ABSTRACT
<p><b>OBJECTIVE</b>To study the effects of dopamine and phenylephrine for treatment of hypotension during cesarean section under combined spinal epidural anesthesia (CSEA) on the stereology of the placenta.</p><p><b>METHODS</b>Forty puerperants undergoing cesarean section under CSEA were randomly divided into dopamine group and phenylephrine group. Ropivacaine (16 mg) was administered immediately after spinal anethesia. Blood pressure was maintained near the baseline by adjusting the drug infusion rate. Fetal blood gas, Apgar score, and placental villus microvascular stereological changes were observed during the operation.</p><p><b>RESULTS</b>The microvascular density was significantly lower in dopamine group than in phenylephrine group (P<0.05). Phenylephrine group showed significantly lower umbilical artery blood pH than dopamine group (P<0.05). The Apgar score and blood pressure were comparable between the two groups (P>0.05). Compared to the baseline, both of the two groups showed significantly lowered heart rate during the operation (P<0.01).</p><p><b>CONCLUSION</b>Dopamine is associated with the risk of fetal acidosis. Phenylephrine is helpful for preventing hypotension by increasing placental blood flow and improving oxygen supply to ensure maternal and fetal safety during cesarean section.</p>
Subject(s)
Female , Humans , Infant, Newborn , Pregnancy , Amides , Anesthesia, Spinal , Apgar Score , Blood Gas Analysis , Blood Pressure , Cesarean Section , Dopamine , Fetal Blood , Fetus , Heart Rate , Hypotension , Drug Therapy , Oxygen , Phenylephrine , Placenta , Physiology , Vasoconstrictor AgentsABSTRACT
OBJECTIVE:To provide references for drugstores to launch pharmaceutical care.METHODS:The consents,methods and obstacles in launching pharmaceutical care for drugstores were analyzed.RESULTS&CONCLUSION:The launching of pharmaceutical care in drugstores can not only considerably ensure the benefits of consumers in drug use,but also raise their own core competitive power.
ABSTRACT
OBJECTIVE:To study the integrated efficacy of Folium Ginkgo Tablets and the general regularity of the effect on the hypertensive patients' quality of life (QOL).METHODS:116 moderate hypertensive patients took the placebo for two weeks were randomly divided into treatment and control groups.Both groups were treated with Metoprolol,while the treatment group was added with Folium Ginkgo Tablets,and time of therapy was 24 weeks.Croog scale on quality of life checklist was used as benchmark for designing the QQL test questionnaire.RESULTS:The effect rates for treatment and control groups’overall relief efficacy were 96.43%and 80.00%respectively(P0.05).CONCLUSION:Folium Ginkgo Tablets not only had good efficacy and stable pressure-relief effect on the hypertensive patients,but also significantly improved patients QOL.