Acquired Perforating Dermatosis and Dermatology Life Quality Index in Patients Receiving hemodialysis.

INTRODUCTION: Acquired perforating dermatosis (APD) is a frequent disorder in hemodialysis patients and the effect on the quality of life is poorly described. We investigated the prevalence of APD in hemodialysis patients, measured and compared APD-associated quality of life. METHODS: We developed a prospective, observational, and descriptive study. We invited patients over the age of 18 in hemodialysis. Data was obtained from their electronic file and a dermatological examination was performed. The Dermatology Life Quality Index (DLQI) was applied. Descriptive analysis of demographic variables, clinical features, and dermoscopy findings, as well as comparison of DLQI scores, was made. RESULTS: The sample consisted of 46 patients, with a prevalence of APD of 11%. Patients with APD were leaner and younger compared to patients without APD. The time on hemodialysis was longer in patients with APD compared to those without APD, with a median of 90 versus 32 months (p = 0.015). The impact on quality of life was greater in patients with APD compared to those without APD, with some effect in all patients with APD and 33% in patients without APD (p = 0.001). Patients with APD had more frequent pruritus compared to those without APD (p = 0.007). CONCLUSIONS: Age, time on hemodialysis and BMI are associated with the presence of APD. Patients with APD had a higher prevalence of pruritus and a greater impact on quality of life in dermatology compared to patients without APD.

Oral squamous cell carcinomas and oral potentially malignant disorders: A Latin American study.

OBJECTIVE: To determine the frequency of oral squamous cell carcinoma (OSCC) associated or not with oral potentially malignant disorders (OPMD), and the epidemiological profile and traditional risk factors in Latin America. METHODS: A retrospective observational study was conducted in 17 Latin American centres. There were included cases of OSCC, analysing age, gender, OSCC and their association with previous OPMD. Clinicopathological variables were retrieved. The condition of sequential-OSCC versus OSCC-de novo (OSCC-dn) was analysed concerning the aforementioned variables. Quantitative variables were analysed using Student's t-test, and qualitative variables with chi-square. RESULTS: In total, 2705 OSCC were included with a mean age of 62.8 years old. 55.8% were men. 53.75% of the patients were smokers and 38% were common drinkers. The lateral tongue border was the most affected site (24.65%). There were regional variations in OPMD, being leukoplakia the most frequent. Of the overall 2705 OSCC cases, 81.4% corresponded to OSCC-dn, while s-OSCC were 18.6%. Regarding lip vermillion SCC, 35.7% corresponded to de novo lip SCC and 64.3% were associated with previous OPMD. CONCLUSIONS: In Latin America, OSCC-dn seems to be more frequent with regional variations of some clinical and histopathological features. Further prospective studies are needed to analyse this phenomenon.

Sporotrichosis in Argentina: clinical and epidemiological analysis / Esporotricosis en Argentina: análisis clínico y epidemiológico

Introduction: Sporotrichosis is an implantation mycosis caused by Sporothrix spp. It is distributed worldwide and can be found in vegetation and soil. The most frequent route of infection is by trauma with elements contaminated with fungal propagules. Since domestic cats are the most affected animals and can transmit this infection to humans, sporotrichosis is considered a zoonosis. Clinical presentations include nodular lymphangitis, fixed cutaneous, pulmonary (rare), and disseminated (exceptional). Objectives: To analyze the epidemiology of sporotrichosis in Argentina during 2010 and 2022. To describe the clinical presentation, diagnostic methods, and treatment of cases diagnosed during this period. To know the circulating genotypes and to observe possible associations with the geographic location where the infection was acquired. Materials and methods: Analytical, retrospective, and observational study. We analyzed the medical records of patients with sporotrichosis from 12 health institutions in Argentina, between 2010 and 2022. Results: We present 54 cases in which the most frequent clinical form was nodular lymphangitis, and the treatment of choice was itraconazole. Conventional diagnosis was made in all cases. Culture of clinical samples was more sensitive than direct examination because it allowed the isolation of Sporothrix spp. in all 54 cases. Molecular identification was performed in 22 cases, with Sporothrix schenkii sensu stricto being the most frequently isolated species. Conclusions: This study allowed to know the epidemiology of this mycosis in Argentina, as well as the availability of diagnostic methods and the treatment of choice.

