, 2018-2019). A total of 1360 eligible toddlers were recruited in the analysis. The differences in related variables between two age groups were compared by Mann-Whitney U test and Chi-Square test. The potential correlation between water and energy intake was examined utilizing age-adjusted partial correlation. Toddlers consumed a median daily TWI of 1079 mL, with 670 mL (62.3%, r = 0.752) derived from beverages and 393 mL (37.7%, r = 0.716) from foods. Plain water was the primary beverage source, contributing 300 mL (52.2%, r = 0.823), followed by milk and milk derivatives (MMDs) at 291 mL (45.6%, r = 0.595). Notably, only 28.4% of toddlers managed to reach the recommended AI value. Among these, toddlers obtain more water from beverages than from foods. The median daily TEI of toddlers was 762 kcal, including 272 kcal from beverages (36.4%, r = 0.534) and 492 kcal from foods (63.6%, r = 0.894). Among these, the median daily energy intake from MMDs was 260 kcal, making up 94.6% of the energy intake from beverages (r = 0.959). As the pioneer survey on TWI of toddlers in China based on nationally representative data, attention to the quality and quantity of water intake and actions to better guide parents by both individuals and authorities are eagerly anticipated. Additionally, the revision of the reference value of TWI for Chinese toddlers is urgently required.


Subject(s)
Beverages , Drinking , Energy Intake , Humans , Infant , China , Male , Child, Preschool , Female , Cross-Sectional Studies , Nutrition Surveys , Water , Diet/statistics & numerical data , Diet Surveys , Feeding Behavior , Recommended Dietary Allowances , East Asian People
3.
Nutrients ; 16(13)2024 Jul 06.
Article in English | MEDLINE | ID: mdl-38999904

ABSTRACT

BACKGROUND: Ensuring adequate hydration is critical for breastfeeding women, yet their water consumption patterns and hydration status is poorly understood. This study investigates the water consumption patterns and estimated water balance among women, practicing exclusive, mixed, and no breastfeeding methods. METHODS: 529 healthy women completed the Nursing Water Balanced Questionnaire (N-WBQ). Participants were distributed across breastfeeding groups as follows: exclusive (39.7%), mixed (31.9%), and no breastfeeding (28.4%). RESULTS: Significant differences were noted in water consumption patterns among breastfeeding groups regarding intake from beverages (p < 0.001), juices (p = 0.019), coffee (p < 0.001), and milk (p = 0.015). Water intake from liquids, except for drinking water (p < 0.001), juices (p = 0.024) and coffee (p < 0.001) differed significantly among groups in women with adequate total water intake based on recommendation, with exclusive breastfeeding mothers prioritizing plain water over other beverages. Total water loss (p < 0.001) and estimated water balance (p < 0.001) significantly varied among breastfeeding groups, with exclusive breastfeeding mothers to exhibit the lowest water balance (-475.36 mL/day), indicating potential dehydration risk. Apart from plain water, water from foods, coffee and milk significantly contributed to positive water balance. CONCLUSIONS: Our findings highlight a risk of dehydration in this population, while water consumption patterns are influenced by breastfeeding method, likely affected by varying lactational demands and lifestyle factors. Further research to develop more accurate and individualized methods for assessing water balance in breastfeeding women is needed.


Subject(s)
Breast Feeding , Drinking , Humans , Female , Adult , Drinking/physiology , Water-Electrolyte Balance , Surveys and Questionnaires , Young Adult , Dehydration , Water , Beverages , Nutritional Status , Mothers
4.
BMC Anesthesiol ; 24(1): 231, 2024 Jul 10.
Article in English | MEDLINE | ID: mdl-38987679

ABSTRACT

BACKGROUND: Patients who are recovering from general anesthesia commonly exhibit symptoms such as dry lips, throat irritation, and thirst, prompting a desire to drink water in the post-anesthesia care unit (PACU). In this study, we aimed to evaluate the therapeutic effects and any potential complications of administering varying quantities of water to such patients. The primary objectives are to assess the safety and feasibility of early water intake after general anesthesia, specifically in the context of daytime surgery. METHODS: A total of 200 nongastrointestinal patients who underwent outpatient surgery were randomly assigned to four groups: Group A (drinking < 1 ml/kg), Group B (drinking 1-2 ml/kg), Group C (drinking > 2 ml/kg), and Group D (no water intake). We monitored changes in the assessment parameters before and after water consumption, as well as the incidence of post-drinking nausea and vomiting, and compared these outcomes among the four groups. RESULTS: Water intake led to a significant reduction in thirst, oropharyngeal discomfort, and pain scores and a notable increase in the gastric antrum motility index (MI), exhibiting statistical significance compared to the values before drinking (p < 0.05). Remarkably, higher water consumption correlated with enhanced gastrointestinal peristalsis. There was a significant difference in the antral MI among groups B, C, and A (p < 0.05). The occurrence of nausea and vomiting did not significantly differ among groups A, B, C, and D (p > 0.05). Early water consumption enhanced patient satisfaction with medical care, significantly varying from Group D (p < 0.05). CONCLUSION: Non-gastrointestinal surgical patients who passed pre-drinking water assessments post GA(general anesthesia)recovery could safely ingest moderate amounts of water in the PACU. Early water intake is both safe and feasible, effectively fostering swift postoperative recovery.


