ABSTRACT
Background: Corona virus disease 2019 (COVID 19) is a potentially severe acute respiratory infection first reported in December 2019 in Wuhan, China. It is currently a global health issue and a public health emergency for the entire world, including Ethiopia. People with comorbidities of chronic disease are at higher risk for severe disease and death from this virus. Hence, in order to better control the COVID-19 pandemic, their understanding, attitude, and practice of COVID-19 prevention measures should be improved. Therefore, this study aimed to assess the knowledge, attitude, and practice of chronically ill patients toward COVID-19 among chronic disease patients. Methods: An institutional-based cross-sectional study was employed among patients with chronic diseases visiting public hospitals in Mekelle, Tigray, Ethiopia, from April to June 2021. An interviewer-administered questionnaire was used to retrieve data from systematically selected 319 chronic disease patients. The data were entered using EpiData version 4.4.2.1 and analyzed by SPSS version 23. Both bivariate and multivariate logistic regression analyses were done to identify factors associated with the outcome variables. Significance was determined at a p value of <0.05, and association was described by using an odds ratio at a 95% confidence interval. Results: A total of 319 patients with chronic diseases participated in this study, with a 100% response rate. Out of 319 study participants, 51.1% had good knowledge, 59.9% had a positive attitude, and about half (49.2%) had good practices toward the COVID-19 pandemic. Multivariate analysis revealed that study participants completed secondary school (AOR = 4.691, 95%CI = 1.846-11.918), had college or higher educational levels (AOR = 4.626, 95%CI = 1.790-11.955) were positively associated with good knowledge towards COVID 19 where as those who aged 50 and up (AOR = 0.415, 95%CI = 0.227-0.759), divorced (AOR = 0.298, 95%CI = 0.116-0.764), and widowed (AOR = 0.115, 95%CI = 0.025-0.528) were negatively associated with it. Positive attitude had a statistically significant association with sex, being male (AOR = 0.471, 95%CI = 0.265-0.837), and occupation, being merchants (AOR = 4.697, 95%CI = 1.174-18.795), private employees (AOR = 4.484, 95%CI = 1.182-17.008) and housewives (AOR = 5.292, 95%CI = 1.372-20.414). Moreover, good knowledge (AOR = 4.047,95%CI = 2.205-7.427) and a positive attitude (AOR = 5.756,95%CI = 3.244-10.211) were factors significantly associated with the good practices of study participants towards COVID-19. Conclusion: Less than two thirds of the study participants had good knowledge, attitudes, and practices overall about the COVID-19 pandemic. Health professionals and other responsible bodies should provide public education about COVID-19 and its prevention measures to chronic disease patients.
ABSTRACT
Aim: The emerging respiratory disease known as the novel coronavirus disease (COVID-19) became a global concern and was declared as a global health emergency by the World Health Organization (WHO) on March 11, 2022. This study aimed to assess knowledge, attitude, and practice and associated factors toward COVID-19 and its prevention measures among residents of Mekelle city, Tigray, Northern Ethiopia. Subject and methods: A community-based cross-sectional study was conducted among 604 residents of selected kebelles in Mekelle city, Tigray region from April to February 2022. A structured questionnaire and observation check list were used to collect the data. Multivariable logistic regression analysis was used with SPSS version 25 to identify factors associated with the outcome variables. Results: A total of 604 residents were participated in the study with 100% response. Among the total study participants (n = 604), 74.2%, 58.8%, and 39.2%, of them had good knowledge, a positive attitude, and good practice toward COVID-19 and its preventive measures, respectively. Results from the multivariate analysis showed that age, level of education, and family size were found to be significantly associated with good knowledge of study participants toward COVID-19. Additionally, occupation, family size, income level, and having knowledge about COVID-19 were significant factors associated with the attitude of the study participants toward COVID-19. Moreover, practice of study participants to prevent COVID-19 was also significantly associated with educational status, occupation status, income level, and having a positive attitude about the practice toward COVID-19 prevention. Conclusion: This study result revealed that the study participants' knowledge and attitude regarding COVID-19 were good. However, their practice toward COVID-19 and its preventive measure was poor, which will affect combating the pandemic. Therefore, continuous and effective public health education programs, community mobilization, law enforcements, and breaking siege and allowing all types of humanitarian aids in the region are urgently needed to improve knowledge, attitude, and practices toward COVID-19 and its preventive measures among the residents. Supplementary Information: The online version contains supplementary material available at 10.1007/s10389-023-01826-3.
ABSTRACT
Endocrine-disrupting compounds (EDCs) are emerging contaminants of concern (ECC) that disturb endocrine hormones and system functionality even at very low concentrations (i.e. µg/L or ng/L levels). Hence, EDCs are found in all components of the environment including surface and groundwater, wastewater, soil, outdoor and indoor air and in the contaminated foods from a variety of sources (run off from agricultural activities, sewage treatment plants, leakage from septic tanks etc.), and the effects are more severe as the majority of EDCs do not have standard regulations. The environmental mobility of EDCs is higher as conventional wastewater treatment does not degrade efficiently and the development of effective and sustainable removal technologies specifically designed for the removal of those emerging micropollutants is essential. Accordingly, EDCs cause various public health diseases such as reproductive abnormalities, obesity, various cancer types, cardiovascular risks, metabolic disorders, epigenetic alterations, autism, etc. This paper reviews the existing and emerging treatment technologies for the removal of phenolic based EDCs, such as natural estrogens (estrone (E1), 17ß-estradiol (E2), estriol (E3)), synthetic estrogen 17α-ethinylestradiol (EE2) and phenolic xenoestrogens (4-nonyl phenols (4-NP) and bisphenol-A (BPA)) from the contaminated environment. These includes advanced oxidation processes (AOP), adsorption processes, membrane based filtration, bioremediation, phytoremediation and other integrated approaches. The sustainability of EDCs removal can be assured through the use of combined processes (i.e. low-cost - biological and adsorption methods with efficient and costly - AOPs) techniques through system integration to achieve better removal efficiency than using a single treatment technique. Besides, the public health concerns and future research perspectives of EDCs are also highlighted.