Introducción: La esporotricosis es una micosis de implantación causada por Sporothrix spp. Este se encuentra distribuido mundialmente y se puede encontrar en la vegetación y en el suelo. La ruta más frecuente de adquisición de la infección es por traumatismos con elementos contaminados con propágulos del hongo. Los gatos domésticos son los animales más afectados y pueden transmitirla a los humanos, por lo que es considerada una zoonosis. Las formas clínicas incluyen: la linfangítica nodular, la cutánea fija, la pulmonar (poco habitual) y la diseminada (excepcional). Objetivo: Analizar la epidemiología de la esporotricosis en Argentina entre los años 2010 y 2022. Describir la presentación clínica, los métodos de diagnóstico y el tratamiento de los casos diagnosticados en este período. Conocer los genotipos circulantes y observar su relación con el lugar geográfico de adquisición de la infección. Materiales y métodos. Se llevó a cabo un estudio analítico, retrospectivo y observacional, en el que se analizaron las historias clínicas de los pacientes con esporotricosis de 12 instituciones de salud de Argentina, entre los años 2010 y 2022. Resultados: Se presentan 54 casos en los que la forma clínica más frecuente fue la linfangítica nodular y el tratamiento de elección fue el itraconazol. En todos los casos se realizó diagnóstico convencional. El cultivo de las muestras clínicas resultó más sensible que el examen directo, ya que permitió el desarrollo de Sporothrix spp. en los 54 casos. En 22 casos se hizo identificación molecular y Sporothrix schenkii sensu stricto fue la especie más frecuentemente aislada. Conclusiones: Este estudio permitió conocer la epidemiología de esta micosis en Argentina, así como la disponibilidad de métodos diagnósticos y el tratamiento de elección.

Esporotricosis en Argentina: análisis clínico y epidemiológico / Sporotrichosis in Argentina: clinical and epidemiological analysis

Introducción. La esporotricosis es una micosis de implantación causada por Sporothrix spp. Este se encuentra distribuido mundialmente y se puede encontrar en la vegetación y en el suelo. La ruta más frecuente de adquisición de la infección es por traumatismos con elementos contaminados con propágulos del hongo. Los gatos domésticos son los animales más afectados y pueden transmitirla a los humanos, por lo que es considerada una zoonosis. Las formas clínicas incluyen: la linfangítica nodular, la cutánea fija, la pulmonar (poco habitual) y la diseminada (excepcional). Objetivo. Analizar la epidemiología de la esporotricosis en Argentina entre los años 2010 y 2022. Describir la presentación clínica, los métodos de diagnóstico y el tratamiento de los casos diagnosticados en este período. Conocer los genotipos circulantes y observar su relación con el lugar geográfico de adquisición de la infección. Materiales y métodos. Se llevó a cabo un estudio analítico, retrospectivo y observacional, en el que se analizaron las historias clínicas de los pacientes con esporotricosis de 12 instituciones de salud de Argentina, entre los años 2010 y 2022. Resultados. Se presentan 54 casos en los que la forma clínica más frecuente fue la linfangítica nodular y el tratamiento de elección fue el itraconazol. En todos los casos se realizó diagnóstico convencional. El cultivo de las muestras clínicas resultó más sensible que el examen directo, ya que permitió el desarrollo de Sporothrix spp. en los 54 casos. En 22 casos se hizo identificación molecular y Sporothrix schenkii sensu stricto fue la especie más frecuentemente aislada. Conclusiones. Este estudio permitió conocer la epidemiología de esta micosis en Argentina, así como la disponibilidad de métodos diagnósticos y el tratamiento de elección.

Introduction. Sporotrichosis is an implantation mycosis caused by Sporothrix spp. It is distributed worldwide and can be found in vegetation and soil. The most frequent route of infection is by trauma with elements contaminated with fungal propagules. Since domestic cats are the most affected animals and can transmit this infection to humans, sporotrichosis is considered a zoonosis. Clinical presentations include nodular lymphangitis, fixed cutaneous, pulmonary (rare), and disseminated (exceptional). Objective. To analyze the epidemiology of sporotrichosis in Argentina during 2010 and 2022. To describe the clinical presentation, diagnostic methods, and treatment of cases diagnosed during this period. To know the circulating genotypes and to observe possible associations with the geographic location where the infection was acquired. Materials and methods. Analytical, retrospective, and observational study. We analyzed the medical records of patients with sporotrichosis from 12 health institutions in Argentina, between 2010 and 2022. Results. We present 54 cases in which the most frequent clinical form was nodular lymphangitis, and the treatment of choice was itraconazole. Conventional diagnosis was made in all cases. Culture of clinical samples was more sensitive than direct examination because it allowed the isolation of Sporothrix spp. in all 54 cases. Molecular identification was performed in 22 cases, with Sporothrix schenkii sensu stricto being the most frequently isolated species. Conclusions. This study allowed to know the epidemiology of this mycosis in Argentina, as well as the availability of diagnostic methods and the treatment of choice.

Plastic residues produced with confirmatory testing for COVID-19: Classification, quantification, fate, and impacts on human health.

