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1.
J Foot Ankle Surg ; 2024 Sep 01.
Article in English | MEDLINE | ID: mdl-39222874

ABSTRACT

The aim of the study was to investigate the effectiveness of radial and focus (extracorporeal shock wave therapy) ESWT treatment on pain, function and size of the calcaneal spur in patients with clinical and radiological diagnosis of plantar fasciitis. A total of 112 patients aged between 18 and 95 years, were divided into 2 groups; group 1, rESWT (2.4 bar 12 hz 2000 beats), group 2 received fESWT (0.14 bar 14 hz 1000 beats) 3 times a week for 3 weeks. All patients were evaluated using the Visual Analog Scale (VAS)-pain and Foot Function Index before and after the treatment, at 4 week and 12 weeks. Calcaneal spur size was measured radiographically in the patients before and after the treatment at the 12th week follow-up. According to our records, VAS scores were found to be similar between the groups before treatment and at follow-ups (all p > .05). In both groups, a significant decrease in VAS scores was found in the follow-ups compared to before treatment (p < .001). FFI total, pain, activity and disability scores were found to be similar between the groups before treatment and at follow-up (all p > .05). In both groups, a significant decrease in Foot Function Index scores was found in the follow-ups compared to before treatment (p < .001). Both of rESWT and fESWT were effective in plantar fasciitis treatment there were no significant difference between 2 modalities in long term.

2.
J Infect Dev Ctries ; 18(6): 870-879, 2024 Jun 30.
Article in English | MEDLINE | ID: mdl-38990997

ABSTRACT

INTRODUCTION: Although few studies have emphasized the preventive and therapeutic efficacy of dietary supplements in COVID-19, their efficacy in the postinfection period has not been focused. The aim of the current study was to examine the effects of therapeutic use of dietary supplements during COVID-19 treatment on post-COVID academic motivation in college students METHODOLOGY: The study was conducted with 1584 college students studying at Karamanoglu Mehmetbey University. Three-day food consumption was recorded and anthropometric measurements (height and body weight) were taken to assess nutritional status. The Academic Motivation Scale (AMS), a 28-item 7-point Likert scale consisting of three subdimensions (amotivation, intrinsic motivation, and extrinsic motivation), was used to assess the motivational status of participants. RESULTS: The rate of participants who survived COVID-19 was 35.9% (n = 568). There was no significant difference in AMS subscores between participants who routinely used dietary supplements and those who did not. Participants who used dietary supplements preventively had higher intrinsic motivation scores than those who did not. Lastly, all AMS subscores of COVID-19 survivors who used dietary supplements therapeutically during treatment were found to be more favorable than those who did not. However, there was no significant difference in AMS subscores between the types of dietary supplements most frequently used therapeutically. CONCLUSIONS: The finding of higher post-COVID academic motivation in COVID-19 survivors who used dietary supplements as an adjunct to treatment will make an important contribution to the literature. However, longitudinal intervention studies examining the effectiveness of specific dietary supplements in COVID-19 will undoubtedly provide more valuable results.


Subject(s)
COVID-19 , Dietary Supplements , Motivation , Students , Humans , COVID-19/psychology , Students/psychology , Male , Female , Young Adult , Universities , Adult , SARS-CoV-2 , Adolescent , Nutritional Status
3.
Turk J Phys Med Rehabil ; 70(2): 171-179, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38948643

