ABSTRACT
UNLABELLED: The aim of this study was to evaluate the presence or absence of a relationship between the variants of the course of IBS and their association with genetic polymorphisms of genes and intergenic interaction of cytokines. MATERIALS AND METHODS: The sample consisted of 81 patients, the diagnosis was verified according to the criteria of the Rome III, were isolated psychopathological, morphological complications, extra-intestinal symptoms. Polymorphism genotyping IL-1Ra, IL-b, IL-4, TNFa performed by PCR. Statistical treatment are a non-parametric analysis of multiple comparisons, hierarchical log-linear analysis. It is found out the relation between the clinical variants with morphological changes of the mucous membrane of the large intestine, the association between gender characteristics of patients with IBS is established and with genetic polymorphisms of cytokines.
Subject(s)
Interleukin 1 Receptor Antagonist Protein/genetics , Interleukin-1beta/genetics , Interleukin-4/genetics , Intestinal Mucosa/pathology , Intestine, Large/pathology , Irritable Bowel Syndrome , Polymorphism, Genetic , Tumor Necrosis Factor-alpha/genetics , Adult , Female , Humans , Irritable Bowel Syndrome/genetics , Irritable Bowel Syndrome/pathology , Male , Retrospective StudiesABSTRACT
The clinical use of the "autocapture" algorithm based on an automated pacemaker with the function of measurement of stimulation threshold and regulation of stimulus amplitude is discussed. The method is designed to prolong the operating time of the device. The algorithm itself is described and relevant medical literature on the subject is reviewed.
Subject(s)
Cardiac Pacing, Artificial/methods , Electric Stimulation/instrumentation , Pacemaker, Artificial/standards , Algorithms , Equipment Design , HumansABSTRACT
Different anesthesias were used in 197 patients operated for supraventricular tachiarrhythmias through a transvenous access. Hypnoanalgesia based on preventive injection of a potent nonnarcotic antiinflammatory agent xefocame (lornoxicame), drip infusion of propofol (2-3 mg/kg/h), and bolus injection of dormicum under conditions of spontaneous respiration proved to be the best method.
