Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 5 de 5
Filter
Add more filters











Database
Language
Publication year range
1.
J Ayub Med Coll Abbottabad ; 34(2): 364-365, 2022.
Article in English | MEDLINE | ID: mdl-35576304

ABSTRACT

Dermatofibrosarcoma protuberans is a rare cutaneous malignancy. Usual sites of origin are trunk and extremities. Aetiology of the condition is not well understood but a genetic basis is explained as a reciprocal translocation t (17l;22) (q22; q13). Distant metastasis is quite rare as it is mostly a locally advancing tumour. Histopathology is the most accurate investigation to make a diagnosis. Imaging is still required to rule out distant metastasis. Surgical excision is the treatment option for stage I tumours. Imatinib, a tyrosine kinase inhibitor, has shown promising results in management of locally advanced and metastatic disease.


Subject(s)
Dermatofibrosarcoma , Skin Neoplasms , Dermatofibrosarcoma/diagnosis , Dermatofibrosarcoma/genetics , Dermatofibrosarcoma/therapy , Humans , Imatinib Mesylate/therapeutic use , Male , Skin Neoplasms/diagnosis , Skin Neoplasms/therapy , Translocation, Genetic
2.
J Coll Physicians Surg Pak ; 30(9): 989-991, 2020 Sep.
Article in English | MEDLINE | ID: mdl-33036689

ABSTRACT

Chylous ascites as first manifestation of pancreatic carcinoma is very rare. Usual presentations of pancreatic malignancy are abdominal discomfort, back pain, obstructive jaundice and duodenal obstruction. Development of chylous ascites during the course of the disease signifies poor prognosis. Malignancy and tuberculosis are the most common causes of this condition in developed and developing countries, respectively. Diagnosis is made on elevated triglyceride levels in ascitic fluid examination. Management is directed towards the treatment of primary cause and the chylous ascites. High protein and medium chain triglyceride diet is usually advised along with Orlistat for managing this condition. Peritoneovenus shunting can also be done but at the risk of complications. Our patient developed chylous ascites early in the course of the pancreatic carcinoma. CT scan abdomen was non-conclusive and cervical lymph node biopsy later on revealed that the primary disease was occult pancreatic carcinoma. Key Word: Chylous ascites, Triglyceride level, Pancreatic carcinoma.


Subject(s)
Chylous Ascites , Pancreatic Neoplasms , Biopsy , Chylous Ascites/diagnosis , Chylous Ascites/etiology , Humans , Pancreas , Pancreatic Neoplasms/complications , Pancreatic Neoplasms/diagnosis , Pancreatic Neoplasms
3.
J Pak Med Assoc ; 70(2): 351-353, 2020 Feb.
Article in English | MEDLINE | ID: mdl-32063634

ABSTRACT

Ectopic lingual thyroid along with a normally located thyroid gland is an uncommon condition caused by an aberrant descent of thyroid during embryogenesis. It is more common among females and expresses during puberty, pregnancy and menopause. It is mostly associated with hypothyroidism. Patient usually presents with complaints of dysphagia, dysphonia and suffocation. Treatment of choice depends upon the primary complaint of the patient. We present the case of a young female who underwent tracheostomy to relieve respiratory tract obstruction during puberty and was later diagnosed as a case of ectopic lingual thyroid by radioactive iodine uptake and CT scan imaging. She had an associated hypothyroidism; patient was then put on thyroxine and after making her euthyroid she was operated by transoral route and her ectopic lingual thyroid was removed. She was discharged on a maintenance dose of thyroxin.


Subject(s)
Airway Obstruction/diagnostic imaging , Hypothyroidism/diagnosis , Lingual Thyroid/diagnostic imaging , Adolescent , Airway Obstruction/etiology , Airway Obstruction/physiopathology , Deglutition Disorders/etiology , Deglutition Disorders/physiopathology , Female , Humans , Hypothyroidism/complications , Hypothyroidism/drug therapy , Hypothyroidism/physiopathology , Lingual Thyroid/complications , Lingual Thyroid/physiopathology , Lingual Thyroid/surgery , Thyroid Dysgenesis/complications , Thyroid Dysgenesis/diagnostic imaging , Thyroid Dysgenesis/physiopathology , Thyroxine/therapeutic use , Tomography, X-Ray Computed
4.
J Ayub Med Coll Abbottabad ; 31(3): 464-465, 2019.
Article in English | MEDLINE | ID: mdl-31535530

ABSTRACT

Tuberculosis continues to be a fatal infectious disease in developing countries. Despite the advances in medical sciences and introduction of potent therapeutic regimes tuberculosis has still managed to survive and prevail worldwide. It can affect many organs of body. Isolated splenic tuberculosis is uncommon in immunocompetent host and only some cases are reported internationally. Extrapulmonary tuberculosis with splenic involvement is also rare and only comes after lungs and liver. We present a case of patient presented with complaints of prolonged fever, cough and insidious onset of abdominal pain and sepsis. Exploratory laparotomy revealed spleenic abscess as incidental finding associated with tuberculous perforation of colon. She underwent double barrel colostomy and spleenectomy followed by intensive care unit admission. Measures such as awareness about the disease, early medical assistance and good compliance regarding treatment can produce positive results in combating tuberculosis and its complications.


Subject(s)
Abscess/microbiology , Colonic Diseases/complications , Intestinal Perforation/microbiology , Splenic Diseases/microbiology , Tuberculosis/complications , Abscess/surgery , Aged, 80 and over , Colonic Diseases/surgery , Colostomy , Female , Humans , Intestinal Perforation/surgery , Splenectomy , Splenic Diseases/surgery , Tuberculosis/surgery
SELECTION OF CITATIONS
SEARCH DETAIL