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3.
Org Biomol Chem ; 22(35): 7194-7202, 2024 Sep 11.
Article in English | MEDLINE | ID: mdl-39161284

ABSTRACT

Calcium ion (Ca2+) control is an essential tool in neuronal research. Herein, we report three thiocoumarin-based, visible light-activated Ca2+ chelators with quantum yields of 0.39, 0.52, and 0.83. The chelators demonstrated an over 105-fold increase in Ca2+ binding affinity upon irradiation. These chelators are efficiently triggered by biologically safer wavelengths, rendering them excellent candidates for use in neurological research and medicine.

4.
Arch Sex Behav ; 2024 Aug 19.
Article in English | MEDLINE | ID: mdl-39160411

ABSTRACT

Low sexual desire in women partnered with men has been the subject of controversy and research over the past decades, including both as construct and diagnosis. Despite discussion surrounding the causes of low desire, there is a gap in research about how women themselves understand the causes of their low desire and the potential consequences of these causal attributions. In the current study, we investigated this by asking 130 women who had low desire and were partnered with men about their attributions for low desire. Through content analysis, we identified five attribution categories: psychological/individual, relational, biological, sociocultural, and/or sexual orientation/identity/status. Many participants chose more than one category, indicating a multifaceted nature of women's causes of low desire. We then quantitatively assessed women's feelings of responsibility for, and emotions surrounding, their low desire. Our findings indicate that the majority-but not all-of women have negative feelings about their low desire. However, the specific emotions they experience are related to their attribution patterns. This underscores the significance of investigating various facets of women's attributions regarding low desire in order to gain a more comprehensive understanding of their emotional experiences and desire overall.

5.
JAMA ; 332(8): 611, 2024 08 27.
Article in English | MEDLINE | ID: mdl-39093577
6.
JAMA ; 332(8): 610-611, 2024 08 27.
Article in English | MEDLINE | ID: mdl-39093559
17.
JAMA ; 332(5): 363, 2024 08 06.
Article in English | MEDLINE | ID: mdl-38995661
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