ABSTRACT
Guitarfishes and sawfishes are included in the order Rhinopristiformes, which currently encompasses five families: Pristidae, Rhinobatidae, Trygonorrhinidae, Rhinidae and Glaucostegidae. Considering the low number of studies focused on oral structures in Rhinopristiformes and the need to better understand their internal morphology, this study aimed to (1) evaluate and describe the morphological variation of the oropharyngeal denticles of guitarfishes and sawfish; (2) evaluate and describe the ontogenetic and sexual variation of the oropharyngeal denticles of Zapteryx brevirostris; (3) propose characters potentially useful for taxonomic and systematic purposes and (4) discuss the possible functions and advantages of these structures. Tissue samples were taken from the oropharyngeal region of specimens preserved in 70% alcohol and then prepared for visualization in scanning electron microscopy. A new method for sampling the pharynx region is proposed herein. Considerable morphological variation between families and genera was observed. However, no variation between conspecifics was found. Regional variations of denticles when examining a single individual were observed in shape, ornamentation, and orientation. In Zapteryx brevirostris, males had a significantly higher density of denticles in the ventral region than females and lower densities were observed in juveniles. The four characters discussed here are based on the presence of keels, number of cusps, distal end elongation and width/length ratio of the oropharyngeal denticles. Among the possible functions and advantages of these structures are the improvement of food adherence, tissue protection against food abrasion and parasitism, and attenuation of hydrodynamic drag in the oropharyngeal cavity during food ingestion.
Subject(s)
Oropharynx , Animals , Oropharynx/anatomy & histology , Oropharynx/physiology , Male , Female , Microscopy, Electron, ScanningABSTRACT
PURPOSE: Literature review on the onset locations of the pharyngeal phase of swallowing in asymptomatic and symptomatic adults and elderly people. RESEARCH STRATEGIES: Research was conducted in the PubMed, BIREME and SciELO databases through the descriptors fluoroscopy (fluoroscopia), deglutition (deglutição) and pharynx (faringe). SELECTION CRITERIA: Studies published between 2005 and 2015, carried out with adults and elderly people who underwent swallowing videofluoroscopy (SVF), and citing the onset location of the pharyngeal phase of swallowing. DATA ANALYSIS: Descriptive analysis and meta-analysis were performed, evaluating the heterogeneity and the measures grouped with random effects through I2 statistics. For ratio calculation in the meta-analysis, the locations described in the articles were classified according to the Modified Barium Swallowing protocol - Measurement Tool for Swallowing Impairment (MBSImp). RESULTS: Twelve articles were selected for descriptive analysis and seven for meta-analysis. Heterogeneity was found between studies, especially due to clinical and methodological differences. The random effect indicated predominance (58%) of the onset of the pharyngeal phase of swallowing at levels 0 and 1 of the MBSImP. In asymptomatic individuals, the onset of the pharyngeal phase was observed in the oral cavity, base of the tongue, dorsum of the tongue and vallecula. In symptomatic individuals, onset was mainly observed in the oropharynx, vallecula, hypopharynx and pyriform sinus. CONCLUSION: We noted a greater frequency of the onset of the pharyngeal phase of swallowing in the vallecula. The onset of the pharyngeal phase in the hypopharynx and pyriform sinus was more often observed among elderly individuals or with comorbidities that could alter swallowing.
Subject(s)
Deglutition Disorders/physiopathology , Deglutition/physiology , Pharynx/physiology , Adult , Aged , Female , Fluoroscopy , Humans , Male , Oropharynx/physiologyABSTRACT
RESUMO Objetivo Revisar a literatura quanto aos locais de início da fase faríngea da deglutição em adultos e idosos, assintomáticos e sintomáticos. Estratégia de pesquisa Foi realizada pesquisa nas bases PubMed, BIREME e SciELO através dos descritores fluoroscopia (fluoroscopy), deglutição (deglutition) e faringe (pharynx). Critérios de seleção Estudos publicados entre 2005 e 2015, com adultos e idosos que realizaram videofluoroscopia da deglutição (VFD) e citaram o local de início da fase faríngea da deglutição. Análise dos dados Foi realizada análise descritiva e meta-análise, com estudo da heterogeneidade e de medidas agrupadas com efeito aleatório por meio da estatística I2. Para o cálculo de proporção na meta-análise, os locais descritos nos artigos foram classificados pelo Modified Barium Swallowing - Measurement Tool for Swallowing Impairment (MBSImp). Resultados Ao final, foram selecionados 12 artigos para análise descritiva e sete para meta-análise. Foi encontrada heterogeneidade entre os estudos, especialmente, devido às diferenças clínicas e metodológicas. O efeito aleatório indicou predominância (58%) do início da fase faríngea da deglutição nos níveis zero e um do MBSImP. Em indivíduos assintomáticos, observou-se o início da fase faríngea na cavidade oral, base da língua, dorso da língua e valécula. Em indivíduos sintomáticos, o início foi observado, principalmente, em orofaringe, valécula, hipofaringe e recessos piriformes. Conclusão Foi observada maior frequência de início da fase faríngea da deglutição em valécula. O início da fase faríngea em hipofaringe e recessos piriformes foi mais observado em indivíduos idosos ou com comorbidades que poderiam alterar a deglutição.
