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Bioorg Med Chem Lett
; 15(3): 751-4, 2005 Feb 01.
Article
in English
| MEDLINE
| ID: mdl-15664851
ABSTRACT
The development of a series of novel quinazolinethiones and quinazolinediones as inhibitors of inosine monophosphate dehydrogenase (IMPDH) is described. The synthesis, in vitro inhibitory values for IMPDH II and in vitro inhibitory value for PBMC proliferation are discussed.