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1.
Chirurgia (Bucur) ; 107(3): 332-6, 2012.
Article in Romanian | MEDLINE | ID: mdl-22844831

ABSTRACT

UNLABELLED: The aim of this study was to describe a single institution's experience with transanal endoscopic microsurgery (TEMS) in patients with benign and malignant rectal tumors. MATERIAL AND METHOD: This was a prospective descriptive survey. Between January 2006 and January 2010, 14 patients underwent transanal endoscopic microsurgery excision of benign (8) or malignant (6) rectal tumors, located 4 to 15 cm from the dentate line. Median age was 59.7 years and the mean follow up was 29 months. RESULTS: The average tumor size was 3.4 cm, median operating time was 40 min. Median length of hospital stay was 4.35 days. During the follow-up period, benign tumor recurrence was observed in one patient (7.14%), managed by repeated TEMS. Histologic staging of malignant tumors was T1 (2) and T2 (4). In two patients with inadequate resection margins open radical surgery was performed. One had recurrent disease, which was managed by radical surgery. No cancer-related deaths were observed during the follow-up period. There was no operative mortality. No major postoperative complications were recorded. Anal incontinence persisted for 3 weeks in one patient. CONCLUSION: Transanal endoscopic microsurgery excision is a safe and precise technique and should become a procedure of choice for benign rectal tumors and selected early malignant neoplasms.


Subject(s)
Anal Canal , Natural Orifice Endoscopic Surgery , Neoplasm Recurrence, Local/surgery , Rectal Neoplasms/surgery , Adult , Aged , Aged, 80 and over , Anus Neoplasms/surgery , Female , Follow-Up Studies , Humans , Length of Stay , Male , Microsurgery , Middle Aged , Natural Orifice Endoscopic Surgery/adverse effects , Natural Orifice Endoscopic Surgery/methods , Neoplasm Recurrence, Local/pathology , Neoplasm Staging , Prospective Studies , Rectal Neoplasms/pathology , Time Factors , Treatment Outcome
2.
Chirurgia (Bucur) ; 107(1): 52-4, 2012.
Article in English | MEDLINE | ID: mdl-22480116

ABSTRACT

UNLABELLED: Six gastrojejunocolic fistulae were recorded at our service between 1995-2005. All the fistulae occurred in men who had gastric resection performed for duodenal ulcer. METHOD: Diarrhea, weight loss, postprandial pain and fecal breath were the clinical findings present in descending frequency. Preoperative diagnosis was possible in 5 patients by endoscopy and barium contrast studies. In five patients the option was a one-stage procedure with revision gastrectomy and segmental resection of the transverse colon. In one case simple dismantling of the fistula was performed. RESULTS: Although in two patients anastomotic leakage developed no mortality was recorded.


Subject(s)
Colonic Diseases/etiology , Duodenal Ulcer/surgery , Gastrectomy/adverse effects , Gastric Fistula/etiology , Intestinal Fistula/etiology , Jejunal Diseases/etiology , Adult , Aged , Colectomy/methods , Colonic Diseases/surgery , Gastric Fistula/surgery , Humans , Intestinal Fistula/surgery , Jejunal Diseases/surgery , Male , Middle Aged , Reoperation , Retrospective Studies , Treatment Outcome
3.
Chirurgia (Bucur) ; 106(5): 661-4, 2011.
Article in Romanian | MEDLINE | ID: mdl-22165068

ABSTRACT

The frequency of upper gastrointestinal hemorrhage as a postoperative complication of cephalic duodenopancreatectomy remained constant for decades despite the overall decrease in the incidence of mortality occuring after cephalic duodeno-pancreatomy. It is the second most common complication after anastomotic fistulas, but more frequently fatal, especially when the pancreas is anastomosed with the stomach. The case presented here is of a patient of 55 years age, diagnosed in our clinic with vaterian ampuloma for which was performed cephalic duodenopancreatectomy and gastrointestinal and hepatobiliary continuity was restored by performing terminolateral pancreato-gastric anastomosis, termino-lateral hepato-jejunal anatomosis and termino-lateral gastro-jejunal anastomosis on a jejunal loop ascended transmezocolic. Postoperative evolution of the patient was marked by appearance of two episodes of upper gastrointestinal hemorrhage, the first being solved by relaparotomy and the second benefiting from the contribution of an endoscopic intervention. From this case, we analyze risk factors for upper gastrointestinal hemorrhage appearing after cephalic duodeno-pancreatectomy and its therapeutic modalities, starting from the fact that currently there is no consensus among experts on this matter.


