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1.
Article in English | MEDLINE | ID: mdl-39219482

ABSTRACT

The definitive management of combined aortic arch and descending aortic pathologies such as aneurysms and dissections is either a single or staged operation associated with high morbidity and mortality. Stroke, kidney dysfunction, coagulopathy and high blood transfusion requirements are all affiliated with hypothermic circulatory arrest and prolonged cardiopulmonary bypass times. Considering the perilous nature of these operations, the authors describe a step-by-step zone 2 arch replacement as a staged frozen elephant trunk procedure, which provides an adequate landing zone for a later-placed endovascular stent yet maintains a short cardiopulmonary bypass time and no circulatory arrest.


Subject(s)
Aorta, Thoracic , Aortic Aneurysm, Thoracic , Aortic Dissection , Blood Vessel Prosthesis Implantation , Humans , Aorta, Thoracic/surgery , Aortic Aneurysm, Thoracic/surgery , Blood Vessel Prosthesis Implantation/methods , Blood Vessel Prosthesis Implantation/adverse effects , Aortic Dissection/surgery , Endovascular Procedures/methods , Male , Stents , Cardiopulmonary Bypass/methods , Blood Vessel Prosthesis , Female , Middle Aged
3.
BMJ Case Rep ; 17(8)2024 Aug 14.
Article in English | MEDLINE | ID: mdl-39142846

ABSTRACT

Pseudoaneurysm of the lateral perforating branch of the peroneal artery is exceedingly rare. To our knowledge, eight cases are described in the current literature, with five occurring as a result of trauma and the remainder being iatrogenic. We present a pseudoaneurysm of the lateral perforating peroneal artery in a professional athlete following an inversion-plantarflexion injury of the ankle. He described persistent pain and fluctuant swelling to the lateral aspect of the right ankle with sudden onset of increased pain and swelling 10 days after the initial injury. Arterial duplex identified a pseudoaneurysm of the right lateral perforating peroneal artery. Endovascular coil embolisation of the aneurysm resulted in almost immediate improvement in symptoms. The patient has since regained full function of the affected ankle. This case report highlights the necessity for clinicians to maintain a high index of suspicion in order to promptly investigate and appropriately manage this pathology.


Subject(s)
Aneurysm, False , Ankle Injuries , Embolization, Therapeutic , Humans , Aneurysm, False/therapy , Aneurysm, False/etiology , Aneurysm, False/diagnostic imaging , Embolization, Therapeutic/methods , Male , Ankle Injuries/complications , Ankle Injuries/therapy , Adult , Endovascular Procedures/methods
4.
Khirurgiia (Mosk) ; (8): 108-117, 2024.
Article in Russian | MEDLINE | ID: mdl-39140952

ABSTRACT

Trauma is one of the leading causes of disability and mortality in working-age population. Abdominal injuries comprise 20-30% of traumas. Uncontrolled bleeding is the main cause of death in 30-40% of patients. Among abdominal organs, spleen is most often damaged due to fragile structure and subcostal localization. In the last two decades, therapeutic management has become preferable in patients with abdominal trauma and stable hemodynamic parameters. In addition to clinical examination, standard laboratory tests and ultrasound, as well as contrast-enhanced CT of the abdomen should be included in diagnostic algorithm to identify all traumatic injuries and assess severity of abdominal damage. Development of interventional radiological technologies improved preservation of damaged organs. Endovascular embolization can be performed selectively according to indications (leakage, false aneurysm, arteriovenous anastomosis) and considered for severe damage to the liver and spleen, hemoperitoneum or severe polytrauma. Embolization is essential in complex treatment of traumatic vascular injuries of parenchymal abdominal organs. We reviewed modern principles and methods of intra-arterial embolization for the treatment of patients with traumatic injuries of the liver and spleen.


