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1.
J Thorac Cardiovasc Surg ; 163(1): 2-12.e7, 2022 Jan.
Article in English | MEDLINE | ID: mdl-32624307

ABSTRACT

OBJECTIVE: The incidence of elderly patients with acute type A aortic dissection is increasing. A recent analysis of the International Registry of Acute Aortic Dissection failed to show a mortality benefit with surgery compared with medical management in octogenarians. Therefore, we compared our institutional outcomes of emergency surgery for acute type A aortic dissection in octogenarians versus septuagenarians to understand the outcomes of surgical intervention in elderly patients. METHODS: From 2002 to 2017, 70 octogenarians (aged ≥80 years) and 165 septuagenarians (70-79 years) underwent surgery for acute type A aortic dissection (N = 235, total). Quality of life was assessed by the RAND Short Form-36 quality of life survey. Midterm clinical and functional data were obtained retrospectively. RESULTS: At baseline, septuagenarians had a higher prevalence of diabetes (20.6% vs 5.7%, P = .01). The prevalence of cardiopulmonary resuscitation was 4.8% versus 10.0% (P = .24) in septuagenarians and octogenarians. The prevalence of cardiogenic shock was 18.2% versus 27.1% (P = .17). Thirty-day/in-hospital mortality was 21.2% versus 28.6% (P = .29). Multivariable logistic regression identified cardiogenic shock as an independent risk factor for in-hospital mortality (odds ratio, 10.07; 95% confidence interval, 2.30-44.03) in octogenarians. Survival at 5 years was 49.7% (42.1%-58.6%) versus 34.2% (23.9%-48.8%) in septuagenarians and octogenarians, respectively. Responses to the quality of life survey were no different between septuagenarians and octogenarians across all 8 quality of life categories. CONCLUSIONS: Clinical outcomes after surgery for acute type A aortic dissection are similar in octogenarians and septuagenarians. For discharged survivors, quality of life remains favorable and does not differ between the 2 groups.


Subject(s)
Aortic Aneurysm, Thoracic , Aortic Dissection , Emergency Treatment , Quality of Life , Shock, Cardiogenic , Vascular Surgical Procedures , Age Factors , Aged , Aged, 80 and over , Aortic Dissection/complications , Aortic Dissection/mortality , Aortic Dissection/psychology , Aortic Dissection/surgery , Aortic Aneurysm, Thoracic/complications , Aortic Aneurysm, Thoracic/mortality , Aortic Aneurysm, Thoracic/psychology , Aortic Aneurysm, Thoracic/surgery , Cardiopulmonary Resuscitation/methods , Cardiopulmonary Resuscitation/statistics & numerical data , Comorbidity , Emergency Treatment/adverse effects , Emergency Treatment/methods , Emergency Treatment/statistics & numerical data , Female , Hospital Mortality , Humans , Male , Outcome and Process Assessment, Health Care , Risk Factors , Shock, Cardiogenic/epidemiology , Shock, Cardiogenic/etiology , Survival Analysis , United States/epidemiology , Vascular Surgical Procedures/adverse effects , Vascular Surgical Procedures/methods
2.
J Surg Res ; 182(1): 11-6, 2013 Jun 01.
Article in English | MEDLINE | ID: mdl-22921919

ABSTRACT

BACKGROUND: Unplanned reoperations have been proposed as a quality indicator in surgery but have not been studied extensively, especially concerning risk factors. METHODS: This was a prospective cohort study in a third-level general surgery service. Data regarding patients operated on between July 2007 and February 2008 and followed up for 30 postoperative days were collected. Unplanned reoperations were the primary end point. The secondary end points were 30-d mortality and length of stay. A multivariate logistic regression analysis evaluated the hypothesis that patients operated on in emergency conditions had a greater chance of being reoperated on, after adjusting for relevant covariates. RESULTS: There was a 5.9% cumulative incidence of unplanned reoperations. Patients operated on in emergency conditions had a 1.79 crude relative risk (RR) (95% confidence interval [CI], 1.15-2.78) of reoperation. Reoperated patients' RR of mortality was 8.94 (95% CI, 6.11-13.07). The mean postoperative hospital stay was 3d for patients who were not reoperated on and 19d for those who were reoperated on (P=0.00001). The logistic regression model gave a 2.83 odds ratio (95% CI, 1.65-4.87) for reoperation on emergency patients when adjusted for age, gender, body mass index, American Society of Anesthesiology classification, intraoperative inotropic use, and operation complexity. CONCLUSIONS: Tertiary general surgery service patients had a significantly increased risk of being reoperated on if the initial surgery was an emergency surgery compared with elective surgery. Unplanned reoperations led to a significantly increased mortality risk and a longer postoperative hospital stay, which could be regarded as warning signs in the care of surgical patients.