Subject(s)
Gastrointestinal Hemorrhage/etiology , Pancreaticoduodenectomy/adverse effects , Postoperative Hemorrhage/etiology , Anastomosis, Surgical/adverse effects , Digestive System Surgical Procedures/adverse effects , Humans , Male , Middle Aged , Reoperation , Treatment Outcome
4.
Chirurgia (Bucur) ; 106(4): 479-84, 2011.
Article in Romanian | MEDLINE | ID: mdl-21991873

ABSTRACT

INTRODUCTION: Despite significant progress, the management of acute colonic obstruction still remains a challenging problem. The purpose of this study was represented by the evaluation of the clinical results of different techniques of resection for malignant colorectal (primary or staged) obstruction. METHODS: We performed a non-randomized clinical study. 590 patients with malignant colorectal occlusion who underwent surgery treatment an 3rd Surgical Clinic Cluj-Napoca between 1996-2005 were included. RESULTS: Patients with large bowel obstruction underwent one-stage primary resection with anastomosis in 267 cases or staged interventions in 323 cases. The groups were matched in: age, sex, comorbidities, tumor staging, serum preoperative levels of hemoglobin and proteins. The analysis of mortality and morbidity following surgical treatment for large bowel obstruction returned no significant difference among the two groups (p > 0.05). Moreover, the presented results showed a higher incidence of mortality (11.45% vs 9.33 %), morbidity (25.38% vs 14.6%) and increased hospitalization period (p = 0.029) among the patients that undergone seriate resections. CONCLUSIONS: One stage primary resections with anastomosis of the large bowel can be performed safely in case of emergency whenever patient comorbidities and local conditions do not stand as major restrictions.


Subject(s)
Colectomy , Colonic Neoplasms/surgery , Intestinal Obstruction/surgery , Rectal Neoplasms/surgery , Aged , Aged, 80 and over , Colectomy/methods , Colonic Neoplasms/complications , Colonic Neoplasms/mortality , Colonic Neoplasms/pathology , Female , Humans , Intestinal Obstruction/etiology , Intestinal Obstruction/mortality , Length of Stay , Male , Middle Aged , Neoplasm Staging , Rectal Neoplasms/complications , Rectal Neoplasms/mortality , Rectal Neoplasms/pathology , Retrospective Studies , Risk Factors , Survival Analysis , Treatment Outcome
5.
Chirurgia (Bucur) ; 106(1): 33-6, 2011.
Article in Romanian | MEDLINE | ID: mdl-21523957

ABSTRACT

INTRODUCTION: The radical treatment of the gastric cancer consist in large gastric resections and lymphadenectomy. Resection line involvement at microscopic histopathological examination (R1) could change prognostic unfavorable. MATERIAL AND METHODS: They were 135 patients with gastric cancer operated between 2006-2007, with radical gastric resections and lymphadenectomy. In 3 patients with early gastric cancer and 23 patients with different stages of cancers, histopathological examination showed resection line involvement. From this study were eliminated the patients with stage IV cancers in whom resections were palliative. RESULTS: Incidence of positive resection line involvement was 19,25%. 88,46% of the tumors were staged pT2 and pT3 and the majority was poorly differentiated or undifferentiated (G3 and G4). Lymphatic involvement (pN1 or pN2) was demonstrated in 18 (69,23%0 patients with R1. Perioperative complications were encountered in 15,38% of this patients, with 7,69% mortality. CONCLUSIONS: Presence of tumoral tissue at resection line level could decrease survival in this patients. Therapeutic protocol in patients with resection line involvement (re-laparotomy with re-resection or surveillance) must be establish in accordance with several factors: T and N category, risks of another surgical interventions, patients acceptance.


Subject(s)
Carcinoma/surgery , Gastrectomy/adverse effects , Neoplasm Recurrence, Local/prevention & control , Neoplasm, Residual/surgery , Stomach Neoplasms/surgery , Adult , Aged , Aged, 80 and over , Carcinoma/mortality , Carcinoma/pathology , Female , Follow-Up Studies , Gastrectomy/methods , Humans , Incidence , Lymph Node Excision , Male , Middle Aged , Neoplasm Staging , Prognosis , Reoperation , Retrospective Studies , Risk Factors , Romania/epidemiology , Stomach Neoplasms/mortality , Stomach Neoplasms/pathology , Survival Rate , Treatment Outcome
6.
Chirurgia (Bucur) ; 105(3): 383-6, 2010.
Article in Romanian | MEDLINE | ID: mdl-20726306

