Clinical Effect of Hufu Copper Scraping on Shoulder-Hand Syndrome after Stroke.

Objective: To explore the clinical effect of Hufu copper scraping on shoulder-hand syndrome after stroke. Methods: A total of 60 patients with shoulder-hand syndrome after stroke admitted to the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine were enrolled between January 2020 and June 2021. According to the random number table method, they were divided into the control group (n = 30) and the intervention group (n = 30). The control group was given routine rehabilitation intervention, while the intervention group was additionally given Hufu copper scraping. The intervention effect, occurrence of adverse reactions during the intervention, pain, swelling degree of affected hands, serum calcitonin gene-related peptide (CGRP), substance P (SP), and Barthel index before and after 2 months of intervention were compared between the two groups. Results: After intervention, the total response rate of the intervention group was significantly higher than that of the control group (96.67% vs 80.00%) (P < 0.05). After intervention, the score of the visual analogue scale (VAS) and water displacement in the intervention group were lower than those in the control group (P < 0.05). After intervention, levels of CGRP and SP in the intervention group were lower than those in the control group, while the Barthel index was higher compared to the control group (P < 0.05). Conclusion: The intervention effect of Hufu copper scraping is good, which can promote the recovery of related symptoms, relieve pain and swelling of affected hands, downregulate levels of disease-promoting markers, and accelerate recovery of related function in patients with shoulder-hand syndrome after stroke.

Effectiveness of non-pharmacological interventions for treating post-stroke depression: Study protocol of an umbrella review of systematic reviews and meta-analyses.

BACKGROUND: Many systematic reviews and meta-analyses have evaluated the effectiveness of non-pharmacological therapies to improve symptoms of post-stroke depression (PSD) and reduce disability and mortality in patients with PSD. However, no research has appraised the credibility of the evidence. This study aims to summarize and evaluate the current evidence for non-pharmacological treatment of PSD and to seek effective treatment with reference to reliable evidence. METHODS: We searched the electronic databases EMBASE, MEDLINE, Cochrane Central, PubMed, PROSPERO, Web of Science, and CINAHL. We will search articles from the above database for all published meta-analyses to December 2021 to evaluate the effect of non-pharmacological treatment of PSD. Two reviewers will extract the general characteristics of the included articles, as well as participants, interventions, outcome measures, and conclusions. The quality evaluation of each systematic review will be conducted with reference to the AMSTAR 2 tool. The effect size of each review will be recalculated using either a fixed-effects or a random-effects model. Cochrane's Q test and I2 statistics will be used to evaluate the heterogeneity between studies. To determine whether a systematic review had small study effects, we will use the Egger test. We expect to extract valid evidence and classify it from strong to weak. RESULTS: The findings of this umbrella review will provide effective evidence for the non-pharmacological treatment of PSD. CONCLUSION: Our research conclusion will provide clinical staff and PSD patients with appropriate treatment recommendations. ETHICS AND DISSEMINATION: As the data were obtained from published materials, there is no need for ethical approval for this umbrella review. The findings of this umbrella review will be published in a peer-reviewed journal. INPLASY REGISTRATION NUMBER: INPLASY2021100083.

Generating Giant Vortex in a Fermi Superfluid via Spin-Orbital-Angular-Momentum Coupling.

Spin-orbital-angular-momentum (SOAM) coupling has been realized in recent experiments of Bose-Einstein condensates [Chen et al., Phys. Rev. Lett. 121, 113204 (2018)PRLTAO0031-900710.1103/PhysRevLett.121.113204 and Zhang et al., Phys. Rev. Lett. 122, 110402 (2019)PRLTAO0031-900710.1103/PhysRevLett.122.110402], where the orbital angular momentum imprinted upon bosons leads to quantized vortices. For fermions, such an exotic synthetic gauge field can provide fertile ground for fascinating pairing schemes and rich superfluid phases, which are yet to be explored. Here we demonstrate how SOAM coupling stabilizes vortices in Fermi superfluids through a unique mechanism that can be viewed as the angular analog to that of the spin-orbit-coupling-induced Fulde-Ferrell state under a Fermi surface deformation. Remarkably, the vortex size is comparable with the beam waist of Raman lasers generating the SOAM coupling, which is typically much larger than previously observed vortices in Fermi superfluids. With tunable size and core structure, these giant vortex states provide unprecedented experimental access to topological defects in Fermi superfluids.

Reduced Quantum Anomaly in a Quasi-Two-Dimensional Fermi Superfluid: Significance of the Confinement-Induced Effective Range of Interactions.

A two-dimensional (2D) harmonically trapped interacting Fermi gas is anticipated to exhibit a quantum anomaly and possesses a breathing mode at frequencies different from a classical scale-invariant value ω_{B}=2ω_{⊥}, where ω_{⊥} is the trapping frequency. The predicted maximum quantum anomaly (∼10%) has not been confirmed in experiments. Here, we theoretically investigate the zero-temperature density equation of state and the breathing mode frequency of an interacting Fermi superfluid at the dimensional crossover from three to two dimensions. We find that the simple model of a 2D Fermi gas with a single s-wave scattering length is not adequate to describe the experiments in the 2D limit, as commonly believed. A more complete description of quasi-2D leads to a much weaker quantum anomaly, consistent with the experimental observations. We clarify that the reduced quantum anomaly is due to the significant confinement-induced effective range of interactions.

Realizing Fulde-Ferrell Superfluids via a Dark-State Control of Feshbach Resonances.

We propose that the long-sought Fulde-Ferrell superfluidity with nonzero momentum pairing can be realized in ultracold two-component Fermi gases of ^{40}K or ^{6}Li atoms by optically tuning their magnetic Feshbach resonances via the creation of a closed-channel dark state with a Doppler-shifted Stark effect. In this scheme, two counterpropagating optical fields are applied to couple two molecular states in the closed channel to an excited molecular state, leading to a significant violation of Galilean invariance in the dark-state regime and hence to the possibility of Fulde-Ferrell superfluidity. We develop a field theoretical formulation for both two-body and many-body problems and predict that the Fulde-Ferrell state has remarkable properties, such as anisotropic single-particle dispersion relation, suppressed superfluid density at zero temperature, anisotropic sound velocity, and rotonic collective mode. The latter two features can be experimentally probed using Bragg spectroscopy, providing a smoking-gun proof of Fulde-Ferrell superfluidity.

BCS-BEC crossover in 2D Fermi gases with Rashba spin-orbit coupling.

We present a systematic theoretical study of the BCS-BEC crossover in two-dimensional Fermi gases with Rashba spin-orbit coupling (SOC). By solving the exact two-body problem in the presence of an attractive short-range interaction we show that the SOC enhances the formation of the bound state: the binding energy E(B) and effective mass m(B) of the bound state grows along with the increase of the SOC. For the many-body problem, even at weak attraction, a dilute Fermi gas can evolve from a BCS superfluid state to a Bose condensation of molecules when the SOC becomes comparable to the Fermi momentum. The ground-state properties and the Berezinskii-Kosterlitz-Thouless (BKT) transition temperature are studied, and analytical results are obtained in various limits. For large SOC, the BKT transition temperature recovers that for a Bose gas with an effective mass m(B). We find that the condensate and superfluid densities have distinct behaviors in the presence of SOC: the condensate density is generally enhanced by the SOC due to the increase of the molecule binding; the superfluid density is suppressed because of the nontrivial molecule effective mass m(B).