ABSTRACT

Objectives: The study aimed to analyze the relationship between serum adiponectin concentration, Mediterranean diet (MD) adherence, and Dietary Approaches to Stop Hypertension (DASH) diet adherence in patients with spinal cord injury (SCI). Patients and methods: Thirty-three SCI patients (21 males, 12 females; median age: 33 years; range, 18 to 65 years) and 33 age-, sex-, and body mass index-matched healthy controls (21 males, 12 females; median age: 33 years; range, 18 to 64 years) were included in this cross-sectional study between March 2021 and March 2022. Serum adiponectin concentrations of all participants were measured. Body weight, height, and neck, hip, waist, and mid-upper arm circumferences were measured. Twenty-four-hour dietary records were obtained by the researchers for evaluation of the nutritional status. The DASH diet score and MD score were measured for each participant. Results: Most of the cases of SCI were due to motor vehicle collisions (n=12, 36.4%) and complete paraplegic. Mid-upper arm circumference, waist circumference, hip circumference, and neck circumference of the patient group were significantly higher than the control group (p=0.020, p=0.002, p=0.042, and p<0.001, respectively). Mediterranean diet scores and DASH diet scores of the patient group were significantly higher than the control group (p<0.001 and p=0.031, respectively). Serum adiponectin concentration of patients was significantly higher than the control group (p=0.049). No correlation was detected between adiponectin concentration, MD score, and DASH diet score in both groups. Conclusion: Although correlation analysis in the current research did not show significant relation between nutrition and adiponectin concentrations, nutrition of patients with SCI, as demonstrated by higher adherence to MD and DASH, may have provided positive effects on adiponectin concentrations. Future studies focused on the effect of a healthy diet intervention on serum adiponectin concentration is warranted.

4.
J Health Popul Nutr ; 43(1): 101, 2024 Jul 04.
Article in English | MEDLINE | ID: mdl-38965642

ABSTRACT

This study aimed to examine dietary antioxidant and serum antioxidant capacity in patients with knee osteoarthritis (OA). This case-control study consisted of 47 patients with OA (case group) and 30 healthy subjects (control group). The control and case group were matched age, gender, and body mass index (p > 0.05). A food frequency questionnaire was administered to participants, and dietary total antioxidant capacity (DTAC) was estimated using the ferric reducing antioxidant power method (FRAP). Participants' serum total antioxidant capacity (TAC) and total oxidant capacity (TOC) measurements were performed, and the oxidative stress index (OSI) was calculated. DTAC of case group was found to be lower than the control group (p < 0.05). The daily consumption of red meat and butter of the individuals in the case group was higher than that of the control group, and their fish consumption, dietary vitamin A and carotene intakes were found to be lower (p < 0.05). In addition, OA patients have TAC and OSI was also found to be significantly higher than in control group (p = 0.001 and p < 0.001). Since low dietary total antioxidant capacity and high serum total oxidant capacity, individuals with OA should pay more attention to their diet to increase serum antioxidant status.


Subject(s)
Antioxidants , Diet , Osteoarthritis, Knee , Oxidative Stress , Humans , Case-Control Studies , Female , Male , Antioxidants/metabolism , Antioxidants/analysis , Middle Aged , Osteoarthritis, Knee/blood , Aged , Body Mass Index
5.
Eur J Pharmacol ; 977: 176706, 2024 Aug 15.
Article in English | MEDLINE | ID: mdl-38843946

ABSTRACT

Astaxanthin is a potent lipid-soluble carotenoid produced by several different freshwater and marine microorganisms, including microalgae, bacteria, fungi, and yeast. The proven therapeutic effects of astaxanthin against different diseases have made this carotenoid popular in the nutraceutical market and among consumers. Recently, astaxanthin is also receiving attention for its effects in the co-adjuvant treatment or prevention of neurological pathologies. In this systematic review, studies evaluating the efficacy of astaxanthin against different neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, cerebrovascular diseases, and spinal cord injury are analyzed. Based on the current literature, astaxanthin shows potential biological activity in both in vitro and in vivo models. In addition, its preventive and therapeutic activities against the above-mentioned diseases have been emphasized in studies with different experimental designs. In contrast, none of the 59 studies reviewed reported any safety concerns or adverse health effects as a result of astaxanthin supplementation. The preventive or therapeutic role of astaxanthin may vary depending on the dosage and route of administration. Although there is a consensus in the literature regarding its effectiveness against the specified diseases, it is important to determine the safe intake levels of synthetic and natural forms and to determine the most effective forms for oral intake.