Subject(s)
Emergency Treatment/adverse effects , General Surgery/statistics & numerical data , Postoperative Complications/epidemiology , Postoperative Complications/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Cohort Studies , Endpoint Determination , Female , Humans , Length of Stay , Logistic Models , Male , Middle Aged , Prospective Studies , Reoperation/mortality , Reoperation/statistics & numerical data , Risk Factors , Survival Rate , Young Adult
3.
Rev Bras Cir Cardiovasc ; 23(3): 336-43, 2008.
Article in English, Portuguese | MEDLINE | ID: mdl-19082321

ABSTRACT

OBJECTIVES: This study aims to verify the applicability of Ambler's risk score to patients who have undergone implantation of bovine pericardial bioprosthesis at the Instituto de Cardiologia do RGS/FCU. This study also aims to quantify the risk factors. METHODS: Retrospective study with 703 patients who had undergone implantation of bovine pericardial bioprosthesis between 1991 and 2005 at the Instituto de Cardiologia do RS. Aortic implant occurred in 392 patients, mitral in 250 and combined in 61. Primary outcome was hospital mortality. Characteristics used to estimate risk were: gender, age, body mass index (BMI), NYHA functional class, left ventricular ejection fraction, valvular lesions, systemic arterial hypertension, diabetes mellitus, renal function, cardiac rhythm, previous cardiac operations, and surgical priority. Univariate and multivariate logistic regression was used to quantify preponderant risk factors by the odds-ratio (OR). RESULTS: The mortality rate was 14.3%, which was higher than the estimated mortality rate (3%, according to Ambler's mean score of 6, (p<0.01)). Patients who died presented a mean score of 8.26, which was higher than the survivors' average score of 5.68. Characteristics of increased risk were emergency surgery (OR=10.87), dialysis (OR=6.10), and age higher than 80 years (OR=6.10). Our sample indicates an area under the ROC curve of 72.9% (accepted value > 70%). CONCLUSION: The mortality predicted in Ambler's score was not reproduced in the observed results. However, the ROC curve provides evidence that this model is applicable. Preponderant risk factors were individualizated.


Subject(s)
Aortic Valve Insufficiency/surgery , Bioprosthesis , Heart Valve Prosthesis Implantation/mortality , Models, Theoretical , Pericardium , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Animals , Aortic Valve Insufficiency/diagnosis , Aortic Valve Insufficiency/mortality , Brazil/epidemiology , Cattle , Dialysis/adverse effects , Emergency Treatment/adverse effects , Epidemiologic Methods , Female , Heart Valve Prosthesis Implantation/adverse effects , Humans , Male , Middle Aged , Reference Values , Risk Factors , Treatment Outcome , Young Adult
4.
Rev. bras. cir. cardiovasc ; Rev. bras. cir. cardiovasc;23(3): 336-343, jul.-set. 2008. ilus, tab, graf
Article in English, Portuguese | LILACS | ID: lil-500518

