ABSTRACT
During a multicentric field trial involving 134 diagnosticans from 16 centres in a first phase and 38 diagnosticans from 5 centres in a second phase a preliminary version of the manual "Operational Psychodynamic Diagnosis (OPD)" was tested. Focussing on feasibility, practicability and interrater-reliability the different axes of the new system were assessed as comparatively easy to use. The goodness of fit for diagnostic categories and the confidence in the diagnostic process showed a sufficient acceptance of the system. The percentage and chance-corrected inter-rater-reliability coefficients were acceptable for the most axes. It could be demonstrated that interrater-reliability depends on the degree of experiences with the OPD approach. Therefore a systematic training is necessary to use the system.
Subject(s)
Mental Disorders/diagnosis , Psychiatric Status Rating Scales/statistics & numerical data , Psychoanalytic Theory , Adult , Diagnosis, Differential , Female , Germany , Humans , Male , Mental Disorders/classification , Mental Disorders/psychology , Middle Aged , Psychometrics , Reproducibility of ResultsABSTRACT
Employing two different techniques--Al-RAST and RAST inhibition test--we studied semi-depot extracts of grass pollen from six producers. On one hand, we measured the amount of allergens absorbed by Al(OH)3 gel; on the other hand, we determined the quantity of allergens solved in the aqueous phase. Furthermore, we checked up the continuous release of allergens from the depot by means of a simple in vitro model. The six different semi-depot extracts revealed different amounts of allergens in the depot (Al[OH]3) as well as in the aqueous phase. As we measured the continuous release of allergens, we found that all six extracts behaved nearly identically regarding their function as depots, but were different respecting the released amount of allergens. Summing up, it may be said that therapy extracts--analogous to previously examined test extracts--show differences with regard to their allergenic activities but very similar properties in respect to their function as depots.