Subject(s)
Antioxidants , Neurodegenerative Diseases , Neuroprotective Agents , Xanthophylls , Xanthophylls/pharmacology , Xanthophylls/therapeutic use , Neuroprotective Agents/pharmacology , Neuroprotective Agents/therapeutic use , Humans , Animals , Neurodegenerative Diseases/drug therapy , Neurodegenerative Diseases/prevention & control , Antioxidants/pharmacology , Antioxidants/therapeutic use , Aquatic Organisms
6.
Neuroscience ; 551: 290-298, 2024 Jul 23.
Article in English | MEDLINE | ID: mdl-38851379

ABSTRACT

High-intensity interval training (HIIT) is a time-efficient, safe, and feasible exercise type that can be utilized across different ages and health status. This randomized cross-over study aimed to investigate the effect of acute HIIT on cortical excitability, M1-related cognitive functions, cognition-related myokines, brain-derived neurotrophic factor (BDNF), and Cathepsin B (CTSB). Twenty-three sedentary young adults (mean age: 22.78 years ± 2.87; 14 female) participated in a cross-over design involving two sessions: either 23 min of HIIT or seated rest. Before and after the sessions, cortical excitability was measured using transcranial magnetic stimulation, and M1-related cognitive functions were assessed by the n-back test and mental rotation test. Serum levels of BDNF and CTSB were assessed using the ELISA method before and after the HIIT intervention. We demonstrated that HIIT improved mental rotation and working memory, and increased serum levels of BDNF and CTSB, whereas cortical excitability did not change. Our findings provide evidence that one session of HIIT is effective on M1-related cognitive functions and cognition-related myokines. Future research is warranted to determine whether such findings are transferable to different populations, such as cognitively at-risk children, adults, and older adults, and to prescribe effective exercise programs.


Subject(s)
Brain-Derived Neurotrophic Factor , Cathepsin B , Cognition , Cortical Excitability , Cross-Over Studies , High-Intensity Interval Training , Transcranial Magnetic Stimulation , Humans , Female , Male , High-Intensity Interval Training/methods , Brain-Derived Neurotrophic Factor/blood , Cognition/physiology , Young Adult , Cortical Excitability/physiology , Cathepsin B/blood , Cathepsin B/metabolism , Adult , Motor Cortex/physiology , Memory, Short-Term/physiology , Evoked Potentials, Motor/physiology , Myokines
7.
Pain Pract ; 24(6): 839-844, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38459756

ABSTRACT

PURPOSE: The aim was to evaluate the efficacy of ultrasound-guided erector spinae plane (ESP) block and compare with the conventional physical therapy in chronic low back pain (LBP). MATERIALS AND METHODS: This prospective case-controlled study included patients with chronic LBP. Their clinical and demographic data were obtained, and they were divided into two groups for conventional physical therapy and ESP blocks. Prior to treatment, on the first day, the second week, and the third month, the Oswestry Disability Index (ODI) and visual analog scale (VAS) pain score were evaluated. RESULTS: The study included 43 patients, 21 in the ESP block group and 22 in the conventional physical therapy group. The VAS in movement was higher in the ESP block group at baseline (p = 0.047). On the first day after the treatments, the ESP block group showed lower resting (p < 0.001) and movement (p = 0.001) VAS values than the conventional physical therapy group. At the end of 3 months, both groups had improved VAS and ODI scores (all p < 0.001). CONCLUSION: US-guided ESP block might be considered a successful, safe, and technically simple alternative treatment in patients with chronic LBP to control pain and reduce the cost of physical therapy and lost workdays.


Subject(s)
Chronic Pain , Low Back Pain , Nerve Block , Ultrasonography, Interventional , Humans , Male , Female , Nerve Block/methods , Case-Control Studies , Low Back Pain/therapy , Middle Aged , Prospective Studies , Adult , Ultrasonography, Interventional/methods , Chronic Pain/therapy , Zygapophyseal Joint , Pain Measurement/methods , Paraspinal Muscles/diagnostic imaging , Treatment Outcome , Physical Therapy Modalities , Lumbar Vertebrae
8.
Dysphagia ; 39(2): 241-254, 2024 Apr.
Article in English | MEDLINE | ID: mdl-37542552

