ABSTRACT
The aim of this study was to evaluate the larval expulsion, larvicidal effect, retention rate of dead larvae and overall efficacy of sarolaner on the treatment of myiasis caused by New World screwworm Cochliomyia hominivorax in naturally infested dogs. Eight Beagle dogs received a single dose of saroalner 40â¯mg, with dosage ranging from 2.7â¯mg/kg to 3.7â¯mg/kg. Evaluations occurred every 15â¯min in the first hour, every hour for up to 6â¯h, and after 24â¯h of treatment. At 24â¯h post-treatment, total wound cleaning was performed, including removal and counting of remaining live and dead larvae. The animals received antibiotic, analgesic and wound cleaning support until complete wound healing. The average expulsion of the larvae was 50.9 % occurring mainly after 4â¯h of treatment. The larvicidal effect was 70.6 % at 6â¯h after treatment and 100 % at 24â¯h. The mean retention rate of dead larvae of sarolaner was 33.9 %, The overall efficacy was 100 %, thus making sarolaner an excellent treatment option in myiasis caused by C. hominivorax larvae in dogs.