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1.
J Opt Soc Am A Opt Image Sci Vis ; 41(6): 1175-1184, 2024 Jun 01.
Article in English | MEDLINE | ID: mdl-38856433

ABSTRACT

Tungsten inert gas (TIG) welding is the main welding process in the production of stainless steel welded pipe. According to the morphological characteristics of the welding molten pool image during the TIG welding process of stainless steel welded pipes, the exact position of the tungsten needle tip is calculated using image moments. Extract the weld region in the contour of the molten pool, interpolate the contour curve based on the cubic B-spline curve interpolation method, utilize the characteristics of the S-G filter, remove the interference coordinates in the contour curve through the detrending of the contour curve, extract the weld feature points, and realize the accurate identification of weld seams. The experimental results show that the method can accurately calculate the welding deviation in the welding process.

2.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi ; 19(4): 290-4, 2002 Aug.
Article in Chinese | MEDLINE | ID: mdl-12170464

ABSTRACT

OBJECTIVE: To gain an insight into the relations between human leukocyte antigen-DRB1 (HLA-DRB1) alleles and idiopathic thrombocytopenic purpura (ITP) in children. METHODS: Polymerase chain reaction-sequence specific oligonucleotide (PCR-SSO) was used to identify DRB1 alleles of 42 children with ITP. Among them, 36 were identified for anti-GPIIb/IIIa and anti-GPIb/Ix autoantibody by modified monoclonal antibody specific immobilization of platelet antigens. RESULTS: Compared with health controls, the frequency of HLA-DRB1*17 significantly increased (P<0.05, relative risk=2.76, etiologic factor=0.1064) and the frequency of HLA-DRB1*1202 significantly decreased (P<0.025, relative risk=0.20, prophylactic factor=0.7616) in children with ITP. In comparison with patients of good response to steroids and IVIgG therapy, the frequency of HLA DRB1*11 significantly increased (Chi-square=6.091, P<0.025) in patients with a poor response, furthermore, the most of HLA-DRB1*11 positive patients were female teen-agers. Twenty-seven patients (75%) had anti GPIIb/IIIa and seventeen (47.22%) had anti_GPIb/Ix autoantibodies. The positivities of both anti_GP IIb/IIIa (P=0.02) and anti-GPIb/Ix (P=0.01) were associated with HLA-D RB1*02. However, the positivity of autoantibodies between refractory and non-refractory patients showed no significant difference. CONCLUSION: The allele of HLA-DRB1*17 seems to predict susceptibility of ITP in children, while HLA-DRB1*1202 appears to be protective to ITP. The allele of HLA DRB1*11 plays an important role in resistance to steroid and IgG therapy in children with ITP. It seems that the response to the antigenic epitope of GPIIb/IIIa and GPIb/Ix is restricted by HLA-DRB1*02, while the presence of the antibodies could not predict prognosis. In conclusion, the above preliminary findings indicate that genetic factors influence the clinical course of ITP, but the exact mechanism needs to be investigated further.


Subject(s)
Alleles , HLA-DR Antigens/genetics , Platelet Membrane Glycoproteins , Purpura, Thrombocytopenic, Idiopathic/genetics , Adolescent , Autoantibodies/blood , Child , Child, Preschool , DNA/genetics , Drug Resistance/genetics , Female , Gene Frequency , Genotype , HLA-DRB1 Chains , Humans , Immunoglobulin G/therapeutic use , Male , Platelet Glycoprotein GPIIb-IIIa Complex/immunology , Platelet Glycoprotein GPIb-IX Complex/immunology , Purpura, Thrombocytopenic, Idiopathic/blood , Purpura, Thrombocytopenic, Idiopathic/drug therapy , Steroids/therapeutic use
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