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1.
Arch Gynecol Obstet ; 310(4): 1811-1821, 2024 10.
Article in English | MEDLINE | ID: mdl-39180564

ABSTRACT

PURPOSE: To evaluate the existing evidence regarding the comparison between 2 and 3D systems in Total Laparoscopic Hysterectomy (TLH) in terms of surgical outcomes. METHODS: A systematic review of electronic databases, including PubMed/MEDLINE and Web of Science, was conducted to identify relevant studies comparing 2D and 3D systems in TLH. The search employed a combination of Medical Subject Headings (MeSH) terms and keywords related to the topic. Studies meeting predefined criteria were included, while case reports and studies not directly comparing 2D and 3D systems were excluded. Two independent reviewers evaluated study eligibility and performed quality assessment. The quantitative synthesis was conducted using meta-analysis techniques. RESULTS: A statistically significant longer operation time in the 2D group compared to the 3D group (7 studies, mean difference [MD]: 13.67, 95% confidence interval [CI] 9.35-18.00, I2 = 16%). However, no statistically significant differences were found between the groups in terms of vaginal cuff closure time (2 studies, MD: 3.22, CI - 6.58-13.02, I2 = 96%), complication rate (7 studies, odds ratio [OD]: 1.74, CI 0.70-4.30, I2 = 0%), blood loss (3 studies, MD: 2.92, CI - 15.44-21.28, I2 = 0%), and Hb drop (3 studies, MD: 0.17, CI - 0.08-0.42, I2 = 1%). CONCLUSION: Our results revealed a significant difference favoring 3D systems in operation time, while clinical outcomes between the two systems were found to be comparable in TLH. However, further research, particularly prospective studies with larger cohorts and longer-term follow-up, along with economic analyses, is needed to provide clinicians and healthcare decision-makers with essential guidance for practice and resource allocation.


Subject(s)
Hysterectomy , Laparoscopy , Operative Time , Female , Humans , Blood Loss, Surgical/statistics & numerical data , Hysterectomy/adverse effects , Hysterectomy/instrumentation , Hysterectomy/methods , Hysterectomy/statistics & numerical data , Laparoscopy/adverse effects , Laparoscopy/instrumentation , Laparoscopy/methods , Laparoscopy/statistics & numerical data , Length of Stay/statistics & numerical data , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Treatment Outcome
2.
Asian J Endosc Surg ; 17(3): e13344, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38952290

ABSTRACT

INTRODUCTION: Hybrid total laparoscopic hysterectomy combines conventional laparoscopic surgery and robot-assisted devices: the camera and assistant forceps are operated by a robotic device, whereas the surgeon performs laparoscopic procedures, enabling surgery with a completely fixed field of view and significantly reducing errors in forceps grasping and needle misalignment. Here, we examined whether using two arms of the Hugo™ robot-assisted surgery system, one for the camera and one for the assistant, would improve surgical accuracy compared with conventional total laparoscopic hysterectomy. MATERIALS AND SURGICAL TECHNIQUE: The surgical system reduced surgeon errors in grasping the forceps during training and stabilized forceps operation. Compared with conventional laparoscopic surgery, the use of the surgical system did not result in different operative durations. The stable surgical procedure was considered a major advantage. DISCUSSION: This new technique involving new equipment can improve surgeon training and performance. In the future, we will develop new techniques to improve surgical performance.


Subject(s)
Hysterectomy , Laparoscopy , Robotic Surgical Procedures , Humans , Laparoscopy/methods , Robotic Surgical Procedures/instrumentation , Female , Hysterectomy/methods , Hysterectomy/instrumentation , Operative Time , Equipment Design , Middle Aged
3.
Updates Surg ; 76(5): 2051-2057, 2024 Sep.
Article in English | MEDLINE | ID: mdl-38787495

ABSTRACT

New robot models, such as hinotori™, da Vinci SP™, and Hugo™, have been introduced in Japan. This study examined the surgical outcomes of these models in patients from the initial stages of their introduction to the present day.We retrospectively reviewed 36 patients with endometrial cancer or benign gynecologic disease, who underwent robotic hysterectomy using da Vinci SP™, hinotori™, or Hugo™ between March 2023 and March 2024.Robotic hysterectomy was performed using hinotori™ in 10 patients, da Vinci SP™ in 16 patients, and Hugo™ in 10 patients. No significant differences were observed in the characteristics of the patients subjected to surgery using these models. The total operative time was 123.0 min (93-144 min) for hinotori™, 95.0 min (79-165 min) for da Vinci SP™, and 98.5 min (74-177 min) for Hugo™. The total operative time of hinotori™ was significantly longer than that of the other two models (p = 0.031). No differences were observed among the robot systems with respect to complications during or after surgery and the intensity of postoperative pain.Differences in the surgical time were noted depending on the model used. It has been proven that surgeons who are already proficient in performing robotic surgery with da Vinci Xi™ can safely perform surgeries with the new models.