ABSTRACT

BACKGROUND: Starting from the premise that abdominal tumours require very accurate assessment and staging, the study "DIASTAL" (laparoscopic diagnosis and staging of abdominal tumours) proposed to establish the effectiveness of laparoscopy in the diagnosis and resectability of these neoplasms. The aim of this study was to evaluate diagnostic laparoscopy for periampullary and pancreatic neoplasms. METHODS: The clinical study was based on the analysis two different groups including 27 patients in total, in whom we used also diagnostic laparoscopy as a staging method. RESULTS: The percentage of understaged patients after preoperative examinations was high in both groups range 59.09%-63.63%. Diagnostic laparoscopy reduced the number of unnecessary laparotomies. CONCLUSIONS: Diagnostic laparoscopy could lead to more accurate assessment of periampullary and pancreatic cancers, not only as a staging method but also as a minimally invasive surgical technique for palliation.


Subject(s)
Ampulla of Vater , Common Bile Duct Neoplasms/diagnosis , Laparoscopy , Pancreatic Neoplasms/diagnosis , Adult , Aged , Common Bile Duct Neoplasms/surgery , Female , Humans , Male , Middle Aged , Neoplasm Invasiveness , Neoplasm Staging , Palliative Care , Pancreatic Neoplasms/surgery , Predictive Value of Tests , Prognosis , Sensitivity and Specificity
7.
Chirurgia (Bucur) ; 104(4): 409-13, 2009.
Article in Romanian | MEDLINE | ID: mdl-19886047

ABSTRACT

UNLABELLED: Between 1990 and 2006 in the III-rd Surgical Clinic Cluj-Napoca, 366 pacients with hepatic hydatid cyst were admitted and underwent surgery; 81 (22.13%) of them, who had a cyst-biliary comunication, were retrospectively reviewed: 52 (64.2%) had an occult communications and 29 (35.8%) had a frank intrabiliary rupture. The sex ratio was M/F=46/35 with a mean age of 44.5 years and with ages between 17 and 73 years. Choledochotomy, evacuation of parasitic material and lavage of the CBP were performed in all patients with frank intrabiliary rupture. In 25 patients, partial pericystectomy and choledochoduodenostomy/T-tube drainage of CBP was performed. Internal drainage by a Roux-en-Y pericystectojejunostomy and biliodigestive anastomosis was carried out in 2 patients, while other two patients underwent external drainage of cystic cavity and T-tube drainage of CBP. 15 patients (51.7%) had postoperative external bile leaks (fistulas). Occult communications were managed by partial pericystectomy +/- narrowing of the residual cavity (capitonage with an omentum flap or invagination of the fibrosis capsule margins into the cavity) in 35 patients (67.3%) while in 10 patients (19.2%) internal drainage by a Roux-en-Y pericystectojejunostomy was carried out. Regional resection of the liver was performed in 4 cases (7.7%) and external drainage of residual cavity in 3 patients (5.7%). 13 patients (25%) had postoperative external bile leaks (fistulas). The mean postoperative hospitalisation was 20 days with the range 5-85 days. The mortality rate was 2.4% (2 patients): one died due to septicemia and MOFS and the other due to pulmonary thromboembolism. CONCLUSION: Postoperative bile leaks (fistulas) fallowing conservative surgery of ruptured hydatid hepatic cyst into the biliary tract are not rare regardless of the type of rupture (frank or occult). Although the opening of the biliary duct is sutured, the risk of biliary fistulas is not clearly corelated with this approach; in such cases internal drainage provides a good alternative with low morbidity.


Subject(s)
Bile Ducts, Intrahepatic/surgery , Echinococcosis, Hepatic/complications , Echinococcosis, Hepatic/surgery , Hepatectomy/methods , Adolescent , Adult , Aged , Bile Ducts, Intrahepatic/parasitology , Biliary Tract Diseases/parasitology , Biliary Tract Diseases/surgery , Biliary Tract Surgical Procedures/methods , Choledochostomy/methods , Drainage/methods , Echinococcosis, Hepatic/diagnosis , Female , Humans , Male , Middle Aged , Retrospective Studies , Rupture, Spontaneous , Survival Analysis , Treatment Outcome
8.
Chirurgia (Bucur) ; 104(3): 275-80, 2009.
Article in Romanian | MEDLINE | ID: mdl-19601458