Subject(s)
Abdominal Injuries , Embolization, Therapeutic , Endovascular Procedures , Spleen , Wounds, Nonpenetrating , Humans , Abdominal Injuries/therapy , Abdominal Injuries/diagnosis , Wounds, Nonpenetrating/therapy , Embolization, Therapeutic/methods , Spleen/injuries , Spleen/blood supply , Endovascular Procedures/methods , Liver/injuries , Liver/blood supply , Liver/diagnostic imaging
5.
Neurosurg Rev ; 47(1): 432, 2024 Aug 14.
Article in English | MEDLINE | ID: mdl-39141147

ABSTRACT

Cerebral aneurysm rupture, the predominant cause of non-traumatic subarachnoid hemorrhage, underscores the need for effective treatment and early detection methods. A study in Neurosurgical Review compared microsurgical clipping to endovascular therapy in 130 patients with middle cerebral artery (MCA) aneurysms, finding significantly fewer serious adverse events (SAEs) and neurological complications in the endovascular group. This suggests endovascular therapy's superiority in safety and reducing complications for MCA aneurysm patients. Furthermore, a systematic review and meta-analysis assessed the diagnostic accuracy of AI algorithms in detecting cerebral aneurysms, revealing a high sensitivity but notable false-positive rates, indicating AI's potential while highlighting the need for further validation. Machine learning algorithms also showed promise in predicting cerebral aneurysm rupture risk, demonstrating reasonable sensitivity and specificity. Additionally, AI-based radiomics models are advancing rapidly, offering enhanced predictive accuracy and personalized treatment planning by analyzing imaging data to identify features indicative of aneurysm conditions. Collectively, these findings emphasize the advantages of endovascular therapy for MCA aneurysms and the emerging role of AI and machine learning in improving early detection and personalized management of cerebral aneurysms.


Subject(s)
Intracranial Aneurysm , Machine Learning , Humans , Intracranial Aneurysm/surgery , Intracranial Aneurysm/diagnosis , Endovascular Procedures/methods , Aneurysm, Ruptured/surgery , Artificial Intelligence , Neurosurgical Procedures/methods
6.
Eur J Radiol ; 178: 111653, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39094465

ABSTRACT

OBJECTIVES: This study aimed to assess the predictive performance of radiomics derived from computed tomography (CT) images of thrombus regions in predicting the risk of intracranial hemorrhage (ICH) following endovascular thrombectomy (EVT). MATERIALS AND METHODS: This retrospective multicenter study included 336 patients who underwent admission CT and EVT for acute anterior-circulation large vessel occlusion between December 2018 and December 2023. Follow-up imaging was performed 24 h post-procedure to evaluate the occurrence of ICH. 230 patients from centers A and B were randomly allocated into training and test groups in a 7:3 ratio, while the remaining 106 patients from center C comprised the validation cohort. Radiologists manually segmenting the thrombus on CT images, and the perithrombus region was defined by expanding the initial region of interest (ROI). A total of 428 radiomics features were extracted from both intrathrombus and perithrombus regions on CT images. The Mann-Whitney U test was used for feature selection, and least absolute shrinkage and selection operator (LASSO) regression was employed for model development, followed by validation using a 5-fold cross-validation approach. Model performance was assessed using the area under the curve (AUC) of the receiver operating characteristic (ROC). RESULTS: Among the eligible patients, 128 (38.1 %) experienced ICH after EVT. The combined model exhibited superior performance in the training cohort (AUC: 0.913, 95 % CI: 0.861-0.965), test cohort (AUC: 0.868, 95 % CI: 0.775-0.962), and validation cohort (AUC: 0.850, 95 % CI: 0.768-0.912). Notably, in the validation group, both the perithrombus and combined models demonstrated higher predictive accuracy compared to the intrathrombus model (0.837 vs. 0.684, p = 0.02; AUC: 0.850 vs. 0.684, p = 0.01). CONCLUSIONS: Radiomics features derived from the perithrombus region significantly enhance the prediction of ICH after EVT, providing valuable insights for optimizing post-procedural clinical decisions. CLINICAL RELEVANCE STATEMENT: This study highlights the importance of radiomics extracted from intrathrombus and perithrombus region in predicting intracranial hemorrhagefollowing endovascular thrombectomy, which can aid in improving patient outcomes.