ABSTRACT

There is no study about all aspects of oropharyngoesophageal (OPE) dysphagia from diagnosis to follow-up in a multidisciplinary manner in the world. In order to close this gap, we aimed to create a recommendation study that can be used in clinical practice, addressing all aspects of dysphagia in the ICU in detail with the opinion of experienced multidisciplinary experts. This recommendation paper was generated by a multidisciplinary team, using the seven-step process and a three-modified Delphi round via e-mail. Firstly, 15 open-ended questions were created, and then detailed recommendations including general principles, management, diagnosis, rehabilitation, and follow-up were created with the answers from these questions, Each recommendation item was voted on by the experts as overall consensus (strong recommendation), approaching consensus (weak recommendation), and divergent consensus (not recommended).In the first Delphi round, a questionnaire consisting of 413 items evaluated with a scale of 0-10 was prepared from the opinions and suggestions given to 15 open-ended questions. In the second Delphi round, 55.4% were accepted and revised suggestions were created. At the end of the third Delphi round, the revised suggestion form was approved again and the final proposals containing 133 items were created. This study includes comprehensive and detailed recommendations, including a broad perspective from diagnosis to treatment and follow-up, as detailed as possible, for management of dysphagia in patients with both oropharyngeal- and esophageal-dysphagia in ICU.


Subject(s)
Deglutition Disorders , Humans , Delphi Technique , Deglutition Disorders/diagnosis , Deglutition Disorders/therapy , Turkey , Surveys and Questionnaires , Intensive Care Units
9.
Nutr Neurosci ; : 1-17, 2023 Aug 03.
Article in English | MEDLINE | ID: mdl-37534957

ABSTRACT

Objectives: Autism is a devastating neurodevelopmental disorder and recent studies showed that omega-3 or astaxanthin might reduce autistic symptoms due to their anti-inflammatory properties. Therefore, we investigated the effects of omega-3 and astaxanthin on the VPA-induced autism model of rats.Material and Methods: Female Wistar albino pups (n = 40) were grouped as control, autistic, astaxanthin (2 mg/kg), omega-3 (200 mg/kg), and astaxanthin (2 mg/kg)+omega-3 (200 mg/kg). All groups except the control were prenatally exposed to VPA. Astaxanthin and omega-3 were orally administered from the postnatal day 41 to 68 and behavioral tests were performed between day 69 and 73. The rats were decapitated 24 h after the behavioral tests and hippocampal and prefrontal cytokines and 5-HT levels were analyzed by ELISA.Results: VPA rats have increased grooming behavior while decreased sociability (SI), social preference index (SPI), discrimination index (DI), and prepulse inhibition (PPI) compared to control. Additionally, IL-1ß, IL-6, TNF-α, and IFN-γ levels increased while IL-10 and 5-HT levels decreased in both brain regions. Astaxanthin treatment raised SI, SPI, DI, PPI, and prefrontal IL-10 levels. It also raised 5-HT levels and decreased IL-6 levels in both brain regions. Omega-3 and astaxanthin + omega-3 increased the SI, SPI, DI, and PPI and decreased grooming behavior. Moreover, they increased IL-10 and 5-HT levels whereas decreased IL-1ß, IL-6, TNF-α, IFN-γ levels in both brain regions.Conclusions: Our results showed that VPA administration mimicked the behavioral and molecular changes of autism in rats. Single and combined administration of astaxanthin and omega-3 improved the autistic-like behavioral and molecular changes in the VPA model of rats.

