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OBJECTIVE: To investigate the relationship between work readiness and work well-being for newly graduated nurses and the mediating role of emotional labor and psychological capital in this relationship. METHODS: A cross-sectional survey was conducted in mainland China. A total of 478 newly graduated nurses completed the Work Readiness Scale, Emotional Labour Scale, Psychological Capital Questionnaire, and Work Well-being Scale. Descriptive statistical methods, Pearson correlation analysis, and a structural equation model were used to analyze the available data. RESULTS: Newly graduated nurses' work readiness was significantly positively correlated with work well-being (r = 0.21, p < 0.01), deep acting (r = 0.11, p < 0.05), and psychological capital (r = 0.18, p < 0.01). Emotional labor and psychological capital partially mediated the relationship between work readiness and work well-being. Additionally, emotional labor and psychological capital had a chain-mediating effect on the association. CONCLUSIONS AND CLINICAL RELEVANCE: Work readiness not only affects newly graduated nurses' work well-being directly but also indirectly through emotional labor and psychological capital. These results provide theoretical support and guidance for the study and improvement of newly graduated nurses' work well-being and emphasize the importance of intervention measures to improve work readiness and psychological capital and the adoption of deep-acting emotional-labor strategies.
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AIMS: This study aimed to investigate the associations between perfectionism and undergraduate nursing students' academic procrastination, the mediating effects of self-efficacy and the moderating role of resilience. DESIGN: A cross-sectional survey. METHODS: The survey was conducted from March to May 2022 with a sample of 587 undergraduate nursing students in two undergraduate universities in China. A descriptive statistical approach, Pearson's correlation analysis and the Hayes' PROCESS Macro model 4 and 14 were used to analyse the available data. RESULTS: Adaptive perfectionism and maladaptive perfectionism negatively and positively predicted academic procrastination in nursing undergraduates, respectively. Self-efficacy played a partially mediating role in the association between adaptive perfectionism and academic procrastination. Furthermore, resilience played a moderating role in the association between adaptive perfectionism and academic procrastination. CONCLUSIONS: Maladaptive perfectionism and low levels of resilience and self-efficacy may increase the risk of academic procrastination among nursing undergraduates. Nursing educators can take measures to decrease the risk of academic procrastination among nursing undergraduate students by guiding them to cultivate adaptive perfectionism tendencies and improve their self-efficacy and resilience. IMPACT: The findings of this study can be used to develop targeted coping and prevention measures for nursing educators to reduce the incidence of academic procrastination among nursing undergraduates. PATIENT OR PUBLIC CONTRIBUTION: Five hundred eighty-seven undergraduate nursing students from two undergraduate universities participated in the study and responded to questions on perfectionism and academic procrastination, etc.
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Education, Nursing, Baccalaureate , Perfectionism , Procrastination , Students, Nursing , Humans , Self Efficacy , Cross-Sectional StudiesABSTRACT
BACKGROUND: People's high requirements for medical care and the difficult academic tasks associated with the nursing profession require nursing students to have stronger learning motivation. PURPOSE: This study aimed to investigate the effect of perfectionism on the learning motivation of undergraduate nursing students and to explore the mediating factors influencing these two variables. METHOD: A total of 1366 nursing students from four undergraduate universities in Henan Province, China, were surveyed from May to July 2022. We conducted Pearson's correlation analysis and a regression analysis using PROCESS Macro Model 6 to explore the relationships among perfectionism, efficacy, psychological resilience, and learning motivation. RESULTS: The results indicated that perfectionism affected undergraduate nursing students' learning motivation not only directly but also indirectly through self-efficacy and psychological resilience. CONCLUSION: The results of this study offer certain theoretical support and guidance for research and interventions pertaining to undergraduate nursing students' learning motivation.
