ABSTRACT
Proliferative periostitis is a rare condition that can affect children and adolescents. It is characterized by the successive deposition of layers of bone caused by low-virulence infection or chronic inflammatory stimulation. The purpose of this paper is to report a case of proliferative periostitis in a pediatric patient, emphasizing the clinical and radiographic aspects as well as the therapeutic management.
Subject(s)
Periostitis/pathology , Child , Female , Humans , Periostitis/diagnostic imagingSubject(s)
Alprostadil/adverse effects , Bone Remodeling/physiology , Heart Transplantation , Hypoplastic Left Heart Syndrome/drug therapy , Periostitis/chemically induced , Alprostadil/therapeutic use , Follow-Up Studies , Humans , Hypoplastic Left Heart Syndrome/diagnostic imaging , Hypoplastic Left Heart Syndrome/surgery , Infant, Newborn , Infusions, Intravenous , Intensive Care Units, Pediatric , Lower Extremity , Male , Periostitis/diagnostic imaging , Periostitis/physiopathology , Radiography/methods , Risk Assessment , Time Factors , Withholding TreatmentABSTRACT
Chronic recurrent multifocal osteomyelitis is an idiopathic nonpyogenic autoinflammatory bone disorder involving multiple sites, with clinical progression persisting for more than 6 months and which may have episodes of remission and exacerbation in the long term. It represents up to 2-5% of the cases of osteomyelitis, with an approximate incidence of up to 4/1,000,000 individuals, and average age of disease onset estimated between 8-11 years, predominantly in females. The legs are the most affected, with a predilection for metaphyseal regions along the growth plate. We describe the case of a female patient, aged 2 years and 5 months, with involvement of the left ulna, right jaw and left tibia, showing a predominance of periosteal reaction as main finding.
Subject(s)
Osteomyelitis/diagnostic imaging , Osteomyelitis/pathology , Periostitis/diagnostic imaging , Periostitis/pathology , Biopsy , Child, Preschool , Female , Humans , Mandible/diagnostic imaging , Tibia/diagnostic imaging , Tibia/pathology , Tomography, X-Ray Computed , Ulna/diagnostic imaging , Ulna/pathologyABSTRACT
Summary Chronic recurrent multifocal osteomyelitis is an idiopathic nonpyogenic autoinflammatory bone disorder involving multiple sites, with clinical progression persisting for more than 6 months and which may have episodes of remission and exacerbation in the long term. It represents up to 2-5% of the cases of osteomyelitis, with an approximate incidence of up to 4/1,000,000 individuals, and average age of disease onset estimated between 8-11 years, predominantly in females. The legs are the most affected, with a predilection for metaphyseal regions along the growth plate. We describe the case of a female patient, aged 2 years and 5 months, with involvement of the left ulna, right jaw and left tibia, showing a predominance of periosteal reaction as main finding.
Resumo Osteomielite crônica multifocal recorrente é uma desordem autoinflamatória óssea idiopática não piogênica, envolvendo vários sítios e com evolução clínica persistindo por mais de 6 meses, podendo apresentar episódios de remissão e exacerbação em longo prazo. Representa de 2 a 5% das osteomielites, com incidência aproximada de até 4/1.000.000, com idade média de apresentação estimada entre 8 e 11 anos, predominando no gênero feminino. Os membros inferiores são os mais afetados, com predileção para regiões metafisárias junto à fise. Descrevemos um caso da doença em uma menina de 2 anos e 5 meses de idade, com acometimento de ulna esquerda, mandíbula à direita e tíbia esquerda, exibindo predomínio de reação periosteal como achado principal.