ABSTRACT

OBJETIVO: O estudo objetiva verificar aplicabilidade do escore de Ambler para pacientes que receberam implante bioprótese de pericárdio bovino no Instituto de Cardiologia do RGS/FUC e quantificar os fatores de risco. MÉTODOS: Estudo retrospectivo com 703 pacientes submetidos ao implante de bioprótese de pericárdio bovino entre 1991 e 2005, no Instituto de Cardiologia do RS. Em 392 pacientes, ocorreu implante aórtico, em 250, mitral e, em 61, combinado. Desfecho primário foi mortalidade hospitalar. As características estimativas do risco foram: idade, sexo, IMC, classe funcional (NYHA), fração de ejeção ventricular esquerda (FE), lesão valvar, hipertensão arterial sistêmica, diabete melito, função renal, ritmo cardíaco, cirurgia cardíaca prévia, revascularização miocárdica e/ou plastia tricúspide concomitante, caráter cirúrgico. Utilizada regressão logística uni e multivariada para quantificar fatores de risco preponderantes, pelo odds ratio (OR). RESULTADOS: A mortalidade observada foi de 14,3%, superior à prevista de valor 3% para escore médio 6 de Ambler, (p<0,01). Pacientes falecidos mostraram escore médio 8,26, superior ao dos sobreviventes, de 5,68. Características de maior risco foram cirurgia emergencial (OR=10,87), diálise (OR=6,10) e idade > 80 anos (OR=6,10). A área sob curva ROC para nossa amostra foi calculada em 72,9% (aceitável > 70%). CONCLUSÃO: A mortalidade prevista no escore de Ambler não é reproduzida no resultado observado, mas a curva ROC evidenciou que o modelo é aplicável. Fatores de risco preponderantes foram individualizados.


OBJETIVES: This study aims to verify the applicability of Ambler's risk score to patients who have undergone implantation of bovine pericardial bioprosthesis at the Instituto de Cardiologia do RGS/FCU. This study also aims to quantify the risk factors. METHODS: Retrospective study with 703 patients who had undergone implantation of bovine pericardial bioprosthesis between 1991 and 2005 at the Instituto de Cardiologia do RS. Aortic implant occurred in 392 patients, mitral in 250 and combined in 61. Primary outcome was hospital mortality. Characteristics used to estimate risk were: gender, age, body mass index (BMI), NYHA functional class, left ventricular ejection fraction, valvular lesions, systemic arterial hypertension, diabetes mellitus, renal function, cardiac rhythm, previous cardiac operations, and surgical priority. Univariate and multivariate logistic regression was used to quantify preponderant risk factors by the odds-ratio (OR). RESULTS: The mortality rate was 14.3%, which was higher than the estimated mortality rate (3%, according to Ambler's mean score of 6, (p<0.01)). Patients who died presented a mean score of 8.26, which was higher than the survivors' average score of 5.68. Characteristics of increased risk were emergency surgery (OR=10.87), dialysis (OR=6.10), and age higher than 80 years (OR=6.10). Our sample indicates an area under the ROC curve of 72.9% (accepted value > 70%). CONCLUSION: The mortality predicted in Ambler's score was not reproduced in the observed results. However, the ROC curve provides evidence that this model is applicable. Preponderant risk factors were individualizated.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Animals , Cattle , Female , Humans , Male , Middle Aged , Young Adult , Aortic Valve Insufficiency/surgery , Bioprosthesis , Heart Valve Prosthesis Implantation/mortality , Models, Theoretical , Pericardium , Age Factors , Aortic Valve Insufficiency/diagnosis , Aortic Valve Insufficiency/mortality , Brazil/epidemiology , Dialysis/adverse effects , Epidemiologic Methods , Emergency Treatment/adverse effects , Heart Valve Prosthesis Implantation/adverse effects , Reference Values , Risk Factors , Treatment Outcome , Young Adult
5.
Rev. Soc. Odontol. La Plata ; 21(38): 25-28, jul. 2008. ilus, tab
Article in Spanish | LILACS | ID: lil-514601

ABSTRACT

Las investigaciones realizadas sobre las profesiones asistenciales, particularmente las relacionadas con salud, evidencian un malestar subjetivo y tensión emocional en diversos grados, lo que motivó al estudio de las causas que generan dichas patologías en los profesionales de guardia odontológica de 24 hs. semanales. Se realiza una investigación a partir de encuestas de satisfacción personal, para evaluar los factores que provocan ansiedad y estrés en los profesionales odontólogos con actividad en 24 hs. de guardia semanal. Las encuestas serán autoadministradas, anónimas y dirigidas a los 11 profesionales del servicio de guardia del Hospital José Dueñas de la Ciudad de Buenos Aires.