Subject(s)
Hysterectomy , Operative Time , Robotic Surgical Procedures , Humans , Hysterectomy/methods , Hysterectomy/instrumentation , Female , Robotic Surgical Procedures/methods , Robotic Surgical Procedures/instrumentation , Retrospective Studies , Middle Aged , Treatment Outcome , Aged , Adult , Endometrial Neoplasms/surgery , Time Factors
5.
Arch Gynecol Obstet ; 309(4): 1249-1265, 2024 04.
Article in English | MEDLINE | ID: mdl-38127141

ABSTRACT

PURPOSE: One of the most challenging tasks in laparoscopic gynecological surgeries is suturing. Knotless barbed sutures are intended to enable faster suturing and hemostasis. We carried out a meta-analysis to compare the efficacy and safety of V-Loc™ barbed sutures (VBS) with conventional sutures (CS) in gynecological surgeries. METHODS: We systematically searched PubMed and EMBASE for studies published between 2010 and September 2021 comparing VBS to CS for OB/GYN procedures. All comparative studies were included. Primary analysis and subgroup analyses for the different surgery and suturing types were performed. Primary outcomes were operation time and suture time; secondary outcomes included post-operative complications, surgical site infections, estimated blood loss, length of stay, granulation tissue formation, and surgical difficulty. Results were calculated as weighted mean difference (WMD) or risk ratio (RR) and 95% confidence intervals (CI) with a random effects model, and a sensitivity analysis for study quality, study size, and outlier results was performed. PROSPERO registration: CRD42022363187. RESULTS: In total, 25 studies involving 4452 women undergoing hysterectomy, myomectomy, or excision of endometrioma. VBS were associated with a reduction in operation time (WMD - 17.08 min; 95% CI - 21.57, - 12.59), suture time (WMD - 5.39 min; 95% CI - 7.06, - 3.71), surgical site infection (RR 0.26; 95% CI 0.09, 0.78), estimated blood loss (WMD - 44.91 ml; 95% CI - 66.01, - 23.81), granulation tissue formation (RR 0.48; 95% CI 0.25, 0.89), and surgical difficulty (WMD - 1.98 VAS score; 95% CI - 2.83, - 1.13). No difference between VBS and CS was found regarding total postoperative complications or length of stay. Many of the outcomes showed high heterogeneity, likely due to the inclusion of different surgery types and comparators. Most results were shown to be robust in the sensitivity analysis except for the reduction in granulation tissue formation. CONCLUSION: This meta-analysis indicates that V-Loc™ barbed sutures are safe and effective in gynecological surgeries as they reduce operation time, suture time, blood loss, infections, and surgical difficulty without increasing post-operative complications or length of stay compared to conventional sutures.


Subject(s)
Gynecologic Surgical Procedures , Surgical Wound Infection , Suture Techniques , Female , Humans , Blood Loss, Surgical , Gynecologic Surgical Procedures/methods , Gynecologic Surgical Procedures/instrumentation , Gynecologic Surgical Procedures/adverse effects , Hysterectomy/methods , Hysterectomy/adverse effects , Hysterectomy/instrumentation , Laparoscopy/adverse effects , Laparoscopy/methods , Length of Stay , Operative Time , Postoperative Complications/etiology , Postoperative Complications/epidemiology , Surgical Wound Infection/prevention & control , Surgical Wound Infection/etiology , Suture Techniques/instrumentation , Suture Techniques/adverse effects , Sutures , Uterine Myomectomy/methods , Uterine Myomectomy/adverse effects , Uterine Myomectomy/instrumentation
6.
Am J Perinatol ; 39(3): 265-271, 2022 02.
Article in English | MEDLINE | ID: mdl-32819018

ABSTRACT

OBJECTIVE: This study aimed to describe a novel surgical technique for the management of antenatally suspected placenta accreta spectrum (PAS). STUDY DESIGN: This is a retrospective, case series of patients with suspected PAS undergoing peripartum hysterectomy with a reloadable articulating stapler at a tertiary care center. RESULTS: Eighteen patients with antenatally suspected PAS were identified and underwent peripartum hysterectomy with the aid of a reloadable stapler. Mean gestational age at delivery was 344/7 ± 11/7 weeks. Mean total operative time (skin-to-skin) was 117.3 ± 39.3 minutes, and 79.8 ± 19.8 minutes for the hysterectomy. Mean blood loss for the entire case was 1,809 ± 868 mL. Mean blood loss for the hysterectomy was 431 ± 421 mL. Mean units of intraoperative red blood cells transfused was 3 ± 1 units. Mean units of postoperative red blood cells transfused was 1 ± 0.5 units. Five cases were complicated by urological injury (two intentional cystotomies). Four patients were admitted to the intensive care unit (ICU) for a mean of ≤24 hours. Mean postoperative LOS was 4.11 ± 1.45 days. Three patients had final pathology that did not demonstrate PAS while four were consistent with accreta, six increta, and five percreta. CONCLUSION: Use of a reloadable articulating stapler device as part of the surgical management of antenatally suspected PAS results in a shorter operative time (117 ± 39 minutes vs. 140-254 minutes previously reported), lower average blood loss (1,809 ± 868 mL vs. 2,500-5,000 mL previously reported) and shorter LOS (4.11 ± 1.45 days vs. 9.8 ± 13.5 days previously reported) compared with traditional cesarean hysterectomy. The reloadable stapling device offers an advantage of more rapidly achieving hemostasis in the surgical management of PAS. KEY POINTS: · PAS is associated with severe maternal morbidity.. · Decreased operative time and blood loss have many clinical benefits.. · Reloadable stapler use for PAS decreases operative time.. · Reloadable stapler use for PAS decreases operative blood loss..