Subject(s)
Ambulatory Surgical Procedures , Anesthesia Recovery Period , Anesthesia, General , Drinking Water , Feasibility Studies , Humans , Anesthesia, General/methods , Female , Male , Middle Aged , Ambulatory Surgical Procedures/methods , Drinking Water/administration & dosage , Adult , Drinking , Postoperative Nausea and Vomiting/epidemiology , Thirst/physiology , Aged
5.
Int Ophthalmol ; 44(1): 320, 2024 Jul 08.
Article in English | MEDLINE | ID: mdl-38977648

ABSTRACT

PURPOSE: To evaluate the effects of a water drinking test (WDT) on the intraocular pressure (IOP) and vascular density of the optic nerve head and macula in healthy individuals and those with primary open glaucoma using optical coherence tomography angiography. METHODS: In this prospective comparative study, 30 healthy patients and 44 POAG subjects were divided into two groups. The study's outcome measures were the IOP and vessel density of the optic nerve and macular area. After ingesting 1000 ml of water in 5 min, the effect of the WDT on the IOP and the vascular density of the macular area and optic nerve head were measured at baseline and then 20, 40, and 60 min later at intervals of 20 min. RESULTS: The initial IOP in the healthy and glaucomatous eye groups was comparable (15.94 ± 2.6 and 16.87 ± 4.21 mmHg, respectively, P = 0.506). The IOP of both groups peaked at 40' measurements. POAG eyes had significantly higher IOP elevation (4.34 ± 0.30 vs. 2.24 ± 0.30 mmHg, P < 0.001). The glaucomatous eyes had lower radial peripapillary capillary (RPC) and whole macular superficial capillary plexus (SCP) densities at baseline (48.55 ± 5.99 vs. 51.33 ± 3.75) and (48.92 ± 3.41 vs. 45.29 ± 5.29), respectively (P < 0.001). After the WDT, the change in vessel density between groups in the RPC, whole superficial, and deep capillary plexuses was insignificant (SCP and DCP of 0.66 and 0.70, respectively, P = 0.16). CONCLUSION: The WDT caused a significant IOP jump in both glaucomatous and healthy eyes, but generally, the alterations in the glaucomatous eyes were more pronounced. The changes in vascular density in the macula and optic nerve head were similar between the groups.


Subject(s)
Fluorescein Angiography , Glaucoma, Open-Angle , Intraocular Pressure , Macula Lutea , Optic Disk , Retinal Vessels , Tomography, Optical Coherence , Humans , Tomography, Optical Coherence/methods , Male , Female , Prospective Studies , Optic Disk/blood supply , Optic Disk/diagnostic imaging , Intraocular Pressure/physiology , Middle Aged , Retinal Vessels/diagnostic imaging , Retinal Vessels/pathology , Macula Lutea/blood supply , Macula Lutea/diagnostic imaging , Glaucoma, Open-Angle/physiopathology , Glaucoma, Open-Angle/diagnosis , Fluorescein Angiography/methods , Adult , Drinking/physiology , Fundus Oculi , Aged , Retinal Ganglion Cells/pathology
6.
Nutrients ; 16(14)2024 Jul 13.
Article in English | MEDLINE | ID: mdl-39064707

ABSTRACT

Adequate water intake is essential for human health. Sugary beverage taxes are a best buy policy to reduce obesity and diet-related non-communicable diseases. Food-based dietary guidelines (FBDGs) promote healthy dietary patterns. The study purpose was to evaluate national FBDGs for countries with sugary beverage tax legislation (2000-2023) to promote water and discourage sugary beverage consumption. We developed a coding framework to conduct a content analysis of FBDG documents, and used six indicators to identify messages and images to assign healthy hydration recommendation (HHR) scores from 0-12 to compare FBDGs across countries and six regions. Results showed 93 countries with sugary beverage tax legislation of which 58 countries (62%) had published FBDGs (1998-2023). Of 58 FBDGs reviewed, 48 (83%) had complementary recommendations that encouraged water and discouraged sugary beverages. Of 93 countries, 13 (14%) had the highest HHR scores (11-12); 22, (24%) had high HHR scores (9-10); 20 (21%) had medium HHR scores (4-8); 3 (3%) had low HHR scores (0-3); and 35 (38%) countries had no FBDGs. To reduce health risks for populations, governments must ensure policy coherence to optimize sugary beverage tax impacts by developing FBDGs that encourage water and discourage sugary beverages complementary to national policies.