12.
Physiol Behav ; 256: 113961, 2022 11 01.
Article in English | MEDLINE | ID: mdl-36100109

ABSTRACT

Autism spectrum disorders are neuropsychiatric conditions characterized by social interaction and communication disorders and repetitive stereotypical behaviors. These disorders are also accompanied by an inflammatory status. Bidirectional communication between microbiome, gut, and brain has been discovered as a major mechanism influencing core symptoms and biomarkers of autism. Therefore, the modulation of the gut microbiota in autism has recently attracted interest. In this study, probiotic- and prebiotic-mediated modulation of the gut microbiota was compared in terms of different symptoms and findings in an experimental autism model. Valproic acid (VPA) (500 mg/kg) was administered to Wistar rats (on prenatal day 12.5) to induce autistic-like behaviors. Based on the supply of probiotics and prebiotics, animals were grouped as control (saline), autistic-like (prenatal VPA), probiotic (prenatal VPA + 22.5 × 109 cfu/day probiotic), prebiotic (prenatal VPA + 100 mg/day prebiotic), and combined treatment (prenatal VPA + 22.5 × 109 cfu/day probiotic + 100 mg/day prebiotic). After the treatment process, behavioral tests (social behaviors, anxiety, stereotypical behavior, sensorimotor gating, and behavioral despair) and biochemical analyses (serum and brain tissue) were conducted, and the quantities of some phyla and genera were determined in stool samples. Significant positive effects of probiotic and combined treatments were observed on the sociability, social interaction, and anxiety parameters. In addition, all three treatments had positive effects on stereotypical behavior. However, the treatments did not affect sensorimotor gating deficits and behavioral despair. Further, probiotic treatment reversed the VPA-induced increase and decrease in serum IL-6 and IL-10 levels, respectively. Combined treatment also significantly increased the IL-10 levels. Prenatal VPA exposure decreased 5-hydroxytryptamine (5-HT) levels in the prefrontal cortex of the brain; however, combined treatment reversed this decrease. Prenatal VPA exposure also caused a decrease in Bacteroidetes/Firmicutes ratio in the gut microbiota, while the probiotic treatment significantly increased this ratio. These findings indicate that probiotic- and prebiotic-mediated microbial modulation may represent a new therapeutic approach to alleviate autistic-like symptoms.


Subject(s)
Autism Spectrum Disorder , Autistic Disorder , Prenatal Exposure Delayed Effects , Probiotics , Animals , Autism Spectrum Disorder/chemically induced , Autism Spectrum Disorder/drug therapy , Autistic Disorder/psychology , Disease Models, Animal , Dysbiosis , Female , Humans , Interleukin-10 , Interleukin-6 , Prebiotics , Pregnancy , Prenatal Exposure Delayed Effects/chemically induced , Probiotics/therapeutic use , Rats , Rats, Wistar , Rodentia , Serotonin , Valproic Acid/adverse effects , Valproic Acid/therapeutic use
13.
Top Stroke Rehabil ; 29(4): 272-279, 2022 05.
Article in English | MEDLINE | ID: mdl-34060434

ABSTRACT

BACKGROUND: The Aphasia Rapid Test (ART) is a short bedside aphasia screening test developed originally in French for use with post-stroke patients in the acute phase of recovery. OBJECTIVES: The purpose of this study was to assess the inter-rater reliability of the Turkish version of the ART in stroke patients (ICTRP ID: NCT04386837). METHODS: The French ART was translated into Turkish. Inter-rater reliability was assessed in 30 post-stroke patients with aphasia by two independent speech-language pathologists blind to each other's ratings. RESULTS: 30 patients (18 men, 12 women; mean age 64.43 ± 16.60 years) were included within 10 days of stroke onset, as assessed by clinical examination and confirmed by CT and/or MRI. The mean (± SD) ART value was 16.26 (± 8.05) for rater 1 and 16.43 (±8.14) for rater 2. The inter-rater concordance coefficient was 0.997 (95% CI 0.994-0.999; p < .001). CONCLUSIONS: Findings indicate that the Turkish version of the original ART was successfully administered in Turkish-speaking patients.


Subject(s)
Aphasia , Stroke , Aged , Aged, 80 and over , Aphasia/diagnosis , Aphasia/etiology , Female , Humans , Language , Male , Middle Aged , Reproducibility of Results , Stroke/complications , Translating
14.
Rheumatol Int ; 41(12): 2167-2175, 2021 12.
Article in English | MEDLINE | ID: mdl-34580754