Subject(s)
Cesarean Section/instrumentation , Hemostasis, Surgical/instrumentation , Hysterectomy/instrumentation , Placenta Accreta/surgery , Surgical Staplers , Adult , Blood Loss, Surgical/prevention & control , Cesarean Section/methods , Equipment Design , Female , Hemostasis, Surgical/methods , Humans , Operative Time , Peripartum Period , Pregnancy , Retrospective Studies
7.
J Gynecol Obstet Hum Reprod ; 50(10): 102211, 2021 Dec.
Article in English | MEDLINE | ID: mdl-34481135

ABSTRACT

Gynecologic oncologists had originally preferred minimally invasive surgery (MIS) over laparotomic surgery for patients with early-stage cervical cancer until the Laparoscopic Approach to Cervical Cancer (LACC) trial reported a worse prognosis and more loco-regional recurrence in patients treated with MIS. Although some controversy remains, experts suggested that tumor cell spillage and aggravation may have been caused by intra-corporeal colpotomy, usage of uterine elevators, maintenance of Trendelenburg position, and tumor irritation by capnoperitoneum during surgery. Thus, we introduce a surgical procedure with some steps added to the conventional MIS radical hysterectomy for preventing tumor spillage during the surgery, which is currently being evaluated in terms of safety and efficacy through a prospective, multicenter, single-arm, phase II study, entitled "Safety of laparoscopic or robotic radical surgery using endoscopic stapler for inhibiting tumor spillage of cervical neoplasms (SOLUTION trial: NCT04370496)".


Subject(s)
Hysterectomy/methods , Uterine Cervical Neoplasms/surgery , Adult , Endoscopy/instrumentation , Endoscopy/methods , Female , Humans , Hysterectomy/instrumentation , Hysterectomy/statistics & numerical data , Minimally Invasive Surgical Procedures/instrumentation , Minimally Invasive Surgical Procedures/methods , Minimally Invasive Surgical Procedures/statistics & numerical data , Neoplasms , Prospective Studies , Surgical Staplers , Uterine Cervical Neoplasms/complications , Uterine Hemorrhage/diagnosis , Uterine Hemorrhage/surgery
8.
JSLS ; 25(1)2021.
Article in English | MEDLINE | ID: mdl-33880002

ABSTRACT

BACKGROUND AND OBJECTIVES: Laparoscopic hysterectomy provides patients and surgeons with benefits of less pain, quicker recovery, and better scar cosmesis. Previously, robotic surgical hysterectomy was reserved for patients with complicated disease issues. The objective of this case series was evaluating a new robotic surgical platform, Senhance Surgical System, as a surgical tool in common gynecological procedures. METHODS: The clinic routinely collects surgical and outcome data for all patients and procedures. Data on robotic surgery in hysterectomy, salpingectomy, endometriosis excision, and lysis of adhesions was evaluated. RESULTS: Fifteen consecutive patients that underwent gynecological surgery using the Senhance System were assessed. Average age was 47.27 years (31 - 63 years). Ten procedures were robotic total laparoscopic hysterectomy and 14 of 15 procedures had at least one salpingectomy. Average blood loss was 52.7 mL (10 - 100 mL). Pain scores at discharge averaged 1.42 and 2.73 at two weeks post-surgery. Minimal pain medication was used. Patient satisfaction with the surgery was 98% and satisfaction with scarring was 100%. Return to normal activities and to work averaged 7.93 and 11.1 days respectively. The haptic feedback and the platform visualization of the procedure was useful. The system provided more surgeon control over both camera and tools compared to previously used robotic systems and traditional laparoscopic surgery. CONCLUSION: This initial experience with Senhance Surgical System provided a stable, precise surgical technique with enhanced visualization within the confined space of the abdomen during gynecological surgery. The initial results suggest high patient satisfaction with gynecological surgery and resulting scars. Further study is needed to validate the findings.


Subject(s)
Endometriosis/surgery , Genital Diseases, Female/surgery , Hysterectomy/instrumentation , Laparoscopy/instrumentation , Robotic Surgical Procedures/instrumentation , Salpingectomy/instrumentation , Adult , Cicatrix/etiology , Cicatrix/prevention & control , Female , Genital Diseases, Female/complications , Genital Diseases, Female/diagnosis , Humans , Hysterectomy/adverse effects , Laparoscopy/adverse effects , Middle Aged , Patient Satisfaction , Retrospective Studies , Robotic Surgical Procedures/adverse effects , Salpingectomy/adverse effects
9.
J Robot Surg ; 15(1): 31-35, 2021 Feb.
Article in English | MEDLINE | ID: mdl-32266667

ABSTRACT

Robotic-assisted surgery is criticized for its high cost. As surgeons get more experienced in robotic surgery, modifications to existing techniques are tried to reduce surgical costs. Vaginal cuff closure using prograsp forceps in lieu of needle holder can be safe and cost-effective in patients undergoing robotic-assisted hysterectomy. The objective of this study is to compare the safety, efficacy, and cost effectiveness of using prograsp forceps in lieu of needle holder for suturing the vaginal cuff after robotic-assisted hysterectomy. This was a single-institution retrospective review of patients who underwent robotic-assisted hysterectomy for benign and malignant conditions from October 2015 to August 2018. Patients were stratified based on whether prograsp forceps or needle holder was used for suturing vaginal cuff. Data obtained included demographic, surgical data, and postoperative outcomes. Mann-Whitney U test and Chi-square test were used to compare qualitative and quantitative data, respectively. 367 patients underwent robotic-assisted hysterectomies during this period. 75 patients belonged to the needle holder cohort; 292 patients had vaginal cuff closure using prograsp forceps. Vault closure time was comparable between the groups (6.4 vs. 6.6 p = 0.33). There were no significant differences in the postoperative vault-related complications between groups. There was no instrument damage in either group. Using prograsp saved 220 USD in instrument-related charges. This study shows that using prograsp in lieu of needle holder for suturing is safe, there is no increase in operative time or complications, and there is a cost advantage.