Subject(s)
Nutrition Policy , Sugar-Sweetened Beverages , Taxes , Humans , Taxes/legislation & jurisprudence , Sugar-Sweetened Beverages/economics , Sugar-Sweetened Beverages/legislation & jurisprudence , Nutrition Policy/legislation & jurisprudence , Drinking , Beverages/economics , Global Health
7.
Animal ; 18(7): 101209, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38905777

ABSTRACT

Dairy cows may suffer thermal stress during the colder seasons especially due to their open-air housing systems. Free water temperature (FWT) and feed temperature (FT) are dependent on ambient temperature (AT) and can be critical for maintaining body and reticulorumen temperature (RT) in cold conditions. The objective of this study was to determine the effects of FWT and FT on RT fluctuations, and of AT on RT and drinking and eating behaviors in late-lactation cows during cold exposure. Data were collected from 16 multiparous lactating cows for four 6-d periods during the autumn and winter seasons. The cows (224 ± 36 days in milk; mean ± SD) had an average milk yield (MY) of 24.8 ± 4.97 kg/d and RT of 38.84 ± 0.163 °C. Daily average AT ranged from 4.38 to 17.25 °C. The effects of the temperature and amount of the ingested water or feed on RT change and recovery time, and the effect of the daily AT on RT, feed and water intake, and drinking, eating, and rumination behaviors were analyzed using the generalized additive mixed model framework. Reticulorumen temperature change and recovery time were affected by FWT (+0.0596 °C/°C and -1.27 min/°C, respectively), but not by FT. The amount of the ingested free water and feed affected RT change (-0.108 °C/kg drink size and -0.150 °C/kg meal size, respectively), and RT recovery time (+2.13 min/kg drink size and + 3.71 min/kg meal size, respectively). Colder AT decreased RT by 0.0151 °C/°C between 9.91 and 17.25 °C AT. Cows increased DM intake (DMI) by 0.365 kg/d per 1 °C drop in AT below 10.63 °C, but with no increase in MY. In fact, MY:DMI decreased by 0.0106/°C as AT dropped from 17.25 to 4.38 °C. Free water intake (FWI) was reduced by 0.0856 FWI:DMI/°C as AT decreased from 17.25 to 8.27 °C. Cold exposure influenced animal behavior with fewer drink and meal bouts (-0.432 and -0.290 bouts/d, respectively), larger drink sizes (+0.100 kg/bout), and shorter rumination time (-5.31 min/d) per 1 °C decrease in AT from 17.25 °C to 8.77, 12.53, 4.38, and 10.32 °C, respectively. In conclusion, exposure to low AT increased feed intake, reduced water intake, and changes in eating, drinking and rumination behaviors of dairy cows in late lactation. Additionally, the consequences of cold exposure on cows may be aggravated by ingestion of feed and free water at temperatures lower than the body, potentially impacting feed efficiency due to the extra energetic cost of thermoregulation.


Subject(s)
Cold Temperature , Drinking , Feeding Behavior , Lactation , Seasons , Animals , Cattle/physiology , Female , Lactation/physiology , Drinking/physiology , Feeding Behavior/physiology , Temperature , Dairying , Rumen/physiology , Drinking Behavior/physiology
8.
Sultan Qaboos Univ Med J ; 24(2): 279-282, 2024 May.
Article in English | MEDLINE | ID: mdl-38828239

ABSTRACT

Peri-ictal water drinking (PIWD) is a rare vegetative manifestation of temporal lobe epilepsy without a definite lateralisation value. We report a case of PIWD in a 22-year-old Omani male patient with post-concussion syndrome and epilepsy presented to a tertiary care hospital in Muscat, Oman, in 2021 for evaluation of paroxysmal events. His behaviour of PIWD was misinterpreted by his family until characterised in the epilepsy-monitoring unit as a manifestation of epilepsy that was treated medically. To the best of the authors' knowledge, this is the second reported case in the region.


