ABSTRACT
The most common location of extragenital endometriosis is the bowel. Medical treatment may not provide long-term improvement in patients who are symptomatic, and consequently most of these patients may require surgical intervention. Over the past century, surgeons have continued to debate the optimal surgical approach to treating bowel endometriosis, weighing the risks against the benefits. In this expert review we will describe how the recommended surgical approach depends largely on the location of disease, in addition to size and depth of the lesion. For lesions approximately 5-8 cm from the anal verge, we encourage conservative surgical management over resection to decrease the risk of short- and long-term complications.
Subject(s)
Digestive System Surgical Procedures/methods , Endometriosis/surgery , Intestinal Diseases/surgery , Anal Canal/surgery , Conservative Treatment , Contraceptives, Oral, Combined/therapeutic use , Danazol/therapeutic use , Endometriosis/diagnostic imaging , Endometriosis/drug therapy , Endosonography , Estrogen Antagonists/therapeutic use , Female , Humans , Intestinal Diseases/diagnostic imaging , Intestinal Diseases/drug therapy , Laparoscopy , Leuprolide/therapeutic use , Magnetic Resonance Imaging , Ovulation Inhibition , Pelvic Pain , Postoperative Complications/prevention & control , Progestins/therapeutic use , Rectal Diseases/diagnostic imaging , Rectal Diseases/drug therapy , Rectal Diseases/surgery , UltrasonographySubject(s)
Fertility , Uterus , Female , Fertility Preservation , Humans , Neoplasms , Uterine Cervical NeoplasmsSubject(s)
Robotic Surgical Procedures , Robotics , Case-Control Studies , Female , Humans , Laparoscopy , Neoplasm Staging , Ovarian Neoplasms , Retrospective Studies , Treatment OutcomeABSTRACT
Endometriosis predominantly affects the pelvic reproductive organs but can also affect the urinary tract. A number of theories for the pathogenesis of endometriosis have been suggested, but the exact mechanisms remain elusive. Endometriotic lesions can be found on both the ureter and bladder, and the optimal therapeutic approach depends on the extent, depth, and location of these lesions. Medical approaches, including hormonal therapies such as GnRH agonists and oral contraceptives, tend to be a temporary measure, but can be useful in a preoperative setting or if the patient is unsuitable for surgery, and are also useful as a postoperative treatment. If surgical resection is deemed appropriate, laparoscopic management with or without robotic assistance of urological endometriosis is feasible and advisable. Newer techniques, such as nerve-sparing surgery, might help to decrease the risk of urinary complications following resection of deeply infiltrating endometriosis.
Subject(s)
Endometriosis/physiopathology , Endometriosis/therapy , Urologic Diseases/physiopathology , Urologic Diseases/therapy , Combined Modality Therapy , Cystoscopy , Endometriosis/diagnosis , Female , Humans , Urologic Diseases/diagnosis , Urologic Surgical Procedures , Urological Agents/therapeutic useSubject(s)
Cesarean Section , Cicatrix/surgery , Female , Fistula , Humans , Hysteroscopy , PregnancyABSTRACT
OBJECTIVES: Medical students have been shown to have high levels of psychological distress, including self-stigmatization and unwillingness to seek care. The authors hypothesized that a student-led curriculum involving personal mental illness experience, given during the first-year neuroscience course, and titled "Mental Illness Among Us (MIAU)," would reduce stigma of mental illness. METHOD: In 2010 and 2011, students completed voluntary pre- and post-MIAU surveys measuring attitudes regarding mental illness in relation to MIAU. Also, in 2011, the authors categorized topics mentioned in student responses to an open-ended, free-response question on the course final examination. RESULTS: Of 298 enrolled students, 250 submitted surveys that were matched pre- and post-intervention. Participants in the curriculum showed a significant difference in Social Distance, indicating an increased willingness to interact with individuals with mental illness, and a significant difference in the Mental Illness: Clinicians' Attitudes (MICA) score representing a stronger agreement with positive statements regarding mental illness. The non-participants' scores showed no changes in measures from pre- to post. Respondents most frequently reported that the neuroscience course prepared them to be a physician because it taught about compassion and the importance of treating the whole patient. CONCLUSION: The results indicate that participation in MIAU leads to a decrease in stigmatization of mental illness and a greater sense of compassion among UCSF medical students. This finding is consistent with previous research suggesting social and cognitive congruence among peers and peer-teachers can result in meaningful learning experiences. MIAU may represent a sustainable model to supplement current systems to promote well-being of medical trainees.