ABSTRACT Purpose Literature review on the onset locations of the pharyngeal phase of swallowing in asymptomatic and symptomatic adults and elderly people. Research strategies Research was conducted in the PubMed, BIREME and SciELO databases through the descriptors fluoroscopy (fluoroscopia), deglutition (deglutição) and pharynx (faringe). Selection criteria Studies published between 2005 and 2015, carried out with adults and elderly people who underwent swallowing videofluoroscopy (SVF), and citing the onset location of the pharyngeal phase of swallowing. Data analysis Descriptive analysis and meta-analysis were performed, evaluating the heterogeneity and the measures grouped with random effects through I2 statistics. For ratio calculation in the meta-analysis, the locations described in the articles were classified according to the Modified Barium Swallowing protocol - Measurement Tool for Swallowing Impairment (MBSImp). Results Twelve articles were selected for descriptive analysis and seven for meta-analysis. Heterogeneity was found between studies, especially due to clinical and methodological differences. The random effect indicated predominance (58%) of the onset of the pharyngeal phase of swallowing at levels 0 and 1 of the MBSImP. In asymptomatic individuals, the onset of the pharyngeal phase was observed in the oral cavity, base of the tongue, dorsum of the tongue and vallecula. In symptomatic individuals, onset was mainly observed in the oropharynx, vallecula, hypopharynx and pyriform sinus. Conclusion We noted a greater frequency of the onset of the pharyngeal phase of swallowing in the vallecula. The onset of the pharyngeal phase in the hypopharynx and pyriform sinus was more often observed among elderly individuals or with comorbidities that could alter swallowing.
Subject(s)
Humans , Male , Female , Adult , Aged , Pharynx/physiology , Deglutition Disorders/physiopathology , Deglutition/physiology , Oropharynx/physiology , FluoroscopyABSTRACT
ABSTRACT INTRODUCTION: During the aging process, one of the functions that changes is swallowing. These alterations in oropharyngeal swallowing may be diagnosed by methods that allow both the diagnosis and biofeedback monitoring by the patient. One of the methods recently described in the literature for the evaluation of swallowing is the Sonar Doppler. OBJECTIVE: To compare the acoustic parameters of oropharyngeal swallowing between different age groups. METHODS: This was a field, quantitative, study. Examination with Sonar Doppler was performed in 75 elderly and 72 non-elderly adult subjects. The following acoustic parameters were established: initial frequency, first peak frequency, second peak frequency; initial intensity, final intensity; and time for the swallowing of saliva, liquid, nectar, honey, and pudding, with 5- and 10-mL free drinks. RESULTS: Objective, measurable data were obtained; most acoustic parameters studied between adult and elderly groups with respect to consistency and volume were significant. CONCLUSION: When comparing elderly with non-elderly adult subjects, there is a modification of the acoustic pattern of swallowing, regarding both consistency and food bolus volume.
RESUMO INTRODUÇÃO: Durante o processo de envelhecimento, uma das funções que sofre modificação é a deglutição. Estas alterações na deglutição orofaríngea podem ser diagnosticadas por métodos que permitem tanto o diagnóstico quanto o monitoramento e biofeedback ao indivíduo. Um dos métodos descrito na literatura recentemente para a avaliação da deglutição é o Sonar Doppler. OBJETIVO: O objetivo desse estudo foi comparar os parâmetros acústicos da deglutição orofaríngea entre faixas etárias distintas. MÉTODO: Estudo de campo, quantitativo. O exame com o Sonar Doppler foi aplicado em 75 idosos e 72 adultos. Estabeleceram-se os parâmetros acústicos: frequência inicial, frequência do primeiro pico, frequência do segundo pico, intensidade inicial, intensidade final e tempo, para as deglutições de saliva, liquido, néctar, mel e pudim, com gole livre, 5 mL e 10 mL. RESULTADOS: Obtiveram-se dados objetivos e mensuráveis, apresentando significância para a maioria dos parâmetros acústicos estudados entre o grupo de idosos e adultos em relação à consistência e volume. CONCLUSÃO: Verificamos que há modificação do padrão acústico da deglutição, tanto em relação à consistência quanto a volume do bolo alimentar, quando comparados adultos idosos e não idosos.