Subject(s)
Cost Savings/economics , Cost-Benefit Analysis , Hysterectomy/economics , Hysterectomy/instrumentation , Needles/economics , Robotic Surgical Procedures/economics , Robotic Surgical Procedures/instrumentation , Surgical Instruments/economics , Suture Techniques/economics , Suture Techniques/instrumentation , Vagina/surgery , Wound Closure Techniques/economics , Wound Closure Techniques/instrumentation , Aged , Female , Humans , Hysterectomy/methods , Middle Aged , Retrospective Studies , Robotic Surgical Procedures/methods , Safety , Treatment Outcome
10.
Am J Obstet Gynecol ; 224(1): 65.e1-65.e11, 2021 01.
Article in English | MEDLINE | ID: mdl-32693096

ABSTRACT

BACKGROUND: There are limited data available to indicate whether oncological outcomes might be influenced by the uterine manipulator, which is used at the time of hysterectomy for minimally invasive surgery in patients with endometrial cancer. The current evidence derives from retrospective studies with limited sample sizes. Without substantial evidence to support its use, surgeons are required to make decisions about its use based only on their personal choice and surgical experience. OBJECTIVE: To evaluate the use of the uterine manipulator on oncological outcomes after minimally invasive surgery, for apparent early-stage endometrial cancer. STUDY DESIGN: We performed a retrospective multicentric study to assess the oncological safety of uterine manipulator use in patients with apparent early-stage endometrial cancer, treated with minimally invasive surgery. The type of manipulator, surgical staging, histology, lymphovascular space invasion, International Federation of Gynecology and Obstetrics stage, adjuvant treatment, recurrence, and pattern of recurrence were evaluated. The primary objective was to determine the relapse rate. The secondary objective was to determine recurrence-free survival, overall survival, and the pattern of recurrence. RESULTS: A total of 2661 women from 15 centers were included; 1756 patients underwent hysterectomy with a uterine manipulator and 905 without it. Both groups were balanced with respect to histology, tumor grade, myometrial invasion, International Federation of Gynecology and Obstetrics stage, and adjuvant therapy. The rate of recurrence was 11.69% in the uterine manipulator group and 7.4% in the no-manipulator group (P<.001). The use of the uterine manipulator was associated with a higher risk of recurrence (hazard ratio, 2.31; 95% confidence interval, 1.27-4.20; P=.006). The use of uterine manipulator in uterus-confined endometrial cancer (International Federation of Gynecology and Obstetrics [FIGO] I-II) was associated with lower disease-free survival (hazard ratio, 1.74; 95% confidence interval, 0.57-0.97; P=.027) and higher risk of death (hazard ratio, 1.74; 95% confidence interval, 1.07-2.83; P=.026). No differences were found regarding the pattern of recurrence between both groups (chi-square statistic, 1.74; P=.63). CONCLUSION: In this study, the use of a uterine manipulator was associated with a worse oncological outcome in patients with uterus-confined endometrial cancer (International Federation of Gynecology and Obstetrics I-II) who underwent minimally invasive surgery. Prospective trials are essential to confirm these results.


Subject(s)
Endometrial Neoplasms/surgery , Hysterectomy/instrumentation , Neoplasm Recurrence, Local/surgery , Aged , Carcinoma, Endometrioid/mortality , Carcinoma, Endometrioid/surgery , Disease-Free Survival , Endometrial Neoplasms/mortality , Female , Humans , Middle Aged , Minimally Invasive Surgical Procedures/instrumentation , Neoplasm Recurrence, Local/mortality , Retrospective Studies , Spain , Treatment Outcome
11.
J Robot Surg ; 15(3): 451-456, 2021 Jun.
Article in English | MEDLINE | ID: mdl-32710253

ABSTRACT

The main objective of this study was to assess in a series of 30 patients, the feasibility, oncological safety and efficacy of radical hysterectomy by a new robotic system. Prospective study design. Galaxy Care Laparoscopy Institute and Multispeciality Hospital. We performed Robotic Radical Hysterectomy in patients from August 2019 through February 2020. All the surgeries were performed by a single surgeon (Puntambekar S). Since August 2019, 30 patients with early cervical cancer/endometrial cancer were selected for radical hysterectomy. All patients were in good general condition with controlled medical comorbidities. The mean operative time was 104 min, with mean total lymph node yield of 24.7. The average blood loss was 60 ml and the hospital stay was 2.1 days, and majority of the patients were catheter free by 1 week. Two patients developed uretero-vaginal fistula on the 8th day of surgery. One was managed with Double J stenting and in the other we did laparoscopic ureteroneocystostomy. Our study has demonstrated the feasibility, safety and efficacy of RRH by the Versius robotic systems.