ABSTRACT

This study aimed to detect patients' characteristics who suffered severe and critical COVID-19 pneumonia admitted to the post-acute COVID-19 rehabilitation clinic in Ankara City Hospital, Physical Medicine and Rehabilitation Hospital and to share our experiences and outcomes of rehabilitation programmes applied. This study was designed as a single-centre, retrospective, observational study. Severe and critical COVID-19 patients, admitted to the post-acute COVID-19 rehabilitation clinic, were included in patient-based rehabilitation programmes, targeting neuromuscular and respiratory recovery. Functional status, oxygen (O2) requirement and daily living activities were assessed before and after rehabilitation. Eighty-five patients, of which 74% were male, were analysed, with the mean age of 58.27 ± 11.13 and mean body mass index of 25.29 ± 4.81 kg/m2. The most prevalent comorbidities were hypertension (49.4%) and diabetes mellitus (34.1%). Of the 85 patients, 84 received antiviral drugs, 81 low-molecular-weight heparin, 71 corticosteroids, 11 anakinra, 4 tocilizumab, 16 intravenous immunoglobulin and 6 plasmapheresis. 78.8% of the patients were admitted to the intensive care unit, with a mean length of stay of 19.41 ± 18.99 days, while those who needed O2 support with mechanic ventilation was 36.1%. Neurological complications, including Guillain-Barré syndrome, critical illness-related myopathy/neuropathy, cerebrovascular disease and steroid myopathy, were observed in 39 patients. On initial functional statuses, 55.3% were bedridden, 22.4% in wheelchair level and 20% mobilised with O2 support. After rehabilitation, these ratios were 2.4%, 4.7% and 8.2%, respectively. During admission, 71 (83.5%) patients required O2 support, but decreased to 7 (8.2%) post-rehabilitation. Barthel Index improved statistically from 44.82 ± 27.31 to 88.47 ± 17.56. Patient-based modulated rehabilitation programmes are highly effective in severe and critical COVID-19 complications, providing satisfactory well-being in daily living activities.


Subject(s)
COVID-19/rehabilitation , Exercise Therapy/methods , Rehabilitation Centers/organization & administration , Aged , COVID-19/epidemiology , Comorbidity , Female , Humans , Male , Middle Aged , Pandemics , Rehabilitation Centers/statistics & numerical data , Retrospective Studies , SARS-CoV-2 , Treatment Outcome , Turkey/epidemiology
15.
J Stroke Cerebrovasc Dis ; 30(7): 105795, 2021 Jul.
Article in English | MEDLINE | ID: mdl-33887662

ABSTRACT

OBJECTIVE: This randomized controlled study examined the effect of continuous theta burst stimulation (cTBS) and low frequency repetitive transcranial magnetic stimulation (rTMS) on upper extremity spasticity and functional recovery in chronic ischemic stroke patients. MATERIALS AND METHODS: Twenty chronic ischemic stroke patients were randomized into three groups as real rTMS group (n = 7), real cTBS group (n = 7) and sham cTBS group (n = 6), in which real rTMS with physical therapy (PT), real cTBS with PT and sham cTBS with PT were applied in 10 sessions, respectively. The evaluation parameters were assessed at pre-treatment, post-treatment and follow up at 4 weeks. RESULTS: Ten sessions of real rTMS or real cTBS combined with PT were found beneficial in motor functional recovery and daily living activities both at post-treatment and follow up at 4 weeks (p Ë‚ 0.05). In the sham cTBS group, functional improvement was not significant (p > 0.05). In addition, in the real rTMS group, elbow flexor, pronator, wrist flexor and finger flexor spasticity were significantly decreased; in the real cTBS group, significant decrease was observed in the elbow flexor and wrist flexor spasticity (p Ë‚ 0.05). In comparison with sham cTBS group, only in the real cTBS group, significant improvement was observed in the level of wrist flexor spasticity at follow up at 4 weeks (p Ë‚ 0.017). CONCLUSIONS: In this study, it was observed that real cTBS or real rTMS combined with PT provided improvement on upper extremity motor functions and daily living activities in chronic ischemic stroke patients, but improvement in spasticity was limited.