Subject(s)
Adolescent , Adult , Aged , Humans , Middle Aged , Young Adult , Acoustics , Deglutition/physiology , Oropharynx/physiology , Age Factors , Doppler Effect , Speech Acoustics , Surveys and Questionnaires , Voice QualityABSTRACT
INTRODUCTION: During the aging process, one of the functions that changes is swallowing. These alterations in oropharyngeal swallowing may be diagnosed by methods that allow both the diagnosis and biofeedback monitoring by the patient. One of the methods recently described in the literature for the evaluation of swallowing is the Sonar Doppler. OBJECTIVE: To compare the acoustic parameters of oropharyngeal swallowing between different age groups. METHODS: This was a field, quantitative, study. Examination with Sonar Doppler was performed in 75 elderly and 72 non-elderly adult subjects. The following acoustic parameters were established: initial frequency, first peak frequency, second peak frequency; initial intensity, final intensity; and time for the swallowing of saliva, liquid, nectar, honey, and pudding, with 5- and 10-mL free drinks. RESULTS: Objective, measurable data were obtained; most acoustic parameters studied between adult and elderly groups with respect to consistency and volume were significant. CONCLUSION: When comparing elderly with non-elderly adult subjects, there is a modification of the acoustic pattern of swallowing, regarding both consistency and food bolus volume.
Subject(s)
Acoustics , Deglutition/physiology , Oropharynx/physiology , Adolescent , Adult , Age Factors , Aged , Doppler Effect , Humans , Middle Aged , Speech Acoustics , Surveys and Questionnaires , Voice Quality , Young AdultABSTRACT
A doença falciforme (DF) possui prevalência mundial elevada e manifestação clinicamente variável, sendo que as infecções constituem risco elevado e causa de óbito nas crianças diagnosticadas com anemia falciforme (HbSS). A colonização da nasofaringe pode ser fator importante para a ocorrência de doença local ou sistêmica. O Streptococcus pneumoniae é um patógeno de importância epidemiológica mundial e causador de infecções entre os pacientes com DF. A prevalência da colonização pelo pneumococo em nasofaringe varia de acordo com a população estudada e condições ambientais. O Staphylococcus aureus também pode colonizar a nasofaringe, além de causar infecção de pele e tecidos moles, pneumonia, septicemia e infecções ósteo-articulares. Diferentes biomarcadores têm sido associados à modulação clínica na DF e eles são comumente associados à hemólise e inflamação. O presente estudo teve como objetivo estabelecer o perfil de biomarcadores em indivíduos com DF associando-os ao perfil de colonização nasofaríngea e orofaríngea, com ênfase para os marcadores de infecção e hemólise que possam estar associados ao prognóstico clínico dda doença. As análises bioquímicas foram realizadas para a avaliação do perfil lipídico, hepático, inflamatório e hemolítico; marcadores clássicos de biologia molecular, como a talassemia α, os haplótipos ligados aos genes da globina beta e os polimorfismos no gene da mieloperoxidase foram também investigados. Desta forma, foi desenvolvido um estudo de corte transversal, com casuística composta por 154 pacientes com DF em idade pediátrica e em estado estável da doença, sendo 68,2% (105/154) HbSS e 31,8% (49/154) com doença SC (HbSC), todos provenientes do estado da Bahia. As crianças HbSS apresentaram diferenças significativas na grande maioria das variáveis laboratoriais analisadas e associadas ao metabolismo lipídico, renal, hepático e à hemólise e inflamação, quando comparadas ao grupo HbSC e ao controle saudável. A colonização em nasofaringe/orofaringe pelo S. pneumoniae esteve presente em 14 (9,6%) pacientes e pelo S. aureus em 81(56,6%) pacientes. Quanto ao perfil de sensibilidade dos isolados de pneumococos da população estudada, não foi observado o aumento da resistência pneumocócica à penicilina. A avaliação de modelos de análise multivariada demonstrou que a presença de colonização nasofaríngea e orofaríngea esteve associada à ocorrência de infecção juntamente com a contagem de leucócitos, sendo que o genótipo exibido pelo paciente foi fator de risco para a ocorrência de pneumonia. Os mesmos modelos apontaram o envolvimento dos polimorfonucleares neutrófilos na ocorrência de vaso-oclusão. Os resultados demonstram que os pacientes colonizados em nasofaringe pelo S. pneumoniae e pelo S. aureus apresentaram elevação dos valores de HCM, VCM, AST, ALT e Ferritina; investigações rotineiras de biomarcadores clássicos associados ao estudo da colonização de nasofaringe e orofaringe podem ter papel importante no acompanhamento da evolução clinica de indivíduos com DF, uma vez que os achados significativos sugerem que a presença de colonização tem papel importante na modulação dos eventos hemolítico, inflamatório e infeccioso presentes na doença.
