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Pathol Biol (Paris) ; 63(4-5): 222-3, 2015 Sep.
Article in French | MEDLINE | ID: mdl-26088436

ABSTRACT

Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening dermatological conditions. Their most common cause is medication. However, in a small proportion of patients these dermatological conditions could be the first presentation of systemic lupus erythematosus. We now describe a 34-year-old patient who presented with manifestations of Stevens-Johnson as a first feature of systemic lupus erythematosus. Systemic lupus erythematosus reveled by Stevens-Johnson syndrome has been infrequently reviewed in the previous literature. This diagnosis should be considered when cutaneous adverse drug reactions occur without clear drug causality.


Subject(s)
Lupus Erythematosus, Systemic/complications , Stevens-Johnson Syndrome/etiology , Adult , Anemia/etiology , Arthralgia/etiology , Autoantibodies/blood , Complement C3/analysis , Critical Care , Facial Dermatoses/etiology , Female , Humans , Hydroxychloroquine/therapeutic use , Immunoglobulin G/analysis , Lupus Erythematosus, Systemic/blood , Lupus Erythematosus, Systemic/diagnosis , Lupus Erythematosus, Systemic/drug therapy , Lupus Erythematosus, Systemic/immunology , Methylprednisolone/therapeutic use , Mucositis/etiology , Prednisone/therapeutic use , Stevens-Johnson Syndrome/drug therapy
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