ABSTRACT

UNLABELLED: The aim of this study was to evaluate the result of liver resection for benign hepatic lesion and to determine the risk factors for postoperative complication. Between January 2001 and December 2006 (6 years), a total of 50 patients with benign hepatic lesion underwent hepatic resection and were retrospectively reviewed. The sex ratio was M/F=31/19 with a mean age of 44 years (range 2-74). The diagnosis was: hydatid cyst in 24 patients (48%); hemangioma in 14 patients (28%), focal nodular hyperplasia (FNH) in 6 (12%), hepatic adenoma in 3 cases (6%), and hepatoblastoma in 3 patients (6%). Fourty patients (80%) had symptoms prior to surgery (mainly abdominal pain). The abnormalities were located in 34 cases on the left liver (II-IV Couinaud segments) and in 16 cases on the right liver (V-VIII Couinaud segments). Twenty-nine patients (58%) underwent atypical resections, 4 underwent left hemihepatectomy (8%), 16 underwent left lobectomy (32%) and 1 patient was treated by segmentectomy (2%). Median operating time was 108 minutes (range 60-220) and the median blood lost was 310 ml range (30- 1500). The morbidity rate was 18% (9 patients). Independent risk factors associated with the development of postoperative complication were intraoperative blood lost more than 1200 ml (p=0,015; OR=1,7) and the operating time more than 150 minutes (p=0,048; OR=1,09). There was no mortality. The mean postoperative hospitalization was 7,86 days with the range 3-23 days. CONCLUSION: 1. Liver resections for benign hepatic lesion performed in specialized centers are safe and efficient, with low morbidity and mortality. 2. Postoperative morbidity was related to the intraoperative blood lost more than 1200 ml and to the operating time more than 150 minutes.


Subject(s)
Hepatectomy/methods , Liver Diseases/mortality , Liver Diseases/surgery , Adolescent , Adult , Aged , Blood Loss, Surgical/mortality , Child , Child, Preschool , Feasibility Studies , Female , Hepatectomy/adverse effects , Hospitalization , Humans , Male , Middle Aged , Postoperative Hemorrhage/etiology , Postoperative Hemorrhage/mortality , Retrospective Studies , Risk Factors , Romania/epidemiology , Survival Analysis , Time Factors , Treatment Outcome
9.
Chirurgia (Bucur) ; 103(1): 45-51, 2008.
Article in Romanian | MEDLINE | ID: mdl-18459496

ABSTRACT

PURPOSE: We analyzed the clinical results of different techniques of resection for malignant colorectal (primary or staged) obstruction. METHODS: The subjects of this retrospective nonrandomized clinical study were 165 patients with malignant colorectal occlusion who underwent surgery treatment in our Department between 2002-2006. Patients with peritonitis or treated by means of permanent colostomy, palliative anastomosis, primary Hartman resection and rectal excision were excluded. RESULTS: Patients with large bowel obstruction caused by obstructive malignant colorectal lesions underwent either one-stage primary resection with anastomosis (77 patients) or staged interventions (88 patients). There were no differences in age, sex, comorbidities, tumor staging, serum preoperative levels of hemoglobin and proteins between the two groups of patients defined by the different surgical techniques. Regarding mortality and morbidity following surgical treatment for large bowel obstruction no significant difference among the two groups (p > 0.05) or the fistula rate (p = 0.435) was obtained. Moreover, results showed a higher incidence of mortality (11.8% vs 7.8%), morbidity (13.6 vs 10.4) and increased hospitalization period (p = 0.03) among the patients that undergone series resections. CONCLUSIONS: One stage primary resections with anastomosis of the large bowel can be performed safely in case of emergency whenever patient comorbidities and local conditions do not stand as major restrictions.


Subject(s)
Colectomy/methods , Colorectal Neoplasms/complications , Colorectal Neoplasms/surgery , Intestinal Obstruction/etiology , Intestinal Obstruction/surgery , Aged , Colorectal Neoplasms/mortality , Emergencies , Female , Hospital Mortality , Humans , Intestinal Obstruction/mortality , Male , Middle Aged , Retrospective Studies , Risk Factors , Romania/epidemiology , Survival Analysis , Treatment Outcome
10.
Chirurgia (Bucur) ; 103(1): 117-20, 2008.
Article in Romanian | MEDLINE | ID: mdl-18459509

ABSTRACT

The tumors of the small bowel are rare entities, whose incidence comprises ca. 1-5% of the total amount of tumors in the digestive tract. Most of the cases involve the ileum and duodenum is least involved. The most frequently encountered duodenal tumors are the Brunner's Gland Adenomas. We can encounter unique or multiple lesions, sessile or pedunculated which develop proximal to duodenal papilla and are usually less than 1 cm in diameter although 12 cm lesions have been reported. In most of the cases they remain asymptomatic and constitute incidental discoveries. Sometimes they can present complications such as obstruction, hemorrhage and malignant transformation. Diagnosis is difficult due to the lack of symptoms and is delayed by an average of 6 months from symptoms onset. Barium contrast studies and superior digestive endoscopy is performed in most of the cases to reveal the diagnosis, but other methods, such as CT or ultrasound can be useful. A case of duodenal adenoma is described; the patient was admitted suffering digestive hemorrhage, which resulted in melena, secondary anemia, and ulcerous dyspeptic syndrome.


