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Basilar invagination as a sequela of multisystem Langerhans' cell histiocytosis.
Nanduri, V R; Jarosz, J M; Levitt, G; Stanhope, R; Chong, W K; Pritchard, J.
J Pediatr ; 136(1): 114-8, 2000 Jan.
Article in English | MEDLINE | ID: mdl-10636985

ABSTRACT

We report the presence of basilar invagination, an unexpected and previously undescribed abnormality of the skull base, in 7 of 38 long-term survivors of multisystem Langerhans' cell histiocytosis. The abnormality is acquired, but its pathogenesis is uncertain.


Subject(s)
Bone Diseases/etiology , Histiocytosis, Langerhans-Cell/complications , Occipital Bone/pathology , Adolescent , Adult , Cerebellar Diseases/etiology , Child , Cohort Studies , Encephalocele/etiology , Female , Follow-Up Studies , Foramen Magnum/pathology , Humans , Longitudinal Studies , Magnetic Resonance Imaging , Male , Odontoid Process/pathology , Platybasia/etiology , Survivors
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