1.
Cell Metab
; 34(5): 651-653, 2022 05 03.
Article
in English
| MEDLINE
| ID: mdl-35508105
ABSTRACT
Chen et al. reveal an increase of phosphoglycerate dehydrogenase (PHGDH) mRNA and protein levels in two mouse models and four human cohorts in Alzheimer's disease brains compared to age- and sex-matched control brains. The increase of PHGDH expression in human brain correlates with symptomatic development and disease pathology.