Subject(s)
Endovascular Procedures , Intracranial Hemorrhages , Radiomics , Thrombectomy , Thrombosis , Tomography, X-Ray Computed , Humans , Endovascular Procedures/adverse effects , Endovascular Procedures/methods , Intracranial Hemorrhages/diagnostic imaging , Intracranial Hemorrhages/etiology , Predictive Value of Tests , Retrospective Studies , Risk Assessment/methods , Thrombectomy/adverse effects , Thrombectomy/methods , Thrombosis/diagnostic imaging , Thrombosis/surgery , Tomography, X-Ray Computed/methods
7.
Dtsch Med Wochenschr ; 149(17): 1002-1008, 2024 Aug.
Article in German | MEDLINE | ID: mdl-39146746

ABSTRACT

The rate of vascular recanalizations in CLTI is increasing worldwide. Safety and efficacy of surgical versus endovascular treatment in CLTI patients was investigated in 2 prospective randomized trials with contrasting results. The BEST-CLI trial randomized 1830 patients with CLTI, the Bypass versus Angioplasty for Severe Ischaemia of the Leg (BASIL-2) trial included 345 patients with CLTI. Best-CLI evaluated outcome events as the primary endpoint, which includes major reinterventions in addition to major amputations and death. Only half of the CLTI patients received a crural intervention or surgery. There were no differences in major amputations or death. After a median follow-up (FU) of 2,7 years, the surgery group showed significantly better results compared to the endovascular group, due to fewer re-interventions. BASIL-2 used amputation-free survival as the primary outcome and only included patients with lower leg lesions. After a median FU of 40 months, endovascular therapy was found to be superior. The extremely high mortality rate was remarkable in both studies. The BEST-CLI study represents CLTI patients only to a limited degree, whereas the BASIL-2 study presents the treatment of CLTI patients with below-the-knee-lesions quite well. Both studies confirm that patients with CLTI should be treated in specialized centers that offer both crural surgery and endovascular therapy. Cardiovascular risk factor management must play a more important role in reducing the high mortality associated with CLTI.


Subject(s)
Amputation, Surgical , Humans , Chronic Limb-Threatening Ischemia/surgery , Chronic Limb-Threatening Ischemia/therapy , Ischemia/therapy , Endovascular Procedures/methods , Male , Treatment Outcome , Aged , Female , Middle Aged
8.
Mil Med ; 189(Supplement_3): 284-290, 2024 Aug 19.
Article in English | MEDLINE | ID: mdl-39160869

ABSTRACT

INTRODUCTION: Retrograde Endovascular Balloon Occlusion of the Aorta (REBOA) is an effective management for the transient responder, but the ischemic consequences of complete aortic occlusion currently limit its use. Multiple DoD-funded preclinical studies have clearly demonstrated that partial REBOA reduces distal ischemia to potentially extend safe occlusion times, while still providing effective temporization of noncompressible torso hemorrhage. Early versions of REBOA devices were designed to completely occlude the aorta and had little ability to provide partial occlusion. Recently, a new REBOA device (pREBOA-PRO) was designed specifically to allow for partial occlusion, with the hypothesis that this may reduce the complications of aortic occlusion and extend safe occlusion times while maintaining the benefits on cardiac and cerebrovascular circulation as well as reductions in resuscitation requirements. MATERIALS AND METHODS: To ascertain the impact of a new purpose-built partial REBOA device on the extension of safe occlusion time, the Partial REBOA Outcomes Multicenter ProspecTive (PROMPT) trial compared available data from the pREBOA-PRO with existing data from 200 clinical uses of pREBOA-PRO and available data in the AAST AORTA Registry were reviewed to design primary endpoints and clinical evidence for a prospective multi-center trial, the PROMPT Study. Together with the endpoints identified in preclinical studies of partial REBOA, primary endpoints for the PROMPT study were identified and power analyses were conducted to determine the target patient enrollment goals. RESULTS: Results from the clinical implementation of partial REBOA at a single trauma center were used to conduct the initial power analysis for the primary endpoint of Acute Kidney Injury (AKI) after prolonged occlusion. The rate of AKI after complete REBOA was 55% (12/20) compared to 33% (4/12) after partial REBOA (Madurska et al., 2021). With an alpha of 0.05 and power (ß) of 0.8, the projected sample size for comparison on a dichotomous outcome is 85 patients for the assessment of AKI. Initial power and endpoint analyses have been confirmed and extended with the ongoing analysis of partial and complete REBOA reported in the AORTA database. These analyses confirm preclinical findings which show that compared to complete REBOA, partial REBOA is associated with extended occlusion time in zone 1 (complete: 31 min vs. partial: 45 min, P = 0.003), lower rates of AKI after zone 1 occlusion (complete: 33% vs. partial: 19%, P = 0.05) and reduced resuscitation requirements (e.g., 25% reduction in pRBC administration: complete: 18 units vs. partial: 13 units, P = 0.02). CONCLUSIONS: The DoD-funded PROMPT study of partial REBOA will provide prospective observational clinical data on patients being treated with pREBOA-PRO. Outcomes will be stratified based on partial or complete occlusion to address whether partial REBOA has additional clinical benefits over complete REBOA, such as decreased distal ischemia, extension of safe occlusion time, improved hemodynamics during transition to and from occlusion, and reduced interoperative bleeding and blood product use. The results from this study are expected to confirm previous data demonstrating reduction of ischemic sequalae, improved transition to reperfusion, and reduced resuscitative requirements compared to complete REBOA.