Subject(s)
Humans , Child , Hemoglobin SC Disease/immunology , Nasopharynx/physiology , Oropharynx/physiology , Staphylococcus aureus/pathogenicity , Streptococcus pneumoniae/immunologyABSTRACT
BACKGROUND: the absence or delay of the swallowing reflex is considered a significant sign of dysphagia. Therefore, the therapy traditionally applied to these cases consists in increasing the intra-oral input through cold touches (0 or 00 larynx mirror) on the inferior portion of the inferior third of the palatoglossus arch. AIM: to identify in healthy young individuals which oropharyngeal regions are more sensitive and which stimulus is more efficient in triggering the swallowing reflex. METHODS: the swallowing reflex was analyzed based on the following stimuli: spatula, cold 00 larynx mirror, gauze embedded in cold water wrapped onto spatula and frozen moist gauze wrapped onto spatula; touching the palatoglossus arch in both its inferior and superior portions, the palatine tonsils, the base of the tongue and the uvula in 65 healthy young individuals. RESULTS: the swallowing reflex was not triggered in most of the participants when touching different oropharyngeal regions with different stimuli. This result was statistically significant. When present, the most efficient stimuli were cold 00 larynx mirror (28.6%) and frozen moist gauze wrapped onto spatula (27.3%). Concerning the oropharynx, the uvula (29.6%), the palatine tonsils (26.7%), the superior (25%) and inferior (21.2%) palatoglossi arches and the base of tongue (25%) were most sensitive to the applied stimuli. CONCLUSION: when the swallowing reflex was present, the uvula, the palatoglossi arches and the palatine tonsils were the most sensitive regions to trigger this reflex, and the most efficient stimuli to trigger swallowing were the cold 00 larynx mirror and the frozen moist gauze wrapped onto spatula.
Subject(s)
Deglutition Disorders/diagnosis , Deglutition/physiology , Oropharynx/physiology , Reflex/physiology , Adolescent , Adult , Body Temperature , Cold Temperature , Confidence Intervals , Diagnostic Equipment , Female , Humans , Male , Palatine Tonsil/physiology , Physical Stimulation/instrumentation , Tongue/physiology , Uvula/physiology , Young AdultABSTRACT
TEMA: a ausência ou atraso do reflexo da deglutição é considerado um sinal significativo de disfagia. Assim, a terapia tradicionalmente empregada nesses casos consiste em aumentar o input intra-oral por meio de toques gelados (espelho laríngeo 0 ou 00) no terço inferior do arco palatoglosso, porção inferior. OBJETIVOS: identificar, em indivíduos jovens e sadios, quais regiões da orofaringe são mais sensíveis para desencadear o reflexo da deglutição e qual estímulo é mais eficiente. MÉTODO: O reflexo da deglutição foi investigado a partir dos estímulos: espátula, espelho laríngeo 00 gelado, espátula envolta em gaze com água gelada e espátula envolta em gaze umedecida congelada, tocando-se o arco palatoglosso em suas porções inferior e superior, as tonsilas palatinas, a base de língua e a úvula em 65 indivíduos jovens e sadios. RESULTADOS: o reflexo da deglutição não foi desencadeado na maioria dos participantes quando tocado com diferentes estímulos e locais da orofaringe, sendo esta estatisticamente significante. Quando presente, os estímulos mais eficientes foram o espelho laríngeo 00 (28,6 por cento) e a espátula envolta com gaze congelada (27,3 por cento). Quanto à região da orofaringe, a úvula (29,6 por cento), as tonsilas palatinas (26,7 por cento), os arcos palatoglossos região superior (25 por cento) e inferior (21,2 por cento) e base de língua (25 por cento) foram sensíveis aos estímulos. CONCLUSÃO: quando presente o reflexo da deglutição, a úvula, os arcos palatoglossos e as tonsilas palatinas foram as regiões mais sensíveis para desencadeá-lo e o estímulo mais eficiente, dentre os selecionados, foram o espelho laríngeo gelado e a espátula envolta em gaze umedecida congelada.