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Education, Nursing, Baccalaureate , Perfectionism , Resilience, Psychological , Students, Nursing , Humans , Motivation , Self Efficacy , Students, Nursing/psychology , Cross-Sectional StudiesABSTRACT
BACKGROUND: Spinal cord injury (SCI) causes nearly all patients to suffer from protracted disabilities. An emerging therapeutic strategy involving the recruitment of endogenous neural stem cells (NSCs) has been developed. However, endogenous NSCs in the adult spinal cord differentiate into mostly astrocytes after traumatic injury, forming glial scars, which is a major cause of regeneration failure in SCI. Thus, understanding which factors drive the activation and differentiation of endogenous NSCs after SCI is critical for developing therapeutic drugs. METHODS: The infiltration, state, and location of CD8+ T cells in spinal cord after traumatic injury were analyzed by flow cytometry and immunofluorescence (IF) staining. The Basso Mouse Scale (BMS) scores and rotarod testing were used for motor behavioral analysis. NSCs were co-cultured with CD8+ T cells. EdU assay was used to detect proliferative cells. Western blotting was used to analyze the expression levels of STAT1, p-STAT1, and p27. ChIP-seq and ChIP-qRT-PCR analyses were used to detect the downstream of STAT1. Nestin-CreERT2::Ai9 transgenic mice were used to genetic lineage tracing of Nestin+ NSCs after SCI in vivo. RESULTS: A prolonged increase of activated CD8+ T cells occurs in the injured spinal cords. The behavioral analysis demonstrated that the administration of an anti-CD8 antibody promotes the recovery of locomotor function. Then, we discovered that CD8+ T cells suppressed the proliferation of NSCs and promoted the differentiation of NSCs into astrocytes by the IFN-γ-STAT1 pathway in vitro. ChIP-seq and ChIP-qRT-PCR analysis revealed that STAT1 could directly bind to the promoters of astrocyte marker genes GFAP and Aldh1l1. Genetic lineage tracing of Nestin+ NSCs demonstrated that most NSCs differentiated into astrocytes following SCI. Depleting CD8+ T cells reduced the differentiation of NSCs into astrocytes and instead promoted the differentiation of NSCs into oligodendrocytes. CONCLUSION: In conclusion, CD8+ T cells suppressed the proliferation of NSCs and promoted the differentiation of NSCs into astrocytes by the IFN-γ-STAT1-GFAP/Aldhl1l axis. Our study identifies INF-γ as a critical mediator of CD8+ T-cell-NSC cross talk and a potential node for therapeutic intervention in SCI.
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This study aimed to explore the effect of prosocial behaviours on Chinese undergraduate nursing students' subjective well-being (SWB) and examine the roles of psychological resilience and coping styles. The sample for this study included 683 nursing students from two undergraduate universities in Henan Province, China. SWB, prosocial behaviours, psychological resilience, and coping styles were assessed by the Index of Well-Being, the Prosocial Behavioural Tendency Scale, the Connor-Davidson Resilience Scale, and the Simplified Coping Style Questionnaire, respectively. We adopted Pearson's correlation analysis and the PROCESS Macro Model 81 in regression analysis to explore the relationships among prosocial behaviours, psychological resilience, coping styles, and SWB. Prosocial behaviours of undergraduate nursing students had a positive predictive effect on SWB; psychological resilience and coping styles both were the mediating variable between prosocial behaviours and undergraduate nursing students' SWB; psychological resilience and coping styles played a chain mediating role between the prosocial behaviours and SWB of undergraduate nursing students. The results indicated that prosocial behaviours not only directly affected the SWB of undergraduate nursing students but also affected the SWB of undergraduate nursing students via psychological resilience and coping styles. These results offer certain theoretical support and guidance for the research and improvement of undergraduate nursing students' SWB and emphasize the importance of interventions to increase prosocial behaviours, improve psychological resilience, promote positive coping styles, and address negative coping styles.
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Education, Nursing, Baccalaureate , Resilience, Psychological , Students, Nursing , Humans , Students, Nursing/psychology , Altruism , East Asian People , Adaptation, Psychological , Surveys and QuestionnairesABSTRACT
AIM: To quantitatively synthesize the correlation between posttraumatic growth and resilience among breast cancer patients and explore the potential moderators affecting the relation. DESIGN: A meta-analysis of cross-sectional studies. METHODS: This meta-analysis followed the Preferred Reporting Items for Systematic Review and Meta-Analyses 2020 guidelines. This meta-analysis was carried out by searching Chinese and English databases of China National Knowledge Infrastructure, WANFANG DATA, Chongqing VIP Information Co., Ltd., PubMed, Embase, Web of Science, and PsycINFO from inception to February 25, 2022. Pooled Pearson's correlation coefficients between posttraumatic growth and resilience was calculated by the Stata software (version 17.0) using the random effects model. RESULTS: Seventeen studies including 4156 breast cancer patients were identified. A high positive correlation was found between posttraumatic growth and resilience (r = 0.448, 95% CI: 0.370-0.519, p < 0.001), and region and publication type significantly moderated the relation.