Subject(s)
Endometrial Neoplasms/surgery , Hysterectomy/instrumentation , Robotic Surgical Procedures/instrumentation , Uterine Cervical Neoplasms/surgery , Blood Loss, Surgical/statistics & numerical data , Feasibility Studies , Female , Humans , Hysterectomy/adverse effects , Hysterectomy/methods , Middle Aged , Operative Time , Postoperative Complications/etiology , Robotic Surgical Procedures/adverse effects , Robotic Surgical Procedures/methods , Safety , Treatment Outcome , Urinary Fistula/etiology , Vaginal Fistula/etiology
12.
J Robot Surg ; 15(2): 241-249, 2021 Apr.
Article in English | MEDLINE | ID: mdl-32506299

ABSTRACT

Although robotic single-site (RSS) surgery employing cross setup of semirigid instruments allows effective triangulation of instruments, it has some limitations in performing RSS transabdominal and transvaginal surgeries. We introduced the robotic glove port technique (RGPT) using parallel setup of endowristed rigid instruments in performing RSS transabdominal surgery and transvaginal surgery in July of 2017. Thirty-five patients underwent RSS surgery with RGPT. Twenty-one patients had RSS transabdominal reconstructive or fertility-preserving surgeries such as myomectomy (12 patients), adenomyomectomy (3 patients), and ovarian endometriosis cystectomy (6 patients). Fourteen patients underwent robotic transvaginal surgery for natural orifice transluminal endoscopic surgery (NOTES) hysterectomy. All procedures were successfully performed, and no postoperative complications were observed. In all patients, the median total operative time, console time, and docking time were 160 min (range 106-240), 120 min (range 65-180), and 10 min (range 4-25), respectively. There was no conversion to another type of surgery, such as conventional laparoscopy, laparotomy, or traditional multiport robotic surgery. The findings showed that RSS surgery via the RGPT is safe and feasible, using the parallel setup of endowristed rigid instruments is easily performed on transvaginal routes and transabdominal routes. Therefore, this procedure may be an important complement to gynecologic surgeons' armamentarium in the field of robotic reconstructive or fertility-preserving surgeries such as myomectomy, adenomyomectomy, ovarian cystectomy, and transvaginal surgery for NOTES hysterectomy. Nevertheless, further prospective controlled studies are needed to determine its full clinical application.


Subject(s)
Gynecologic Surgical Procedures/instrumentation , Natural Orifice Endoscopic Surgery/instrumentation , Plastic Surgery Procedures/instrumentation , Robotic Surgical Procedures/instrumentation , Abdomen/surgery , Cystectomy/instrumentation , Cystectomy/methods , Female , Gynecologic Surgical Procedures/methods , Humans , Hysterectomy/instrumentation , Hysterectomy/methods , Natural Orifice Endoscopic Surgery/methods , Plastic Surgery Procedures/methods , Robotic Surgical Procedures/methods , Uterine Myomectomy/instrumentation , Uterine Myomectomy/methods , Vagina/surgery
13.
Int J Gynecol Cancer ; 30(12): 1864-1870, 2020 12.
Article in English | MEDLINE | ID: mdl-33037109

ABSTRACT

OBJECTIVES: Minimally invasive radical hysterectomy is associated with decreased survival in patients with early cervical cancer. The objective of this study was to determine whether the use of an intra-uterine manipulator at the time of laparoscopic or robotic radical hysterectomy is associated with inferior oncologic outcomes. METHODS: A retrospective cohort study was carried out of all patients with cervical cancer (squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma) International Federation of Gynecology and Obstetrics 2009 stages IA1 (with positive lymphovascular space invasion) to IIA who underwent minimally invasive radical hysterectomy at two academic centers between January 2007 and December 2017. Treatment, tumor characteristics, and survival data were retrieved from hospital records. RESULTS: A total of 224 patients were identified at the two centers; 115 had surgery with the use of an intra-uterine manipulator while 109 did not; 53 were robotic and 171 were laparoscopic. Median age was 44 years (range 38-54) and median body mass index was 25.8 kg/m2 (range 16.6-51.5). Patients in whom an intra-uterine manipulator was not used at the time of minimally invasive radical hysterectomy were more likely to have residual disease at hysterectomy (p<0.001), positive lymphovascular space invasion (p=0.02), positive margins (p=0.008), and positive lymph node metastasis (p=0.003). Recurrence-free survival at 5 years was 80% in the no intra-uterine manipulator group and 94% in the intra-uterine manipulator group. After controlling for the presence of residual cancer at hysterectomy, tumor size and high-risk pathologic criteria (positive margins, parametria or lymph nodes), the use of an intra-uterine manipulator was no longer significantly associated with worse recurrence-free survival (HR 0.4, 95% CI 0.2 to 1.0, p=0.05). The only factor which was consistently associated with recurrence-free survival was tumor size (HR 2.1, 95% CI 1.5 to 3.0, for every 10 mm increase, p<0.001). CONCLUSION: After controlling for adverse pathological factors, the use of an intra-uterine manipulator in patients with early cervical cancer who underwent minimally invasive radical hysterectomy was not an independent factor associated with rate of recurrence.