BACKGROUND: the absence or delay of the swallowing reflex is considered a significant sign of dysphagia. Therefore, the therapy traditionally applied to these cases consists in increasing the intra-oral input through cold touches (0 or 00 larynx mirror) on the inferior portion of the inferior third of the palatoglossus arch. AIM: to identify in healthy young individuals which oropharyngeal regions are more sensitive and which stimulus is more efficient in triggering the swallowing reflex. METHODS: the swallowing reflex was analyzed based on the following stimuli: spatula, cold 00 larynx mirror, gauze embedded in cold water wrapped onto spatula and frozen moist gauze wrapped onto spatula; touching the palatoglossus arch in both its inferior and superior portions, the palatine tonsils, the base of the tongue and the uvula in 65 healthy young individuals. RESULTS: the swallowing reflex was not triggered in most of the participants when touching different oropharyngeal regions with different stimuli. This result was statistically significant. When present, the most efficient stimuli were cold 00 larynx mirror (28.6 percent) and frozen moist gauze wrapped onto spatula (27.3 percent). Concerning the oropharynx, the uvula (29.6 percent), the palatine tonsils (26.7 percent), the superior (25 percent) and inferior (21.2 percent) palatoglossi arches and the base of tongue (25 percent) were most sensitive to the applied stimuli. CONCLUSION: when the swallowing reflex was present, the uvula, the palatoglossi arches and the palatine tonsils were the most sensitive regions to trigger this reflex, and the most efficient stimuli to trigger swallowing were the cold 00 larynx mirror and the frozen moist gauze wrapped onto spatula.
Subject(s)
Adolescent , Adult , Female , Humans , Male , Young Adult , Deglutition Disorders/diagnosis , Deglutition/physiology , Oropharynx/physiology , Reflex/physiology , Body Temperature , Confidence Intervals , Cold Temperature , Diagnostic Equipment , Palatine Tonsil/physiology , Physical Stimulation/instrumentation , Tongue/physiology , Uvula/physiology , Young AdultABSTRACT
Although stroke affects mainly the oral and pharyngeal phases of swallowing, it may also impair esophageal contractions. Our hypothesis is that stroke may affect esophageal transit. The oral, pharyngeal, and esophageal transit was studied by the scintigraphic method in 26 patients (age range=26-83 years), eight of whom had mild dysphagia but all were able to feed orally and who had suffered an acute first-ever ischemic stroke 10-56 days (median = 43 days) before transit evaluation. The control group included 15 healthy volunteers (age range=27-86 years). All subjects swallowed a 5-ml liquid bolus and a 5-ml paste bolus labeled with technetium-99m phytate while sitting in front of the collimator of a gamma camara. The oral, pharyngeal, and proximal, middle, and distal esophageal transit was measured for 20 s. Three patients did not swallow the bolus during the scintigraphic evaluation. There was no difference between patients and controls with respect to oral and pharyngeal transit or clearance of liquid. For paste, the pharyngeal transit time was shorter for patients (0.48+/-0.17 s) than for controls (0.61+/-0.18 s, p=0.027). Also for the paste bolus, the residue in the mouth was greater in patients (18.4+/-13.6%) than in controls (10.2+/-4.9%, p=0.031). The liquid transit duration in the distal esophagus was shorter in patients with stroke (1.74+/-0.84 s) than in controls (2.68+/-1.65 s, p=0.028). There was no difference between patients and controls in esophageal residue. In conclusion, patients with stroke and able to feed orally may have alterations in the esophageal transit of a liquid bolus.