Subject(s)
Aorta , Balloon Occlusion , Humans , Balloon Occlusion/methods , Balloon Occlusion/standards , Balloon Occlusion/instrumentation , Balloon Occlusion/statistics & numerical data , Prospective Studies , Male , Female , Adult , Endovascular Procedures/methods , Endovascular Procedures/instrumentation , Middle Aged , Resuscitation/methods , Resuscitation/instrumentation , Resuscitation/standards , Resuscitation/statistics & numerical data , Hemorrhage/therapy , Hemorrhage/prevention & control , Treatment Outcome
9.
Br J Surg ; 111(8)2024 Aug 02.
Article in English | MEDLINE | ID: mdl-39162334

ABSTRACT

BACKGROUND: Surgical ligation and stripping (surgery) and endothermal ablation are both effective treatments for varicose veins, improving quality of life (QoL) up to 5 years. Few data are available on long-term outcomes. The aim of this study was to evaluate the outcomes 10 years after interventions in an RCT. Previously this RCT demonstrated that endothermal ablation is associated with superior postprocedural QoL, more rapid recovery, and lower rates of early clinical recurrence. This analysis reports outcomes at 10 years. METHODS: Patients with symptomatic varicose veins owing to unilateral great saphenous vein reflux were randomized to either surgery or endovenous laser ablation (EVLA). Outcomes at 10 years included clinical recurrence and QoL. RESULTS: Data were obtained for 206 of 280 patients (73.6%) at 10 years. Both groups retained significant QoL improvement compared with pretreatment levels (Aberdeen Varicose Vein Questionnaire (AVVQ), Short Form 36 (SF-36®), and EQ-5D™; P < 0.001). Clinical disease progression from baseline was observed in only 10.7% of patients. The clinical recurrence rate was lower in the EVLA group (37 versus 59%; P = 0.005). The number needed to treat with EVLA to avoid one clinical recurrence within 10 years was five. This was associated with significantly higher (better) generic QoL scores with EVLA in several SF-36® domains, including bodily pain (median 84 (i.q.r. 51-100) versus 62 (41-84); P = 0.009) and general health (77 (62-87) versus 67 (52-82); P = 0.017). AVVQ scores in the EVLA group were also lower (better) (3.1 (0-7.7) versus 6.3 (0.7-13.3); P = 0.029). CONCLUSION: Both surgery and endothermal ablation are effective treatments for varicose veins at 10 years, with durable improvement in QoL and a very low rate of disease progression. However, endothermal ablation was associated with superior clinical and QoL outcomes. Registration number: NCT00759434 (http://www.clinicaltrials.gov).


Subject(s)
Laser Therapy , Quality of Life , Recurrence , Saphenous Vein , Varicose Veins , Humans , Varicose Veins/surgery , Saphenous Vein/surgery , Female , Male , Middle Aged , Laser Therapy/methods , Treatment Outcome , Adult , Aged , Endovascular Procedures/methods , Follow-Up Studies
10.
BMJ Case Rep ; 17(8)2024 Aug 07.
Article in English | MEDLINE | ID: mdl-39117366

ABSTRACT

Parvimonas micra is a gram-positive anaerobic coccus typically found in the human oral cavity, upper respiratory tract and gastrointestinal system. It occasionally causes intra-abdominal abscesses, spondylodiscitis and other infections. There are very few case reports on mycotic aneurysm related to P. micra We describe a rare case of P. micra orbital cellulitis complicated with meningitis, cerebral venous thrombosis and internal carotid artery mycotic aneurysm, which was successfully treated with the combination of endovascular therapy and antibiotics. Additionally, the patient received 6 months of anticoagulation therapy for cerebral venous thrombosis.