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Breast Neoplasms , Posttraumatic Growth, Psychological , Resilience, Psychological , Female , Humans , Cross-Sectional StudiesABSTRACT
BACKGROUND: How to kindle the learning enthusiasm of nursing students and reduce the incidence of academic procrastination is an important factor in reducing student attrition and improving the quality of nursing education. OBJECTIVES: To investigate the mediating role of coping style and resilience on the association between parenting styles and academic procrastination among nursing undergraduates. METHODS: A cross-sectional study of 683 nursing undergraduates was conducted in China from March to May 2022. Parenting styles, coping style, resilience, and academic procrastination were measured using questionnaires. Descriptive analysis, Pearson's correlation analysis and Hayes' PROCESS Macro in SPSS 25.0 were used to test the model. RESULTS: Positive parenting style had a significantly direct effect on academic procrastination and through three significantly indirect pathways: (1) through positive coping style (B = - 0.048, 95% CI: - 0.074 to - 0.025), accounting for 14.71% of the total effect; (2) through negative coping style (B = - 0.044, 95% CI: - 0.071 to - 0.021), accounting for 13.64% of the total effect; and (3) through resilience (B = - 0.074, 95% CI: - 0.107 to - 0.044), accounting for 22.82% of the total effect. Moreover, negative parenting style had a significantly direct effect on academic procrastination and through two significantly indirect pathways: (1) through negative coping style (B = 0.056, 95% CI: 0.032 to 0.086), accounting for 21.73% of the total effect, and (2) through resilience (B = 0.028, 95% CI: 0.004 to 0.055), accounting for 10.93% of the total effect. CONCLUSIONS: Intervention measures to reduce the academic procrastination of nursing undergraduates should include the evaluations of coping styles and resilience of nursing students and cultivation strategies to promote their positive coping styles and resilience.
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Knowledge hiding is one of the dilemmas of organizational knowledge management. For nurses, knowledge hiding behavior is not conducive to improving the quality and efficiency of their work and hinders the innovation of nursing services. Based on the social exchange theory, the current study constructed a moderated mediation model by taking psychological safety and felt obligation as mediating variables, and traditionality as moderating variable, and explored the mechanism of feeling trusted affecting knowledge hiding behavior. The empirical research based on 285 nurses from China shows that feeling trusted is negative correlate with knowledge hiding behavior; feeling trusted can negatively affect knowledge hiding by enhancing psychological safety and felt obligation; traditionality can positively moderate the relationship between feeling trusted and felt obligation, and feeling trusted has a stronger positive influence on felt obligation of highly traditional nurses; traditionality has no significant moderating effect between feeling trusted and psychological safety. Theoretically, this study supplements the influencing factors of knowledge hiding, examines the complex mechanism between feeling trusted and knowledge hiding and supplements the boundary conditions for feeling trusted to play its role from the perspective of individual characteristics (i.e., traditionality). From the perspective of practical implication, this study suggests that managers should pay attention to using trust strategies to enhance subordinates' psychological safety and felt obligation, especially for highly traditional nurses, thus reducing knowledge hiding.