Subject(s)
Esophageal Motility Disorders/diagnostic imaging , Esophageal Motility Disorders/etiology , Oropharynx/physiology , Radionuclide Imaging/methods , Stroke/complications , Adult , Aged , Aged, 80 and over , Esophageal Motility Disorders/diagnosis , Female , Humans , Male , Middle Aged , Radiography , Time FactorsABSTRACT
Objetivo: verificar a incidência e o grau de disfagia orofaríngea em indivíduos internados em Unidade de Terapia Intensiva (UTI) e Semi-Intensiva, correlacionando os achados com a doença de base. Métodos: nesse estudo foram avaliados 25 pacientes da UTI e Semi-UTI do Hospital Centro MédicoMaranhense. Os dados foram colhidos por meio de um protocolo de avaliação fonoaudiológica. Resultados: dos 25 pacientes avaliados 18 (74%) apresentaram disfagia orofaríngea, sendo que 11 (61%) tiveram como doença de base lesão neurológica, e 7 (39%) tiveram como doença de base acometimentos não neurológicos. Houve associação significante entre a presença de disfagia e doença de base neurológica. Dos 18 pacientes disfágicos, 8 (45%) apresentaram disfagia de grau leve, 4 (22%)disfagia de grau moderado e 6 (33%) disfagia de grau grave. Deste total, dos pacientes com doença de base neurológica: 03 (27%) apresentaram grau leve, 03 (27%) apresentaram grau moderado e 05 (46%) pacientes apresentaram grau grave. Já os pacientes acometidos por doença de base não neurológica apresentaram: grau leve 05 pacientes (72%), grau moderado 01 paciente (14%) e graugrave 01 paciente (14%). Conclusão: os dados apontam alta incidência de quadros de disfagia orofaríngea em pacientes internados na Unidade de Terapia Intensiva e Semi-intensiva, com associação significante entre a presença de disfagia e doença de base neurológica; o grau grave de disfagiaorofaríngea foi predominante nas doenças de base neurológica, e o grau leve de disfagia orofaríngea foi predominante nas doenças de base não neurológica.
Purpose: to check the incidence and the grade of oropharyngeal dysphagia in individuals under intensive and almost intensive therapy, correlating the data with what was found about the base ill. Methods: in this project, 25 patients from intensive therapy and almost intensive therapy were available from Centro Médico Maranhense Hospital. The information was collected with a speech therapy evaluation. Results: from 25 patients evaluated, 18 (74%) showed oropharyngeal dysphagia, 11 (61%) had as base a neurological ill, and 7 (39%) had as base a non-neurological ill. From 18 patients that had dysphagia,8 (45%) showed a little grade of dysphagia, 4(22%) moderate grade of dysphagia and 6 (33%) a serious grade of dysphagia. About the patients without a neurological base ill problem: light grade 5 patients (72%), moderate grade 01 patient (14%) and had acute grade 01 patient (14%). Conclusion:with the analysis and conclusions obtained, this project show high incidence of oropharyngeal dysphagiain patients at the hospital. In the association and relation between a neurological ill and grade of oropharyngeal dysphagia, the acute grade was predominant, as for the association of patients withouta neurological ill and the grade of oropharingeal dysphagia, the minor showen grade was predominant.
Subject(s)
Humans , Male , Female , Intensive Care Units , Oropharynx/physiology , Deglutition Disorders/diagnosis , Chi-Square Distribution , Nervous System Diseases/complications , Nervous System Diseases/diagnosis , Deglutition Disorders/etiologyABSTRACT
OBJECTIVE: Patients with iron deficiency may have reduced power of the pharyngeal muscle for bolus propulsion into the esophagus. We hypothesized that esophageal muscle is similarly impaired. METHODS: We studied the oropharyngeal and esophageal transits and esophageal motility of 12 patients (11 women) aged 31-50 yr (median 36 yr) with iron deficiency anemia (serum iron less than 40 microg/dl) and 17 normal volunteers (16 women) aged 26-52 yr (median 37 yr) with serum iron greater than 60 microg/dl. The esophageal motility was studied by the manometric method, with continuous perfusion and 10 swallows of a 2-ml bolus of water alternated with 10 swallows of a 7-ml bolus; and the oropharyngeal and esophageal transits were studied by scintigraphy, with swallows of a 10-ml bolus for the study of oropharyngeal transit and of a 10-ml bolus for the study of esophageal transit. Motility and transit were studied in the supine position. RESULTS: The amplitude, duration and area under the curve of contractions were lower in patients than in volunteers. There were no differences in peristaltic contraction velocity, lower esophageal sphincter pressure, and lower esophageal sphincter relaxation duration. There was no difference in oropharyngeal transit. In the esophagus the transit was slower in patients than in volunteers. The time needed by the scintigraphic activity to reach a peak in the proximal esophagus was longer in patients than in volunteers. CONCLUSIONS: Iron deficiency may decrease esophageal contractions and impair esophageal transit.
