ABSTRACT
The efficacy of immunomodulating agent T-activin has been studied in adult BALB/C mice infected with Coxsackie B1 virus. Optical, electron microscopic and immunological tests have shown that T-activin protects myocardium and modulates immune disorders in mice with viral myocarditis.
Subject(s)
Adjuvants, Immunologic/therapeutic use , Coxsackievirus Infections/drug therapy , Myocarditis/drug therapy , Peptides/therapeutic use , Thymus Extracts/therapeutic use , Animals , Coxsackievirus Infections/immunology , Coxsackievirus Infections/pathology , Female , Male , Mice , Mice, Inbred BALB C , Myocarditis/immunology , Myocarditis/pathology , Myocardium/pathology , Peptides/administration & dosage , Rosette Formation , T-Lymphocytes/immunology , Thymus Extracts/administration & dosage , Time FactorsABSTRACT
Results of immunomorphological studies carried out on 48 stomachs resected for duodenal ulcerous disease are reported. Mucosal inflammation described as "immune" and varying in degree in an age-related manner (being lowest in patients aged over 60) was noted in the pyloric part of the stomach. It is shown that the immune inflammation of gastric mucosa in duodenal ulcer patients is mediated by humoral immunopathological mechanisms involving, essentially, locally produced antibody, although delayed-type reactions are also possibly implicated.