Subject(s)
Adenoma/complications , Adenoma/diagnosis , Duodenal Neoplasms/complications , Duodenal Neoplasms/diagnosis , Gastrointestinal Hemorrhage/etiology , Adenoma/surgery , Duodenal Neoplasms/surgery , Gastrointestinal Hemorrhage/surgery , Humans , Male , Middle Aged , Treatment Outcome
11.
Chirurgia (Bucur) ; 103(2): 171-4, 2008.
Article in Romanian | MEDLINE | ID: mdl-18457094

ABSTRACT

METHOD AND MATERIAL: Between 1995 and 2005 a number of 98 antireflux laparoscopic procedures have been performed. The patients have answered to a 7 point questionnaire regarding the disappearance of specific gastro-esophageal symptoms, the necessity of medical adjuvant treatment as well as regarding the measure in which surgery brought a real subjective improvement. The average follow-up was 57 months (4.7 years). RESULTS: 43 laparoscopic patients have answered the questions. 10 patients had dysphagia, most of which had a spontaneous remission. Only 3 of those patients needed an endoscopic dilatation. Bloating was still possible for 33 of the patients. Retrosternal pain remained present for 14 patients. Intestinal transit disorders have showed up in 11 cases. Reflux persisted at a variable degree in 12 patients. Only 7 patients continue to follow a systematic drug treatment. 35 patients consider that the surgery has brought an improvement of their disease.


Subject(s)
Gastroesophageal Reflux/surgery , Laparoscopy , Deglutition Disorders/etiology , Female , Humans , Laparoscopy/adverse effects , Male , Pain/etiology , Quality of Life , Retrospective Studies , Surveys and Questionnaires , Treatment Outcome
12.
Chirurgia (Bucur) ; 103(2): 181-8, 2008.
Article in Romanian | MEDLINE | ID: mdl-18457096

ABSTRACT

The aim of this study is to assess clinico-pathological parameters and find out the correlation between them and their possible prognostic value. We made a retrospective analysis of a group of 468 patients with gastric adenocarcinoma which were operated in the 3rd Surgical Clinic--Cluj Napoca--01.01.1998-31.12.2003. The median age was 62 years. Patients in pTNM 0 stage were significantly younger than the rest of patients, with an average of 7.5 years. The male/female ratio was 1.7:1, this ratio being significantly higher in cases with proximal gastric cancers. There was not found any significant correlation between the interval : onset of symptoms and surgery, and pTNM stage. The most frequent signs and symptoms were epigastric pain, weight loss, indigestion, fatigue, pallor and loss of appetite, each of them were found in more than 40% patients. Multivariate analysis of symptoms showed that weight loss (p=0.00638) was independently correlated to advanced pTNM stages. The number of signs and symptoms was significantly correlated to advanced pTNM stages (p=0.000026). This significant group of patients studied has maintained characteristics encountered in populations with higher incidence of gastric adenocarcinoma, men being more frequently affected, distal localization and intestinal histologic type being encountered more frequently.


Subject(s)
Adenocarcinoma/diagnosis , Stomach Neoplasms/diagnosis , Adenocarcinoma/complications , Adenocarcinoma/pathology , Adenocarcinoma/surgery , Adult , Age Factors , Aged , Aged, 80 and over , Anorexia/etiology , Asthenia/etiology , Dyspepsia/etiology , Female , Humans , Male , Middle Aged , Neoplasm Staging , Pain/etiology , Pallor/etiology , Prognosis , Retrospective Studies , Risk Factors , Sex Factors , Stomach Neoplasms/complications , Stomach Neoplasms/pathology , Stomach Neoplasms/surgery , Weight Loss
13.
Chirurgia (Bucur) ; 103(5): 529-37, 2008.
Article in Romanian | MEDLINE | ID: mdl-19260628