In March 2020, several international organizations started making recommendations regarding the need for prompt coronavirus-based diagnosis in order to prevent its spread among the world's population. The most widely used test for confirmation of COVID-19 is real-time PCR (RT-PCR). This technique uses plastic supplies in its procedures, which are 100% disposable to avoid cross-contamination and biological risks. The scientific community has become increasingly worried because of the environmental impacts associated with the current COVID-19 pandemic, such as medical plastic residues. We classified and estimated the amount of plastic residues generated as a consequence of COVID-19 diagnostic tests and analyzed the relationships of the plastics generated with number of confirmed cases, population size, and gross domestic product in each country. We evidenced that the RT-PCR generates 37.27 g of plastic residues per sample. All patients COVID-19 tested with RT-PCR have generated 15,439.59 tons of plastic residue worldwide, until August 2020. The plastic residues generated by the COVID-19 tests have no relation with size population or gross domestic product of the countries. There is also no relationship between the plastic residues generated by the COVID-19 tests and the confirmed cases. About 97% of the plastic residues from diagnostic tests for coronavirus are incinerated due to their hazardous nature to humans, but toxic chemicals are released into the environment during the process. In the short term, there is a need to reduce plastic waste and improve controls of gas emissions from incineration plants in countries where there is a deficit. In the long term, biodegradable biomedical manufacturing that are free of releasing toxic chemicals when they are incinerated, must be considered.

Development of New Experimental Dentifrice of Peruvian Solanum tuberosum (Tocosh) Fermented by Water Stress: Antibacterial and Cytotoxic Activity.

AIM: "Tocosh" is a potato that has undergone a process of hydraulic oxidation that enhances its antimicrobial properties so that this natural resource can be used in medical sciences. The aim of this study was to develop and evaluate the antibacterial and cytotoxic activity of a new experimental tooth based on Solanum tuberosum "Tocosh" on the cell lines 3T3 and DU145. MATERIALS AND METHODS: To evaluate the cytotoxicity, cell cultures 3T3 and DU145 were used. Cell viability was determined by the MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) in a medium containing 10% calf serum where the cells were preincubated at a concentration of 1 × 106 cells/mL in culture medium for 3 hours at 37°C and 6.5% CO2. Then, the absorbance was measured using a microplate reader where the formazan crystals were diluted with acidic and cold isopropanol, and quantified in an ELISA reader. To evaluate the antibacterial effect, the Kirby Bauer inhibition halos method was used on strains of S. aureus (ATCC 25923), S. mutans (ATCC 25175), and S. mitis (ATCC 49456). RESULTS: Solanum tuberosum (tocosh) was not cytotoxic because it only had one CC50 at the concentration of 0.26927 mg/mL and 0.26845 mg/mL for the cell lines 3T3 and DU145, respectively. Tocosh toothpaste (TD) has an antibacterial effect against S. aureus and S. mutans. CONCLUSION: The new ecological dentifrice was not cytotoxic since it did not alter cell viability because its CC50 was only 0.268 and 0.269 µg/mL for the 3T3 and DU145 cell lines, respectively; however, it presented an optimal antimicrobial activity against the oral strains evaluated. CLINICAL SIGNIFICANCE: This research has great potential for clinical use because this new dentifrice has antimicrobial activity against different oral germs. How to cite this article: Mayta-Tovalino F, Sedano-Balbin G, Romero-Tapia P, et al. Development of New Experimental Dentifrice of Peruvian Solanum tuberosum (Tocosh) Fermented by Water Stress: Antibacterial and Cytotoxic Activity. J Contemp Dent Pract 2019;20(10):1206-1211.

Una mirada a la calidad de vida y salud de las educadoras de párvulos / A look to the life and health quality of kindergarten teachers

INTRODUCCIÓN: La medición de la calidad de vida desde la perspectiva de la salud y su relación en el ámbito laboral de las Educadoras de Párvulos como agentes fundamentales en el desarrollo cognitivo y socioemocional en la primera infancia es de relevancia, pues existen aspectos claves para conseguir una buena calidad pedagógica en concordancia con los anhelos de las nuevas políticas en educación implementadas en Chile. OBJETIVO: determinar con qué factores se asocian la calidad de vida relacionada con la salud de las Educadoras de Párvulos, desde los elementos sociodemográficos y laborales concernientes en sus actividades profesionales. MÉTODO: Diseño metodológico descriptivo, correlacional, de corte transversal en 156 Educadoras de Párvulos de una comuna de Chillán, Chile. Resultados: las Educadoras de Párvulos, que se desempeñan casi en su totalidad en el aula, refieren un rol físico, función física y rol emocional óptimo, con una regular vitalidad y función social, una buena salud mental y mal dolor corporal, con relaciones altamente significativas en la función física con el ausentismo y dependencia laboral, y significativa con el número de niños a cargo y años laborales. También altamente relacionados en forma significativa el dolor corporal y los días de ausentismo, significativamente la vitalidad y el número de niños a cargo, y el rol emocional con los días de ausentismo laboral, entre otros. DISCUSIÓN: Estos antecedentes podrían ser determinantes en la orientación de las prácticas educativas y ponen en manifiesto que las nuevas disposiciones y políticas gubernamentales no aseguran condiciones que propicien una buena calidad de vida docente.