Subject(s)
Anemia, Iron-Deficiency/physiopathology , Deglutition Disorders/physiopathology , Esophagus/physiology , Oropharynx/physiology , Pharyngeal Muscles/physiopathology , Adult , Anemia, Iron-Deficiency/diagnostic imaging , Area Under Curve , Deglutition/physiology , Deglutition Disorders/diagnostic imaging , Esophageal Motility Disorders/diagnostic imaging , Esophageal Motility Disorders/physiopathology , Esophagogastric Junction/diagnostic imaging , Esophagogastric Junction/physiopathology , Esophagus/diagnostic imaging , Female , Gastrointestinal Transit , Humans , Male , Manometry/methods , Middle Aged , Oropharynx/diagnostic imaging , Peristalsis , Pharyngeal Muscles/diagnostic imaging , Radionuclide ImagingABSTRACT
UNLABELLED: After being ingested, food and liquids suffer a thermal regulation process, which adapts them immediately to the body temperature by means of the mucosa diffusion. We have not found bibliographical information about this matter yet. OBJECTIVES: 1) To describe the reaction of the oropharynx area and the esophagus by heat and coldness. 2) To compare both areas reaction. STUDY POPULATIONS: Six patients (three men, three women, Age: mean 42 years old, SD 11.8), healthy individuals without both gastrointestinal and systemic disease that could after microcirculation. MATERIALS & METHODS: Temperature measurement of liquid at mouth entrance and at 24 cm and 38 cm from dentary superior arcade using two thermocouples. Deglution of 40 ml of hot water (X 60 degrees C at entrance) or cold water (X 4 degrees C) in two draughts. Temperature measurement at both thermocouples at the end of deglution (time = 0 (zero)) and every 10 seconds. Random sequences every 30 minutes. RESULTS: Using water at 60 degrees C, the temperature descended to 42 degrees C in the distal end. The oropharynx region dissipated 45% of the initial temperature while the esophagus completed the other 55%. The esophagus itself dissipated 65.6% of the 12.2 degrees C in time = 0 (zero). After 40 seconds the temperature reached the normal body temperature. In the case of the iced water (4 degrees C), the total work consisted on increasing temperature 33.6 degrees C to the normal corporal temperature. The 68.45% of the difference between the initial and the final temperature was obtained by the oropharynx region and the rest by the esophagus. In time = 0 (zero) the temperature increased up to 30 degrees C and the esophagus only contributed with 28.3% of the total work. The normal corporal temperature was reached after 40 seconds. It was observed a significant difference in the heating capacity between the oropharynx region and esophagus (p > 0.001). There was also a significant difference in the oesophagus itself between heat and coldness in time = 0 (zero) ¿65.6% (heat) Vs. 28.3% (coldness), 0.02 > p > 0.01¿ and values between time = 0 (zero) and 10-40 seconds (p > 0.001). CONCLUSION: 1) The ability of cooling was similar in both regions. 2) In the oropharynx region the capacity of heating was higher (voluntary time of deglution) than in the esophagus region. 3) The esophagus initial response before coldness was slower than oropharynx region's one. The buccal retention was greater. 4) Before both stimulus, normal corporal temperature was reached after 40 seconds. COMMENTARY: The isothermation of coldness and heat would work through the same mechanism: the mucosa vasodilatation and the increase of blood flow. This hypothesis would be valid for all the mucosa of the digestive tract. This mechanism could be altered in inflammatory diseases. Iced water washings on bleeding wounds be counter-productive. The persistence of extreme temperatures in the environment modifies the structure of the esophagus mienteric plexus (Auerbach's plexus). Frequent ingestion of fluids above 60 degrees C would be a predisponent factor for esophagus cancer.