Subject(s)
Stress, Psychological/epidemiology , Stress, Psychological/etiology , Dentists/psychology , Dental Service, Hospital/statistics & numerical data , Emergencies/psychology , Argentina , Health Care Surveys , Data Interpretation, Statistical , Emergency Treatment/adverse effects
6.
Arq Bras Cardiol ; 89(2): 113-8, 125-30, 2007 Aug.
Article in English, Portuguese | MEDLINE | ID: mdl-17874018

ABSTRACT

BACKGROUND: Identification of preoperative heart valve surgery risk factors aim to improve surgical outcomes with the possibility to offset conditions related to increased morbidity and mortality. OBJECTIVE: Intent of this study is to identify hospital risk factors in patients undergoing bovine pericardial bioprosthesis implantation. METHODS: Retrospective study including 703 consecutive patients who underwent implantation of at least one St. Jude Medical-Biocor bovine pericardial bioprosthesis between September 1991 and December 2005 at the Rio Grande do Sul Cardiology Institute; 392 were aortic, 250 were mitral and 61 were mitroaortic. Characteristics analyzed were gender, age, body mass index, NYHA (New York Heart Association) functional class, ejection fraction, valve lesions, systemic hypertension, diabetes mellitus, kidney function, arrhythmias, prior heart surgery, coronary artery bypass graft, tricuspid valve surgery and elective, urgent or emergency surgery. Main outcome was in-hospital mortality. Relationship between risk factors and in-hospital mortality was analyzed using logistic regression. RESULTS: Were 101 (14.3%) in-hospital deaths. Characteristics with significant relationship to increased mortality were female gender (p<0.001), age over 70 years (p=0.004), atrial fibrillation (p=0.006), diabetes mellitus (p=0.043), creatinine > 2.4 mg/dl (p=0.004), functional class IV (p<0.001), mitral valve lesion (p<0.001), previous heart surgery (p=0.005), tricuspid valve surgery (p<0.001) and emergency surgery (p<0.001). CONCLUSION: Mortality rate observed is accepted by literature and is justifiable due to the high prevalence of risk factors, showing an increased significance level for female gender, age above 70, functional class IV, tricuspid valve repairs and emergency surgery. Offsetting these factors could contribute to reduced in-hospital mortality for valve surgery.


Subject(s)
Bioprosthesis , Heart Valve Prosthesis Implantation/mortality , Hospital Mortality , Adolescent , Adult , Age Factors , Aged , Aged, 80 and over , Animals , Atrial Fibrillation/complications , Cattle , Diabetes Complications , Emergency Treatment/adverse effects , Epidemiologic Methods , Female , Heart Valve Prosthesis Implantation/adverse effects , Heart Valves/surgery , Humans , Male , Middle Aged , Sex Factors
7.
Arq. bras. cardiol ; Arq. bras. cardiol;89(2): 125-130, ago. 2007. tab
Article in Portuguese | LILACS | ID: lil-460777

ABSTRACT

FUNDAMENTO: Identificação de fatores de risco pré-operatórios na cirurgia cardíaca valvar visa melhor resultado cirúrgico pela possível neutralização de condições relacionadas com morbi-mortalidade aumentada. OBJETIVO: Este estudo objetiva identificar fatores de risco hospitalar em pacientes submetidos a implante de bioprótese de pericárdio bovino. MÉTODOS: Estudo retrospectivo incluindo 703 pacientes consecutivos submetidos a implante de pelo menos uma bioprótese de pericárdio bovino St. Jude Medical-Biocor® de setembro de 1991 a dezembro de 2005 no Instituto de Cardiologia do RS, sendo 392 aórticos, 250 mitrais e 61 mitro-aórticos. Analisadas as características sexo, idade, índice de massa corporal, classe funcional (New York Heart Association - NYHA), fração de ejeção, lesão valvar, hipertensão arterial sistêmica, diabete melito, função renal, arritmias cardíacas, cirurgia cardíaca prévia, revascularização miocárdica, plastia tricúspide e caráter eletivo, de urgência ou de emergência da cirurgia. Desfecho primordial foi mortalidade hospitalar. Utilizou-se regressão logística para examinar relação entre fatores de risco e mortalidade hospitalar. RESULTADOS: Ocorreram 101 (14,3 por cento) óbitos hospitalares. Características significativamente relacionadas à mortalidade aumentada foram sexo feminino (p<0,001), idade superior a 70 anos (p=0,004), fibrilação atrial (p=0,006), diabete melito (p=0,043), creatinina > 2,4mg/dl (p=0,004), classe funcional IV (p<0,001), lesão valvar mitral (p<0,001), cirurgia cardíaca prévia (p=0,005), plastia tricúspide (p<0,001) e caráter cirúrgico emergencial (p<0,001). CONCLUSÃO: Observada mortalidade aceita pela literatura, justificável pela prevalência de alguns fatores de risco, tendo elevado nível de significância sexo feminino, idade superior a 70 anos, classe funcional IV, plastia tricúspide e caráter emergencial. A possível neutralização destes poderá contribuir para redução da mortalidade hospitalar...