Subject(s)
Hysterectomy/instrumentation , Minimally Invasive Surgical Procedures/instrumentation , Robotic Surgical Procedures/instrumentation , Uterine Cervical Neoplasms/surgery , Adult , Canada/epidemiology , Cohort Studies , Disease-Free Survival , Female , Humans , Hysterectomy/statistics & numerical data , Kaplan-Meier Estimate , Middle Aged , Minimally Invasive Surgical Procedures/statistics & numerical data , Neoplasm Recurrence, Local/pathology , Retrospective Studies , Robotic Surgical Procedures/statistics & numerical data , Uterine Cervical Neoplasms/mortality , Uterine Cervical Neoplasms/pathology
14.
Eur J Surg Oncol ; 46(7): 1225-1232, 2020 07.
Article in English | MEDLINE | ID: mdl-32360066

ABSTRACT

BACKGROUND: Minimally invasive surgery has achieved great success in the surgical treatment of many kinds of cancer. This study aimed to systematically review the available evidence evaluating the effects of the use of uterine manipulators in minimally hysterectomies for endometrial cancer patients. METHODS: We searched the CENTRAL, MEDLINE, PubMed, EMBASE and ClinicalTrials.gov databases to Sep. 12, 2019 to identify relevant prospective or retrospective studies, using the intersection of "endometrial neoplasms", "endometrial carcinoma", "endometrial cancer"; "uterine manipulator", and "intrauterine manipulator". The initial search identified 251 items in total. The main outcomes of interest were the presence of LVSI (lymphovascular space invasion), the incidence of positive peritoneal cytology, and the presence of recurrence during follow-up. RESULTS: After screening for eligibility, 11 studies were included in the meta-analysis finally. The timing of uterine manipulators insertion during MIS for endometrial cancer was not associated with an increased risk of positive peritoneal cytology (RR: 1.21, 95% CI, 0.68 to 2.16). Moreover, there was no significant difference for the rate of positive peritoneal cytology (RR: 1.53, 95% CI, 0.85 to 2.77), LVSI (RR: 1.18, 95% CI, 0.66 to 2.11) or the rate of recurrence (RR: 1.25, 95% CI, 0.89 to 1.74) regarding the use of uterine manipulators for laparoscopic surgery in the treatment of endometrial cancer patients. CONCLUSION: We found that the use of uterine manipulators is not associated with an increased incidence of positive peritoneal cytology, LVSI, or recurrence among patients with endometrial cancer. SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42020147111.


Subject(s)
Endometrial Neoplasms/pathology , Endometrial Neoplasms/surgery , Hysterectomy/instrumentation , Neoplasm Recurrence, Local , Neoplasm Seeding , Peritoneum/pathology , Blood Vessels/pathology , Female , Humans , Hysterectomy/methods , Lymphatic Vessels/pathology , Minimally Invasive Surgical Procedures/instrumentation , Neoplasm Invasiveness , Neoplasm Recurrence, Local/pathology
15.
JSLS ; 24(1)2020.
Article in English | MEDLINE | ID: mdl-32161433

ABSTRACT

BACKGROUND: One of the challenges of robotic gynecologic surgery is the appropriate traction of the organs and other structures surrounding the surgical field. METHODS: We developed a novel traction device, VESOPASTA, that can be used for organ traction during robotic gynecologic surgery. This study describes the utility and the safety of the use of VESOPASTA for ureteral traction during robotic-assisted laparoscopic radical hysterectomy in five cervical cancer patients. RESULTS: Ureteral suspension was successfully and safely performed using VESOPASTA during robotic-assisted laparoscopic radical hysterectomy in cervical cancer patients without causing any complications. The average time required for this procedure was less than 5 min. CONCLUSIONS: We have developed a novel device, VESOPASTA, which can be used for organ traction during robotic surgery. This new device allows easy ureteral traction, facilitate the identification of ureter and prevent ureteral injuries during robotic-assisted laparoscopic radical hysterectomy.


Subject(s)
Carcinoma, Squamous Cell/surgery , Hysterectomy/instrumentation , Laparoscopy/instrumentation , Silicon , Traction/instrumentation , Uterine Cervical Neoplasms/surgery , Adult , Cohort Studies , Female , Humans , Hysterectomy/methods , Laparoscopy/methods , Middle Aged
16.
JSLS ; 24(1)2020.
Article in English | MEDLINE | ID: mdl-32161436

ABSTRACT

BACKGROUND AND OBJECTIVES: Gasless laparoscopy is an alternative method to reduce the number of carbon dioxide (CO2)-insufflated, pneumoperitoneum-related problems including shoulder pain, postoperative nausea/vomiting, and decreased cardiopulmonary function. In this study, we investigated the feasibility of gasless total laparoscopic hysterectomy (TLH) with a newly developed abdominal-wall retraction system. METHODS: Abdominal-wall retraction for gasless laparoscopy was performed using the newly developed J-shape retractor and the Thompson surgical retractor. Surgical outcomes between gasless TLH and conventional CO2-based TLH were compared for each of 40 patients for the period from January 2017 to October 2019. RESULTS: Between gasless TLH and conventional CO2-based TLH, no significant differences were observed for age, body mass index, parity, or surgical indications. The mean retraction setup time from skin incision was 7.4 min (range: 4-12 min) with gasless TLH. The mean total operation times were 87.9 min (range: 65-170) with gasless TLH and 90 min (range: 45-180) with conventional TLH, which showed no significant difference. Estimated blood loss and uterus weight also showed no significant intergroup difference. No major complications related to the ureter, bladder, or bowel were encountered. CONCLUSION: Our new abdominal-wall retraction system for gasless TLH allowed for easy setup and a proper operation field in the performance of laparoscopic hysterectomy.


