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1.
Rev. Soc. Bras. Clín. Méd ; 10(1)jan.-fev. 2012.
Article in Portuguese | LILACS | ID: lil-612010

ABSTRACT

JUSTIFICATIVA E OBJETIVOS: As meningites assépticas (MA) representam a grande maioria das meningites presentes em nosso meio. Os principais causadores dessa doença são os enterovírus. O quadro clínico caracteriza-se por cefaleia, fotofobia, sinais de irritação meníngea, náuseas, vômitos e febre. A grande dificuldade diagnóstica é que estes mesmos sintomas são encontrados nos quadros de meningites bacterianas, mais graves, demandando condutas mais agressivas. O objetivo deste estudo foi rever o assunto, destacando o manuseio dos casos suspeitos bem como suas etiologias e fisiopatologias. CONTEÚDO: Conceitos de MA, suas etiologias virais e não virais, incluindo àquelas causadas pela utilização de medicamentos. CONCLUSÃO: Devido às sobreposições sintomatológicas, introduziu-se empiricamente a antibioticoterapia intra-hospitalar no momento da suspeita de infecção meníngea, observando a evolução clínico-laboratorial do paciente.


BACKGROUND AND OBJECTIVES: The aseptic meningitis (AM) representing the vast majority of meningitis in our society. The main cause of this disease is the enteroviruses. The clinical picture is characterized by headache, photophobia, and signs of meningeal irritation, nausea, vomiting and fever. The diagnostic difficulty is that these same symptoms are found in the tables of bacterial meningitis, the most serious, demanding more aggressive treatment. This article aims to review the issue, emphasizing the management of suspected cases as well as its etiology and pathophysiology. CONTENTS: Address the concept of AM, its viral and nonviral etiologies, including those caused by medication use. CONCLUSION: Due to the overlap of the symptoms, we introduced an empirical intrahospital antibiotic treatment at the moment we suspect meningeal infection, observing the evolution of clinical and laboratory signs.


Subject(s)
Humans , Cerebrospinal Fluid , Meningism/diagnosis , Meningism/physiopathology , Meningitis, Aseptic/diagnosis , Meningitis, Aseptic/physiopathology
3.
Rev. chil. infectol ; Rev. chil. infectol;13(1): 41-5, 1996. tab
Article in Spanish | LILACS | ID: lil-202652

ABSTRACT

Durante el año 1993 se presentó un aumento de 3 veces el número promedio de casos de meningitis asépticas en el Hospital Roberto del Río. Se presentan las características clínicas de 50 niños mayores con meningitis aséptica, y se detallan las de 16 casos de ellos con diagnóstico comprobado de meningitis por enterovirus. El cuadro clínico fue benigno, no hubo complicaciones, muerte o secuelas al alta. Dentro de los hallazgos de laboratorio, se destaca el promedio de neutrófilos en el 30 por ciento de los casos en la punción lumbar de control,luego de 24 horas o más de evolución de la enfermedad.El echovirus 30 fue el enterovirus predominante. Se comparan los hallazgos con la literatura, y se comenta la utilidad de una segunda punción lumbar en casos como éstos


Subject(s)
Humans , Male , Female , Enterovirus Infections/physiopathology , Enterovirus/pathogenicity , Meningitis, Aseptic/physiopathology , Meningitis, Viral/physiopathology , Cerebrospinal Fluid/virology
4.
J Pediatr ; 121(2): 291-4, 1992 Aug.
Article in English | MEDLINE | ID: mdl-1640301

ABSTRACT

The assessment of the blood-brain barrier permeability (BBBP) showed that BBBP values were higher in stressed neonates and those with bacterial meningitis than in "healthy" infants or neonates with aseptic meningitis. The BBBP determination may be helpful in differentiating bacterial from aseptic meningitis; the high BBBP should be considered in the management of stressed neonates.


Subject(s)
Blood-Brain Barrier/physiology , Infant, Newborn/physiology , Meningitis, Aseptic/physiopathology , Meningitis, Bacterial/physiopathology , Stress, Physiological/physiopathology , Asphyxia Neonatorum/physiopathology , Diagnosis, Differential , Heart Defects, Congenital/physiopathology , Humans , Meningitis, Aseptic/diagnosis , Meningitis, Bacterial/diagnosis , Permeability
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