Subject(s)
Aneurysm, Infected , Anti-Bacterial Agents , Orbital Cellulitis , Humans , Orbital Cellulitis/microbiology , Orbital Cellulitis/complications , Anti-Bacterial Agents/therapeutic use , Aneurysm, Infected/complications , Gram-Positive Bacterial Infections/complications , Gram-Positive Bacterial Infections/drug therapy , Gram-Positive Bacterial Infections/diagnosis , Male , Firmicutes , Venous Thrombosis/complications , Venous Thrombosis/drug therapy , Anticoagulants/therapeutic use , Intracranial Thrombosis/complications , Intracranial Thrombosis/drug therapy , Endovascular Procedures/methods , Female
11.
BMJ Open ; 14(8): e087490, 2024 Aug 07.
Article in English | MEDLINE | ID: mdl-39117408

ABSTRACT

INTRODUCTION: Endovenous laser ablation (EVLA) is associated with an excellent outcome in the treatment of great saphenous vein (GSV) incompetence. However, the use of thermal ablation requires tumescent anaesthesia and is associated with a risk of thermal damage. Mechanochemical endovenous ablation (MOCA) is a non-thermal ablation (NTA) alternative, which combines mechanical endothelial damage with the infusion of a sclerosant liquid or foam. Tumescent anaesthesia is not required. Preliminary experiences with MOCA using the Clarivein device show less intraprocedural and postprocedural pain and a faster clinical improvement compared with EVLA. Flebogrif (Balton, Poland) is a relatively new MOCA device. To determine the role of MOCA using Flebogrif, a well-designed, randomised controlled clinical trial of sufficient sample size and follow-up time is required. In this article, we provide the study protocol for the REBORN trial, aiming to demonstrate that MOCA using Flebogrif is not inferior to EVLA for the outcome of anatomical success in the treatment of GSV incompetence. METHODS AND ANALYSIS: This multicentre, open-label, non-inferiority, observer-blinded, randomised controlled trial randomises patients who are diagnosed with GSV incompetence and aged 18-80 years between Flebogrif and EVLA. 310 patients in 3 participating centres (Northwest Clinics Alkmaar, Skin and Vein Clinic Oosterwal Alkmaar and Red Cross Hospital Beverwijk) will be included. The primary outcome is anatomical success at 12 months. Secondary outcomes are intraprocedural pain, operation time, technical success, postprocedural pain, safety, anatomical success during other follow-up moments, complications, clinical success, aesthetic result, disease-specific quality of life, reinterventions, anterior accessory saphenous vein reflux and neovascularisation. Patients will be followed up at 1 week, 1, 6, 12, 24 and 60 month(s) after treatment. ETHICS AND DISSEMINATION: The institutional review board (Medical Ethical Review Committee of the Vrije Universiteit Medical Center) approved this study on 17 May 2021 under case number 2020.0740. Written informed consent is obtained by the coordinating investigator from all participants prior to study enrolment. After completion of the trial, the results will be submitted to an international scientific journal for peer-reviewed publication. TRIAL REGISTRATION NUMBER: Overzicht van Medisch-wetenschappelijk Onderzoek in Nederland, NL-OMON25145, previously NL9527; Centrale Commissie Mensgebonden Onderzoek, NL74491.029.20.


Subject(s)
Endovascular Procedures , Laser Therapy , Saphenous Vein , Venous Insufficiency , Humans , Saphenous Vein/surgery , Venous Insufficiency/surgery , Laser Therapy/methods , Laser Therapy/adverse effects , Endovascular Procedures/methods , Equivalence Trials as Topic , Treatment Outcome , Multicenter Studies as Topic , Female , Adult , Sclerotherapy/methods , Sclerosing Solutions/therapeutic use , Sclerosing Solutions/administration & dosage , Male
12.
BMJ Open ; 14(8): e080560, 2024 Aug 07.
Article in English | MEDLINE | ID: mdl-39117410

