Subject(s)
Bowen's Disease , Melanoma , Skin Neoplasms , Humans , Bowen's Disease/diagnosis , Skin Neoplasms/diagnosis , Melanoma/diagnosisSubject(s)
Ecthyma , Pseudomonas Infections , Biopsy , Ecthyma/pathology , Humans , Pseudomonas Infections/pathology , Pseudomonas aeruginosa , Skin/pathologyABSTRACT
In the past decades, there was a considerable advance in regard to recognition of morphologic findings and classification of several benign and malignant vascular proliferations. In 2002, attention was called by Requena et al to a new variant of cutaneous hemangioma named acquired elastotic hemangioma. In this article, a case of acquired elastotic hemangioma is reported with documentation of clinical, dermatoscopic, histopathological, and immunohistochemical findings. A systematic review of the previously 49 reported cases is provided. The criteria for clinical and histopathological diagnosis are highlighted.
Subject(s)
Elastic Tissue/pathology , Hemangioma/pathology , Skin Neoplasms/pathology , Female , Humans , Middle AgedABSTRACT
Onychocytic matricoma is a newly described tumor of the nail matrix. Clinically, it presents with localized thickening of the nail plate and melanonychia. Histologically, it represents a benign acanthoma of onychocytes. There are 8 cases reported in the literature. A 12-year-old girl presented with localized melanonychia and concurrent thickening of the nail plate restricted to the area of pigmentation affecting the right thumb, with no history of trauma or pain. We report a case of this rare tumor occurring in late childhood and provide a comprehensive review of its clinical presentation and differential diagnosis. Both clinicians and dermatopathologists should be aware of the presentation of onychocytic matricoma and include it in their scope of diagnosis of longitudinal nail bands.
Subject(s)
Acanthoma/pathology , Nail Diseases/pathology , Skin Neoplasms/pathology , Child , Diagnosis, Differential , Female , Humans , Nail Diseases/surgery , Skin Neoplasms/surgery , ThumbABSTRACT
Abstract Onychocytic matricoma is a newly described tumor of the nail matrix. Clinically, it presents with localized thickening of the nail plate and melanonychia. Histologically, it represents a benign acanthoma of onychocytes. There are 8 cases reported in the literature. A 12-year-old girl presented with localized melanonychia and concurrent thickening of the nail plate restricted to the area of pigmentation affecting the right thumb, with no history of trauma or pain. We report a case of this rare tumor occurring in late childhood and provide a comprehensive review of its clinical presentation and differential diagnosis. Both clinicians and dermatopathologists should be aware of the presentation of onychocytic matricoma and include it in their scope of diagnosis of longitudinal nail bands.
Subject(s)
Humans , Female , Child , Skin Neoplasms/pathology , Acanthoma/pathology , Nail Diseases/pathology , Skin Neoplasms/surgery , Thumb , Diagnosis, Differential , Nail Diseases/surgerySubject(s)
Purpura/etiology , Scabies/diagnosis , Strongyloidiasis/diagnosis , Abdomen , Humans , Male , Middle Aged , Purpura/pathology , Scabies/pathology , Strongyloidiasis/pathologyABSTRACT
Melanomas can arise either de novo (70%) or from pre-existing melanocytic lesions (30%). Of the latter, most cases arise at the dermoepidermal junction from small congenital or acquired non-blue nevi while only a few arise from blue nevi, notably the cellular subtype and less commonly the common (dendritic) type. Melanomas that arise from blue nevi usually occur on the scalp with greater frequency, as in the case described. Although previous studies have discussed melanoma arising from giant congenital blue nevi, few have discussed those arising from intermediate blue nevi. We present a case of a 52-yearold man with melanoma on the scalp evolving from an intermediate congenital common blue nevus.
Subject(s)
Head and Neck Neoplasms/pathology , Melanoma/pathology , Nevus, Blue/congenital , Nevus, Blue/pathology , Scalp/pathology , Skin Neoplasms/congenital , Skin Neoplasms/pathology , Biopsy , Dermis/pathology , Fatal Outcome , Humans , Male , Middle AgedABSTRACT
Abstract: Melanomas can arise either de novo (70%) or from pre-existing melanocytic lesions (30%). Of the latter, most cases arise at the dermoepidermal junction from small congenital or acquired non-blue nevi while only a few arise from blue nevi, notably the cellular subtype and less commonly the common (dendritic) type. Melanomas that arise from blue nevi usually occur on the scalp with greater frequency, as in the case described. Although previous studies have discussed melanoma arising from giant congenital blue nevi, few have discussed those arising from intermediate blue nevi. We present a case of a 52-yearold man with melanoma on the scalp evolving from an intermediate congenital common blue nevus.
Subject(s)
Humans , Male , Middle Aged , Scalp/pathology , Skin Neoplasms/congenital , Nevus, Blue/congenital , Nevus, Blue/pathology , Head and Neck Neoplasms/pathology , Melanoma/pathology , Biopsy , Fatal Outcome , Dermis/pathologyABSTRACT
Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clinical manifestation of leprosy, resulting in a delay in the diagnosis due to unusual clinical presentation. The patient had clinical and histopathological features reminiscent of Sweet's syndrome associated with clusters of vacuolated histiocytes containing acid-fast bacilli isolated or forming globi. Herein, it is discussed how to recognize type 2 leprosy reaction with Sweet's syndrome features, the differential diagnosis with type 1 leprosy reaction and the treatment options. When this kind of reaction is the first clinical presentation of leprosy, the correct diagnosis might be not suspected clinically, and established only with histopathologic evaluation.