ABSTRACT

The aim of this study is to evaluate the morbidity and mortality in the surgical treatment of gastric cancer and the factors that could influencing them. We made a retrospective analysis of a group of 468 patients with gastric adenocarcinoma which have been operated in the 3RD Surgical Clinic-Cluj Napoca--01.01.1998-31.12.2003. We analyzed parameters related to patient, pTNM stage and type of treatment. Morbidity was significantly higher in these circumstances: elder patients, cases with lower serum levels of hemoglobin and total proteins, after Billroth II procedures; we found no significant differences of morbidity depending on gender, pTNM stage, type of intervention: simple or multiorgan resection, subtotal or total gastrectomy, radical or palliative procedure or only exploratory laparotomy, presence or absence of splenectomy or caudal pancreatectomy, D1 or D2 lymphadenectomy (in radical procedures), palliative resection or gastrojejunal bypass. Elder patients and male patients have had a mortality significantly higher; we found no significant differences of mortality depending on serum levels of hemoglobin and total proteins, pTNM stage, type of intervention: simple or multiorgan resection, subtotal or total gastrectomy, radical or palliative procedure or only exploratory laparotomy, presence or absence of splenectomy or caudal pancreatectomy, D1 or D2 lymphadenectomy (in radical procedures), type of restoring of the digestive continuity after subtotal gastrectomy, palliative resection or gastrojejunal bypass.


Subject(s)
Adenocarcinoma/mortality , Adenocarcinoma/surgery , Gastrectomy , Stomach Neoplasms/mortality , Stomach Neoplasms/surgery , Adenocarcinoma/pathology , Adult , Aged , Aged, 80 and over , Digestive System Surgical Procedures/methods , Female , Gastrectomy/methods , Gastroenterostomy/methods , Humans , Lymph Node Excision , Male , Middle Aged , Neoplasm Staging , Palliative Care/methods , Postoperative Complications/mortality , Postoperative Complications/surgery , Prognosis , Retrospective Studies , Risk Factors , Stomach Neoplasms/pathology , Survival Analysis , Treatment Outcome
14.
Chirurgia (Bucur) ; 103(6): 709-14, 2008.
Article in Romanian | MEDLINE | ID: mdl-19274920

ABSTRACT

Neoplasms of the body and tail of the pancreas are rarer in comparison to those occurring in the head of the pancreas, representing only 10% of the total number of pancreatic malignancies. They poses even in present one of the greatest therapeutic challenge for the surgeon as their diagnosis and treatment are difficult to be done mainly due to specific anatomic position of the pancreas as well as due to the absence of any specific symptomatology belonging to the tumors of the body and tail of the pancreas having smaller dimensions. Here we are presenting two cases of neoplasms of the body and tail of the pancreas from the archives of 3rd Surgical Clinic, Cluj Napoca, hereby illustrating the experience of this clinic in the domain of high class pancreatic surgery. The two patients, having 55 and 43 years of age respectively, were diagnosed with neoplasm of the body and tail of the pancreas for which they had undergone the procedure of distal pancreatectomy along with the resection of the spleen. Out of those two cases, the first case had an invasive process of the tumor in the region of the superior mesenteric vein for what it was performed a segmental resection of the superior mesenteric vein with a termino-terminal anastomosis of the remaining two proximal and distal ends, while the second case inspite of its large dimension of the tumor (approximately 10 c.m in diameter) did not have any loco-regional invasion or any kind of distal metastasis which rendered it possible for a radical intervention. The aim of this case presentation as well as the reviews of the literatures belonging to this specialised domain is to sustain the idea that pancreatic surgery should be performed in those specialised surgical centres having profound knowledge as well as all the existing information about the diagnostic procedures, therapeutic attitude and prognostic factors of this specific pathology.


Subject(s)
Carcinoma, Pancreatic Ductal/diagnosis , Carcinoma, Pancreatic Ductal/surgery , Pancreatectomy , Pancreatic Neoplasms/diagnosis , Pancreatic Neoplasms/surgery , Adult , Carcinoma, Pancreatic Ductal/pathology , Digestive System Surgical Procedures/methods , Female , Humans , Mesenteric Veins/surgery , Middle Aged , Neoplasm Staging , Pancreatectomy/methods , Pancreatic Neoplasms/pathology , Prognosis , Splenectomy , Treatment Outcome
15.
Rom J Intern Med ; 46(3): 229-37, 2008.
Article in English | MEDLINE | ID: mdl-19366082