Subject(s)
Epilepsy, Temporal Lobe , Humans , Male , Oman , Young Adult , Epilepsy, Temporal Lobe/physiopathology , Drinking/physiology , Sclerosis , Electroencephalography/methods , Hippocampal Sclerosis
9.
Nutrients ; 16(11)2024 May 21.
Article in English | MEDLINE | ID: mdl-38892475

ABSTRACT

The association of hydration knowledge and health habits with hydration status and fluid intake is rarely examined. We sought to determine whether knowledge or physical health behaviors predict physiological hydration status and fluid intake. Ninety-six participants (59 female; 27 ± 10 year) completed the previously validated hydration survey. Participants then recorded total fluids consumed (TFC), collected urine, and tracked void frequency for 24 h. Hydration status was assessed via 24 h urine specific gravity (USG) and osmolality (Uosm). Health behaviors included self-reported physical activity, BMI, smoking, alcoholic drinking, and sleep status. TFC was significantly correlated with 24 h USG (r = -0.390; p < 0.001), Uosm (r = -0.486; p < 0.001), total urine volume (r = 0.675; p < 0.001), and void frequency (r = 0.518; p < 0.001). Hydration knowledge was not correlated with 24 h USG (r = 0.085; p = 0.420), Uosm (r = 0.087; p = 0.419), urine total volume (r = 0.019; p = 0.857), void frequency (r = 0.030; p = 0.771), or TFC (r = 0.027; p = 0.813). Hydration knowledge did not predict 24 h USG (LR+ = 1.10; LR- = 0.90), Uosm (LR+ = 0.81; LR- = 1.35), or TFC (LR+ = 1.00; LR- = 1.00). Health habits did not predict 24 h USG, Uosm, or TFC. In conclusion, self-reported 24 h diet and fluid log recording is comparable to hydration status verification via 24 h urine collection. Hydration knowledge and health habits are not related to, or predictive of, hydration status.


Subject(s)
Drinking , Health Behavior , Health Knowledge, Attitudes, Practice , Organism Hydration Status , Humans , Female , Male , Adult , Drinking/physiology , Organism Hydration Status/physiology , Young Adult , Specific Gravity , Dehydration/urine , Dehydration/physiopathology , Osmolar Concentration , Surveys and Questionnaires , Exercise/physiology , Water-Electrolyte Balance/physiology , Self Report
10.
Nutrients ; 16(11)2024 May 21.
Article in English | MEDLINE | ID: mdl-38892476

ABSTRACT

BACKGROUND: Evidence on the association between environmental factors and fluid intake behavior remains limited. The current study aims to explore seasonal variations in fluid intake behaviors among young adults in China. METHODS: A prospective cohort of 79 healthy young adults (43 males and 36 females) aged 19-21 in Hebei, China, was assessed for fluid intake behaviors for four seasons. For each assessment, the participants' anthropometric measurements were collected. Temperature and humidity on survey days were measured. Participants' total drinking fluid (TDF) was recorded using a self-administrative 7 d, 24 h fluid intake questionnaire. To calculate water from food (WFF), we weighed all foods consumed by participants. Duplicates of consumed food samples were collected to measure the water content via the drying method. RESULTS: The mean total water intake (TWI) was 2761 ± 881, 2551 ± 845, 2210 ± 551, and 1989 ± 579 for spring, summer, fall, and winter, respectively (F(2.37) = 42.29, p < 0.001). The volume and proportion of TWI from TDF and WFF varied across the four seasons. The volume of WFF in spring (1361 ± 281, F(2.61) = 17.21, p < 0.001) and TDF in summer (1218 ± 502, F(2.62) = 9.36, p < 0.001) was among the highest, while participants' fluid intake behaviors in spring and summer were less distinct than the other pairwise comparisons. A moderate association was found between outdoor temperature and TDF (r = 0.53, p < 0.01). Different general estimating equations suggested that gender, seasonality, outdoor temperature, differences in indoor and outdoor temperature, and mean temperature were independent factors of TDF. An interactive effect was found for gender and temperature, showing that the expected TDF of males may increase more as the temperature climbs. CONCLUSIONS: Gender, seasonality, and air temperature could significantly affect fluid intake behaviors, including the amount and type of fluid intake. However, the independent effect of BMI and humidity remains unclear.