INTRODUCTION: the measurement of life quality from a health perspective and its relationship on the labor field of Kindergarten Teachers as main agents on the cognitive and socio emotional development in early childhood, is relevant, since there are key aspects in order to get a good pedagogical quality according to the desires of the new educational politics implemented in Chile. OBJECTIVE: to determinate which factors are associated to the quality of life related to the health of Kindergarten Teachers, from sociodemographic and labor elements concerning their professional activities. Method: descrip tive methodological design, correlational, cross sectional in 156 Kindergarten Teachers from a commune in Chillán, Chile. RESULTS: the Kindergarten Teachers, who mostly perform in the classroom, relate a physical role, physical function and an optimal emotional role, with a regular vitality and social function, a good mental health and body ache, with highly meaningful relations in the physical function with absenteeism and labor dependency. Also, body ache and days of absenteeism are highly related in a meaningful way, as well as vitality and the amount of kids they are in charge of, and the emotional role with the days of labor absenteeism, among others. DISCUSSION: these antecedents may be determinant on the guidance of the teaching practices and show that the new regulations and governmental politics do not ensure conditions that promote good quality in docent life.

Association Between Self-Perceived Oral Health and Clinical Indicators.

PURPOSE: To determine whether self-perceived oral health impact and satisfaction measure oral health in the same way as do clinical indicators in adults and older adults. MATERIALS AND METHODS: The population consisted of adult patients aged 20 to 59 years receiving care at "Juan Pablo II" Health Care Centre and older adult patients aged 60 or more years from the home for the elderly "Virgen del Amor Hermoso", Lima, Peru. The indices Oral Impacts on Daily Performance (OIDP) and Oral Satisfaction Scale of 0-10 (OSS 0-10) were used to evaluate perceived impact of and satisfaction with oral health. In addition, the following internationally validated criteria established by the World Health Organization (WHO) were used as clinical indicators: Decayed-Missing-Filled Teeth (DMFT) Index, O'Leary's Hygiene Index, Community Periodontal Index, Motivation to Hygiene Index, Denture Situation Index, Need for Denture Index, Denture Hygiene Index and Oral Mucosal Lesion Index. RESULTS: Forty-four adults and 53 older adults participated. OIDP showed that the greatest perceived difficulty in daily performance was "eating and enjoying food" (adults: 77.3% and older adults: 79.2%). The OSS 0-10 showed that among adults, 43.1% were dissatisfied, 20.5% were neutral and 36.4% were satisfied, while among older adults, 45.3% were dissatisfied, 22.6% were neutral and 32.1% were satisfied. A statistically significant association was found between OSS 0-10 and 1. DMFT index in adults; 2. upper denture situation in older adults; and 3. denture hygiene in older adults. A highly significant inverse linear correlation was found between OIDP and OSS 0-10 in adults and older adults. CONCLUSION: The perceived impact of oral health does not have a demonstrable association with oral health problems when used as an instrument for measuring oral health status, whereas perceived satisfaction with oral health has a better association with the clinical indicators.

Manejo bajo sedación consciente de quiste de erupción en infante / Management under conscious sedation of an infant with eruption cyst

El quiste de erupción es un quiste extra óseo justo antes de la erupción de los dientes, se presenta de color negro azulado, debido a su contenido sanguinolento. Los problemas clínicos causados por su presencia son: retraso de erupción y dolor durante la masticación. No precisa tratamiento si las lesiones desaparecen por sí solos al romperse espontáneamente, permitiendo la erupción dental, aunque no siempre sucede esto y en caso de dolor o infección. El objetivo del presente estudio fue reportar el caso de un infante de 1 año y 8 meses que presentaba quiste de erupción, con aparente buen estado de salud que fue referido a la Clínica de Postgrado de la Facultad de Odontología de la Universidad Nacional Mayor de San Marcos. El tratamiento quirúrgico de elección fue la ulectomía bajo sedación consciente, la excisión simple del quiste de erupción se realizó a nivel del diente 63, cuyo propósito fue evacuar su contenido y eliminar la presión intracística. Se realizó la monitorización del proceso de erupción dental para asegurar un desarrollo adecuado y evolución favorable, devolviendo la salud de los tejidos blandos y manteniendo una buena salud oral.