ABSTRACT

BACKGROUND AND AIM: Case selection criteria for resection of liver metastasis after colorectal cancer are still incompletely elucidated and represent a subject of great interest recently. Our aim was to evaluate 2-year survival after resection and to identify the survival risk and prediction factors in those cases. METHODS: 63 patients diagnosed and undergoing liver resection for colorectal metastatic disease to the liver at the Surgical University Hospital No.3 (Cluj-Napoca, Romania) between 01.01.2002 and 31.12.2005 were included in the study. Exclusion criteria were: palliative treatment as well as surgical treatment performed in a different surgical centre. After the surgical treatment, patients were followed regularly using clinical assessment on a 3 monthly basis with abdominopelvic ultrasound or computerised tomography annually. The following variables were recorded: age, gender, coexisting medical diseases, blood tests results, tumour site, maximal tumour diameter after resection, duration of surgery, surgical procedure and the clinical outcome until last follow-up, including date of death where appropriate. RESULTS: 2-year post-operative survival was 65.1%. In univariate analysis: age (< 65 vs > = 65 years, p = 0.041), metastasis number (< 3 vs > = 3 tumors, p = 0.049), maximal tumor dimension (< 3 vs > = 3 cm, p = 0.047), glutamine-oxaloacetic transaminase (GOT) preoperative level (< 42 vs > = 42 mg/dl, p = 0.018) were significant factors correlated to median survival time. However, non of the above mentioned factors presented independent prediction power in multivariate analysis (Cox regression, p < 0.05). CONCLUSIONS: Our results support liver metastasis resection without prior case selection except for technically-operative criteria selection.


Subject(s)
Adenocarcinoma/surgery , Colorectal Neoplasms/pathology , Hepatectomy , Liver Neoplasms/surgery , Adenocarcinoma/secondary , Age Factors , Aged , Female , Follow-Up Studies , Hospitals, University , Humans , Kaplan-Meier Estimate , Liver Neoplasms/secondary , Male , Middle Aged , Neoplasm Staging , Prognosis , Retrospective Studies
16.
Chirurgia (Bucur) ; 102(1): 31-6, 2007.
Article in Romanian | MEDLINE | ID: mdl-17410727

ABSTRACT

In the III-rd Surgical Clinic Cluj-Napoca, during 1996-2005, there was operated laparoscopic 33 patients with hepatic hydatid cyst. The sex ratio was M10/F23, with a mean age of 34 years and with ages between 10 and 66 years. Hepatic echography was used in preoperative diagnosis. The hepatic hydatid cysts were situated in 9 cases in the left liver (II-III-IV Couinaud segments) and in 24 cases in the right liver (15 cases in the V-VI segments and 9 cases in the VII-VIII Couinaud segments). The laparoscopic treatment was performed by Lagrot pericystectomy at 31 patients and by ideal cystectomy at 2 patients. Around the cyst there were put switches impregnated with formalin 2% or hypertonic saline 20% to prevent peritoneal insemination. The cyst sterilization was done in most cases with hypertonic saline solution. The mean postoperative hospitalization was 5,6 days, with the range 1-21 days. Laparoscopic surgery with the well known advantages offers a good alternative to classic surgery in the treatment of hepatic hydatid cyst.


Subject(s)
Echinococcosis, Hepatic/surgery , Hospitals, University , Laparoscopy , Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Retrospective Studies , Treatment Outcome
17.
Chirurgia (Bucur) ; 102(6): 735-7, 2007.
Article in Romanian | MEDLINE | ID: mdl-18323238

ABSTRACT

The gastrojejunocolic fistula represents a clinical entity that occurs very rarely following gastro-jejunal anastomoses and manifests itself clinically and paraclinically by a severe malabsorption syndrome. The results of the physiopathological approach may be summed up as follows: reduced level of seric proteins, fluid and electrolytic depletion, deficiencies in the absorption of the vitamins soluble in fats and water, which may all vary from mildness to severeness, depending on the flow rate of the fistula. Most often, the diagnosis is set by performing barium enema, which is positive for all cases, whereas the barium passage is less efficient, enabling diagnosis in only 33% of the cases. The radiological image may be reduced on principle to one single sign: the abnormal fistulous trajectory (barium passes from the stomach directly into the colon or the enema fills the gastric lumen). It is recommended that surgical treatment be performed in a single stage, by resecting the entire fistula and re-establishing the gastro-jejunal and colic continuity. We report a case of gastrojejunocolic fistula in a patient that underwent 2/3 gastric resection for gastric ulcer 9 years ago.