Subject(s)
Drinking , Seasons , Humans , Male , Female , Young Adult , China , Prospective Studies , Drinking/physiology , Drinking Behavior , Temperature , Surveys and Questionnaires , Humidity
11.
Nutrients ; 16(11)2024 May 26.
Article in English | MEDLINE | ID: mdl-38892559

ABSTRACT

OBJECTIVE: Both short and long sleep durations are associated with decreased kidney function; however, few studies have examined the relationship between sleep, hydration status, and plain water intake. This study aimed to assess the relationship between sleep quality, hydration status, and plain water intake in pregnant women. METHODS: A cross-sectional study method was used to collect data from 380 pregnant women with regular examinations at the hospital between May 2019 and February 2021. RESULTS: There were statistically significant differences in daily plain water intake (x2 = 14.118, p = 0.001), PSQI score (x2 = 77.708, p < 0.001), sleep duration (x2 = 67.569, p > 0.001), subjective sleep quality (x2 = 67.441, p = 0.001), time to fall asleep (x2 = 64.782, p < 001), sleep disorders (x2 = 70.853, p < 0.001), and daytime dysfunction (x2 = 38.441, p < 0.001) among different hydration status groups. Ordinal logistic regression results indicated that the intake of plain water ≥1500 mL/d (OR = 0.40, 95% CI = 0.24~0.67), good subjective sleep quality (OR = 0.15, 95% CI = 0.07~0.32), short time to fall asleep (OR = 0.32, 95% CI = 0.14~0.70), 8 h of sleep (OR = 0.06, 95% CI = 0.02~0.17), 6-7 h of sleep (OR = 0.19, 95% CI = 0.07~0.54), no sleep disturbance (OR = 0.31, 95% CI = 0.11~0.89), and high sleep efficiency (OR = 0.46, 95% CI = 0.03~0.79) were factors that were correlated with optimal hydration status. Sleep duration and daytime dysfunction partially mediated the effect of plain water intake on hydration status. The mediating effect of sleep duration was -0.036, accounting for 14.006% of the overall effect. The mediating effect of daytime dysfunction was -0.024, accounting for 9.459% of the overall effect. CONCLUSION: The hydration status in pregnant women may be affected by daily plain water intake and sleep quality.


Subject(s)
Drinking , Sleep Quality , Humans , Female , Cross-Sectional Studies , Pregnancy , China/epidemiology , Adult , Drinking/physiology , Organism Hydration Status , Sleep Wake Disorders/epidemiology , Young Adult , Pregnant Women , Sleep/physiology
12.
Nutrients ; 16(11)2024 May 26.
Article in English | MEDLINE | ID: mdl-38892558

ABSTRACT

Adequate hydration is essential for good health, and an individual's hydration status is determined by the quantity and type of ingested fluids. The aim of the present study was to determine the hydration status of school-age children and evaluate changes in the type and quantity of consumed beverages between 2018 and 2023. The study was conducted in two stages between 2018 and 2023, and a total of 1030 fully completed questionnaires were returned by the children and their parents. A comparison of the parents' responses regarding factors that affect beverage choices revealed that beverage composition was more significant for the parents in 2023 than in 2018, whereas health-promoting properties were significant for only less than 30% of the respondents. Taste preferences were important for both the parents and the children, and they were the main criterion in the choice of beverages in both 2018 and 2023. In turn, advertising was an important factor for children, and the percentage of children who were guided by advertising in their choice of beverages increased from 52.1% in 2018 to 58.5% in 2023 (p < 0.05). Daily fluid intake from beverages in children aged 11-13 years generally does not meet recommended intakes. Low fluid intake can negatively affect children's hydration status and bodily functions. Taste preferences and advertising were correlated with a higher intake of carbonated and non-carbonated sugar-sweetened beverages (SSBs) and dairy beverages. The percentage of children who bought drinks independently and had access to SSBs increased significantly during the analyzed period. Obtain results indicate that nutrition education programs are needed to teach adolescents to make healthy drink choices, limit their consumption of SSBs and EDs, and promote regular intake of natural mineral water and non-sweetened dairy beverages.


Subject(s)
Beverages , Choice Behavior , Humans , Child , Poland , Adolescent , Beverages/statistics & numerical data , Female , Male , Surveys and Questionnaires , Food Preferences , Drinking , Parents/psychology , Organism Hydration Status , Taste
13.
Neuropharmacology ; 256: 110009, 2024 Sep 15.
Article in English | MEDLINE | ID: mdl-38823577

ABSTRACT

Water is critical for survival and thirst is a powerful way of ensuring that fluid levels remain in balance. Overconsumption, however, can have deleterious effects, therefore optimization requires a need to balance the drive for water with the satiation of that water drive. This review will highlight our current understanding of how thirst is both generated and quenched, with particular focus on the roles of angiotensin II, glucagon like-peptide 1, and estradiol in turning on and off the thirst drive. Our understanding of the roles these bioregulators play has benefited from modern behavioral analyses, which have improved the time resolution of intake measures, allowing for attention to the details of the patterns within a bout of intake. This has led to behavioral interpretation in ways that are helpful in understanding the many controls of water intake and has expanded our understanding beyond the dichotomy that something which increases water intake is simply a "stimulator" while something that decreases water intake is simply a "satiety" factor. Synthesizing the available information, we describe a framework in which thirst is driven directly by perturbations in fluid intake and indirectly modified by several bioregulators. This allows us to better highlight areas that are in need of additional attention to form a more comprehensive understanding of how the system transitions between states of thirst and satiety.