ABSTRACT

INTRODUCTION: Endovascular therapy has emerged as a prominent strategy for managing femoropopliteal peripheral artery disease, offering acceptable safety and efficacy compared with open surgical bypass. Both paclitaxel-eluting stents and heparin-bonded covered stents have exhibited enhanced clinical outcomes compared with bare metal stents. However, there is currently a lack of level I evidence comparing the safety and efficacy of paclitaxel-eluting stents and heparin-bonded covered stents. Therefore, the primary objective of this study is to systematically evaluate the efficacy and safety outcomes of these two types of stents. METHODS AND ANALYSIS: The ELITE trial is a prospective, multicentre, parallel, randomised controlled trial. A total of 450 patients will be recruited. The primary endpoints of the study include primary patency at 1 year post-index procedure. ETHICS AND DISSEMINATION: Ethical approval for this study was obtained from the Ethics Committee of West China Hospital of Sichuan University (approval number: 2023-1186). The results will be submitted to a major clinical journal for peer review and publication. TRIAL REGISTRATION: ELITE trial was registered on 27 September 2023 in the Chinese Clinical Trials Registry (ChiCTR2300076236).


Subject(s)
Drug-Eluting Stents , Femoral Artery , Heparin , Peripheral Arterial Disease , Popliteal Artery , Humans , Heparin/administration & dosage , Heparin/therapeutic use , Peripheral Arterial Disease/therapy , Peripheral Arterial Disease/surgery , Popliteal Artery/surgery , Prospective Studies , Femoral Artery/surgery , China , Paclitaxel/administration & dosage , Paclitaxel/therapeutic use , Randomized Controlled Trials as Topic , Multicenter Studies as Topic , Treatment Outcome , Endovascular Procedures/methods , Male , Female , Stents , Vascular Patency
13.
Pediatr Pulmonol ; 59 Suppl 1: S115-S122, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39105344

ABSTRACT

Up to 90% of people with CF (pwCF) will have some form of hepatobiliary involvement. This manuscript aims to explore the different endovascular, endoscopic, radiological and surgical procedures available to diagnose and manage the most severe form of CF hepatobiliary involvement (CFHBI) known as advanced cystic fibrosis liver disease (aCFLD), seen in 10% of pwCF. These procedures and interventions include liver biopsy, hepatic venous pressure gradient measurement, gastrostomy tube placement to optimize nutrition, paracentesis, endoscopic variceal control of bleeding and portosystemic shunting before liver transplantation. By utilizing advanced diagnostic or surgical techniques, healthcare professionals of pwCF can more effectively manage patients with CFHBI and aCFLD and potentially improve patient outcomes.


Subject(s)
Cystic Fibrosis , Humans , Cystic Fibrosis/surgery , Cystic Fibrosis/complications , Cystic Fibrosis/diagnostic imaging , Liver Diseases/diagnostic imaging , Liver Diseases/surgery , Liver Transplantation , Endovascular Procedures/methods , Gastrostomy/methods , Portasystemic Shunt, Surgical/methods , Paracentesis/methods
14.
Adv Surg ; 58(1): 161-189, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39089775

ABSTRACT

This is a comprehensive review of carotid artery revascularization techniques: Carotid Endarterectomy (CEA), Transfemoral Carotid Artery Stenting (TFCAS), and Transcarotid Artery Revascularization (TCAR). CEA is the gold standard and is particularly effective in elderly and high-risk patients. TFCAS, introduced as a less invasive alternative, poses increased periprocedural stroke risks. TCAR, which combines minimally invasive benefits with CEA's neuroprotection principles, emerges as a safer option for high-risk patients, showing comparable results to CEA and better outcomes than TFCAS. The decision-making process for carotid revascularization is complex and influenced by the patient's medical comorbidities and anatomic factors.


Subject(s)
Endarterectomy, Carotid , Stents , Humans , Endarterectomy, Carotid/methods , Carotid Stenosis/surgery , Endovascular Procedures/methods , Treatment Outcome , Carotid Artery Diseases/surgery
15.
Adv Surg ; 58(1): 121-133, 2024 Sep.
Article in English | MEDLINE | ID: mdl-39089772

ABSTRACT

Chronic limb-threatening ischemia is defined as ischemic rest pain or tissue loss (eg, ulceration/gangrene) that has been present for greater than 2 weeks. Workup includes a careful history, physical examination focused on evaluation of pulses and wounds, lower extremity noninvasive vascular studies (eg, ankle-brachial indices, toe pressures), saphenous vein mapping, and imaging of the lower extremity arterial anatomy (eg, computed tomography, magnetic resonance, or subtraction angiography) if a revascularization intervention is planned.


