ABSTRACT
We describe the case of a 70-year-old man with unicentric grade 1 epitheloid hemangioendothelioma (EH) of the bone that favourably responded to intravenous pamidronate as a single agent. After 6 years of follow-up, the patient was in complete remisssion. We suggest that use of bisphosphonates should be considered in the treatment of osteolytic EH.
Subject(s)
Antineoplastic Agents/therapeutic use , Bone Neoplasms/drug therapy , Diphosphonates/therapeutic use , Hemangioendothelioma/drug therapy , Osteolysis/drug therapy , Aged , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/pathology , Disease-Free Survival , Fingers/pathology , Hemangioendothelioma/diagnostic imaging , Hemangioendothelioma/pathology , Humans , Male , Osteolysis/diagnostic imaging , Osteolysis/pathology , Pamidronate , Radiography , Treatment Outcome , Wrist/pathologySubject(s)
Antirheumatic Agents/therapeutic use , Arthritis, Rheumatoid , Aspergillosis, Allergic Bronchopulmonary , Immunoglobulin G/therapeutic use , Receptors, Tumor Necrosis Factor/therapeutic use , Recombinant Fusion Proteins/therapeutic use , Antifungal Agents/therapeutic use , Arthritis, Rheumatoid/complications , Arthritis, Rheumatoid/drug therapy , Arthritis, Rheumatoid/pathology , Aspergillosis, Allergic Bronchopulmonary/etiology , Aspergillosis, Allergic Bronchopulmonary/pathology , Aspergillosis, Allergic Bronchopulmonary/therapy , Drainage , Etanercept , Female , Humans , Immunocompromised Host , Middle Aged , Pneumothorax , Pyrimidines/therapeutic use , Treatment Outcome , Triazoles/therapeutic use , VoriconazoleABSTRACT
Synovial hemangioma of the knee joint was diagnosed in a young woman 15 years after the first signs. The principal clinical manifestation involved repeated episodes of hemorrhagic joint effusion. MRI is the exploration of choice for this vascular tumor of the synovial membrane, although a pathology study is needed to confirm the diagnosis. Cure is achieved with surgical resection.
Subject(s)
Hemangioma, Cavernous/diagnosis , Knee Joint , Synovial Membrane , Adult , Angiography , Arthroscopy , Biopsy , Chronic Disease , Female , Hemangioma, Cavernous/complications , Hemangioma, Cavernous/surgery , Humans , Magnetic Resonance Imaging , Pain/etiology , Patient Selection , Tomography, X-Ray ComputedABSTRACT
Acute calcific tendinitis is uncommon in children. Clinical manifestations are similar to those in adults. The abrupt onset, functional impairment, and frequent presence of fever suggest an infection. Radiographic findings establish the diagnosis, obviating the need for further investigations.
Subject(s)
Calcinosis/diagnostic imaging , Tendinopathy/diagnostic imaging , Acute Disease , Arm/diagnostic imaging , Child , Child, Preschool , Female , Humans , Male , RadiographySubject(s)
Aneurysm, False/complications , Hemarthrosis/etiology , Tibial Arteries/pathology , Adult , Aneurysm, False/diagnosis , Ankle/diagnostic imaging , Ankle/pathology , Exostoses/complications , Exostoses/diagnostic imaging , Hemarthrosis/diagnosis , Humans , Magnetic Resonance Imaging , Male , Radiography , Synovial Membrane/pathologySubject(s)
Amyloidosis/complications , Arthritis, Rheumatoid/complications , Hematuria/etiology , Urinary Bladder Diseases/complications , Amyloidosis/diagnosis , Arthritis, Rheumatoid/diagnosis , Fatal Outcome , Female , Follow-Up Studies , Hematuria/diagnosis , Humans , Middle Aged , Urinary Bladder Diseases/diagnosisABSTRACT
A 75-year old man with rheumatoid arthritis developed bronchiolitis obliterans organizing pneumonia (BOOP), which responded to treatment with prednisolone (1 mg/kg/d) and cyclophosphamide (100 mg/d).
Subject(s)
Arthritis, Rheumatoid/complications , Cryptogenic Organizing Pneumonia/etiology , Aged , Anti-Inflammatory Agents/therapeutic use , Antirheumatic Agents/therapeutic use , Cryptogenic Organizing Pneumonia/diagnostic imaging , Cryptogenic Organizing Pneumonia/drug therapy , Cyclophosphamide/therapeutic use , Drug Therapy, Combination , Female , Humans , Prednisolone/therapeutic use , Radiography, Thoracic , Tomography, X-Ray ComputedABSTRACT
Eight patients with an age ranging from 72 to 83 years, seen in an outpatient clinic over a one-year period for stress fractures of the proximal tibia responsible for acute knee pain and effusion were studied retrospectively. Plain roentgenograms were often normal at presentation but subsequently showed sclerosis of the proximal tibia. Radionuclide bone scanning was the most useful investigation for early diagnosis. Potential risk factors were advanced: age, genu varum or valgum, overweight and vitamin D deficiency. Stress fracture of the proximal tibia should be considered in elderly patients with knee pain, effusion and normal roentgenograms. Elimination of weight-bearing ensures healing of the fracture.