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Background: Previous studies have not investigated the role of resilience and coping style on the association between maladaptive perfectionism and academic procrastination among nursing undergraduates. However, how to mobilize the learning enthusiasm of nursing students and reduce the incidence of academic procrastination is an important factor to reduce nursing loss and improve nursing quality. Objectives: To investigate the influence of maladaptive perfectionism, resilience and coping style on academic procrastination among Chinese undergraduate nursing students. Methods: A cross-sectional study was conducted. A convenience sampling method was used to select 665 nursing undergraduates from March to May 2022 in China. Maladaptive perfectionism, coping style, resilience, and academic procrastination were measured using questionnaires. The descriptive analysis, Pearson's correlation analysis and the Hayes' PROCESS Macro in SPSS 25.0 were used to test the model. Results: The results showed that nursing undergraduates' maladaptive perfectionism, resilience, positive coping style and academic procrastination were significantly correlated between every two variables, with coefficients ranging between -0.290 and 0.584. In addition, resilience played a partial mediating role in maladaptive perfectionism and academic procrastination, accounting for 15.70% of the total effect; in the meantime, this process was moderated by positive coping style. Conclusion: Maladaptive perfectionism positively predicted nursing undergraduates' academic procrastination; as a mediating mechanism with moderating, resilience and positive coping style further explained how maladaptive perfectionism promoted the academic procrastination of nursing undergraduates. Understanding this mechanism is of great significance for nursing educators to reduce the risk of academic procrastination in nursing undergraduates.
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Background: Smartphone addiction has become a social problem that affects the healthy growth of adolescents, and it is frequently reported to be correlated with self-esteem, self-control, and social support among adolescents. Methods: A meta-analysis was conducted by searching the PubMed, Web of Science, Embase, PsycINFO, PsycArticles, China National Knowledge Infrastructure (CNKI), WANFANG DATA, and Chongqing VIP Information Co., Ltd. (VIP) databases. Stata 16.0 was used to analyse the overall effect and test the moderating effect. Results: Fifty-six studies were included, involving a total of 42,300 participants. Adolescents' smartphone addiction had a moderately negative correlation with self-esteem (r = -0.25, 95% CI = -0.29 to -0.22, p < 0.001), a strong negative correlation with self-control (r = -0.48, 95% CI = -0.53 to -0.42, p < 0.001), and a weak negative correlation with social support (r = -0.16, 95% CI = -0.23 to -0.09, p < 0.001). Moderation analysis revealed that the correlation between adolescents' smartphone addiction and self-esteem was strongest when smartphone addiction was measured with the Mobile Phone Addiction Tendency Scale for College Students (MPATS; r = -0.38). The correlation between adolescents' smartphone addiction and self-control was strongest when self-control was measured with the Middle school students' Self-control Ability Questionnaire (MSAQ; r = -0.62). The effect of dissertations on smartphone addiction, self-control, and social support among adolescents was significantly larger than that of journal articles. The correlation between adolescents' smartphone addiction and social support was strongest when smartphone addiction was measured with the Mobile Phone Addiction Index (MPAI; r = -0.24). However, the correlations between adolescents' smartphone addiction and self-esteem, self-control, and social support were not affected by age or gender. Conclusion: There was a strong relationship between smartphone addiction and self-esteem, self-control, and social support among adolescents. In the future, longitudinal research should be carried out to better investigate the dynamic changes in therelationship between smartphone addiction and self-esteem, self-control, and social support. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42022300061.
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The question of how to improve the subjective well-being (SWB) of nursing students is an important factor for reducing nursing loss and improving nursing quality. The current study aimed to investigate the influence of parenting style and self-efficacy (SE) on SWB among Chinese nursing undergraduates. The moderating role of gender between parenting style and SWB was also examined. Descriptive analysis, Pearson's correlation analysis, and the Hayes' PROCESS Macro Model 4 and Model 5 were used to analyze the available data. A total of 665 nursing undergraduates (Mage = 19.86, SD = 1.19) completed questionnaires. The results showed that PPS was positively correlated with SWB (r = 0.421, p < 0.01), while NPS was negatively correlated with SWB (r = -0.167, p < 0.01). Meanwhile, SE was positively correlated with PPS (r = 0.167, p < 0.01) and negatively correlated with NPS (r = -0.175, p < 0.01). In addition, SE was positively correlated with SWB (r = 0.273, p < 0.01) and played a partial mediating role in the association between parenting style and SWB. Furthermore, gender moderated the direct effect of parenting style on SWB. Specifically, compared with male nursing students, parenting style has a greater influence on the SWB of female nursing students. These findings can be used to develop targeted improvement strategies for nursing educators to improve SWB levels among nursing undergraduates.