Subject(s)
Endovascular Procedures , Ischemia , Humans , Endovascular Procedures/methods , Ischemia/surgery , Ischemia/etiology , Chronic Disease , Vascular Surgical Procedures/methods , Lower Extremity/blood supply , Chronic Limb-Threatening Ischemia/surgery , Limb Salvage/methods
16.
CNS Neurosci Ther ; 30(8): e14907, 2024 Aug.
Article in English | MEDLINE | ID: mdl-39118229

ABSTRACT

BACKGROUND: The ideal blood pressure (BP) target in patients who undergo endovascular thrombectomy (EVT) with successful reperfusion is uncertain. Observational studies show that elevated BP during this period is associated with a higher risk of intracranial hemorrhage (ICH) and worse clinical outcomes. Several randomized controlled trials (RCTs) have explored whether intensive BP lowering improves clinical outcomes in these patients. AIMS: This review aims to summarize the recent RCTs that compare intensive and conventional BP management strategies following EVT and discuss the innovative directions to improve. RESULT: The recently published RCTs failed to demonstrate the benefit of intensive BP control on the functional outcome and decreasing the risk of ICH. The complex mechanism in cerebral blood flow regulation and the inappropriate BP range chosen in RCTs may be the reasons behind the inconsistent results between observational studies and RCTs. Individualized BP management, reducing BP variability, and multi-stage BP management should be paid more attention in future exploration. CONCLUSION: Intensive BP target did not improve clinical outcomes after successful EVT as compared with a conventional BP target. Further research is required to identify the optimal BP management strategy after reperfusion.


Subject(s)
Blood Pressure , Endovascular Procedures , Randomized Controlled Trials as Topic , Thrombectomy , Humans , Randomized Controlled Trials as Topic/methods , Thrombectomy/methods , Endovascular Procedures/methods , Blood Pressure/physiology , Blood Pressure/drug effects
17.
Med Sci Monit ; 30: e944183, 2024 Aug 02.
Article in English | MEDLINE | ID: mdl-39091002

ABSTRACT

BACKGROUND Vertebral artery origin stenosis (VAOS) has recently gained increased attention, with endovascular treatments like stent implantation showing high success and low complication rates, although less is known about VAOS compared to carotid artery stenosis. This study evaluated the safety and effectiveness of transradial (TRA) and transfemoral (TFA) approaches for VAOS stent placement. MATERIAL AND METHODS We recruited a total of 102 patients undergoing vertebral artery stenting in our hospital between January 2020 and November 2022. Patients were randomly assigned to undergo either radial or femoral approach for stent implantation in the vertebral artery, and the radial approach group secondary divided into 2 groups by patients' consent: ipsilateral or contralateral radial approach. The success rates of VAOS stent implantation, operation time, and postoperative hospitalization time were compared between the 3 groups. In addition, we compared the outcomes of stroke within 30 days, transient ischemic attack (TIA) within 30 days, and other indicators. RESULTS Of the 102 patients, the final success rate of stent implantation was not significantly different between the 3 groups. The time from sheath insertion to stent insertion in the ipsilateral TRA group (median time: 19 min [interquartile range (IQR): 12-24.5 min]) was significantly shorter than in the transfemoral approach (TFA) group (median time: 29 min [IQR: 21-35.5 min]) (P<0.01; 95% confidence interval (95% CI): 10 min [6-14 min]). There were no statistically significant differences between the 3 groups in terms of cerebrovascular events within 1 month, and patient satisfaction and preference favored the radial approach. CONCLUSIONS The postoperative hospitalization time and operation time associated with the ipsilateral TRA were shorter, and patient acceptance and satisfaction were higher.