Subject(s)
Aging , Fractures, Stress/complications , Knee Joint/pathology , Synovitis/etiology , Tibial Fractures/complications , Aged , Aged, 80 and over , Aging/physiology , Diagnosis, Differential , Female , Fractures, Stress/diagnosis , Fractures, Stress/physiopathology , Humans , Knee Joint/diagnostic imaging , Male , Radiography , Retrospective Studies , Risk Factors , Synovial Fluid/metabolism , Synovitis/physiopathology , Tibial Fractures/diagnosis , Tibial Fractures/physiopathologySubject(s)
Etidronic Acid/adverse effects , Osteitis Deformans/drug therapy , Osteolysis/chemically induced , Aged , Femur , Humans , Male , Time FactorsSubject(s)
Edema/etiology , Polyarteritis Nodosa/complications , Synovitis/etiology , Aged , Antigen-Antibody Reactions , Humans , Male , Synovitis/immunologySubject(s)
Median Nerve , Neurilemmoma/diagnosis , Peripheral Nervous System Neoplasms/diagnosis , Adult , Aged , Humans , MaleABSTRACT
Visceral Larva migrans is a human infection by the larvae of dog ascarids or, more rarely, ascarids of other animal species. It is endemic in France. Two cases which respectively manifested as acute oligoarthritis and inflammatory myalgia with increased muscle enzyme levels are reported. Manifestations of the minor forms of this infestation are reviewed.
Subject(s)
Larva Migrans, Visceral/complications , Rheumatic Diseases/parasitology , Toxocara canis , Adult , Animals , Digestive System Diseases/diagnosis , Digestive System Diseases/parasitology , Female , Humans , Larva Migrans, Visceral/diagnosis , Larva Migrans, Visceral/drug therapy , Male , Middle Aged , Rheumatic Diseases/diagnosis , Rheumatic Diseases/etiology , Toxocara canis/isolation & purificationSubject(s)
Amyloidosis/etiology , Plasmacytoma/complications , Skin Neoplasms/complications , Synovial Membrane , Aged , Female , HumansABSTRACT
The purpose of this study was to determine magnetic resonance imaging (MRI) features of osteoid osteomas and to evaluate the place of MRI in the diagnostic workup of suspected osteoid osteoma by comparing its diagnostic value with that of computed tomography (CT). Nine patients with radioclinical features highly suggestive of osteoid osteoma were investigated using bone scintigraphy, CT scan and MRI. MRI sequences were weighted for T1 (TR: 500 ms-TE: 34 ms), T2 (TR:2000 ms-TE:50-100 ms) and T1 after intravenous injection of gadolinium-DTPA contrast material. The appearance of the nidus and surrounding area were analyzed, as well as the accompanying inflammatory reaction involving the bone marrow, soft tissues or synovium. All patients had surgical treatment. Clinical recovery was achieved in every case. Histological studies confirmed the diagnosis of osteoid osteoma in 7 patients. In two cases, histological confirmation was not obtained and the exact nature of the lesion therefore remained in doubt, although clinical and scintigraphic findings as well as the subsequent course were consistent with the diagnosis of osteoid osteoma. In 5 cases, MRI proved inferior to CT scan for detecting the nidus. MRI disclosed edema of the bone marrow not seen on CT scan sections in 5 cases, edema of the soft tissues in three cases, and synovitis with joint effusion in one patient with an epiphyseal osteoid osteoma. At present, MRI plays only an ancillary role in the diagnosis of osteoid osteoma, which rests on the concomitant use of bone scintigraphy and CT scan.(ABSTRACT TRUNCATED AT 250 WORDS)
Subject(s)
Bone Neoplasms/diagnosis , Magnetic Resonance Imaging , Osteoma, Osteoid/diagnosis , Adolescent , Adult , Bone Neoplasms/pathology , Bone Neoplasms/surgery , Female , Humans , Male , Osteoma, Osteoid/pathology , Osteoma, Osteoid/surgery , Tomography, X-Ray ComputedABSTRACT
Two typical cases of Parsonage-Turner syndrome with reflex sympathetic dystrophy syndrome and adhesive capsulitis of the shoulder are reported. The rarity of this combination is discussed.
Subject(s)
Brachial Plexus Neuritis/complications , Reflex Sympathetic Dystrophy/etiology , Shoulder Joint , Arthrography , Bone and Bones/diagnostic imaging , Brachial Plexus Neuritis/diagnosis , Bursitis/etiology , Electromyography , Humans , Male , Middle Aged , Radionuclide Imaging , Reflex Sympathetic Dystrophy/diagnosisABSTRACT
A case of reflex sympathetic dystrophy involving the hip with a pathologic fracture of the femoral neck in a pregnant patient is reported. The low incidence of this condition is underlined and its characteristics are reviewed. The role of increased fragility related to pregnancy is discussed.
Subject(s)
Femoral Neck Fractures/complications , Fractures, Spontaneous/complications , Hip , Pregnancy Complications , Reflex Sympathetic Dystrophy/complications , Adult , Female , Humans , PregnancyABSTRACT
A new case of simvastatin-induced acute rhabdomyolysis with heart failure after initiation of treatment with fusidic acid is reported. In most reported instances, statin treatment was initially well tolerated with muscle toxicity developing only after addition of another drug. The mechanism of this muscle toxicity is unelucidated but involvement of a decrease in tissue Co enzyme Q is strongly suspected.
Subject(s)
Anticholesteremic Agents/adverse effects , Lovastatin/analogs & derivatives , Rhabdomyolysis/chemically induced , Aged , Female , Humans , Lovastatin/adverse effects , SimvastatinABSTRACT
On the basis of 193 cases of psoriatic arthropathy, the authors sought the incidence and rapidity of onset of signs suggestive of this type of rheumatic disorder when there are radiological lesions of the fingers and toes. They conclude that when such radiological lesions exist, signs suggestive of psoriatic arthropathy are frequent (90%), early (85% of cases of psoriatic arthropathy present for less than 5 years) and predominantly involve the distal parts of the fingers and toes (85.5%). The authors consider that the signs which distinguish psoriatic arthropathy from rheumatoid arthritis are due to an extrasynovial process of enthesopathic origin.