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Self Efficacy , Students, Nursing , Adult , China , Female , Gender Identity , Humans , Male , Parenting , Surveys and Questionnaires , Young AdultABSTRACT
Non-suicidal self-injury (NSSI) has attracted increasing attention due to its high detection rate, high risk and high repeatability. There is a need for the early identification of preventable occurrence factors, which is necessary to facilitate screening and intervention, especially to facilitate the early detection of high-risk individuals. This research aims to investigate the relationship between bullying behaviour and non-suicidal self-injury among children and adolescents by means of meta-analysis. The PubMed, Embase, Web of Science, SCOPUS, PsycINFO, CKNI and WAN FANG databases were searched from inception to 14 December 2021 for studies that explored the relationship between bullying behaviour and NSSI among children and adolescents. A total of 29 articles met the inclusion criteria of the meta-analysis, and 54 independent effect sizes were obtained, including 53,501 subjects. Victims [OR 2.46 (95% CI 2.14-2.83); p < 0.001], bullies [OR 2.12 (95% CI 1.37-3.27); p < 0.001], and bully-victims [OR: 2.98 (95% CI 1.85-4.82); p < 0.001] were more likely to have NSSI than uninvolved children or adolescents. In addition, analyses showed the absence of publication bias. In the victim group, the older the age was, the lower the risk of NSSI (z = - 3.74, p = 0.00). Gender does not play a moderating effect on the association between bullying behaviour and non-suicidal self-injury. The relationship between involvement in bullying and NSSI was demonstrated. By taking measures to prevent bullying, the incidence of NSSI in children and adolescents can be potentially reduced.
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Adolescent Behavior , Bullying , Crime Victims , Self-Injurious Behavior , Adolescent , Child , Humans , Self-Injurious Behavior/epidemiologyABSTRACT
Genistein is a naturally occurring phytoestrogen (soy or soybean products) that is classified as an isoflavone, and its structure is similar to that of endogenous estrogens; therefore, genistein can exert an estrogen-like effect via estrogen receptors. Additionally, genistein is a tyrosine kinase inhibitor, which enables it to block abnormal cell growth and proliferation signals through the inhibition of tyrosine kinase. Genistein is also an angiogenesis inhibitor and an antioxidant. Genistein has effects on kidney cells, some of the kidney's physiological functions, and a variety of kidney diseases. First, genistein exerts a protective effect on normal cells by reducing the inflammatory response, inhibiting apoptosis, inhibiting oxidative stress, inhibiting remodeling, etc., but after cell injury, the protective effect of genistein decreases or even has the opposite effect. Second, genistein can regulate renin intake to maintain blood pressure balance, regulate calcium uptake to regulate Ca2+ and Pi balances, and reduce vasodilation to promote diuresis. Third, genistein has beneficial effects on a variety of kidney diseases (including acute kidney disease, kidney cancer, and different chronic kidney diseases), such as reducing symptoms, delaying disease progression, and improving prognosis. Therefore, this paper reviews animal and human studies on the protective effects of genistein on the kidney in vivo and in vitro to provide a reference for clinical research in the future.
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Isoflavones , Kidney Diseases , Angiogenesis Inhibitors , Animals , Antioxidants/pharmacology , Calcium , Estrogens , Genistein/pharmacology , Humans , Isoflavones/pharmacology , Kidney Diseases/drug therapy , Phytoestrogens/pharmacology , Phytoestrogens/therapeutic use , Protein Kinase Inhibitors , Protein-Tyrosine Kinases , Receptors, Estrogen , ReninABSTRACT
Background: Smartphone addiction (SA) has become a social problem that affects peoples' quality of life and is frequently reported to be correlated with alexithymia, avoidant or anxious attachment styles, and subjective well-being. This study aimed to investigate the relationship between SA and alexithymia, attachment style, and subjective well-being. Methods: A meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The following electronic databases were searched: PubMed, Web of Science, Embase, PsycINFO, PsycArticles, China National Knowledge Infrastructure (CNKI), WANFANG DATA, and Chongqing VIP Information Co., Ltd. (VIP). Stata 16.0 was used to analyze the overall effect and test the moderating effect. Results: One hundred and ten studies were included, involving a total of 96,680 participants. SA had a significantly high positive correlation with alexithymia (r = 0.40), attachment anxiety (r = 0.37), and negative emotions (r = 0.31), and a low positive correlation with attachment avoidance (r = 0.17). In addition, there was a high negative correlation between SA and subjective well-being (r = -0.33) and a low negative correlation between SA, life satisfaction (r = -0.17), and positive emotions (r = -0.18). A moderation analysis revealed that age significantly moderated the relationship between SA and positive emotions. The tools for measuring SA significantly moderated the relationship between SA, alexithymia, attachment anxiety, and subjective well-being. Meanwhile, subjective well-being measurement tools significantly moderated the relationships between SA, subjective well-being, and negative emotions. Conclusion: SA was closely related to alexithymia, attachment style, and subjective well-being. In the future, longitudinal research can be conducted to better investigate the dynamic changes in the relationship between them. Systematic review registration: [www.crd.york.ac.uk/PROSPERO/], identifier [CRD42022334798].