Subject(s)
Drinking , Thirst , Thirst/physiology , Humans , Animals , Drinking/physiology , Glucagon-Like Peptide 1/metabolism , Angiotensin II/metabolism , Angiotensin II/physiology , Estradiol/metabolism , Satiation/physiology
14.
Nutrients ; 16(11)2024 May 30.
Article in English | MEDLINE | ID: mdl-38892642

ABSTRACT

Despite decades of literature on (de)hydration in healthy individuals, many unanswered questions remain. To outline research and policy priorities, it is fundamental to recognize the literature trends on (de)hydration and identify current research gaps, which herein we aimed to pinpoint. From a representative sample of 180 (de)hydration studies with 4350 individuals, we found that research is mainly limited to small-scale laboratory-based sample sizes, with high variability in demographics (sex, age, and level of competition); to non-ecological (highly simulated and controlled) conditions; and with a focus on recreationally active male adults (e.g., Tier 1, non-athletes). The laboratory-simulated environments are limiting factors underpinning the need to better translate scientific research into field studies. Although, consistently, dehydration is defined as the loss of 2% of body weight, the hydration status is estimated using a very heterogeneous range of parameters. Water is the most researched hydration fluid, followed by alcoholic beverages with added carbohydrates (CHO). The current research still overlooks beverages supplemented with proteins, amino acids (AA), and glycerol. Future research should invest more effort in "real-world" studies with larger and more heterogeneous cohorts, exploring the entire available spectrum of fluids while addressing hydration outcomes more harmoniously.


Subject(s)
Dehydration , Humans , Dehydration/prevention & control , Male , Female , Adult , Water-Electrolyte Balance , Drinking/physiology
15.
Physiol Behav ; 283: 114601, 2024 Sep 01.
Article in English | MEDLINE | ID: mdl-38838800

ABSTRACT

AIM: The hypothesis of this study is to determine the effects of intracerebroventricular (icv) prokineticin 2 infusion on food consumption and body weight and to elucidate whether it has effects on energy expenditure via the hypothalamus-pituitary-thyroid (HPT) axis in adipose tissue. MATERIAL AND METHODS: A total of 40 rats were used in the study and 4 groups were established: Control, Sham, Prokineticin 1.5 and Prokineticin 4.5 (n=10). Except for the Control group, rats were treated intracerebroventricularly via osmotic minipumps, the Sham group was infused with aCSF (vehicle), and the Prokineticin 1.5 and Prokineticin 4.5 groups were infused with 1.5 nMol and 4.5 nMol prokineticin 2, respectively. Food and water consumption and body weight were monitored during 7-day infusion in all groups. At the end of the infusion, the rats were decapitated and serum TSH, fT4 and fT3 levels were determined by ELISA. In addition, PGC-1α and UCP1 gene expression levels in white adipose tissue (WAT) and brown adipose tissue (BAT), TRH from rat hypothalamic tissue were determined by real-time PCR. RESULTS: Icv prokineticin 2 (4.5 nMol) infusion had no effect on water consumption but reduced daily food consumption and body weight (p<0.05). Icv prokineticin 2 (4.5 nMol) infusion significantly increased serum TSH, fT4 and fT3 levels when compared to Control and Sham groups (p<0.05). Also, icv prokineticin 2 (4.5 nMol) infusion increased the expression of TRH in the hypothalamus tissue and expression of PGC-1α UCP1 in the WAT and BAT (p<0.05). CONCLUSION: Icv prokineticin 2 (4.5 nMol) infusion may suppress food consumption via its receptors in the hypothalamus and reduce body weight by stimulating energy expenditure and thermogenesis in adipose tissue through the HPT axis.


