ABSTRACT
Cutaneous malakoplakia is a rare infection-related granulomatous disease frequently associated with immunocompromised states. Foamy macrophages containing basophilic granules, called the Michaelis-Gutman bodies, are pathognomonic. We report a case of cutaneous malakoplakia in a 77-year-old male with pyoderma gangrenosum and a 2-year history of a non-healing malleolar ulcer treated successfully with cotrimoxazole.
Subject(s)
Immunocompromised Host , Malacoplakia/drug therapy , Malacoplakia/etiology , Pyoderma Gangrenosum/complications , Pyoderma Gangrenosum/drug therapy , Administration, Cutaneous , Aged , Humans , Male , Treatment OutcomeABSTRACT
Os autores relatam um caso de malacoplasia acometendo o intestino grosso, bexiga e retropertônio, doença rara, principalmente pelo comprometimento de mais de um órgäo. Trata-se do segundo caso observado em nosso Serviço, envolvendo os mesmos órgäos. Estudam os meios diagnósticos e terapêuticos e däo ênfase à associaçäo sulfametoxazol-trimetoprim (SMZ-TM) e ácido ascórbico, que se mostrou eficiente a longo prazo na resoluçäo da enfermidade
Subject(s)
Humans , Male , Adult , Retroperitoneal Space/pathology , Intestine, Large/pathology , Malacoplakia/diagnosis , Urinary Bladder/pathology , Ascorbic Acid/therapeutic use , Anti-Infective Agents/therapeutic use , Malacoplakia/drug therapy , Malacoplakia/pathology , Malacoplakia/surgery , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic useSubject(s)
Humans , Male , Adult , AIDS-Related Opportunistic Infections , AIDS-Related Opportunistic Infections/classification , AIDS-Related Opportunistic Infections/complications , AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/drug therapy , AIDS-Related Opportunistic Infections/epidemiology , AIDS-Related Opportunistic Infections/etiology , AIDS-Related Opportunistic Infections/physiopathology , AIDS-Related Opportunistic Infections/therapy , Malacoplakia/classification , Malacoplakia/complications , Malacoplakia/diagnosis , Malacoplakia/drug therapy , Malacoplakia/epidemiology , Malacoplakia/etiology , Malacoplakia/physiopathology , Malacoplakia/surgery , Malacoplakia/therapyABSTRACT
Apresentamos um caso de malacoplasia do estômago. Analisamos os aspectos clínicos, anatomopatológicos e etiopatogênicos. Chamamos atençäo para sua raridade e achado casual no transoperatório
Subject(s)
Humans , Female , Aged , Stomach/physiopathology , Gastrointestinal Neoplasms/complications , Malacoplakia , Colonic Neoplasms/complications , Brazil , Malacoplakia/diagnosis , Malacoplakia/drug therapy , Malacoplakia/etiology , Malacoplakia/physiopathologyABSTRACT
Os autores relatam um caso de malacoplasiia acometendo o intestino grosso, bexiga e retroperitônio, patologia essa bastante rara, principalmente pelo acometimento de mais de um órgäo. Trata-se de caso único em nosso meio, onde já foram descritos dois outros, porém limitados a um único local. Estudam os meios terapêuticos e däo ênfase à associaçäo sulfametoxazol-trimetoprim (SMZ-TM) e ácido ascórbico, que se mostrou eficiente na resoluçäo do proesente caso
Subject(s)
Humans , Adolescent , Female , Malacoplakia/diagnosis , Barium Sulfate , Enema , Malacoplakia/drug therapy , Urinary Bladder/pathology , UrographyABSTRACT
We studied 5 children with intestinal malakoplakia who were seen during a period of 10 years. Four were male and one female. The main clinical manifestations were: chronic bloody and mucous diarrhea, abdominal pain and polypoid masses detected by rectal maneuver. Either the radiological study as well as endoscopy showed the presence of stenosis and polypoid masses (pseudopolyps). Two patients underwent laparotomy and a tumoral infiltration at the level of rectal-sigmoid and cecal appendix was found. Histological diagnosis proves to be definitive in these case. Drug treatment has been with bethanechol, trimethoprim-sulfamethoxazole in three patients. We conclude that intestinal malakoplakia is more common that ulcerative colitis in our children population attending at this institute. Therefore, the presence of intestinal malakoplakia must be ruled out in every child having chronic bloody and mucous diarrhea, presenting as well pseudopolyps.
Subject(s)
Intestinal Diseases , Malacoplakia , Adolescent , Child , Child, Preschool , Female , Humans , Intestinal Diseases/complications , Intestinal Diseases/diagnosis , Intestinal Diseases/drug therapy , Intestinal Diseases/microbiology , Malacoplakia/complications , Malacoplakia/diagnosis , Malacoplakia/drug therapy , Malacoplakia/microbiology , MaleABSTRACT
Os autores apresentam 01 caso de malacoplaquia renal em paciente do sexo masculino que foi tratado com nefrectomia com diagnóstico pré-operatório de neoplasia renal.
Subject(s)
Malacoplakia , Malacoplakia/diagnosis , Malacoplakia/drug therapyABSTRACT
La malacoplaquia es una patología benigna que en ocasiones puede tener comportamiento maligno como lo es el caso de este informe de un varón de 45 años de edad que falleció por causa de esta enfermedad, y en el cual las diversas biopsias tomadas muestran las distintas etapas evolutivas de esta patología, en la cual existe un defecto en el 3,5, guanosinmonofosfato cíclico que perturba la capacidad fagocitaria de la célula permitiendo la situación intracelular de la E. Coli, según este principio, el tratamiento con colinérgicos del tipo del betanecol añadidos al uso del trimetropim con sulfametoxazol parece ser lo más recomendable hasta el momento