Subject(s)
Endovascular Procedures , Femoral Artery , Radial Artery , Stents , Vertebral Artery , Humans , Female , Male , Radial Artery/surgery , Femoral Artery/surgery , Prospective Studies , Middle Aged , Aged , Vertebral Artery/surgery , Endovascular Procedures/methods , Treatment Outcome , Vertebrobasilar Insufficiency/surgery
19.
BMC Surg ; 24(1): 221, 2024 Aug 05.
Article in English | MEDLINE | ID: mdl-39103860

ABSTRACT

BACKGROUND: Extracranial carotid artery aneurysm (ECAA) is a rare peripheral arterial disease. The main treatment strategies include conservative treatment, open surgery, endovascular treatment, and hybrid techniques, and there is no expert consensus or guidelines, with only a few case reports. METHOD: This article reviewed 10 cases diagnosed with "extracranial carotid artery aneurysm" and received invasive treatment from January 2013 to July 2023 in our medical center. RESULTS: There were 10 patients with ECAA admitted to our center, including seven cases of true aneurysms, two cases of pseudoaneurysms, and one case of dissecting aneurysm. There were 3 females and 7 males aged between 24-61 years. Based on the characteristics of ECAA, we designed the individualized procedure including open surgery, endovascular treatment, and hybrid treatment. Procedures were technically successful for all patients, and none of them had any adverse events during the follow-up period except for one patient who developed cerebral hemorrhage on the third postoperative day and recovered after cerebral puncture and drainage. CONCLUSION: The current invasive treatments for ECAA mainly include open surgery, endovascular treatment, and hybrid treatment, and they all appear to be safe and effective.


Subject(s)
Aneurysm , Carotid Artery Diseases , Endovascular Procedures , Humans , Adult , Male , Female , Middle Aged , Endovascular Procedures/methods , Carotid Artery Diseases/surgery , Carotid Artery Diseases/diagnosis , Carotid Artery Diseases/therapy , Aneurysm/surgery , Aneurysm/diagnosis , Young Adult , Treatment Outcome , Retrospective Studies
20.
J Robot Surg ; 18(1): 328, 2024 Aug 23.
Article in English | MEDLINE | ID: mdl-39174843

ABSTRACT

Although robot-assisted surgical procedures using the da Vinci robotic system (Intuitive Surgical, Sunnyvale, CA) have been performed in more than 13 million procedures worldwide over the last two decades, the vascular surgical community has yet to fully embrace this approach (Intuitive Surgical Investor Presentation Q3 (2023) https://investor.intuitivesurgical.com/static-files/dd0f7e46-db67-4f10-90d9-d826df00554e . Accessed February 22, 2024). In the meantime, endovascular procedures revolutionized vascular care, serving as a minimally invasive alternative to traditional open surgery. In the pursuit of a percutaneous approach, shorter postoperative hospital stay, and fewer perioperative complications, the long-term durability of open surgical vascular reconstruction has been compromised (in Lancet 365:2179-2186, 2005; Patel in Lancet 388:2366-2374, 2016; Wanhainen in Eur J Vasc Endovasc Surg 57:8-93, 2019). The underlying question is whether the robotic-assisted laparoscopic vascular surgical approaches could deliver the robustness and longevity of open vascular surgical reconstruction, but with a minimally invasive delivery system. In the meantime, other surgical specialties have embraced robot-assisted laparoscopic technology and mastered the essential vascular skillsets along with minimally invasive robotic surgery. For example, surgical procedures such as renal transplantation, lung transplantation, and portal vein reconstruction are routinely being performed with robotic assistance that includes major vascular anastomoses (Emerson in J Heart Lung Transplant 43:158-161, 2024; Fei in J Vasc Surg Cases Innov Tech 9, 2023; Tzvetanov in Transplantation 106:479-488, 2022; Slagter in Int J Surg 99, 2022). Handling and dissection of major vascular structures come with the inherent risk of vascular injury, perhaps the most feared complication during such robotic procedures, possibly requiring emergent vascular surgical consultation. In this review article, we describe the impact of a minimally invasive, robotic approach covering the following topics: a brief history of robotic surgery, components and benefits of the robotic system as compared to laparoscopy, current literature on "vascular" applications of the robotic system, evolving training pathways and future perspectives.


Subject(s)
Robotic Surgical Procedures , Vascular Surgical Procedures , Robotic Surgical Procedures/methods , Robotic Surgical Procedures/trends , Humans , Vascular Surgical Procedures/methods , Laparoscopy/methods , Endovascular Procedures/methods
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