BACKGROUND: Identification of preoperative heart valve surgery risk factors aim to improve surgical outcomes with the possibility to offset conditions related to increased morbidity and mortality. OBJECTIVE: Intent of this study is to identify hospital risk factors in patients undergoing bovine pericardial bioprosthesis implantation. METHODS: Retrospective study including 703 consecutive patients who underwent implantation of at least one St. Jude Medical-Biocor™ bovine pericardial bioprosthesis between September 1991 and December 2005 at the Rio Grande do Sul Cardiology Institute; 392 were aortic, 250 were mitral and 61 were mitroaortic. Characteristics analyzed were gender, age, body mass index, NYHA (New York Heart Association) functional class, ejection fraction, valve lesions, systemic hypertension, diabetes mellitus, kidney function, arrhythmias, prior heart surgery, coronary artery bypass graft, tricuspid valve surgery and elective, urgent or emergency surgery. Main outcome was in-hospital mortality. Relationship between risk factors and in-hospital mortality was analyzed using logistic regression. RESULTS: Were 101 (14.3 percent) in-hospital deaths. Characteristics with significant relationship to increased mortality were female gender (p<0.001), age over 70 years (p=0.004), atrial fibrillation (p=0.006), diabetes mellitus (p=0.043), creatinine > 2.4mg/dl (p=0.004), functional class IV (p<0.001), mitral valve lesion (p<0.001), previous heart surgery (p=0.005), tricuspid valve surgery (p<0.001) and emergency surgery (p<0.001). CONCLUSION: Mortality rate observed is accepted by literature and is justifiable due to the high prevalence of risk factors, showing an increased significance level for female gender, age above 70, functional class IV, tricuspid valve repairs and emergency surgery. Offsetting these factors could contribute to reduced in-hospital mortality for valve surgery.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Animals , Cattle , Female , Humans , Male , Middle Aged , Bioprosthesis , Hospital Mortality , Heart Valve Prosthesis Implantation/mortality , Age Factors , Atrial Fibrillation/complications , Diabetes Complications , Epidemiologic Methods , Emergency Treatment/adverse effects , Heart Valve Prosthesis Implantation/adverse effects , Heart Valves/surgery , Sex Factors
8.
Prensa méd. argent ; 92(4): 228-235, 2005. ilus
Article in Spanish | BINACIS | ID: bin-401

ABSTRACT

Se define como falla aguda de la herida quirúrgica a la separación brusca de los bordes del cierre laparotómico durante el postoperatorio inmediato, que puede incluir algunos o la totalidad de los planos parietales. El objetivo del trabajo es evaluar la incidencia de esta entidad en un Servicio de Cirugía General, analizar los factores predisponentes y desencadenantes y exponer la conducta terapéutica y hacer algunas consideraciones respecto de la profilaxis de esta complicación


Subject(s)
Humans , Surgical Wound Dehiscence/classification , Surgical Wound Dehiscence/complications , Surgical Wound Dehiscence/diagnosis , Surgical Wound Dehiscence/surgery , Morbidity , Emergency Treatment/adverse effects , Surgical Wound Infection/prevention & control , Abdomen/surgery
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