Subject(s)
Brain/physiopathology , Ischemic Stroke/therapy , Motor Activity , Theta Rhythm , Transcranial Magnetic Stimulation , Upper Extremity/innervation , Aged , Chronic Disease , Combined Modality Therapy , Disability Evaluation , Double-Blind Method , Female , Functional Status , Humans , Ischemic Stroke/diagnosis , Ischemic Stroke/physiopathology , Male , Middle Aged , Physical Therapy Modalities , Recovery of Function , Time Factors , Transcranial Magnetic Stimulation/adverse effects , Treatment Outcome , Turkey
16.
Turk J Phys Med Rehabil ; 65(1): 67-73, 2019 Mar.
Article in English | MEDLINE | ID: mdl-31453545

ABSTRACT

OBJECTIVES: This study aims to investigate the effect of rehabilitation on functional level of traumatic brain injury (TBI) patients and to examine the associated factors on functional gain in this patient population. PATIENTS AND METHODS: Between October 2010 and November 2015, a total of 71 patients (63 males, 8 females; mean age 26.6±8.1 years; range, 18 to 56 years) who were admitted to our rehabilitation clinic with moderate-to-severe TBI were retrospectively analyzed. Functional recovery was assessed using the Functional Independence Measure (FIM) and Functional Ambulation Classification (FAC) scales. The patients were divided into two groups according to time from TBI to the initiation of rehabilitation: early (<6 months) and late (≥6 months). Possible predictive factors associated with FIM gain were evaluated. RESULTS: There was a significant improvement in the FIM scores from admission to discharge (p<0.001). There was a statistically significant difference in the FIM gain and FIM efficiency between the patient groups according to the initiation of rehabilitation (p<0.001). The FAC scores increased from admission to discharge, showing statistical significance (p<0.001). Duration of rehabilitation, early rehabilitation, heterotopic ossification, and deep venous thrombosis were found to be significant factors associated with FIM gain (p<0.001). CONCLUSION: Our study results suggest that rehabilitation is effective for functional gain, particularly in the early period in patients with moderate- to-severe TBI and duration of rehabilitation, early rehabilitation, heterotopic ossification, and deep venous thrombosis are also predictors of functional improvement.

17.
Turk J Phys Med Rehabil ; 65(2): 177-183, 2019 Jun.
Article in English | MEDLINE | ID: mdl-31453559

ABSTRACT

OBJECTIVES: This study aims to identify the most accurate method or ultrasonographic measurement for the diagnosis of carpal tunnel syndrome (CTS). PATIENTS AND METHODS: Between October 2010 and April 2011, a total of 160 hands of 87 patients (4 males, 83 females; mean age 54.5 years; range, 26 to 84 years) with clinically and electrodiagnostically proven CTS and 80 hands of 40 controls (3 males, 37 females; mean age 53.7 years; range, 32 to 77 years) were evaluated by sonographic examination. The diameters and cross-sectional areas (CSA) of the median nerve and longitudinal diameters of the median nerve were measured at the inlet, proximal carpal tunnel, and outlet of the carpal tunnel. Volar bulging and thickness of the retinaculum were also measured. RESULTS: The most optimal combination for the diagnosis of CTS was proximal CSA, volar bulging, and the proximal transverse diameter. The combination of proximal CSA with volar bulging increased the sensitivity and specificity of sonographic measurements. CONCLUSION: Based on our study results, ultrasonography can be used as a practical modality to distinguish CTS patients from asymptomatic controls.

18.
Pak J Med Sci ; 35(4): 974-980, 2019.
Article in English | MEDLINE | ID: mdl-31372127

ABSTRACT

OBJECTIVE: To evaluate the natural history of lumbar extruded disc with conservative treatment on MRI and to assess relation between the radiologic changes and clinical outcome. METHODS: This prospective observational study was conducted at University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital between May 2015-June 2018. It included consecutive patients who were diagnosed as having lumbar symptomatic extruded disc as shown in MRI. After an average period of 17.0±7.2 months, repeat MRI was taken in 40 patients who received only conservative care during follow-up. Changes in the volume of herniated disc was measured. The patients were assigned into 3 groups as follow: (1) non-regression, (2) partial-regression, and (3) complete resolution. Numeric Rating Scale (NRS) pain score, the Oswestry Low Back Pain Disability Index (ODI) and muscle weakness were evaluated. RESULTS: Based on disc volume of the T2-weighted MR images; four patients (10%) did not show any regression, six patients (15%) had a partial regression, and 30 patients (75%) had a complete resolution. Patients with complete resolution showed a significant improvement in the NRS pain score and the ODI score (p<0,001) over time. In patients with partial regression, only the ODI score improved significantly (p=0,043). Non-regression group did not show any improvement in any clinical outcome measure (p>0,05). Changes in the NRS scores over time were significantly higher in complete resolution group compared to non-regression group (p=0.016). CONCLUSION: The majority of the patients with extruded lumbar disc herniation might have reduction in size of herniated disc in the long run along with improvement in symptoms and function with conservative care.