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A complete chart of the chromatin regulatory elements of immune cells in patients with cancer and their dynamic behavior is necessary to understand the developmental fates and guide therapeutic strategies. Here, we map the single-cell chromatin landscape of immune cells from blood, normal tumor-adjacent kidney tissue and malignant tissue from patients with early-stage clear cell renal cell carcinoma (ccRCC). We catalog the T cell states dictated by tissue-specific and developmental-stage-specific chromatin accessibility patterns, infer key chromatin regulators and observe rewiring of regulatory networks in the progression to dysfunction in CD8+ T cells. Unexpectedly, among the transcription factors orchestrating the path to dysfunction, NF-κB is associated with a pro-apoptotic program in late stages of dysfunction in tumor-infiltrating CD8+ T cells. Importantly, this epigenomic profiling stratified ccRCC patients based on a NF-κB-driven pro-apoptotic signature. This study provides a rich resource for understanding the functional states and regulatory dynamics of immune cells in ccRCC.
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Carcinoma, Renal Cell , Kidney Neoplasms , CD8-Positive T-Lymphocytes , Carcinoma, Renal Cell/genetics , Chromatin/genetics , Humans , Kidney Neoplasms/genetics , NF-kappa BABSTRACT
In recent years, the problem of mobile phone addiction (MPA) has become increasingly serious among mainland Chinese adolescents. Studies have found that self-esteem may be related to MPA, but the conclusions are inconsistent. Consequently, this meta-analysis aims to explore the real relationship between self-esteem and MPA, and analyze the moderator variables. The relevant studies used in meta-analysis were obtained by searching China National Knowledge Infrastructure (CNKI), Wan Fang Data, Chongqing VIP Information Co., Ltd. (VIP), PubMed, Web of Science, Scopus, Medline and Embase. Then articles were screened and coded, and statistical analysis was carried out by Stata 16.0 software. A total of 45,765 participants from 64 articles were included in the research. Meta-analysis showed that there was a moderate negative correlation between self-esteem and MPA(r = -.25, 95%CI = -.29, -.21). Subgroup analysis and meta-regression analysis showed that the age and publication time can significantly moderate the relationship between self-esteem and MPA, but MPA measurement instrument, gender, region and publication type have no significant moderating effect. The current meta-analysis provided solid evidence that self-esteem was negatively correlated with MPA. Longitudinal studies are needed to clarify the causality between them, so as to make more specific practice and policy recommendations.