Subject(s)
Abdominal Wall/surgery , Hysterectomy/instrumentation , Laparoscopy/instrumentation , Uterine Diseases/surgery , Adult , Aged , Feasibility Studies , Female , Humans , Hysterectomy/methods , Laparoscopy/methods , Middle Aged , Operative Time , Retrospective Studies , Uterine Diseases/pathology , Young Adult
17.
J Minim Invasive Gynecol ; 27(3): 583-592, 2020.
Article in English | MEDLINE | ID: mdl-31954185

ABSTRACT

Power morcellation in laparoscopic surgery enables specialists to carry out minimally invasive procedures such as hysterectomies and myomectomies by cutting specimens into smaller pieces using a rotating blade and removing pieces through a laparoscope. Unexpected uterine sarcoma treated by surgery involving tumor disruption could be associated with poor prognosis. The current study aims to shed light on power morcellation from a medicolegal perspective: the procedure has resulted in adverse outcomes and litigation, and compensation for plaintiffs, as published in various journals cited in PubMed and MEDLINE, Cochrane Library, EMBASE, and GyneWeb. Considering the claims after the US Food and Drug Administration warnings on morcellation, the current study broadens the scope of research by including search engines, legal databases, and court filings (DeJure, Lexis Nexis, Justia, superior court of New Jersey, and US district court of Minnesota) between 1995 and 2019. Legal records show that courts determine professional responsibility regarding complications, making it essential to document adherence to safety protocols and specific guidelines, when available. Sound medical practices and clearly stated institute best practices result in better patient outcomes and are important when unfavorable clinical outcomes occur; adverse legal decisions can be avoided if there are grounds to prove professional conformity with specific guidelines and the unpredictability of an event.


Subject(s)
Gynecology/legislation & jurisprudence , Liability, Legal , Morcellation/legislation & jurisprudence , Uterine Myomectomy/legislation & jurisprudence , Uterine Neoplasms/surgery , Female , Gynecology/statistics & numerical data , History, 20th Century , History, 21st Century , Humans , Hysterectomy/instrumentation , Hysterectomy/legislation & jurisprudence , Hysterectomy/methods , Jurisprudence/history , Laparoscopy/instrumentation , Laparoscopy/legislation & jurisprudence , Laparoscopy/methods , Liability, Legal/history , Morcellation/instrumentation , Morcellation/methods , Physician-Patient Relations , Practice Patterns, Physicians'/legislation & jurisprudence , Practice Patterns, Physicians'/standards , Practice Patterns, Physicians'/statistics & numerical data , Prognosis , Sarcoma/diagnosis , Sarcoma/epidemiology , Sarcoma/surgery , Treatment Outcome , United States/epidemiology , United States Food and Drug Administration , Uterine Myomectomy/instrumentation , Uterine Myomectomy/methods , Uterine Neoplasms/diagnosis , Uterine Neoplasms/epidemiology
18.
J Minim Invasive Gynecol ; 27(7): 1471-1472, 2020.
Article in English | MEDLINE | ID: mdl-31926301

ABSTRACT

OBJECTIVE: Minimally invasive surgery (MIS) for radical hysterectomy (RH) has been reported with inferior oncologic outcomes in the New England Journal of Medicine [1,2]. Some studies have suggested that the no-touch technique may be a useful procedure to prevent tumor spillage and improve survival. Therefore, we performed RH targeting early-stage cervical cancer using the laparoendoscopic single-site (LESS) approach with an enclosed colpotomy and without a uterine manipulator [3]. DESIGN: Video demonstration of the technique. SETTING: A hospital. INTERVENTIONS: A 48-year-old postmenopausal woman received a diagnosis of stage IB1 (International Federation of Gynecology and Obstetrics, 2018) cervical cancer [4]. After being fully informed of the benefits and risks of different surgical approaches (laparotomy and MIS), she consented to the MIS. The type C RH through the LESS approach was performed successfully. The final pathologic findings confirmed stage IB1 cervical carcinoma. The patient recovered quickly, albeit with slight pain, and the incision scar was hidden perfectly for cosmetic purposes. CONCLUSION: This video demonstrates that LESS-RH with vaginal closure and without a manipulator is feasible and safe. Suspension skills played a significant role in LESS-RH. In addition, this surgical procedure involved 4 specific techniques to prevent tumor spillage: creation of a vaginal cuff, avoidance of a uterine manipulator, standard type C radical hysterectomy, and bagging of the specimen. These adaptations were meant to minimize tumor manipulation and disruption for reducing the increased risk of recurrence. However, further verifications are still required.