Subject(s)
Leprosy, Multibacillary/diagnosis , Sweet Syndrome/diagnosis , Adult , Erythema/diagnosis , Female , Histiocytes/pathology , Humans , Leprostatic Agents/therapeutic use , Leprosy, Multibacillary/complications , Leprosy, Multibacillary/drug therapy , Leprosy, Multibacillary/pathology , Neutrophils/pathology , Prednisone/therapeutic use , Sweet Syndrome/drug therapy , Sweet Syndrome/etiology , Sweet Syndrome/pathology , Thalidomide/therapeutic useABSTRACT
Abstract Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clinical manifestation of leprosy, resulting in a delay in the diagnosis due to unusual clinical presentation. The patient had clinical and histopathological features reminiscent of Sweet's syndrome associated with clusters of vacuolated histiocytes containing acid-fast bacilli isolated or forming globi. Herein, it is discussed how to recognize type 2 leprosy reaction with Sweet's syndrome features, the differential diagnosis with type 1 leprosy reaction and the treatment options. When this kind of reaction is the first clinical presentation of leprosy, the correct diagnosis might be not suspected clinically, and established only with histopathologic evaluation.
Subject(s)
Humans , Female , Adult , Sweet Syndrome/diagnosis , Leprosy, Multibacillary/diagnosis , Thalidomide/therapeutic use , Prednisone/therapeutic use , Sweet Syndrome/etiology , Sweet Syndrome/pathology , Sweet Syndrome/drug therapy , Erythema/diagnosis , Leprosy, Multibacillary/complications , Leprosy, Multibacillary/pathology , Leprosy, Multibacillary/drug therapy , Histiocytes/pathology , Leprostatic Agents/therapeutic use , Neutrophils/pathologyABSTRACT
Cytomegalovirus is an opportunistic virus that commonly affects immunosuppressed patients. Cutaneous involvement by this virus is rare and occurs in significantly immunocompromised hosts, with a poor prognosis. Skin ulcers may represent the first sign of systemic infection by cytomegalovirus in these patients. Herein, a case of a systemic infection by Cytomegalovirus presenting as genital and oral ulcers in a kidney-transplant recipient is reported.
Subject(s)
Cytomegalovirus Infections/pathology , Immunocompetence , Kidney Transplantation/adverse effects , Skin Diseases, Viral/pathology , Aged , Cytomegalovirus Infections/immunology , Humans , Male , Polymerase Chain Reaction , Skin Diseases, Viral/immunology , Skin Ulcer/pathology , Skin Ulcer/virologyABSTRACT
Abstract Cytomegalovirus is an opportunistic virus that commonly affects immunosuppressed patients. Cutaneous involvement by this virus is rare and occurs in significantly immunocompromised hosts, with a poor prognosis. Skin ulcers may represent the first sign of systemic infection by cytomegalovirus in these patients. Herein, a case of a systemic infection by Cytomegalovirus presenting as genital and oral ulcers in a kidney-transplant recipient is reported.
Subject(s)
Aged , Humans , Male , Cytomegalovirus Infections/pathology , Immunocompetence , Kidney Transplantation/adverse effects , Skin Diseases, Viral/pathology , Cytomegalovirus Infections/immunology , Polymerase Chain Reaction , Skin Diseases, Viral/immunology , Skin Ulcer/pathology , Skin Ulcer/virologyABSTRACT
Milker's nodule is an occupational viral skin disease of universal distribution, caused by the Paravaccinia virus and that occurs in individuals who deal with dairy cattle herds. We describe a case acquired due to lack of use of PPE (Personal Protective Equipment) and perform a literature review.
Subject(s)
Hand Dermatoses/pathology , Occupational Diseases/pathology , Poxviridae Infections/pathology , Skin Diseases, Viral/pathology , Animals , Biopsy , Cattle , Disease Progression , Female , Humans , Middle Aged , Pseudocowpox VirusABSTRACT
Abstract Milker's nodule is an occupational viral skin disease of universal distribution, caused by the Paravaccinia virus and that occurs in individuals who deal with dairy cattle herds. We describe a case acquired due to lack of use of PPE (Personal Protective Equipment) and perform a literature review.
Subject(s)
Humans , Animals , Female , Middle Aged , Cattle , Skin Diseases, Viral/pathology , Poxviridae Infections/pathology , Hand Dermatoses/pathology , Occupational Diseases/pathology , Biopsy , Pseudocowpox Virus , Disease ProgressionABSTRACT
Doença rara, descrita por Pinkus em 1957, a alopecia mucinosa pertence às alopecias cicatriciais. É assim denominada pelo acúmulo de mucina e linfócitos na porção infundibular do aparelho pilossebáceo, promovendo destruição total e irreversível do local afetado. De etiologia desconhecida, clinicamente se manifesta em placas, geralmente normocrômicas, bem demarcadas, composta por pápulas com evidente proeminência folicular. A ausência de sintomas é a regra. Sua classificação como micose fungoide incipiente ainda não é consenso. Com pico bimodal de incidência costuma manifestar-se em crianças ou idosos, através de diferentes quadros clínicos, prognósticos e associações. Não existem, até o presente momento, estudos de dermatoscopia nessa rara entidade. Descrevemos uma apresentação atípica da doença e propomos seus achados dermatoscópicos.