It is called eruption cyst, follicular growth just before the eruption of teeth, this lesion cystic extra-bone type is presented in black-blue color, due to its bloody content. Clinical problems caused by the presence of cyst are delayed eruption and pain during chewing. No treatment required if the lesions disappear on their own to break spontaneously, allowing tooth eruption, except in case of infection. The aim of this study was to report the case of an infant patient of one year-old and 8 months, with good overall health, referring to the Specialty Pediatric Dentistry, Faculty of Dentistry at Universidad National Mayor of San Marcos. The surgical treatment was indicated ulectomy under conscious sedation, the simple excision of the eruption cyst was performed at the level of the tooth 63, whose purpose was to evacuate their contents and removing the intracistic pressure. The dental eruption process was monitored to ensure proper development and favorable evolution, restoring the health of soft tissues and maintaining good oral health.

Los pacientes del programa alivio del dolor y cuidados paliativos: razones y significados para enfermeras/os / Patients of the pain relief and palliative care programme: reasons and meaning for nurses

Objetivo: Estudio exploratorio de abordaje cualitativo, cuyo propósito fue comprender razones y significados que tiene para el profesional de enfermería el trabajar en el Programa Alivio del Dolor y Cuidados Paliativos. Material y método: A una muestra de 32 profesionales de Centros de Salud Familiar de Chillan se aplicó, mediante técnica Delphi, un cuestionario sociodemográfico y preguntas abiertas. Analizadas en base a Minayo, se originaron dos Escala de Likert. Resultados: Entre los discursos emitidos destacan el compromiso, los conocimientos, la entrega, la vocación y cumplir con cierto perfil; significa desgaste y no se permanece indiferente frente al dolor; reconocen la formación de pregrado, pero necesitan mayor capacitación por ser un área compleja; los pacientes enfrentan complicaciones y es difícil enfrentarlas solos; dar tranquilidad y paz permite serenidad en los últimos momentos y la carga emocional, espiritual y física es más llevadera; etapa de gran vulnerabilidad; el rol cobra importancia en lo clínico y en lo humano al entregar apoyo emocional en fallecimiento y duelo; se requiere coordinación efectiva entre los niveles de atención; no están todos los recursos; el trabajo tiene tiempo limitado, por tanto deben existir horas definidas. Conclusiones: Conocer significados, razones profesionales y/o personales permitirá diseñar estrategias y aportar a la formación de pregrado y postítulo en el área; es necesario aumentar número de enfermeras/os dedicados a este programa, para optimizar la calidad del cuidado de enfermería y satisfacer las necesidades de pacientes cuando enfrentan una enfermedad oncológica incurable avanzada.

Objective: An exploratory study with a qualitative approach, whose purpose was to understand the reasons and meanings that working in the Pain Relief and Palliative Care Programme has for nursing professionals. Methods: By using a Delphi technique, a sociodemographic questionnaire and open questions were applied to a sample of 32 professionals of Family Health Centers of Chillán. Based on Minayo's theme analysis, they originated two Likert Scales. Results: Among the main concepts obtained are commitment, knowledge, dedication, vocation and the idea of fulfilling a certain profile; this means wearing yourself out and not remaining indifferent to pain; they recognize undergraduate training, but they need more training, since it is a complex area; patients face complications and it is tough to face them alone; giving the patients peace and calm allows them to have serenity in their last moments; thus, the emotional, spiritual and physical burden is more bearable; period of great vulnerability; the nurse's role becomes important in human as well as clinical terms as emotional support is provided in times of death and mourning; effective coordination between levels of care is required; not all resources are available; there are time limitations; therefore, times must be assigned. Conclusions: Learning about nurses' meanings and professional and/or personal reasons will allow for the development of strategies and will contribute to undergraduate and post-graduate formation in this area; it is necessary to increase the number of nurses dedicated to this programme so as to optimize the quality of nursing care and meet the needs of patients when faced with an advanced incurable cancer disease.