Subject(s)
Body Weight , Eating , Energy Metabolism , Gastrointestinal Hormones , Infusions, Intraventricular , Thyroid Gland , Animals , Energy Metabolism/drug effects , Energy Metabolism/physiology , Male , Body Weight/drug effects , Eating/drug effects , Eating/physiology , Thyroid Gland/drug effects , Thyroid Gland/metabolism , Rats , Gastrointestinal Hormones/metabolism , Gastrointestinal Hormones/administration & dosage , Uncoupling Protein 1/metabolism , Hypothalamo-Hypophyseal System/drug effects , Hypothalamo-Hypophyseal System/metabolism , Neuropeptides/metabolism , Neuropeptides/administration & dosage , Thyrotropin/blood , Thyrotropin/metabolism , Adipose Tissue, Brown/metabolism , Adipose Tissue, Brown/drug effects , Thyroxine/blood , Thyroxine/administration & dosage , Drinking/drug effects , Triiodothyronine/administration & dosage , Triiodothyronine/blood , Triiodothyronine/pharmacology , Rats, Wistar , Hypothalamus/metabolism , Hypothalamus/drug effects , Adipose Tissue, White/metabolism , Adipose Tissue, White/drug effects
16.
J Agromedicine ; 29(3): 477-485, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38704610

ABSTRACT

OBJECTIVE: To improve water access while working and contribute to fewer heat-related illnesses (HRI), backpack hydration systems were provided to over 200 farmworkers to use during the 2022 growing season. Acceptability of the water intake intervention was assessed among farmworkers in eastern North Carolina, USA. METHODS: With a pre-established community-university partnership, the acceptability of the intervention was assessed using a cross-sectional survey. The backpack brand selected included a 3-liter water bladder and attached drinking hose. Data analysis included descriptive and correlation statistics. RESULTS: Among 47 male, migrant farmworkers, most (90%) reported the hydration backpack to be acceptable or completely acceptable to workplace fluid intake. Most (53%) reported using the backpack some of the time, compared to 28% who used it often. The participants reported an average of 4.8 (SD 2.2) liters of water intake from the backpack on a typical workday. Most reported the backpack improved the quantity and frequency of their water consumption. CONCLUSION: This study was an important first step in implementation of hydration backpack systems as an HRI-preventative intervention among farmworkers. Future interventional studies could assess the efficacy of the backpacks on health outcomes, including incidence of dehydration and symptoms of HRI.


Subject(s)
Farmers , Humans , Male , Farmers/statistics & numerical data , Adult , North Carolina , Cross-Sectional Studies , Middle Aged , Transients and Migrants/statistics & numerical data , Drinking , Heat Stress Disorders/prevention & control , Young Adult
17.
Med J Malaysia ; 79(3): 331-336, 2024 May.
Article in English | MEDLINE | ID: mdl-38817067

ABSTRACT

INTRODUCTION: Hypospadias is a congenital malformation of the urethral meatus in the ventral penis that requires surgery. Fibre and fluid intake can accelerate the healing process, act as an anti-inflammatory and support the success of surgery. Based on hypospadias objective scoring evaluation (HOSE) scoring, this study aims to determine whether a high-fibre diet and adequate fluid intake affect the outcome of hypospadias surgery. MATERIALS AND METHODS: This analytic observational study used a case-control study design on 104 post-operative hypospadias patients at Ulin and Siaga Hospital Banjarmasin from 2018 to 2023 with quota sampling. Data were collected using personal data forms with hypospadias objective scoring evaluation (HOSE) and semi-quantitativefood frequency questionnaire (SQ-FFQ), which were analysed using a multinomial logistic regression test. RESULTS: Patients with less-fibre-intake had a 99.10% lower chance of having an excellent surgical outcome than patients with moderate-fibre-intake (Adjusted Odds Ratio, Adj. OR: 0.009, 95% Confidence Intervals; 95%CI: 0.000, 0.249), and it was statistically significant. The study did not find any association between fluid intake and surgical outcome, this could be due to the fact that most of the patient had good fluid intake. CONCLUSION: The study found that high fibre intake increases the success of hypospadia surgery.


Subject(s)
Dietary Fiber , Hypospadias , Humans , Hypospadias/surgery , Male , Case-Control Studies , Dietary Fiber/administration & dosage , Child, Preschool , Child , Treatment Outcome , Drinking , Infant , Urologic Surgical Procedures, Male/methods
18.
Nutrients ; 16(9)2024 Apr 29.
Article in English | MEDLINE | ID: mdl-38732589

