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The feasibility of using pathobiome strains as live biotherapeutic products for human use.

Jin, Pengfei; Lin, Xiong; Xu, Wenfeng; Li, Kangning; Zhao, Xiaoxiao; Guo, Sirui; Zhao, Zinan; Jiang, Lujie; Liao, Feng; Chang, Longgang; Wang, Min; Liu, Yanmin; Huang, Shaolei; Chen, Zhangran; Ji, Fusui.

Imeta ; 3(3): e202, 2024 Jun.

Article in English | MEDLINE | ID: mdl-38898988

ABSTRACT

The evaluation of pathobiome strains should be conducted at the strain level, involving the identification of the functional genes, while considering the impact of ecological niche and drug interactions. The safety, efficacy, and quality management of live biotherapeutic products (LBPs), especially pathobiome strains, have certain peculiarities. Promising development methods include the recombinant LBP and active metabolites.

Editorial: The role of omics characteristics in the diagnosis, treatment, and prognosis of autoimmune diseases.

Wu, Qinglong; Ning, Kang; Zhao, Xiaoxiao; Liao, Feng; Wang, Min; Chang, Longgang; Liu, Yanmin; Chen, Jinmiao; Zhao, Ming; Chen, Zhangran.

Front Immunol ; 13: 1069918, 2022.

Article in English | MEDLINE | ID: mdl-36405699

Subject(s)

Autoimmune Diseases , Humans , Prognosis , Autoimmune Diseases/diagnosis , Autoimmune Diseases/genetics , Autoimmune Diseases/therapy

Editorial: Multi-Omics Study on Gut Microbiota Related to Faecal Microbiota Transplantation.

Wu, Jingtong; Wang, Leyi; Wei, Yanling; Yang, Jialiang; Chen, Zeyou; Hao, Pei; Lv, Yinyin; Wang, Min; Liao, Feng; Chang, Longgang; Liu, Yanmin; Chen, Zhangran.

Front Microbiol ; 13: 944879, 2022.

Article in English | MEDLINE | ID: mdl-35814686

ABSTRACT

Subject(s)

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