Bacterias en superficies contactadas durante las tomas radiográficas intraorales / Bacteria in contacting surfaces during intraoral radiographies procedures

Determinar la presencia de bacterias mediante el análisis microbiológico en las superficies contactadas por el operador durante la toma y procesado de radiografías intraorales en diferentes momentos del día en el Servicio de Radiología Oral de la UPCH. Materiales y métodos: Se realizó un muestreo en nueve superficies del servicio de radiología oral. Las muestras se tomaron en dos momentos por el mismo investigador; al inicio y al finalizar las actividades en el servicio, se realizó el hisopado de las superficies con Caldo de Tripticasa Soya (TSB). Las muestras fueron inoculadas e incubadas en tres medios de cultivos (Agar Plate Count, Agar Sangre Cordero y Agar Cetrimide). Luego se realizó el conteo respectivo de Unidad Formadoras de Colonias (UFC) y también se realizó la tinción Gram. Resultados: Se encontró una alta cantidad concentración de bacterias (4180 UFC/mL) y hongos en el servicio radiología oral. Los cocos gram positivos fueron los microorganismos encontrados con más frecuencia y los bacilos gram negativos fueron menos encontradas. Conclusiones: Existe una gran contaminación de bacterias en el servicio de radiología oral. Al finalizar las actividades disminuye la cantidad de bacterias, pero aumenta la variedad de bacterias...

Determinate the presence of bacteria through a microbiological analysis of contacting surfaces in a radiology service from the operator during the taking and process of intraoral radiographies in different moments of the day. Materials and methods: A sample was taken from nine surfaces of the oral radiography service. Samples were taken with a cotton stick swap with Triptic Soy Broth (TSB) in two different moments by the same investigator; at beginning and that the end of activities. The samples were inoculated and incubated in three different cultivar measures (Plate Count Agar, Sheep Blood Agar and Cetrimide Agar) and also Gram stein was realized. Results: A high concentration of bacteria (4180 UFC/mL) and fungus was found in the oral radiology service. The coccus gram-positive was most frequently found microorganism and bacillus gram-negative was poorly found microorganism in this study. Conclusions: A high of contamination with bacteria was found in the oral radiology service. At the end of activities of the day, decrease the quantity of bacteria, but increase variety of bacteria...

Dulce Wireless Tijuana: A Randomized Control Trial Evaluating the Impact of Project Dulce and Short-Term Mobile Technology on Glycemic Control in a Family Medicine Clinic in Northern Mexico.

BACKGROUND: The global epidemic of diabetes calls for innovative interventions. This study evaluated the effectiveness of the Project Dulce model, with and without wireless technology, on glycemic control and other clinical and self-reported outcomes in patients with poorly controlled type 2 diabetes in Mexico. SUBJECTS AND METHODS: Adults with type 2 diabetes and a glycated hemoglobin A1c (HbA1c) level of ≥8% were recruited from Family Medical Unit #27 of the Instituto Mexicano del Seguro Social (IMSS) in Tijuana, México, and randomly assigned to one of three groups: Project Dulce-only (PD); Project Dulce technology-enhanced with mobile tools (PD-TE); or IMSS standard of care/control group (CG). Clinical and self-reported outcomes were assessed at baseline, Month 4, and Month 10. Time-by-group interactions and within-group changes were analyzed. RESULTS: HbA1c reductions from baseline to Month 10 were significantly greater in PD-TE (-3.0% [-33 mmol/mol]) and PD (-2.6% [-28.7 mmol/mol]) compared with CG (-1.3% [-14.2 mmol/mol]) (P = 0.009 and 0.001, respectively). PD-TE and PD also exhibited significant improvement in diabetes knowledge when compared with CG (P < 0.05 for both). No statistically significant differences were detected between PD and PD-TE on these indicators (P = 0.54 and 0.86, respectively). Several within-group improvements were observed on other clinical and self-report indicators but did not vary significantly across groups. CONCLUSIONS: Project Dulce with and without wireless technology substantially improved glycemic control and diabetes knowledge in high-risk patients with type 2 diabetes in a Mexican family medical unit, suggesting that integrating peer-led education, nurse coordination, and 3G wireless technology is an effective approach for improving diabetes outcomes in high-risk populations.

Enfermedad periodontal en pacientes diabéticos tipo 2 con y sin obesidad en Lima, Perú / Periodontal disease in type 2 diabetic patients with and without obesity from Lima, Perú

Determinar si la enfermedad periodontal afecta más a pacientes diabéticos tipo 2 con obesidad que a los pacientes sin obesidad. Material y métodos: La población estuvo conformado por 170 pacientes con diagnóstico de Diabetes Mellitus (DM) tipo 2; fueron divididos en dos grupos 85 diabéticos obesos y 85 diabéticos no obesos: el grupo obesos fue de 55 mujeres y 30 hombres mientras que el grupo sin obesidad fue de 37 mujeres y 48 hombres. Se utilizó el Índice Periodontal Comunitario Modificado y la ficha de registro de datos aprobados por la OMS, la evaluación clínica se realizó tomando en cuenta, profundidad de las bolsas y la presencia de furca dental. Resultados: De los 85 pacientes con obesidad, el 83,53% presentó bolsas periodontales de 4-5 mm y el 16,47% presentó bolsas > o = 6 mm, mientras que en el grupo sin obesidad el 90,59% presentó bolsas de 4-5 mm, el 7,06% presentó bolsas > o = 6 mm y el 2,35% no presentó bolsas. Conclusión: No hay diferencias en los signos de enfermedad periodontal en pacientes con diabetes mellitus tipo 2 con obesidad y sin obesidad...