ABSTRACT

Sweat rate and electrolyte losses have a large inter-individual variability. A personalized approach to hydration can overcome this issue to meet an individual's needs. This study aimed to investigate the effects of a personalized hydration strategy (PHS) on fluid balance and intermittent exercise performance. Twelve participants conducted 11 laboratory visits including a VO2max test and two 5-day trial arms under normothermic (NOR) or hyperthermic (HYP) environmental conditions. Each arm began with three days of familiarization exercise followed by two random exercise trials with either a PHS or a control (CON). Then, participants crossed over to the second arm for: NOR+PHS, NOR+CON, HYP+PHS, or HYP+CON. The PHS was prescribed according to the participants' fluid and sweat sodium losses. CON drank ad libitum of commercially-available electrolyte solution. Exercise trials consisted of two phases: (1) 45 min constant workload; (2) high-intensity intermittent exercise (HIIT) until exhaustion. Fluids were only provided in phase 1. PHS had a significantly greater fluid intake (HYP+PHS: 831.7 ± 166.4 g; NOR+PHS: 734.2 ± 144.9 g) compared to CON (HYP+CON: 369.8 ± 221.7 g; NOR+CON: 272.3 ± 143.0 g), regardless of environmental conditions (p < 0.001). HYP+CON produced the lowest sweat sodium concentration (56.2 ± 9.0 mmol/L) compared to other trials (p < 0.001). HYP+PHS had a slower elevated thirst perception and a longer HIIT (765 ± 452 s) compared to HYP+CON (548 ± 283 s, p = 0.04). Thus, PHS reinforces fluid intake and successfully optimizes hydration status, regardless of environmental conditions. PHS may be or is an important factor in preventing negative physiological consequences during high-intensity exercise in the heat.


Subject(s)
Exercise , Hot Temperature , Water-Electrolyte Balance , Adult , Female , Humans , Male , Cross-Over Studies , Dehydration/prevention & control , Dehydration/therapy , Drinking/physiology , Exercise/physiology , Sweat/chemistry , Sweating/physiology , Water-Electrolyte Balance/physiology
19.
BMC Nephrol ; 25(1): 183, 2024 May 28.
Article in English | MEDLINE | ID: mdl-38807063

ABSTRACT

BACKGROUND: Structured Problem Solving (SPS) is a patient-centered approach to promoting behavior change that relies on productive collaboration between coaches and participants and reinforces participant autonomy. We aimed to describe the design, implementation, and assessment of SPS in the multicenter Prevention of Urinary Stones with Hydration (PUSH) randomized trial. METHODS: In the PUSH trial, individuals with a history of urinary stone disease and low urine output were randomized to control versus a multicomponent intervention including SPS that was designed to promote fluid consumption and thereby prevent recurrent stones. We provide details specifically about training and fidelity assessment of the SPS coaches. We report on implementation experiences related to SPS during the initial conduct of the trial. RESULTS: With training and fidelity assessment, coaches in the PUSH trial applied SPS to help participants overcome barriers to fluid consumption. In some cases, coaches faced implementation barriers such as variable participant engagement that required tailoring their work with specific participants. The coaches also faced challenges including balancing rapport with problem solving, and role clarity for the coaches. CONCLUSIONS: We adapted SPS to the setting of kidney stone prevention and overcame challenges in implementation, such as variable patient engagement. Tools from the PUSH trial may be useful to apply to other health behavior change settings in nephrology and other areas of clinical care. TRIAL REGISTRATION: ClinicalTrials.gov Identifier NCT03244189.


Subject(s)
Drinking , Problem Solving , Urinary Calculi , Humans , Urinary Calculi/prevention & control , Male , Female , Drinking Behavior
20.
Sensors (Basel) ; 24(10)2024 May 11.
Article in English | MEDLINE | ID: mdl-38793909

ABSTRACT

Constipation is a common gastrointestinal disorder that impairs quality of life. Evaluating bowel motility via traditional methods, such as MRI and radiography, is expensive and inconvenient. Bowel sound (BS) analysis has been proposed as an alternative, with BS-time-domain acoustic features (BSTDAFs) being effective for evaluating bowel motility via several food and drink consumption tests. However, the effect of BSTDAFs before drink consumption on those after drink consumption is yet to be investigated. This study used BS-based stimulus-response plots (BSSRPs) to investigate this effect on 20 participants who underwent drinking tests. A strong negative correlation was observed between the number of BSs per minute before carbonated water consumption and the ratio of that before and after carbonated water consumption. However, a similar trend was not observed when the participants drank cold water. These findings suggest that when carbonated water is drunk, bowel motility before ingestion affects motor response to ingestion. This study provides a non-invasive BS-based approach for evaluating motor response to food and drink, offering a new research window for investigators in this field.


Subject(s)
Drinking , Gastrointestinal Motility , Humans , Drinking/physiology , Male , Gastrointestinal Motility/physiology , Female , Adult , Young Adult , Constipation/physiopathology , Healthy Volunteers , Carbonated Water
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