Subject(s)
Carcinoma, Squamous Cell/surgery , Hysterectomy/methods , Laparoscopy/methods , Uterine Cervical Neoplasms/surgery , Vagina/surgery , Carcinoma, Squamous Cell/pathology , Colpotomy/methods , Female , Humans , Hysterectomy/instrumentation , Laparoscopy/instrumentation , Middle Aged , Minimally Invasive Surgical Procedures/methods , Neoplasm Staging , Uterine Cervical Neoplasms/pathology , Wound Closure Techniques
19.
Femina ; 48(1): 43-48, jan. 31, 2020. ilus
Article in Portuguese | LILACS | ID: biblio-1052442

ABSTRACT

No ano de 2018, aproximadamente 549.000 cirurgias robóticas em ginecologia foram realizadas no mundo, ocupando o segundo lugar em volume de procedimentos. Estudos sugerem superioridade ou equivalência dessa tecnologia em relação à cirurgia laparoscópica, porém o custo, a disponibilidade e o treinamento limitam sua adoção. Nesta revisão narrativa, os principais benefícios e limitações dos procedimentos ginecológicos robóticos foram analisados. O uso de robôs na histerectomia para o tratamento de lesões benignas apresentou menor incidência de lesões iatrogênicas e de sangramentos em relação à laparoscopia convencional. Na miomectomia robótica, além de menor taxa de complicações, maior volume de miomas retirados foi observado. A cirurgia robótica tem sido bem-sucedida para cirurgias de estadiamento no câncer de endométrio em estágios precoces (I e II), devido à menor taxa de complicações em relação à cirurgia aberta e aos resultados satisfatórios obtidos em mulheres obesas. A histerectomia robótica realizada no tratamento de câncer de colo do útero apresentou menor perda sanguínea em parte dos estudos, porém um ensaio clínico recente demonstrou maior mortalidade no grupo dos procedimentos minimamente invasivos. Espera-se que, com a redução dos custos e a ampliação dos treinamentos, a cirurgia robótica seja uma ferramenta complementar às modalidades já existentes.(AU)


In 2018, 549,000 robotic gynecology surgeries were done in the world, ranking second in volume of procedures. Studies suggest the superiority or equivalence of this technology over laparoscopic surgery, but its cost, availability, and training limit its adoption. In this narrative review, the benefits and limitations of robotic gynecological procedures were investigated. Using robots in hysterectomy for the management of benign lesions showed a lower incidence of iatrogenic lesions and bleeding compared to conventional laparoscopy. In robotic myomectomy, besides a lower complication rate, a larger volume of removed fibroids was noted. Robotic surgery has been successful in the early stages (I and II) endometrial cancer staging surgeries, because of the lower complication rate compared to open surgery and the satisfactory results achieved in obese women. Robotic hysterectomy performed in the treatment of cervical cancer showed less blood loss in part of the studies, but a recent clinical trial showed higher mortality in the minimally invasive procedures group. It is desired that with the reduction of costs and the spread of training robotic surgery will be a complementary tool to existing modalities.(AU)


Subject(s)
Humans , Female , Gynecologic Surgical Procedures/methods , Robotic Surgical Procedures , Postoperative Complications , Randomized Controlled Trials as Topic , Databases, Bibliographic , Treatment Outcome , Laparoscopy/methods , Uterine Myomectomy/instrumentation , Genital Neoplasms, Female/surgery , Hysterectomy/instrumentation , Intraoperative Complications , Leiomyoma/surgery
20.
J Minim Invasive Gynecol ; 27(4): 809-810, 2020.
Article in English | MEDLINE | ID: mdl-31518713

ABSTRACT

STUDY OBJECTIVE: To perform a radical hysterectomy for early-stage cervical cancer through laparoendoscopic single-site (LESS) approach and demonstrate if the effective suspension could achieve different exposed purposes and space extension. DESIGN: Presentation of the surgery through this technical video. SETTING: Hospital. INTERVENTIONS: A 52-year-old menopausal woman who presented with postcoital bleeding for 3 months was diagnosed with poorly differentiated (G3) cervical squamous cell carcinoma with International Federation of Gynecology and Obstetrics stage IB1. The patient was carefully consulted about the oncologic risks of the different surgical approaches; thereafter, the LESS approach was decided with informed consent. The LESS procedures for staging surgery were completed. The estimated blood loss was 60 mL, and operation time was 250 minutes. Results of the pathology report showed G3 squamous cell carcinoma and no pelvic lymph nodes metastases. The Foley catheter was removed on the 21st day, and the bladder function recovered completely after removal. She was followed up for a year without any evidence of recurrence or complications. CONCLUSION: Because of technical difficulties with a limited number of hands, complex surgeries, such as radical hysterectomy, have rarely been performed using the LESS approach [1]. The dissection of vesicocervical and parametrial space is critical to radical hysterectomy, and inadequate exposure to these spaces during the procedure presents major difficulties [2]. In the video, surgery for cervical cancer was performed successfully and met the International Federation of Gynecology and Obstetrics' standards for type C radical hysterectomy. Our video demonstrated that the varied and flexible suspension played a significant role in providing clear vision and sufficient exposure; furthermore, it was feasible, effective, and safe in the LESS approach [3,4].


Subject(s)
Carcinoma, Squamous Cell/surgery , Hysterectomy , Laparoscopy , Uterine Cervical Neoplasms/surgery , Carcinoma, Squamous Cell/pathology , Female , Humans , Hysterectomy/instrumentation , Hysterectomy/methods , Hysteroscopy/instrumentation , Hysteroscopy/methods , Laparoscopy/instrumentation , Laparoscopy/methods , Lymph Node Excision/instrumentation , Lymph Node Excision/methods , Lymph Nodes/pathology , Middle Aged , Neoplasm Recurrence, Local/surgery , Neoplasm Staging , Operative Time , Pelvis/pathology , Surgical Instruments , Treatment Outcome , Uterine Cervical Neoplasms/pathology
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