To determine the presence and characteristics of periodontal disease in patients with type 2 diabetes mellitus with and without obesity. Material and Methods: Population consisted of patients diagnosed with Diabetes Mellitus type 2 (DM); 170 patients were divided among 85 obese diabetic patients and 85 diabetic patients not obese, obese patients 55 were women and 30 were men, in the non-obese group 37 were female and 48 male cases. Community Periodontal Index Modified and data recording sheet approved by WHO were used, clinical evaluation was performed taking into account, pocket depth and the presence of dental bifurcation. Results: Periodontal pockets of 4-5 mm in obese patients were 83.53% and 16.47% presented pockets >o = 6 mm, while in the group without obesity 90.59% showed pockets of 4-5 mm and 7.06% presented pockets >o = 6 mm while 2.35% (2 cases) had no pockets. Conclusion: No differences in the signs of periodontal disease patients with type 2 diabetes mellitus with obesity and non-obese...

Manifestaciones bucales y radiológicas en pacientes pediátricos con insuficiencia renal crónica / Clinical and radiographic oral manifestations in pediatric patients with chronic renal failure

La insuficiencia renal crónica y su tratamiento traen como consecuencia la presencia de cambios metabólicos y fisiopatológicos, los cuales pueden afectar a nivel bucodental y a nivel óseo en pacientes pediátricos. Estos cambios pueden ser apreciados tanto clínica como radiográficamente. Dado que la insuficiencia renal crónica representa, al igual que otras enfermedades crónicas, un problema de salud pública, por su importante morbi-mortalidad y costo socioeconómico, es esencial conocer los procesos patológicos o alteraciones involucrados. El propósito de esta revisión es describir las manifestaciones bucales clínicas y radiológicas, que se pueden presentar en los pacientes pediátricos con insuficiencia renal crónica, para que estos problemas sean mejor identificados por el cirujano dentista como participante del cuidado multidisciplinario de los pacientes con este padecimiento renal...

Chronic renal failure and its treatment results in the presence of metabolic and pathophysiological changes, which can affect oral cavity, teeth and jaws in pediatric patients. These changes can be assessed clinically and radiographically. Since chronic renal failure is, like other chronic diseases, a public health problem, because of its high morbidity, mortality and socioeconomic costs, it is essential to know the pathological processes or alterations involved. The purpose of this review is to describe the clinical and radiographic oral manifestations, which may occur in pediatric patients with chronic renal failure, so that these problems are best identified by the dental surgeon as a member of the multidisciplinary care of patients with this renal disease...

Relación entre los cambios del ambiente laboral ocasionados postevento sísmico del 27 febrero 2010 y la presencia de ansiedad y estrés laboral en el profesional de enfermería / Relationship between the change of work environment caused by 27 february 2010 seismic post-event and the presence of anxiety and stress in professional nursing

Objetivo: Determinar la relación entre síntomas de ansiedad y estrés laboral en el profesional de enfermería de dos establecimientos hospitalarios de la Provincia de Ñuble con los cambios en el ambiente laboral postevento sísmico. Método: Estudio cuantitativo, correlacional, en 64 profesionales de enfermería. Se aplicó el Maslach Burnout Inventory, la escala de Ansiedad y Depresión de Goldberg y un cuestionario para identificar los cambios en el ambiente laboral postevento sísmico. Resultados: El 56,25% de los sujetos presentó síntomas de ansiedad, un 59,38% de depresión, el 84,38% un nivel medio de estrés. La modificación del espacio físico fue el cambio más estresante. El cambio en la calidad de los insumos utilizados, patología de los usuarios y en el flujograma de atención se asocian estadísticamente con la presencia de ansiedad en los profesionales de enfermería. Conclusión: El evento sísmico ocasionó diversas modificaciones en el ambiente laboral, cuyos cambios pueden ser relacionados con la generación de ansiedad en el profesional de enfermería, que es un pilar fundamental de todas las atenciones de salud; por tanto, en la medida que tengan buena salud mental sus prestaciones serán más efectivas, eficaces y oportunas, incrementando la calidad en la atención a los usuarios.