Subject(s)
Body Temperature Regulation/physiology , Esophagus/physiology , Oropharynx/physiology , Vasodilation/physiology , Adult , Cold Temperature , Esophagus/blood supply , Female , Heating , Humans , Male , Middle Aged , Oropharynx/blood supply , Prospective StudiesABSTRACT
La funcionalidad respiratoria es extremadamente importante para el desarrollo del complejo nasomaxilar, además del desarrollo sistémico. Una respiración alterada y, en particular, una respiración de tipo bucal, tiene consecuencias específicas sobre todo el organismo. Estas han sido objeto de estudio en nuestra investigación, que se ha desarrollado con el auxilio de tres diferentes métodos rinomanométricos (rinomanometría anterior activa, rinomanometría posterior activa y rinomanometría posterior bilateral simultánea). Los resultados indican que los respiradores bucales tienen valores de resistencia nasal por encima de la media y que éstas disminuyen después del test dinámico de esfuerzo en los sujetos con patologías obstructivas de las primeras vías aéreas con base vasomotora. Se ha observado que una respiración no fisiológica está asociada a signos típicos (faciales, adenoidea, disturbios digestivos, alteraciones a nivel de columna y tórax) y una mayor susceptibilidad a las infecciones de las vías aéreas altas (amigdalitis, que pueden involucrar al oído medio (otitis) por la proximidad anatómica o llegar más profundamente (neumonías). Sería beneficioso examinar precozmente a los pacientes y someterlos a un plan de tratamiento adecuado que evitaría o haría menos grave la aparición de alteraciones irreversibles
Subject(s)
Manometry , Mouth Breathing/physiopathology , Respiration/physiology , Stomatognathic System/physiology , Digestive System/physiopathology , Circulatory and Respiratory Physiological Phenomena , Pituitary Gland/physiopathology , Hypoxia/physiopathology , Malocclusion/diagnosis , Maxillofacial Development , Nasopharynx/physiology , Nervous System/physiopathology , Nose/physiology , Oropharynx/physiology , Posture/physiology , Renal Circulation , Kidney/physiopathology , Somatotypes , Vertical DimensionSubject(s)
Feeding and Eating Disorders/physiopathology , Behavior Therapy , Child , Child, Preschool , Deglutition/physiology , Feeding Behavior/physiology , Feeding and Eating Disorders/diagnosis , Feeding and Eating Disorders/therapy , Humans , Infant , Infant, Newborn , Intestinal Absorption , Oropharynx/anatomy & histology , Oropharynx/physiology , Sucking Behavior/physiologyABSTRACT
Entre nove homens jovens voluntários sadios, estudou-se o efeito de deglutiçöes "secas", líquidas e de pasta na motilidade da faringe. Os líquidos tinham viscosidades de 200 centipoise (cP) e 300 cP e a pasta 60000 cP. O volume deglutido foi d=10 ml. Utilizou-se o método manométrico, com transdutores distanciados 1,5 cm, que registraram pressöes da face posterior da orofaringe, hipofaringe e esfíncter superior do esôfago (ESE). Também estudou-se a atividade eletromiográfica, dos musculos da regiäo intra-hióide. A amplitude e duraçäo da contraçäo na orofaringe e hipofaringe näo foi diferente entre os quatro tipos de deglutiçöes. A duraçäo foi menor na hipofaringe do que na orofaringe. A velocidade de propagaçäo do peristaltismo foi menor para a pasta. O aumento da viscosidade foi associado a maior duraçäo do relaxamento do ESE e maior pressäo durante a passagem do bolo alimentar pela hipofaringe e esfíncter. A duraçäo da atividade eletromiográfica dos músculos da regiäo infra-hióide foi mais longa para pasta do que para deglutiçöes "secas e líquidas. Os resultados indicam que a motilidade da faringe se modifica com a natureza do bolo alimentar deglutido, o que pode ter implicaçöes diagnóstica e terapêutica
Subject(s)
Humans , Male , Adult , Adolescent , Deglutition/physiology , Pharynx/physiology , Analysis of Variance , Electromyography , Food , Hypopharynx/physiology , Esophagogastric Junction/physiology , Manometry , Muscle Contraction , Oropharynx/physiology , Peristalsis , Pharyngeal Muscles , ViscosityABSTRACT
In 9 young men, healthy volunteers, we studied the effect of dry swallows, liquid and paste swallows on the pharyngeal motility. The viscosities of liquids and past were 200 centipoise (cP), 300 cP and 60000 cP, respectively. The bolus volume was 10 ml. For pharyngeal manometry we used two strain-gauge manometric probes taped together, so that a total of six transducers were staggered at 1.5 cm intervals. After its passage through the nose, the assembly was positioned so that all its transducers faced posteriorly, and manometric activity was recorded from oropharynx, hypopharynx and upper esophageal sphincter (UES). We also recorded infra-hyoid electromiographic activity. The amplitude and duration of the oropharyngeal and hypopharyngeal peristaltic pressure complex were not changed by the different boluses. The velocity of peristaltism propagation between oropharynx and UES was slower for paste than for liquids or dry swallows. The increased of viscosity was associated with longer duration of UES relaxation, and greater intrabolus pressure in hypopharynx and UES. The infra-hyoid electromiographic activity was longer for paste than for liquids or dry swallows. These findings suggest that pharyngeal motility is affected by the characteristics of the swallowed bolus.