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Background: Social support is frequently reported to be correlated with loneliness, self-esteem, and resilience among left-behind children in mainland China. However, to date, there is no consensus on the extent to which those factors are correlated with social support among left-behind children. We thus performed a meta-analysis to quantitatively synthesize the previous findings. Methods: Two investigators systematically and independently searched PubMed, EMBASE, Web of Science, PsycINFO, Wan Fang, Chinese National Knowledge Infrastructure (CNKI) and China Science Technology Journal Database (VIP) on January 9, 2022. Pooled Pearson's correlation coefficients between social support and loneliness, self-esteem, and resilience were calculated by Stata 16.0 software using random effects model. Results: Forty-seven studies involving a total of 30 212 left-behind children were identified. A large degree of negative correlation was found between social support and loneliness [summary r: -0.36 (95% CI: -0.42- -0.30), p < 0.001]. Large positive correlations were found between social support and self-esteem, and resilience [self-esteem: summary r: 0.33 (95% CI: 0.24-0.41), p < 0.001; resilience: summary r: 0.45 (95% CI: 0.38-0.50), p < 0.001]. The pooled correlations revealed some discrepancies when stratified by some moderators. Sensitivity analysis also revealed the robustness of the findings. The Egger regression and Duvall and Tweedle trim-and-fill procedure suggest the absence of publication bias. Conclusion: The current meta-analysis provided solid evidence that social support has a high degree of negative correlation with loneliness and a high degree of positive correlation with self-esteem and resilience among left-behind children in mainland China. This indicated that left-behind children with high levels of social support tend to have lower levels of loneliness and higher levels of self-esteem and resilience. More studies, especially large prospective studies, are warranted to verify our findings.
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OBJECTIVE: Many studies have explored the relationship between insecure attachment and mobile phone addiction from different theoretical perspectives; however, the results have been different. This meta-analysis aimed to explore the relationship between insecure attachment and mobile phone addiction. METHODS: Studies published before November 2021 were identified through a systematic online search. A total of 22 studies, including 38 independent effect sizes were included from a systematic search of multiple databases, with a total sample size of 11,810 cases. Stata Version 16.0 was used for meta-analysis. RESULTS: The meta-analysis based on random-effects model showed that mobile phone addiction was highly positively associated with attachment anxiety (r = 0.395, 95%CI [0.345, 0.442]) and weakly positively correlated with attachment avoidance (r = 0.194, 95%CI [0.137, 0.250]). The relationship between attachment anxiety and mobile phone addiction and that between attachment avoidance and mobile phone addiction were both moderated by mobile phone addiction measures but not moderated by gender and attachment measures. CONCLUSION: There is a positive correlation between mobile phone addiction and insecure attachment. In the future, measures to prevent mobile phone addiction should focus on insecure attachment individuals and help them construct a healthy attachment relationship and secure attachment model.
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Cell Phone , Technology Addiction , Anxiety , HumansABSTRACT
Autophagy is a complex process of degradation of senescent or dysfunctional organelles in cells. Dysfunctional autophagy is associated with many diseases such as cancers, immune dysfunction, and aging. Hydrogen sulfide (H2S) is considered to be the third gas signal molecule after nitrous oxide and carbon monoxide. In recent years, H2S has been found to have a variety of important biological functions, and plays an important role in a variety of physiological and pathological processes. In this review, we review the recent role and mechanism of H2S in regulating autophagy in liver disorders, in order to provide a basis for further research in the future.
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Hydrogen Sulfide , Liver Diseases , Autophagy , Carbon Monoxide , Humans , Hydrogen Sulfide/metabolismABSTRACT
AIM: To investigate the influence of perceived organisational justice, professional identity and emotional labour on nurses' job performance. BACKGROUND: Previous studies have not explored the impact of professional identity and emotional labour on the relationship between perceived organisational justice and job performance. However, how to mobilize the enthusiasm of nurses and improve their job performance is the key for nursing managers to realize the sustainable development of hospitals. METHODS: A cross-sectional survey design was conducted. A total of 951 nurses from public hospitals in China participated in the survey from March-June 2021. The descriptive statistical approach, Pearson's correlation analysis and the PROCESS Macro Model 4 and 14 in regression analysis were used to analyse the available data. RESULTS: The results showed that nurses' perceived organisational justice, professional identity, emotional labour and job performance were significantly positive correlations between every two variables, with coefficients ranging between .24 and .75. Professional identity played a whole mediating role in perceived organisational justice and job performance, accounting for 98.04% of the total effect; meanwhile, this process was moderated by emotional labour. CONCLUSIONS: Perceived organisational justice positively predicted nurses' job performance; as a mediating mechanism with moderating, professional identity and emotional labour further explained how perceived organisational justice promoted the job performance of nurses. IMPLICATIONS FOR NURSING MANAGEMENT: This study highlighted the moderated mediation role of professional identity and emotional labour between nurses' perceived organisational justice and job performance. Understanding this mechanism has guiding significance for nursing managers to improve nurses' job performance.