Objective: Determine the relationship between symptoms of anxiety and occupational stress in nursing professionals of two hospitals of the Province of Ñuble with changes in the work environment by seismic post-event. Method: quantitative and correlational study in 64 nurses. The Maslach Burnout Inventory, the Anxiety and Depression Scale of Goldberg and a questionnaire to identify changes in the work environment in seismic post-event, were applied. Results: 56.25% of the subjects had symptoms of anxiety, 59.38% of depression, 84.38% an average stress level. Modification of the physical space was the most stressful change. The change in the quality of supplies used, pathology of user and attention flowchart, associate statistically with the presence of anxiety in nurses. Conclusion: The seismic event caused several changes in the work environment, and those changes can be related to the generation of anxiety in the nursing professional, who is a cornerstone of all health care, therefore, as having good mental health their services will be more effective, efficient and timely, increasing the quality of care to users.

Malignant lymphoma of the oral cavity and the maxillofacial region: overall survival prognostic factors.

OBJECTIVE: To identify the overall survival and prognostic factors of malignant lymphoma of the oral cavity and the maxillofacial region. STUDY DESIGN: Clinical records data were obtained in order to determine overall survival at 2 and 5 years, the individual survival percentage of each possible prognostic factor with the actuarial technique, and the survival regarding the possible prognostic factors with the actuarial technique and the Log-rank and Cox's regression tests. RESULTS: Of 151 subjects, an overall survival was 60% at 2 years, and 45% at 5 years. The multivariate analysis demonstrated statistically significant differences for clinical stage (p=0.002), extranodal involvement (p=0.030), presence of human immunodeficiency virus (p=0.032), and presence of Epstein-Barr virus (p=0.010). CONCLUSION: The advanced clinical stage and the larger number of involved extranodular sites are related to a lower overall survival, as well as, the presence of previous infections such as the human immunodeficiency and the Epstein-Barr virus.

Propóleo Peruano: una nueva alternativa terapéutica antimicrobiana en Estomatología / Peruvian Propolis: a new alternative in dental antimicrobial therapy

El propóleo es una sustancia resinosa compleja constituida por una gran variedad de compuestos químicos (esteres, flavonoides etc.), su composición no es estable y varía según la fuente de procedencia. Además, una de las propiedades más importantes del propóleo es su actividad antibacteriana, la cual se le atribuye fundamentalmente a los flavonoides. El propóleo se conoce desde la más remota antigüedad y ha sido utilizado por diferentes culturas con diversas finalidades. Con el posterior desarrollo de la farmacéutica y tratamientos fitoterápicos existe un resurgimiento en su uso. Es por esa razón que en los últimos años se han realizado algunas investigaciones acerca de los productos provenientes de las abejas y sus potenciales beneficios para la salud oral. Por lo tanto, la presente revisión de la literatura recolecta la información disponible sobre la composición del propóleo según zona geográfica y la actividad antibacteriana que tiene el propóleo aplicado a la estomatología.

Propolis is a resinous substance complex consisting of a variety of chemical compounds (esters, flavonoids, etc.), it's composition is not stable and varies depending on the source. In addition, one of the most important properties of propolis is its activity antibacterial, which is attributed mainly to flavonoides. Propolis has been known since ancient times and has been used by different cultures for various purposes. With the subsequent development of pharmaceutical and herbal treatments there is a resurgence in its use. It is for this reason that in recent years have done some research about the products from the bees and their potential health benefits oral. Therefore, this literature review collects the available information on properties of propolis depends on geography and the antibacterial activity propolis has applied to dentistry.

Prognostic factors in patients with jaw sarcomas.

The aim of this study was to identify the prognostic factors related to the survival of patients with sarcomas of the jaw treated in the Dr. Eduardo Caceres Graziani National Institute for Neoplastic Diseases, Lima, Peru. Age, gender, delay in consultation, diagnostic delay, therapeutic delay, tumor size, tumor location, facial asymmetry, pain, treatment type, and histopathological diagnosis were all evaluated as possible prognostic factors that would influence survival in those with jaw sarcomas. In the analysis, the following was used: mortality tables, Kaplan-Meier's product-limit method, log-rank, and Breslow and Tarone-Ware tests; for the prognostic factors, Cox's Regression Model was used. The overall survival rate, with the patient being free from disease at two years, was 55%, and that at five years was 45%. In the independent analysis of the prognostic factors, four variables were statistically significant in influencing survival: gender (p = 0.043), histopathologic diagnosis (p = 0.019), tumor location (p = 0.019), and treatment type (p = 0.030). According to Cox's Regression Model for the multivariate analysis, statistically significant prognostic factors were: gender (p = 0.086), tumor location (p = 0.020), and treatment type (p = 0.092). Thus, the variables of gender, tumor location, and treatment type were determined to be predictive factors for prognosis of survival.