19.
Exp Gerontol ; 120: 15-20, 2019 06.
Article in English | MEDLINE | ID: mdl-30822485

ABSTRACT

INTRODUCTION: There is evidence that nutritional status is one of the major factors affecting quality of life. Low quality of life is an important reason that reflects the risk of malnutrition as well as dependency and frailty. OBJECTIVE: The present study aimed to examine nutritional risk factors and sociodemographic features affecting health-related quality of life in home care patients. MATERIALS AND METHODS: The data of 209 adult or elderly eligible subjects were evaluated in the study. A general questionnaire including sociodemographic and nutritional characteristics, 'Mini Nutritional Assessment (MNA)', 'Short Form-36 (SF-36) health related life quality scale' and '24-hour dietary recall' were applied with face-to-face interview. Anthropometric measurements were performed using standard measurement protocols and, height and weight measurements of bedridden patients were calculated by equality formulas. RESULTS: While 52.6% of patients were malnourished according to the MNA, only 7.7% were underweight according to the body mass index (BMI). The SF-36 summary component scores (physical and mental component summary scale scores) of malnourished patients were significantly lower than patients at risk of malnutrition or normal (p < 0.05). There were significant positive correlations between SF-36 physical component summary scale scores were significantly correlated with MNA scores (r = 0.517), BMI (r = 0.140) and daily dietary macronutrient intake (energy (r = 0.328), protein (r = 0.165), carbohydrate (r = 0.305), fat (r = 0.275) and fiber (r = 0.268)) (p < 0.05). Besides there were significant positive correlation between SF-36 mental component summary scale scores and MNA scores (r = 0.719), BMI (r = 0.318), daily dietary macronutrient intake (energy (r = 0.388), protein (r = 0.204), carbohydrate (r = 0.335), fat (r = 0.365) and fiber (r = 0.349)) (p < 0.05). It was also determined that MNA had the greatest positive effect and 'having a caregiver' had the greatest negative effect on the physical and mental component summary scale scores. CONCLUSION: Periodic nutritional screening of home care patients is important and necessary for early nutritional intervention and thus prevention of morbidity and mortality.


Subject(s)
Home Care Services , Nutritional Status , Quality of Life , Adult , Aged , Aged, 80 and over , Body Mass Index , Cross-Sectional Studies , Female , Humans , Male , Malnutrition/epidemiology , Middle Aged , Nutrition Assessment
20.
Iran J Public Health ; 48(12): 2232-2239, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31993392

ABSTRACT

BACKGROUND: We aimed to investigate the cystic echinococcosis (CE) epidemiology in Karaman Province from 2010 to 2017 using data from the provincial state hospital. METHODS: Overall, 482 cases were determined from Karaman State Hospital, Karaman Province, Turkey from 2010 to 2017. Records were investigated in terms of year, gender, age, cyst location, rural and urban households and duration of hospital stay. RESULTS: The CE incidence was 22.40 per 100 000 people after final diagnosis with focused abdominal ultrasound. Totally, 482 people including 166 (34.4%) male and 316 (65.6%) female were with CE. The mean age of patients was 50.3±17.48 yr. More CE cases were reported in the age group of 51-60 yr than in the other age groups. CE was mostly seen in liver (470, 97.5%). Moreover, 28.4% of patients were resided in rural areas. The observed frequencies of demographic features of female gender, infected liver, residence in provincial centers, referral to general surgery policlinic and no hospitalization were significantly higher than expected frequencies (P<0.05). Sixty (12.4%) patients with CE had been hospitalized. There was a statistically significant positive relationship between age of hospitalized patients and duration of hospitalization (P<0.05). Of the patients 73.2% were admitted to general surgery. CONCLUSION: CE is of great importance to public health considerations in the Karaman Province and we advocate the implementation of eradication programs to decrease the CE cases number.

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