Subject(s)
Biliary Fistula/etiology , Gastric Fistula/etiology , Gastroenterostomy/adverse effects , Intestinal Fistula/etiology , Jejunal Diseases/etiology , Adult , Biliary Fistula/surgery , Gastric Fistula/surgery , Humans , Intestinal Fistula/surgery , Jejunal Diseases/surgery , Male , Reoperation , Treatment Outcome
18.
Chirurgia (Bucur) ; 100(3): 237-40, 2005.
Article in Romanian | MEDLINE | ID: mdl-16106930

ABSTRACT

The goal of the "Prospect" programme (sponsored by Pfizer) is to create possible evidence-based protocols related to the management of postoperative pain after certain type of surgical intervention (e.g. hernia repairs, hysterectomies, etc.). This article is introducing the protocol for laparoscopic cholecystectomy for both day-case and longer hospital admission cases. The protocol is designed for preoperative, intra and postoperative period, choosing only those measures which were effective for postoperative pain, published in the literature. We are also presenting an analyze of our 13,000 laparoscopic cholecystectomies, from "Prospect" protocol point of view, and what we should do to improve the management of postoperative pain.


Subject(s)
Analgesics/therapeutic use , Cholecystectomy, Laparoscopic , Pain, Postoperative/drug therapy , Cholecystectomy, Laparoscopic/adverse effects , Clinical Protocols , Dipyrone/administration & dosage , Humans , Ketamine/administration & dosage , Ketoprofen/administration & dosage , Postoperative Nausea and Vomiting/drug therapy , Treatment Outcome
19.
Chirurgia (Bucur) ; 100(2): 187-9, 2005.
Article in Romanian | MEDLINE | ID: mdl-15957463

ABSTRACT

The porcelain gallbladder is uncommon type of chronically inflamed gallbladder wall considered to be associated with a high frequency of adenocarcinoma and subsequently not suitable for a laparoscopic approach. In 12,000 patients chosen for a laparoscopic cholecystectomy 4 porcelain gallbladders were diagnosed. In 2 cases the laparoscopic approach was successful. One conversion was due to an unconfirmed suspicion of gallbladder cancer and the other one to a fistula between the gallbladder and the common bile duct. Patients with a preoperative diagnosis of porcelain gallbladder must not be excluded from the laparoscopic approach yet a low threshold for conversion must be maintained in those with a cancer suspicion.


Subject(s)
Calcinosis/surgery , Cholecystectomy, Laparoscopic , Gallbladder Diseases/surgery , Adenocarcinoma/diagnosis , Adenocarcinoma/etiology , Adenocarcinoma/surgery , Aged , Calcinosis/complications , Calcinosis/diagnosis , Gallbladder Diseases/complications , Gallbladder Diseases/diagnosis , Gallbladder Neoplasms/diagnosis , Gallbladder Neoplasms/etiology , Gallbladder Neoplasms/surgery , Humans , Middle Aged , Retrospective Studies , Treatment Outcome
20.
J Oral Rehabil ; 32(2): 134-40, 2005 Feb.
Article in English | MEDLINE | ID: mdl-15641980

ABSTRACT

The clinical performance of light polymerized resin-based composites (RBCs) is greatly influenced by the quality of the light curing unit (LCU). A commonly used unit for polymerization of RBC material is the halogen LCUs. However, they have some drawbacks. Development of new blue superbright light emitting diodes (LED LCU) of 470 nm wavelengths with high light irradiance offers an alternative to standard halogen LCU. The aim of this study is compared the effectiveness of LED LCU and halogen LCU on the degree of conversion (DC) of different resin composites [two hybrid (Esthet-X, Filtek Z 250), four packable (Filtek P60, Prodigy Condensable, Surefil, Solitaire), one ormocer-based resin composite (Admira)]. The DC values of RBCs polymerized by LED LCU and halogen LCU ranged approximately from 61.1 +/- 0.4 to 50.6 +/- 0.6% and from 55.6 +/- 0.7 to 47.4 +/- 0.5%, respectively. Significantly higher DC of RBCs except Surefil and Filtek Z 250 was obtained for LED LCU compared with halogen LCU (P < 0.05). Surefil and Filtek Z 250 exhibited no statistically significant difference values between LED LCU and halogen LCU (P > 0.05). As a result, it was observed that the performance of LED LCU used in the study was satisfactory clinically and had sufficient irradiance to polymerize RBCs (hybrid, packable and ormocer based) at 2 mm depth with a curing time of 40 s.


Subject(s)
Composite Resins/radiation effects , Light , Dental Restoration, Permanent/methods , Halogens , Humans , Methacrylates/radiation effects , Polymers , Siloxanes/radiation effects
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